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2026 Journal Article Association between polygenic liability to depression and lifetime depression in at-risk adolescentsByrne, Enda M., Gillespie, Nathan A., Najman, Jake M., Henders, Anjali K., Mitchell, Brittany L., Dwyer, Dominic, Hartmann, Simon, Cavve, Blake S., Amminger, G. Paul, Clark, Scott, Gao, Caroline, Lin, Ashleigh, Schmaal, Lianne, Thompson, Andrew, Wood, Stephen J., Wigman, J.T.W, Yung, Alison R., Medland, Sarah E., Crouse, Jacob J., Scott, Jan, Scott, James G., Williams, Gail M., Nelson, Barnaby, Martin, Nicholas G., Hickie, Ian B., Wray, Naomi R. and Middeldorp, Christel M. (2026). Association between polygenic liability to depression and lifetime depression in at-risk adolescents. Molecular Psychiatry, 1-9. doi: 10.1038/s41380-026-03917-5 |
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2026 Journal Article F17. IMMUNE-BRAIN POLYGENIC RISK ARCHITECTURE AND CLINICAL HETEROGENEITY IN PSYCHIATRIC DISORDERSMellon-Whelan, Aisling, McGrath, Isabelle, Wray, Naomi and Lynall, Mary-Ellen (2026). F17. IMMUNE-BRAIN POLYGENIC RISK ARCHITECTURE AND CLINICAL HETEROGENEITY IN PSYCHIATRIC DISORDERS. European Neuropsychopharmacology, 111 113412, 113412. doi: 10.1016/j.euroneuro.2026.113412 |
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2026 Journal Article T8. DISENTANGLING CAUSAL AND CORRELATED IMMUNE SIGNALS IN PSYCHIATRIC DISORDERS USING MULTI-TISSUE FUNCTIONAL GENOMICSMcGrath, Isabelle, Mellon-Whelan, Aisling, Walker, Alicia, Zhou, Ruolan, Wray, Naomi and Lynall, Mary-Ellen (2026). T8. DISENTANGLING CAUSAL AND CORRELATED IMMUNE SIGNALS IN PSYCHIATRIC DISORDERS USING MULTI-TISSUE FUNCTIONAL GENOMICS. European Neuropsychopharmacology, 111 113265, 113265. doi: 10.1016/j.euroneuro.2026.113265 |
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2026 Journal Article THE SHARED GENETICS BETWEEN BRAIN STRUCTURE AND PSYCHIATRIC DISORDERS: FROM GWAS TO DEVELOPMENTAL MECHANISMSHe, Yuankai, Ebneabassi, Amir, Gu, Yuanjun, Riegis, Clara, Pearson, Bess, Polimanti, Renato, Grove, Jakob, Børglum, Anders, Astle, Duncan, Rittman, Tim, Wray, Naomi, Won, Hyejung, Bethlehem, Richard A.I., Bullmore, Edward and Warrier, Varun (2026). THE SHARED GENETICS BETWEEN BRAIN STRUCTURE AND PSYCHIATRIC DISORDERS: FROM GWAS TO DEVELOPMENTAL MECHANISMS. European Neuropsychopharmacology, 111 112978, 112978. doi: 10.1016/j.euroneuro.2026.112978 |
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2026 Journal Article A GWAS META-ANALYSIS OF PSYCHOTIC DEPRESSION LEVERAGING HEALTH-RECORD, PRESCRIPTION AND SELF-REPORT DATAMcGrath, Isabelle, Group, PGC-MDD Working, Wray, Naomi and Lynall, Mary-Ellen (2026). A GWAS META-ANALYSIS OF PSYCHOTIC DEPRESSION LEVERAGING HEALTH-RECORD, PRESCRIPTION AND SELF-REPORT DATA. European Neuropsychopharmacology, 111 112983, 112983. doi: 10.1016/j.euroneuro.2026.112983 |
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2026 Journal Article 67. MIND THE GAP: QUANTIFYING AND MITIGATING THE IMPACT OF VARIANT MISSINGNESS ON POLYGENIC SCORES WITHIN THE GENOPRED PIPELINEPain, Oliver, Wang, Xiaotong, Visscher, Peter and Wray, Naomi (2026). 67. MIND THE GAP: QUANTIFYING AND MITIGATING THE IMPACT OF VARIANT MISSINGNESS ON POLYGENIC SCORES WITHIN THE GENOPRED PIPELINE. European Neuropsychopharmacology, 111 113094, 113094. doi: 10.1016/j.euroneuro.2026.113094 |
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2026 Journal Article F117. GENETIC LIABILITY TO ANTIPSYCHOTIC MEDICATION SIDE-EFFECTS IN THE UK BIOBANKProctor, Sasha, McGrath, Isabelle, Halstead, Sean, Pillinger, Toby, Upthegrove, Rachel, Wray, Naomi and Yap, Chloe (2026). F117. GENETIC LIABILITY TO ANTIPSYCHOTIC MEDICATION SIDE-EFFECTS IN THE UK BIOBANK. European Neuropsychopharmacology, 111 113512, 113512. doi: 10.1016/j.euroneuro.2026.113512 |
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2026 Journal Article ONE MODEL DOES NOT FIT ALL: HETEROGENEITY IN POLYGENIC PROFILES OF ADHD ACROSS FOUR DEVELOPMENTAL STAGESGe, Fenfen, Wang, Yue, Agerbo, Esben, Benros, Michael, Wray, Naomi, Demontis, Ditte, Musliner, Katherine, Bo Mortensen, Preben, Petersen, Liselotte and Vilhjalmsson, Bjarni (2026). ONE MODEL DOES NOT FIT ALL: HETEROGENEITY IN POLYGENIC PROFILES OF ADHD ACROSS FOUR DEVELOPMENTAL STAGES. European Neuropsychopharmacology, 111 112989, 112989. doi: 10.1016/j.euroneuro.2026.112989 |
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2026 Journal Article THE PREDICTION OF SYMPTOM SEVERITY IN CHILDREN AND PARENTS IN A CLINICAL COHORT OF FAMILIES WITH CHILDREN WITH NEURODEVELOPMENTAL PROBLEMSMiddeldorp, Christel M., Galligan, Dana, Gangaraju, Swathi, Wray, Naomi and Byrne, Enda (2026). THE PREDICTION OF SYMPTOM SEVERITY IN CHILDREN AND PARENTS IN A CLINICAL COHORT OF FAMILIES WITH CHILDREN WITH NEURODEVELOPMENTAL PROBLEMS. European Neuropsychopharmacology, 111 113018, 113018. doi: 10.1016/j.euroneuro.2026.113018 |
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2026 Journal Article An Internal-Standard-Integrated Digital SERS Immunoassay for Accurate and Precise Trace-Level Cytokine Quantification in PlasmaZhang, Yiwen, Farokhinejad, Fahimeh, Crouse, Jacob J., Shin, Mirim, Henders, Anjali K., Wallace, Leanne M., Lobb, Richard J., Antaw, Fiach, Wray, Naomi R., Hickie, Ian B., Wuethrich, Alain and Trau, Matt (2026). An Internal-Standard-Integrated Digital SERS Immunoassay for Accurate and Precise Trace-Level Cytokine Quantification in Plasma. Analytical Chemistry. doi: 10.1021/acs.analchem.6c03298 |
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2026 Journal Article Atypical depression is associated with a distinct clinical, neurobiological, treatment response, and polygenic risk profileShin, Mirim, Crouse, Jacob J., Lin, Tian, Byrne, Enda M., Mitchell, Brittany L., Lind, Penelope A., Parker, Richard, Mckenna, Sarah, Tonini, Emiliana, Carpenter, Joanne S., Merikangas, Kathleen R., Wray, Naomi R., Medland, Sarah E., Martin, Nicholas G. and Hickie, Ian B. (2026). Atypical depression is associated with a distinct clinical, neurobiological, treatment response, and polygenic risk profile. Biological Psychiatry, 100 (5), 525-535. doi: 10.1016/j.biopsych.2026.01.003 |
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2026 Journal Article Optimizing study design for clinically useful peripheral molecular biomarker discovery in psychiatry: a reviewYap, Chloe X., Henders, Anjali K., Wray, Naomi R. and Upthegrove, Rachel (2026). Optimizing study design for clinically useful peripheral molecular biomarker discovery in psychiatry: a review. JAMA Psychiatry. doi: 10.1001/jamapsychiatry.2026.2299 |
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2026 Journal Article Genome-wide genetic overlap between fear-based disorders and generalised anxiety disorderter Kuile, Abigail R., Mitchell, Brittany L., Lee, Sang Hyuck, Morneau-Vaillancourt, Geneviève, Skelton, Megan, Coleman, Jonathan R. I., Davies, Helena L., Mundy, Jessica, Peel, Alicia J., Hübel, Christopher, Davies, Molly R., Fürtjes, Anna E., Ahmad, Zain, Lin, Yuhao, Adey, Brett N., McGregor, Thomas, Palmos, Alish, Zvrskovec, Johan, Hotopf, Matthew, Kalsi, Gursharan, Smith, Daniel J., Veale, David, Walters, James T. R., Armour, Chérie, Hirsch, Colette R., McIntosh, Andrew M., Wray, Naomi R., Medland, Sarah E., Byrne, Enda M. ... Eley, Thalia C. (2026). Genome-wide genetic overlap between fear-based disorders and generalised anxiety disorder. Molecular Psychiatry, 1-14. doi: 10.1038/s41380-026-03677-2 |
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2026 Journal Article Correction: “There’s no representation”: a qualitative study of attitudes and motivations towards genomic research participation among Australian South AsiansNathan, Vaishnavi, Akbar, Heena, McInerney-Leo, Aideen, Gilroy, Deborah, Henders, Anjali, Naresh, Reema, Choudhury, Nahid, Waqar, Maleeha, Shah, Sonia, Yanes, Tatiane, on behalf of the South Asian Genes and Health in Australia (SAGHA) research team, Atherton, John, Greaves, Kim, McGaughran, Julie, McInerney-Leo, Aideen, Mehta, Divya, Villani, Rehan Marie, Wallis, Katharine and Wray, Naomi R. (2026). Correction: “There’s no representation”: a qualitative study of attitudes and motivations towards genomic research participation among Australian South Asians. European Journal of Human Genetics, 34 (8), 1190-1190. doi: 10.1038/s41431-026-02157-z |
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2026 Journal Article Integrating multi-omics summary data identifies candidate molecular mechanisms for major depressionNisbet, Laurence, Wu, Yang, Adams, Mark, Lynall, Mary-Ellen, Hjerling-Leffler, Jens, Wray, Naomi R., McIntosh, Andrew M. and Shen, Xueyi (2026). Integrating multi-omics summary data identifies candidate molecular mechanisms for major depression. Biological Psychiatry, 99 (12), 1120-1129. doi: 10.1016/j.biopsych.2025.11.024 |
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2026 Journal Article Genome-wide meta-analysis of quantitatively measured generalized anxiety symptoms in individuals of European ancestrySkelton, Megan, Mitchell, Brittany L., Assary, Elham, Li, Danyang, Morneau-Vaillancourt, Genevieve, Murphy, Alan E., ter Kuile, Abigail R., Wang, Rujia, Adams, Mark J., Byrne, Enda M., Corfield, Elizabeth C., Grimes, Poppy Z., Hannigan, Laurie J., Hu, Jihua, Kõiv, Kadri, Kwong, Alex S. F., Papiol, Sergi, Pettersen, Johanne H., Pistis, Giorgio, Castelao, Enrique, Strom, Nora I., van der Most, Peter J., Anxiety Disorders Working Group of the Psychiatric Genomics Consortium, Bacanu, Silviu-Alin, Cheesman, Rosa, Purves, Kirstin L., Gedik, Hüseyin, Faucon, Annika B., Singh, Kritika ... Eley, Thalia C. (2026). Genome-wide meta-analysis of quantitatively measured generalized anxiety symptoms in individuals of European ancestry. Nature Human Behaviour, 10 (8), 1-15. doi: 10.1038/s41562-026-02476-7 |
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2026 Journal Article Strategic Amyotrophic Lateral Sclerosis Australia–Systems Genomics Consortium (SALSA-SGC): cohort profileHenders, Anjali K., Ziser, Laura, Garton, Fleur C., Adams, Lorel, Ernst, Karalyn, Furlong, Sarah, Heads, Judith Anne, Heggie, Susan, Krasniqi, Ruth, Bhadravathi Lokeshappa, Madhura, Mazumder, Srestha, McNamara, Elyshia, MacShane, Amanda, Mekhael, Linda, Nunn, Lorelle, Orden, Bronwen, Ryder, Julie, Thorpe, Kathryn, Toubia, Marie, Wallace, Leanne M., Wickremeratne, Dina, Windebank, Emma, Benyamin, Beben, Ngo, Shyuan, Nicholson, Garth, Pamphlett, Roger, Steyn, Frederik J., Visscher, Peter M., Willams, Kelly L. ... Wray, Naomi R. (2026). Strategic Amyotrophic Lateral Sclerosis Australia–Systems Genomics Consortium (SALSA-SGC): cohort profile. BMJ Open, 16 (6) e110906, 1-10. doi: 10.1136/bmjopen-2025-110906 |
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2026 Journal Article “There’s no representation”: a qualitative study of attitudes and motivations towards genomic research participation among Australian South AsiansNathan, Vaishnavi, Akbar, Heena, McInerney-Leo, Aideen, Gilroy, Deborah, Henders, Anjali, Naresh, Reema, Choudhury, Nahid, Waqar, Maleeha, Shah, Sonia, Yanes, Tatiane, on behalf of the South Asian Genes and Health in Australia (SAGHA) research team, Atherton, John, Greaves, Kim, McGaughran, Julie, Mehta, Divya, Villani, Rehan Marie, Wallis, Katharine and Wray, Naomi R. (2026). “There’s no representation”: a qualitative study of attitudes and motivations towards genomic research participation among Australian South Asians. European Journal of Human Genetics, 34 (8), 1-10. doi: 10.1038/s41431-026-02129-3 |
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2026 Journal Article Extensive antagonistic variants across the human genomeBian, Beilei, Hivert, Valentin, Wray, Naomi R. and McRae, Allan F. (2026). Extensive antagonistic variants across the human genome. Nature Communications, 17 (1) 6122, 1-12. doi: 10.1038/s41467-026-71215-3 |
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2026 Journal Article Poor mood after oral contraceptive use is associated with increased vulnerability to peripartum depression, premenstrual dysphoric disorder, and higher genetic risk for depressionKiewa, Jacqueline, Lind, Penelope A., Hickie, Ian B., Medland, Sarah E., Mitchell, Brittany E., Middeldorp, Christel M., Martin, Nicholas G., Wray, Naomi R. and Byrne, Enda M. (2026). Poor mood after oral contraceptive use is associated with increased vulnerability to peripartum depression, premenstrual dysphoric disorder, and higher genetic risk for depression. Archives of Womens Mental Health, 29 (3) 71, 1-13. doi: 10.1007/s00737-026-01708-z |
