2025 Journal Article Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivityYao, Shuyang, Harder, Arvid, Darki, Fahimeh, Chang, Yu-Wei, Li, Ang, Nikouei, Kasra, Volpe, Giovanni, Lundström, Johan N., Zeng, Jian, Wray, Naomi R., Lu, Yi, Sullivan, Patrick F. and Hjerling-Leffler, Jens (2025). Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity. Nature Communications, 16 (1) 395, 1-18. doi: 10.1038/s41467-024-55611-1 |
2025 Journal Article Genome-wide copy number variation association study in anorexia nervosaWalker, Alicia, Karlsson, Robert, Szatkiewicz, Jin P., Thornton, Laura M., Yilmaz, Zeynep, Leppä, Virpi M., Savva, Androula, Lin, Tian, Sidorenko, Julia, McRae, Allan, Kirov, George, Davies, Helena L., Fundín, Bengt T., Chawner, Samuel J. R. A., Song, Jie, Borg, Stina, Wen, Jia, Watson, Hunna J., Munn-Chernoff, Melissa A., Baker, Jessica H., Gordon, Scott, Berrettini, Wade H., Brandt, Harry, Crawford, Steven, Halmi, Katherine A., Kaplan, Allan S., Kaye, Walter H., Mitchell, James, Strober, Michael ... Wray, Naomi R. (2025). Genome-wide copy number variation association study in anorexia nervosa. Molecular Psychiatry, 30 (5) 867, 2009-2016. doi: 10.1038/s41380-024-02811-2 |
2025 Journal Article Familial coaggregation and shared familiality of functional and internalizing disorders in the Lifelines cohortBos, Martje, Monden, Rei, Wray, Naomi R., Zhou, Yiling, Kendler, Kenneth S., Rosmalen, Judith G. M., van Loo, Hanna M. and Snieder, Harold (2025). Familial coaggregation and shared familiality of functional and internalizing disorders in the Lifelines cohort. Psychological Medicine, 55 e126, 55. doi: 10.1017/s003329172500100x |
2024 Journal Article Distinct genetic liability profiles define clinically relevant patient strata across common diseasesTrastulla, Lucia, Dolgalev, Georgii, Moser, Sylvain, Jiménez-Barrón, Laura T., Andlauer, Till F. M., von Scheidt, Moritz, Ruderfer, Douglas M., Ripke, Stephan, McQuillin, Andrew, Stahl, Eli A., Domenici, Enrico, Adolfsson, Rolf, Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Bacanu, Silviu A., Begemann, Martin, Belliveau, Richard A., Bene, Judit, Bergen, Sarah E., Bevilacqua, Elizabeth, Bigdeli, Tim B., Black, Donald W., Blackwood, Douglas H. R., Borglum, Anders D., Bramon, Elvira, Bruggeman, Richard ... Ziller, Michael J. (2024). Distinct genetic liability profiles define clinically relevant patient strata across common diseases. Nature Communications, 15 (1) 5534, 1-28. doi: 10.1038/s41467-024-49338-2 |
2024 Journal Article Sex-specific association between genetic risk of psychiatric disorders and cardiovascular diseasesJiang, Jiayue-Clara, Singh, Kritika, Nitin, Rachana, Davis, Lea K., Wray, Naomi R. and Shah, Sonia (2024). Sex-specific association between genetic risk of psychiatric disorders and cardiovascular diseases. Circulation: Genomic and Precision Medicine, 17 (6) e004685, 1-12. doi: 10.1161/circgen.124.004685 |
2024 Conference Publication A Multi-omic QTL Analysis Of Major Depressive DisorderNisbet, Laurence, Shen, Xueyi, Wray, Naomi and McIntosh, Andrew (2024). A Multi-omic QTL Analysis Of Major Depressive Disorder. World Congress of Psychiatric Genetics WCPG 2024, Singapore, 15-19 October 2024. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2024.08.357 |
2024 Conference Publication Mendelian Randomization – What Are The Promises?Schwab, Sibylle and Wray, Naomi (2024). Mendelian Randomization – What Are The Promises?. World Congress of Psychiatric Genetics WCPG 2024, Singapore, 15-19 October 2024. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2024.08.028 |
2024 Conference Publication Latest Insights From Multi-ancestry Fine-mapping In Psychiatric DisordersKoromina, Maria and Wray, Naomi (2024). Latest Insights From Multi-ancestry Fine-mapping In Psychiatric Disorders. World Congress of Psychiatric Genetics WCPG 2024, Singapore, 15-19 October 2024. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2024.08.033 |
2024 Conference Publication The Application Of Mendelian Randomization Method To Exposure-outcome Pairs With A Non-linear RelationshipZhu, Zhihong, Wray, Naomi, McGrath, John and Vilhjálmsson, Bjarni (2024). The Application Of Mendelian Randomization Method To Exposure-outcome Pairs With A Non-linear Relationship. World Congress of Psychiatric Genetics WCPG 2024, Singapore, 15-19 October 2024. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2024.08.032 |
2024 Conference Publication Genome-wide Fine-mapping Improves Identification Of Causal VariantsZeng, Jian, Wu, Yang, Zheng, Zhili, Thibaut, Loic, Goddard, Michael, Wray, Naomi and Visscher, Peter (2024). Genome-wide Fine-mapping Improves Identification Of Causal Variants. World Congress of Psychiatric Genetics WCPG 2024, Singapore, 15-19 October 2024. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2024.08.037 |
2024 Conference Publication AMBER: Antidepressant Medications: Biology, Exposure And ResponseLewis, Cathryn, Fletcher-Watson, Sue, Whalley, Heather, Shah, Sonia, Pain, Oliver, Wray, Naomi and McIntosh, Andrew (2024). AMBER: Antidepressant Medications: Biology, Exposure And Response. World Congress of Psychiatric Genetics WCPG 2024, Singapore, 15-19 October 2024. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2024.08.452 |
2024 Conference Publication Cohort Profile: Improving Outcomes Of Mental Health (IOMH) A Longitudinal Clinical Study Of Families With Children With Neurodevelopmental ProblemsGalligan, Dana, Payne, Leanne, Sullivan, Daniel, Bhadravathi Lokeshappa, Madhura, Ziser, Laura, Nunn, Lorelle, Wallace, Leanne, Sanders, Matthew, Cobham, Vanessa, Wray, Naomi, Henders, Anjali, Byrne, Enda, Heussler, Helen and Middeldorp, Christel M. (2024). Cohort Profile: Improving Outcomes Of Mental Health (IOMH) A Longitudinal Clinical Study Of Families With Children With Neurodevelopmental Problems. World Congress of Psychiatric Genetics WCPG 2024, Singapore, 15-19 October 2024. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2024.08.469 |
2024 Journal Article Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohortsAdams, Mark J., Thorp, Jackson G., Jermy, Bradley S., Kwong, Alex S. F., Kõiv, Kadri, Grotzinger, Andrew D., Nivard, Michel G., Marshall, Sally, Milaneschi, Yuri, Baune, Bernhard T., Müller-Myhsok, Bertram, Penninx, Brenda W. J. H., Boomsma, Dorret I., Levinson, Douglas F., Breen, Gerome, Pistis, Giorgio, Grabe, Hans J., Tiemeier, Henning, Berger, Klaus, Rietschel, Marcella, Magnusson, Patrik K., Uher, Rudolf, Hamilton, Steven P., Lucae, Susanne, Lehto, Kelli, Li, Qingqin S., Byrne, Enda M., Hickie, Ian B., Martin, Nicholas G. ... Derks, Eske M. (2024). Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts. Psychological Medicine, 54 (12), 3459-3468. doi: 10.1017/s0033291724001880 |
2024 Journal Article Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohortsAdams, Mark J., Thorp, Jackson G., Jermy, Bradley S., Kwong, Alex S. F., Koiv, Kadri, Grotzinger, Andrew D., Nivard, Michel G., Marshall, Sally, Milaneschi, Yuri, Baune, Bernhard T., Mueller-Myhsok, Bertram, Penninx, Brenda W. J. H., Boomsma, Dorret I., Levinson, Douglas F., Breen, Gerome, Pistis, Giorgio, Grabe, Hans J., Tiemeier, Henning, Berger, Klaus, Rietschel, Marcella, Magnusson, Patrik K., Uher, Rudolf, Hamilton, Steven P., Lucae, Susanne, Lehto, Kelli, Li, Qingqin S., Byrne, Enda M., Hickie, Ian B., Martin, Nicholas G. ... Derks, Eske M. (2024). Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts. Psychological Medicine, 54 (12), 3459-3468. doi: 10.1017/S0033291724001880 |
2024 Journal Article Patterns of stressful life events and polygenic scores for five mental disorders and neuroticism among adults with depressionCrouse, Jacob J., Park, Shin Ho, Byrne, Enda M., Mitchell, Brittany L., Scott, Jan, Medland, Sarah E., Lin, Tian, Wray, Naomi R., Martin, Nicholas G. and Hickie, Ian B. (2024). Patterns of stressful life events and polygenic scores for five mental disorders and neuroticism among adults with depression. Molecular Psychiatry, 29 (9), 2765-2773. doi: 10.1038/s41380-024-02492-x |
2024 Conference Publication Sex Matters in Cardiovascular Research: A Higher Genetic Risk of Depression is a Greater Risk Factor for Cardiovascular Diseases in FemalesJiang, J., Singh, K., Nitin, R., Davis, L., Wray, N. and Shah, S. (2024). Sex Matters in Cardiovascular Research: A Higher Genetic Risk of Depression is a Greater Risk Factor for Cardiovascular Diseases in Females. 72nd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Perth, WA Australia, 1-4 August 2024. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2024.06.412 |
2024 Journal Article R2ROC: an efficient method of comparing two or more correlated AUC from out-of-sample prediction using polygenic scoresMomin, Md. Moksedul, Wray, Naomi R. and Lee, S. Hong (2024). R2ROC: an efficient method of comparing two or more correlated AUC from out-of-sample prediction using polygenic scores. Human Genetics, 143 (9-10), 1193-1205. doi: 10.1007/s00439-024-02682-1 |
2024 Journal Article Exercise rejuvenates microglia and reverses T cell accumulation in the aged female mouse brainChauquet, Solal, Willis, Emily F., Grice, Laura, Harley, Samuel B. R., Powell, Joseph E., Wray, Naomi R., Nguyen, Quan, Ruitenberg, Marc J., Shah, Sonia and Vukovic, Jana (2024). Exercise rejuvenates microglia and reverses T cell accumulation in the aged female mouse brain. Aging Cell, 23 (7) e14172, e14172. doi: 10.1111/acel.14172 |
2024 Journal Article Genetic influence on within-person longitudinal change in anthropometric traits in the UK BiobankKemper, Kathryn E., Sidorenko, Julia, Wang, Huanwei, Hayes, Ben J., Wray, Naomi R., Yengo, Loic, Keller, Matthew C., Goddard, Michael and Visscher, Peter M. (2024). Genetic influence on within-person longitudinal change in anthropometric traits in the UK Biobank. Nature Communications, 15 (1) 3776, 3776. doi: 10.1038/s41467-024-47802-7 |
2024 Journal Article Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestriesZheng, Zhili, Liu, Shouye, Sidorenko, Julia, Wang, Ying, Lin, Tian, Yengo, Loic, Turley, Patrick, Ani, Alireza, Wang, Rujia, Nolte, Ilja M., Snieder, Harold, Aguirre-Gamboa, Raul, Deelen, Patrick, Franke, Lude, Kuivenhoven, Jan A., Lopera Maya, Esteban A., Sanna, Serena, Swertz, Morris A., Vonk, Judith M., Wijmenga, Cisca, Yang, Jian, Wray, Naomi R., Goddard, Michael E., Visscher, Peter M., Zeng, Jian and LifeLines Cohort Study (2024). Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries. Nature Genetics, 56 (5), 1-11. doi: 10.1038/s41588-024-01704-y |