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2025 Journal Article Body fluid biomarkers and psychosis risk in The Accelerating Medicines Partnership® Schizophrenia Program: design considerationsPerkins, Diana O., Jeffries, Clark D., Clark, Scott R., Upthegrove, Rachel, Wannan, Cassandra M. J., Wray, Naomi R., Li, Qingqin S., Do, Kim Q., Walker, Elaine, Paul Amminger, G., Anticevic, Alan, Cotter, David, Ellman, Lauren M., Mongan, David, Phassouliotis, Christina, Barbee, Jenna, Roth, Sharin, Billah, Tashrif, Corcoran, Cheryl, Calkins, Monica E., Cerrato, Felecia, Khadimallah, Ines, Klauser, Paul, Winter-van Rossum, Inge, Nunez, Angela R., Bleggi, Rachel S., Martin, Alicia R., Bouix, Sylvain, Pasternak, Ofer ... Woods, Scott W. (2025). Body fluid biomarkers and psychosis risk in The Accelerating Medicines Partnership® Schizophrenia Program: design considerations. Schizophrenia, 11 (1) 78, 78. doi: 10.1038/s41537-025-00610-4 |
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2025 Journal Article Caffeine consumption, psychological distress, and insomnia in a cohort of individuals with depressionMcIntosh, Harry A., Borgas, Aleah J., Aouira, Nisreen, Mitchell, Brittany L., Crouse, Jacob J., Medland, Sarah E., Hickie, Ian B., Wray, Naomi R., Martin, Nicholas G., Middeldorp, Christel M. and Byrne, Enda M. (2025). Caffeine consumption, psychological distress, and insomnia in a cohort of individuals with depression. Complex Psychiatry, 11 (1), 37-49. doi: 10.1159/000545393 |
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2025 Journal Article Ten years preceding a diagnosis of neurodegenerative disease in Europe and Australia: medication use, health conditions, and biomarkers associated with Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosisWei, Dang, Freydenzon, Anna, Guinebretiere, Octave, Zaidi, Karim, Yang, Fen, Ye, Weimin, Hammar, Niklas, Modig, Karin, Wray, Naomi R., Feychting, Maria, Hamieh, Nadine, Ventelou, Bruno, Lekens, Beranger, Gantzer, Laurene, Durrleman, Stanley, McRae, Allan, Couvy-Duchesne, Baptiste, Fang, Fang and Nedelec, Thomas (2025). Ten years preceding a diagnosis of neurodegenerative disease in Europe and Australia: medication use, health conditions, and biomarkers associated with Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. eBioMedicine, 113 105585, 1-13. doi: 10.1016/j.ebiom.2025.105585 |
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2025 Journal Article Improving Outcomes in Mental Health (IOMH)—an Australian longitudinal clinical study of families with children with neurodevelopmental problems: cohort profileGalligan, Dana E, Payne, Leanne, Sullivan, Daniel P., Bhadravathi Lokeshappa, Madhura, Ziser, Laura, Nunn, Lorelle, Wallace, Leanne M., Andersen, Isabella, Howarth, Sophie, Kato, Akina, Karunanithi, Mohan, Mingin, Cassandra, O’Scanaill, Sally, Aouira, Nisreen, Paramecwari, Ayu, Sanders, Matthew R., Cobham, Vanessa E., Wray, Naomi R., Henders, Anjali K., Byrne, Enda M., Heussler, Honey and Middeldorp, Christel M. (2025). Improving Outcomes in Mental Health (IOMH)—an Australian longitudinal clinical study of families with children with neurodevelopmental problems: cohort profile. BMJ Open, 15 (3) e091676, 1-12. doi: 10.1136/bmjopen-2024-091676 |
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2025 Journal Article Insights from a methylome-wide association study of antidepressant exposureDavyson, E., Shen, X., Huider, F., Adams, M. J., Borges, K., McCartney, D. L., Barker, L. F., van Dongen, J., Boomsma, D. I., Weihs, A., Grabe, H. J., Kühn, L., Teumer, A., Völzke, H., Zhu, T., Kaprio, J., Ollikainen, M., David, F. S., Meinert, S., Stein, F., Forstner, A. J., Dannlowski, U., Kircher, T., Tapuc, A., Czamara, D., Binder, E. B., Brückl, T., Kwong, A. S. F., Yousefi, P. ... McIntosh, A. M. (2025). Insights from a methylome-wide association study of antidepressant exposure. Nature Communications, 16 (1) 1908, 1908. doi: 10.1038/s41467-024-55356-x |
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2025 Journal Article Mental health and sleep correlates of self-reported outdoor daylight exposure in over 13,000 adults with depressionCrouse, Jacob J., Park, Shin Ho, Mitchell, Brittany L., Byrne, Enda M., Medland, Sarah E., Lin, Tian, Scott, Jan, de Haan, Zsofi, Tonini, Emiliana, Iorfino, Frank, Wray, Naomi R., Martin, Nicholas G. and Hickie, Ian B. (2025). Mental health and sleep correlates of self-reported outdoor daylight exposure in over 13,000 adults with depression. European Psychiatry, 68 (1) e41, 1-9. doi: 10.1192/j.eurpsy.2025.20 |
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2025 Journal Article Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapiesAdams, Mark J., Streit, Fabian, Meng, Xiangrui, Awasthi, Swapnil, Adey, Brett N., Choi, Karmel W., Chundru, V. Kartik, Coleman, Jonathan R.I., Ferwerda, Bart, Foo, Jerome C., Gerring, Zachary F., Giannakopoulou, Olga, Gupta, Priya, Hall, Alisha S.M., Harder, Arvid, Howard, David M., Hübel, Christopher, Kwong, Alex S.F., Levey, Daniel F., Mitchell, Brittany L. (Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium member), Ni, Guiyan, Ota, Vanessa K., Pain, Oliver, Pathak, Gita A., Schulte, Eva C., Shen, Xueyi, Thorp, Jackson G., Walker, Alicia, Yao, Shuyang ... McIntosh, Andrew M. (2025). Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies. Cell, 188 (3), 640-652.e9. doi: 10.1016/j.cell.2024.12.002 |
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2025 Journal Article Grey‐matter structure markers of Alzheimer's disease, Alzheimer's conversion, functioning and cognition: a meta‐analysis across 11 CohortsCouvy‐Duchesne, Baptiste, Frouin, Vincent, Bouteloup, Vincent, Koussis, Nikitas, Sidorenko, Julia, Jiang, Jiyang, Wink, Alle Meije, Lorenzini, Luigi, Barkhof, Frederik, Trollor, Julian N., Mangin, Jean‐François, Sachdev, Perminder S., Brodaty, Henry, Lupton, Michelle K., Breakspear, Michael, Colliot, Olivier, Visscher, Peter M., Wray, Naomi R., for the Alzheimer's Disease Neuroimaging Initiative, the Australian Imaging Biomarkers and Lifestyle flagship study of ageing, the Alzheimer's Disease Repository Without Borders Investigators and the MEMENTO cohort Study Group (2025). Grey‐matter structure markers of Alzheimer's disease, Alzheimer's conversion, functioning and cognition: a meta‐analysis across 11 Cohorts. Human Brain Mapping, 46 (2) e70089, 1-21. doi: 10.1002/hbm.70089 |
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2025 Journal Article Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivityYao, Shuyang, Harder, Arvid, Darki, Fahimeh, Chang, Yu-Wei, Li, Ang, Nikouei, Kasra, Volpe, Giovanni, Lundström, Johan N., Zeng, Jian, Wray, Naomi R., Lu, Yi, Sullivan, Patrick F. and Hjerling-Leffler, Jens (2025). Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity. Nature Communications, 16 (1) 395, 1-18. doi: 10.1038/s41467-024-55611-1 |
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2025 Journal Article Genome-wide copy number variation association study in anorexia nervosaWalker, Alicia, Karlsson, Robert, Szatkiewicz, Jin P., Thornton, Laura M., Yilmaz, Zeynep, Leppä, Virpi M., Savva, Androula, Lin, Tian, Sidorenko, Julia, McRae, Allan, Kirov, George, Davies, Helena L., Fundín, Bengt T., Chawner, Samuel J. R. A., Song, Jie, Borg, Stina, Wen, Jia, Watson, Hunna J., Munn-Chernoff, Melissa A., Baker, Jessica H., Gordon, Scott, Berrettini, Wade H., Brandt, Harry, Crawford, Steven, Halmi, Katherine A., Kaplan, Allan S., Kaye, Walter H., Mitchell, James, Strober, Michael ... Wray, Naomi R. (2025). Genome-wide copy number variation association study in anorexia nervosa. Molecular Psychiatry, 30 (5) 867, 2009-2016. doi: 10.1038/s41380-024-02811-2 |
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2025 Journal Article Familial coaggregation and shared familiality of functional and internalizing disorders in the Lifelines cohortBos, Martje, Monden, Rei, Wray, Naomi R., Zhou, Yiling, Kendler, Kenneth S., Rosmalen, Judith G. M., van Loo, Hanna M. and Snieder, Harold (2025). Familial coaggregation and shared familiality of functional and internalizing disorders in the Lifelines cohort. Psychological Medicine, 55 e126, e126-55. doi: 10.1017/s003329172500100x |
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2024 Journal Article Distinct genetic liability profiles define clinically relevant patient strata across common diseasesTrastulla, Lucia, Dolgalev, Georgii, Moser, Sylvain, Jiménez-Barrón, Laura T., Andlauer, Till F. M., von Scheidt, Moritz, Ruderfer, Douglas M., Ripke, Stephan, McQuillin, Andrew, Stahl, Eli A., Domenici, Enrico, Adolfsson, Rolf, Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Bacanu, Silviu A., Begemann, Martin, Belliveau, Richard A., Bene, Judit, Bergen, Sarah E., Bevilacqua, Elizabeth, Bigdeli, Tim B., Black, Donald W., Blackwood, Douglas H. R., Borglum, Anders D., Bramon, Elvira, Bruggeman, Richard ... Ziller, Michael J. (2024). Distinct genetic liability profiles define clinically relevant patient strata across common diseases. Nature Communications, 15 (1) 5534, 1-28. doi: 10.1038/s41467-024-49338-2 |
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2024 Journal Article Sex-specific association between genetic risk of psychiatric disorders and cardiovascular diseasesJiang, Jiayue-Clara, Singh, Kritika, Nitin, Rachana, Davis, Lea K., Wray, Naomi R. and Shah, Sonia (2024). Sex-specific association between genetic risk of psychiatric disorders and cardiovascular diseases. Circulation: Genomic and Precision Medicine, 17 (6) e004685, 1-12. doi: 10.1161/circgen.124.004685 |
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2024 Journal Article Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohortsAdams, Mark J., Thorp, Jackson G., Jermy, Bradley S., Kwong, Alex S. F., Kõiv, Kadri, Grotzinger, Andrew D., Nivard, Michel G., Marshall, Sally, Milaneschi, Yuri, Baune, Bernhard T., Müller-Myhsok, Bertram, Penninx, Brenda W. J. H., Boomsma, Dorret I., Levinson, Douglas F., Breen, Gerome, Pistis, Giorgio, Grabe, Hans J., Tiemeier, Henning, Berger, Klaus, Rietschel, Marcella, Magnusson, Patrik K., Uher, Rudolf, Hamilton, Steven P., Lucae, Susanne, Lehto, Kelli, Li, Qingqin S., Byrne, Enda M., Hickie, Ian B., Martin, Nicholas G. ... Derks, Eske M. (2024). Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts. Psychological Medicine, 54 (12), 3459-3468. doi: 10.1017/s0033291724001880 |
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2024 Journal Article Patterns of stressful life events and polygenic scores for five mental disorders and neuroticism among adults with depressionCrouse, Jacob J., Park, Shin Ho, Byrne, Enda M., Mitchell, Brittany L., Scott, Jan, Medland, Sarah E., Lin, Tian, Wray, Naomi R., Martin, Nicholas G. and Hickie, Ian B. (2024). Patterns of stressful life events and polygenic scores for five mental disorders and neuroticism among adults with depression. Molecular Psychiatry, 29 (9), 2765-2773. doi: 10.1038/s41380-024-02492-x |
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2024 Journal Article Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohortsAdams, Mark J., Thorp, Jackson G., Jermy, Bradley S., Kwong, Alex S. F., Koiv, Kadri, Grotzinger, Andrew D., Nivard, Michel G., Marshall, Sally, Milaneschi, Yuri, Baune, Bernhard T., Mueller-Myhsok, Bertram, Penninx, Brenda W. J. H., Boomsma, Dorret I., Levinson, Douglas F., Breen, Gerome, Pistis, Giorgio, Grabe, Hans J., Tiemeier, Henning, Berger, Klaus, Rietschel, Marcella, Magnusson, Patrik K., Uher, Rudolf, Hamilton, Steven P., Lucae, Susanne, Lehto, Kelli, Li, Qingqin S., Byrne, Enda M., Hickie, Ian B., Martin, Nicholas G. ... Derks, Eske M. (2024). Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts. Psychological Medicine, 54 (12), 3459-3468. doi: 10.1017/S0033291724001880 |
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2024 Journal Article R2ROC: an efficient method of comparing two or more correlated AUC from out-of-sample prediction using polygenic scoresMomin, Md. Moksedul, Wray, Naomi R. and Lee, S. Hong (2024). R2ROC: an efficient method of comparing two or more correlated AUC from out-of-sample prediction using polygenic scores. Human Genetics, 143 (9-10), 1193-1205. doi: 10.1007/s00439-024-02682-1 |
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2024 Journal Article Exercise rejuvenates microglia and reverses T cell accumulation in the aged female mouse brainChauquet, Solal, Willis, Emily F., Grice, Laura, Harley, Samuel B. R., Powell, Joseph E., Wray, Naomi R., Nguyen, Quan, Ruitenberg, Marc J., Shah, Sonia and Vukovic, Jana (2024). Exercise rejuvenates microglia and reverses T cell accumulation in the aged female mouse brain. Aging Cell, 23 (7) e14172, e14172. doi: 10.1111/acel.14172 |
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2024 Journal Article Genetic influence on within-person longitudinal change in anthropometric traits in the UK BiobankKemper, Kathryn E., Sidorenko, Julia, Wang, Huanwei, Hayes, Ben J., Wray, Naomi R., Yengo, Loic, Keller, Matthew C., Goddard, Michael and Visscher, Peter M. (2024). Genetic influence on within-person longitudinal change in anthropometric traits in the UK Biobank. Nature Communications, 15 (1) 3776, 3776. doi: 10.1038/s41467-024-47802-7 |
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2024 Journal Article Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestriesZheng, Zhili, Liu, Shouye, Sidorenko, Julia, Wang, Ying, Lin, Tian, Yengo, Loic, Turley, Patrick, Ani, Alireza, Wang, Rujia, Nolte, Ilja M., Snieder, Harold, Aguirre-Gamboa, Raul, Deelen, Patrick, Franke, Lude, Kuivenhoven, Jan A., Lopera Maya, Esteban A., Sanna, Serena, Swertz, Morris A., Vonk, Judith M., Wijmenga, Cisca, Yang, Jian, Wray, Naomi R., Goddard, Michael E., Visscher, Peter M., Zeng, Jian and LifeLines Cohort Study (2024). Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries. Nature Genetics, 56 (5), 1-11. doi: 10.1038/s41588-024-01704-y |
