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2018

Other Outputs

Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell counts and epigenetic ageing

Stevenson, Anna J, McCartney, Daniel L, Harris, Sarah E, Taylor, Adele M, Redmond, Paul, Starr, John M, Zhang, Qian, McRae, Allan F, Wray, Naomi R, Spires-Jones, Tara L, McColl, Barry W, McIntosh, Andrew M, Deary, Ian J and Marioni, Riccardo E (2018). Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell counts and epigenetic ageing. doi: 10.1101/397877

Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell counts and epigenetic ageing

2018

Other Outputs

Epigenetic prediction of complex traits and death

McCartney, Daniel L, Stevenson, Anna J, Ritchie, Stuart J, Walker, Rosie M, Zhang, Qian, Morris, Stewart W, Campbell, Archie, Murray, Alison D, Whalley, Heather C, Gale, Catharine R, Porteous, David J, Haley, Chris S, McRae, Allan F, Wray, Naomi R, Visscher, Peter M, McIntosh, Andrew M, Evans, Kathryn L, Deary, Ian J and Marioni, Riccardo E (2018). Epigenetic prediction of complex traits and death. doi: 10.1101/294116

Epigenetic prediction of complex traits and death

2018

Other Outputs

GWAS on family history of Alzheimer’s disease

Marioni, Riccardo E., Harris, Sarah E., McRae, Allan F., Zhang, Qian, Hagenaars, Saskia P., Hill, W. David, Davies, Gail, Ritchie, Craig W., Gale, Catharine, Starr, John M., Goate, Alison M., Porteous, David J., Yang, Jian, Evans, Kathryn L., Deary, Ian J., Wray, Naomi R. and Visscher, Peter M. (2018). GWAS on family history of Alzheimer’s disease. doi: 10.1101/246223

GWAS on family history of Alzheimer’s disease

2018

Other Outputs

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Coleman, Jonathan R.I., Peyrot, Wouter J., Purves, Kirstin L., Davis, Katrina A.S., Rayner, Christopher, Choi, Shing Wan, Hübel, Christopher, Gaspar, Héléna A., Kan, Carol, Van der Auwera, Sandra, Adams, Mark James, Lyall, Donald M., Choi, Karmel W., Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics, Dunn, Erin C., Vassos, Evangelos, Danese, Andrea, Maughan, Barbara, Grabe, Hans J., Lewis, Cathryn M., O’Reilly, Paul F., McIntosh, Andrew M., Smith, Daniel J., Wray, Naomi R., Hotopf, Matthew, Eley, Thalia C. and Breen, Gerome (2018). Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. doi: 10.1101/247353

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

2017

Other Outputs

Age at first birth in women is genetically associated with increased risk of schizophrenia

Ni, Guiyan, Gratten, Jacob, Consortium, Schizophrenia Working Group of the Psychiatric Genomics, Wray, Naomi R. and Lee, S. Hong (2017). Age at first birth in women is genetically associated with increased risk of schizophrenia. doi: 10.1101/194076

Age at first birth in women is genetically associated with increased risk of schizophrenia

2017

Other Outputs

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

Ruderfer, Douglas M, Ripke, Stephan, McQuillin, Andrew, Boocock, James, Stahl, Eli A, Pavlides, Jennifer M Whitehead, Mullins, Niamh, Charney, Alexander W, Ori, Anil P S, Loohuis, Loes M Olde, Domenici, Enrico, Di Florio, Arianna, Papiol, Sergi, Kalman, Janos L., Adolfsson, Rolf, Agartz, Ingrid, Agerbo, Esben, Akil, Huda, Albani, Diego, Albus, Margot, Alda, Martin, Alexander, Madeline, Allardyce, Judith, Alliey-Rodriguez, Ney, Als, Thomas D, Amin, Farooq, Anjorin, Adebayo, Arranz, Maria J, Awasthi, Swapnil ... Kendler, Kenneth S (2017). Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes. doi: 10.1101/173435

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

2017

Other Outputs

Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder

Stahl, Eli A, Breen, Gerome, Forstner, Andreas J, McQuillin, Andrew, Ripke, Stephan, Trubetskoy, Vassily, Mattheisen, Manuel, Wang, Yunpeng, Coleman, Jonathan R I, Gaspar, Héléna A, de Leeuw, Christiaan A, Steinberg, Stacy, Pavlides, Jennifer M Whitehead, Trzaskowski, Maciej, Pers, Tune H, Holmans, Peter A, Abbott, Liam, Agerbo, Esben, Akil, Huda, Albani, Diego, Alliey-Rodriguez, Ney, Als, Thomas D, Anjorin, Adebayo, Antilla, Verneri, Awasthi, Swapnil, Badner, Judith A, Bækvad-Hansen, Marie, Barchas, Jack D, Bass, Nicholas ... Sklar, Pamela (2017). Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder. doi: 10.1101/173062

Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder

2017

Other Outputs

Causal associations between risk factors and common diseases inferred from GWAS summary data

Zhu, Zhihong, Zheng, Zhili, Zhang, Futao, Wu, Yang, Trzaskowski, Maciej, Maier, Robert, Robinson, Matthew R., McGrath, John J., Visscher, Peter M., Wray, Naomi R. and Yang, Jian (2017). Causal associations between risk factors and common diseases inferred from GWAS summary data. doi: 10.1101/168674

Causal associations between risk factors and common diseases inferred from GWAS summary data

2017

Other Outputs

Widespread signatures of negative selection in the genetic architecture of human complex traits

Zeng, Jian, de Vlaming, Ronald, Wu, Yang, Robinson, Matthew R, Lloyd-Jones, Luke, Yengo, Loic, Yap, Chloe, Xue, Angli, Sidorenko, Julia, McRae, Allan F, Powell, Joseph E, Montgomery, Grant W, Metspalu, Andres, Esko, Tonu, Gibson, Greg, Wray, Naomi R, Visscher, Peter M and Yang, Jian (2017). Widespread signatures of negative selection in the genetic architecture of human complex traits. doi: 10.1101/145755

Widespread signatures of negative selection in the genetic architecture of human complex traits

2017

Other Outputs

Genetic stratification of depression in UK Biobank suggests a subgroup linked to age of natural menopause

Howard, David M., Folkersen, Lasse, Coleman, Jonathan R. I., Adams, Mark J., Glanville, Kylie, Werge, Thomas, Hagenaars, Saskia P., Han, Buhm, Porteous, David, Campbell, Archie, Clarke, Toni-Kim, Breen, Gerome, Sullivan, Patrick F., Wray, Naomi R., Lewis, Cathryn M. and McIntosh, Andrew M. (2017). Genetic stratification of depression in UK Biobank suggests a subgroup linked to age of natural menopause. doi: 10.1101/134601

Genetic stratification of depression in UK Biobank suggests a subgroup linked to age of natural menopause

2016

Other Outputs

DEAR-O: Differential Expression Analysis based on RNA-seq data - Online

Zhang, Zong-Hong, Wray, Naomi R. and Zhao, Qiong-Yi (2016). DEAR-O: Differential Expression Analysis based on RNA-seq data - Online. doi: 10.1101/069807

DEAR-O: Differential Expression Analysis based on RNA-seq data - Online

2016

Other Outputs

Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection

Pardiñas, Antonio F., Holmans, Peter, Pocklington, Andrew J., Escott-Price, Valentina, Ripke, Stephan, Carrera, Noa, Legge, Sophie E., Bishop, Sophie, Cameron, Darren, Hamshere, Marian L., Han, Jun, Hubbard, Leon, Lynham, Amy, Mantripragada, Kiran, Rees, Elliott, MacCabe, James H., McCarroll, Steven A., Baune, Bernhard T., Breen, Gerome, Byrne, Enda M., Dannlowski, Udo, Eley, Thalia C., Hayward, Caroline, Martin, Nicholas G., McIntosh, Andrew M., Plomin, Robert, Porteous, David J., Wray, Naomi R., Consortium, GERAD ... Walters, James T. R. (2016). Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection. doi: 10.1101/068593

Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection

2016

Other Outputs

A better design for stratified medicine based on genomic prediction

Lee, S. Hong, Weerasinghe, W.M. Shalanee P., Wray, Naomi R., Goddard, Michael E. and Van der Werf, Julius H.J. (2016). A better design for stratified medicine based on genomic prediction. doi: 10.1101/054494

A better design for stratified medicine based on genomic prediction

2015

Other Outputs

Using genotype data to distinguish pleiotropy from heterogeneity: deciphering coheritability in autoimmune and neuropsychiatric diseases

Han, Buhm, Pouget, Jennie G, Slowikowski, Kamil, Stahl, Eli, Lee, Cue Hyunkyu, Diogo, Dorothee, Hu, Xinli, Park, Yu Rang, Kim, Eunji, Gregersen, Peter K, Dahlqvist, Solbritt Rantapää, Worthington, Jane, Martin, Javier, Eyre, Steve, Klareskog, Lars, Huizinga, Tom, Chen, Wei-Min, Onengut-Gumuscu, Suna, Rich, Stephen S, Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics, Wray, Naomi and Raychaudhuri, Soumya (2015). Using genotype data to distinguish pleiotropy from heterogeneity: deciphering coheritability in autoimmune and neuropsychiatric diseases. doi: 10.1101/030783

Using genotype data to distinguish pleiotropy from heterogeneity: deciphering coheritability in autoimmune and neuropsychiatric diseases