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2023

Other Outputs

Skeletal muscle and blood RNA-seq counts in motor neurone disease cases and controls

Anna Freydenzon, Allan F. McRaee, Shyuan Ngo, Naomi R. Wray, Leanne Wallace, Anjali K. Henders, Pamela A. McCombe, Robert D. Henderson and Frederik J. Steyn (2023). Skeletal muscle and blood RNA-seq counts in motor neurone disease cases and controls. The University of Queensland. (Dataset) doi: 10.48610/b722f1f

Skeletal muscle and blood RNA-seq counts in motor neurone disease cases and controls

2021

Other Outputs

Lifetime Prevalence and Risk Factors for Perinatal Depression in a Large Cohort of Women with Depression

Kiewa, Jacqueline, Meltzer-Brody, Samantha, Milgrom, Jeanette, Bennett, Elizabeth, Mackle, Tracey, Guintivano, Jerry, Hickie, Ian B, Colodro-Conde, Lucía, Medland, Sarah, Martin, Nicholas G, Wray, Naomi R and Byrne, Enda M (2021). Lifetime Prevalence and Risk Factors for Perinatal Depression in a Large Cohort of Women with Depression. doi: 10.21203/rs.3.rs-362347/v2

Lifetime Prevalence and Risk Factors for Perinatal Depression in a Large Cohort of Women with Depression

2021

Other Outputs

Understanding genetic risk factors for common side effects of antidepressant medications

Campos, Adrian I., Mulcahy, Aoibhe, Thorp, Jackson G., Wray, Naomi R., Byrne, Enda M., Lind, Penelope A., Medland, Sarah E., Martin, Nicholas G., Hickie, Ian B. and Rentería, Miguel E. (2021). Understanding genetic risk factors for common side effects of antidepressant medications. doi: 10.1101/2021.07.12.21260397

Understanding genetic risk factors for common side effects of antidepressant medications

2021

Other Outputs

Methylome-wide association study of early life stressors and adult mental health reveals a relationship between birth date and cell type composition in blood

Howard, David M., Pain, Oliver, Arathimos, Ryan, Barbu, Miruna C., Amador, Carmen, Walker, Rosie M., Jermy, Bradley, Adams, Mark J., Deary, Ian J., Porteous, David, Campbell, Archie, Sullivan, Patrick F., Evans, Kathryn L., Arseneault, Louise, Wray, Naomi R., Meaney, Michael, McIntosh, Andrew M. and Lewis, Cathryn M. (2021). Methylome-wide association study of early life stressors and adult mental health reveals a relationship between birth date and cell type composition in blood. doi: 10.1101/2021.03.10.21253201

Methylome-wide association study of early life stressors and adult mental health reveals a relationship between birth date and cell type composition in blood

2020

Other Outputs

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

Mullins, Niamh, Kang, Jooeun, Campos, Adrian I, Coleman, Jonathan R I, Edwards, Alexis C, Galfalvy, Hanga, Levey, Daniel F, Lori, Adriana, Shabalin, Andrey, Starnawska, Anna, Su, Mei-Hsin, Watson, Hunna J, Adams, Mark, Awasthi, Swapnil, Gandal, Michael, Hafferty, Jonathan D, Hishimoto, Akitoyo, Kim, Minsoo, Okazaki, Satoshi, Otsuka, Ikuo, Ripke, Stephan, Ware, Erin B, Bergen, Andrew W, Berrettini, Wade H, Bohus, Martin, Brandt, Harry, Chang, Xiao, Chen, Wei J, Chen, Hsi-Chung ... Ruderfer, Douglas M (2020). Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors. doi: 10.1101/2020.12.01.20241281

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

2020

Other Outputs

Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction

Albiñana, Clara, Grove, Jakob, McGrath, John J., Agerbo, Esben, Wray, Naomi R., Werge, Thomas, Børglum, Anders D., Mortensen, Preben Bo, Privé, Florian and Vilhjálmsson, Bjarni J. (2020). Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction. doi: 10.1101/2020.11.27.401141

Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction

2020

Other Outputs

Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

Mullins, Niamh, Forstner, Andreas J., O’Connell, Kevin S., Coombes, Brandon, Coleman, Jonathan R. I., Qiao, Zhen, Als, Thomas D., Bigdeli, Tim B., Børte, Sigrid, Bryois, Julien, Charney, Alexander W., Drange, Ole Kristian, Gandal, Michael J., Hagenaars, Saskia P., Ikeda, Masashi, Kamitaki, Nolan, Kim, Minsoo, Krebs, Kristi, Panagiotaropoulou, Georgia, Schilder, Brian M., Sloofman, Laura G., Steinberg, Stacy, Trubetskoy, Vassily, Winsvold, Bendik S., Won, Hong-Hee, Abramova, Liliya, Adorjan, Kristina, Agerbo, Esben, Al Eissa, Mariam ... Andreassen, Ole A. (2020). Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology. doi: 10.1101/2020.09.17.20187054

Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

2020

Other Outputs

A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts

Ni, Guiyan, Zeng, Jian, Revez, Joana A, Wang, Ying, Zheng, Zhili, Ge, Tian, Restuadi, Restuadi, Kiewa, Jacqueline, Nyholt, Dale R, Coleman, Jonathan R I, Smoller, Jordan W, Consortium, Schizophrenia Working Group of the Psychiatric Genomics, Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics, Yang, Jian, Visscher, Peter M and Wray, Naomi R (2020). A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts. doi: 10.1101/2020.09.10.20192310

A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts

2020

Other Outputs

Genome-wide analyses of behavioural traits biased by misreports and longitudinal changes

Xue, Angli, Jiang, Longda, Zhu, Zhihong, Wray, Naomi R., Visscher, Peter M., Zeng, Jian and Yang, Jian (2020). Genome-wide analyses of behavioural traits biased by misreports and longitudinal changes. doi: 10.1101/2020.06.15.20131284

Genome-wide analyses of behavioural traits biased by misreports and longitudinal changes

2020

Other Outputs

Comorbid chronic pain and depression: Shared risk factors and differential antidepressant effectiveness

Roughan, William H., Campos, Adrián I., García-Marín, Luis M., Cuéllar-Partida, Gabriel, Lupton, Michelle K., Hickie, Ian B., Medland, Sarah E., Wray, Naomi R., Byrne, Enda M., Ngo, Trung Thanh, Martin, Nicholas G. and Rentería, Miguel E. (2020). Comorbid chronic pain and depression: Shared risk factors and differential antidepressant effectiveness. doi: 10.1101/2020.05.23.20110841

Comorbid chronic pain and depression: Shared risk factors and differential antidepressant effectiveness

2020

Other Outputs

Investigating the potential effect of antihypertensive medication on psychiatric disorders: a mendelian randomisation study

Chauquet, Solal, O’Donovan, Michael, Walters, James, Wray, Naomi and Shah, Sonia (2020). Investigating the potential effect of antihypertensive medication on psychiatric disorders: a mendelian randomisation study. doi: 10.1101/2020.03.19.20039412

Investigating the potential effect of antihypertensive medication on psychiatric disorders: a mendelian randomisation study

2019

Other Outputs

Genetic comorbidity between major depression and cardio-metabolic disease, stratified by age at onset of major depression

Hagenaars, SP, Coleman, JRI, Choi, S, Gaspar, H, Adams, MJ, Howard, D, Hodgson, K, Traylor, M, Air, TM, Andlauer, TFM, Arolt, V, Baune, BT, Binder, EB, Blackwood, DHR, Boomsma, DI, Campbell, A, Cearns, M, Czamara, D, Dannlowski, U, Domschke, K, de Geus, EJC, Hamilton, SP, Hayward, C, Hickie, I, Hottenga, JJ, Ising, M, Jones, I, Jones, LA, Kutalik, Z ... Lewis, CM (2019). Genetic comorbidity between major depression and cardio-metabolic disease, stratified by age at onset of major depression. doi: 10.1101/645077

Genetic comorbidity between major depression and cardio-metabolic disease, stratified by age at onset of major depression

2019

Other Outputs

The Australian Genetics of Depression Study: Study Description and Sample Characteristics

Byrne, Enda M, Kirk, Katherine M, Medland, Sarah E, McGrath, John J, Parker, Richard, Cross, Simone, Sullivan, Lenore, Statham, Dixie J, Levinson, Douglas F, Licinio, Julio, Wray, Naomi R, Hickie, Ian B and Martin, Nicholas G (2019). The Australian Genetics of Depression Study: Study Description and Sample Characteristics. doi: 10.1101/626762

The Australian Genetics of Depression Study: Study Description and Sample Characteristics

2019

Other Outputs

Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

Byrne, Enda M, Zhu, Zhihong, Qi, Ting, Skene, Nathan G, Bryois, Julien, Pardinas, Antonio F, Stahl, Eli, Smoller, Jordan W, Rietschel, Marcella, Consortium, Bipolar Working Group of the Psychiatric Genomics, Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics, Owen, Michael J, Walters, James T.R., O’Donovan, Michael C, McGrath, John G, Hjerling-Leffler, Jens, Sullivan, Patrick F, Goddard, Michael E, Visscher, Peter M, Yang, Jian and Wray, Naomi R (2019). Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders. doi: 10.1101/592899

Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

2019

Other Outputs

Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936

Hillary, Robert F., McCartney, Daniel L., Harris, Sarah E., Stevenson, Anna J., Seeboth, Anne, Zhang, Qian, Liewald, David C., Evans, Kathryn L., Ritchie, Craig W., Tucker-Drob, Elliot M., Wray, Naomi R., McRae, Allan F., Visscher, Peter M., Deary, Ian J. and Marioni, Riccardo E. (2019). Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936. doi: 10.1101/558940

Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936

2019

Other Outputs

Improved polygenic prediction by Bayesian multiple regression on summary statistics

Lloyd-Jones, Luke R., Zeng, Jian, Sidorenko, Julia, Yengo, Loïc, Moser, Gerhard, Kemper, Kathryn E., Wang, Huanwei, Zheng, Zhili, Magi, Reedik, Esko, Tonu, Metspalu, Andres, Wray, Naomi R., Goddard, Michael E., Yang, Jian and Visscher, Peter M. (2019). Improved polygenic prediction by Bayesian multiple regression on summary statistics. doi: 10.1101/522961

Improved polygenic prediction by Bayesian multiple regression on summary statistics

2018

Other Outputs

Genetic analyses of medication-use and implications for precision medicine

Wu, Yeda, Byrne, Enda M., Zheng, Zhili, Kemper, Kathryn E., Yengo, Loic, Mallett, Andrew J., Yang, Jian, Visscher, Peter M. and Wray, Naomi R. (2018). Genetic analyses of medication-use and implications for precision medicine. doi: 10.1101/501049

Genetic analyses of medication-use and implications for precision medicine

2018

Other Outputs

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

Howard, David M., Adams, Mark J., Clarke, Toni-Kim, Hafferty, Jonathan D., Gibson, Jude, Shirali, Masoud, Coleman, Jonathan R. I., Hagenaars, Saskia P., Ward, Joey, Wigmore, Eleanor M., Alloza, Clara, Shen, Xueyi, Barbu, Miruna C., Xu, Eileen Y., Whalley, Heather C., Marioni, Riccardo E., Porteous, David J., Davies, Gail, Deary, Ian J., Hemani, Gibran, Berger, Klaus, Teismann, Henning, Rawal, Rajesh, Arolt, Volker, Baune, Bernhard T., Dannlowski, Udo, Domschke, Katharina, Tian, Chao, Hinds, David A. ... McIntosh, Andrew M. (2018). Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. doi: 10.1101/433367

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

2018

Other Outputs

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

Mullins, Niamh, Bigdeli, Tim B., Børglum, Anders D, Coleman, Jonathan R I, Demontis, Ditte, Fanous, Ayman H., Mehta, Divya, Power, Robert A., Ripke, Stephan, Stahl, Eli A, Starnawska, Anna, Anjorin, Adebayo, Corvin, Aiden, Sanders, Alan R, Forstner, Andreas J, Reif, Andreas, Koller, Anna C, Świątkowska, Beata, Baune, Bernhard T, Müller-Myhsok, Bertram, Konte, Bettina, Penninx, Brenda WJH, Pato, Carlos, Zai, Clement, Rujescu, Dan, Quested, Digby, Levinson, Douglas F, Binder, Elisabeth B, Byrne, Enda M ... Lewis, Cathryn M (2018). Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores. doi: 10.1101/416008

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

2018

Other Outputs

Evidence of causal effect of major depression on alcohol dependence: Findings from the Psychiatric Genomics Consortium

Polimanti, Renato, Peterson, Roseann E., Ong, Jue-Sheng, MacGregor, Stuart, Edwards, Alexis C., Clarke, Toni-Kim, Frank, Josef, Gerring, Zachary, Gillespie, Nathan A., Lind, Penelope A., Maes, Hermine H., Martin, Nicholas G., Mbarek, Hamdi, Medland, Sarah E., Streit, Fabian, Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics, Consortium, Substance Use Disorder Working Group of the Psychiatric Genomics, Team, 23andMe Research, Agrawal, Arpana, Edenberg, Howard J., Kendler, Kenneth S., Lewis, Cathryn M., Sullivan, Patrick F., Wray, Naomi R., Gelernter, Joel and Derks, Eske M. (2018). Evidence of causal effect of major depression on alcohol dependence: Findings from the Psychiatric Genomics Consortium. doi: 10.1101/412098

Evidence of causal effect of major depression on alcohol dependence: Findings from the Psychiatric Genomics Consortium