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2016 Journal Article Promiscuous metallo-β-lactamases: MIM-1 and MIM-2 may play an essential role in quorum sensing networksMiraula, Manfredi, Schenk, Gerhard and Mitic, Natasa (2016). Promiscuous metallo-β-lactamases: MIM-1 and MIM-2 may play an essential role in quorum sensing networks. Journal of Inorganic Biochemistry, 162, 366-375. doi: 10.1016/j.jinorgbio.2015.12.014 |
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2016 Journal Article Organophosphate-degrading metallohydrolases: structure and function of potent catalysts for applications in bioremediationSchenk, Gerhard, Mateen, Irsa, Ng, Tee-Kheang, Pedroso, Marcelo M., Mitic, Natasa, Jafelicci, Miguel, Marques, Rodrigo F. C., Gahan, Lawrence R. and Ollis, David L. (2016). Organophosphate-degrading metallohydrolases: structure and function of potent catalysts for applications in bioremediation. Coordination Chemistry Reviews, 317, 122-131. doi: 10.1016/j.ccr.2016.03.006 |
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2016 Journal Article Metal ions play an essential catalytic role in the mechanism of ketol-acid reductoisomeraseTadrowski, Sonya, Pedroso, Marcelo M., Sieber, Volker, Larrabee, James A., Guddat, Luke W. and Schenk, Gerhard (2016). Metal ions play an essential catalytic role in the mechanism of ketol-acid reductoisomerase. Chemistry, 22 (22), 7427-7436. doi: 10.1002/chem.201600620 |
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2016 Journal Article Design, synthesis, and in vitro and biological evaluation of potent amino acid-derived thiol inhibitors of the metallo-β-lactamase IMP-1Arjomandi, Omid Khalili, Hussein, Waleed M., Vella, Peter, Yusof, Yusralina, Sidjabat, Hanna E., Schenk, Gerhard and McGeary, Ross P. (2016). Design, synthesis, and in vitro and biological evaluation of potent amino acid-derived thiol inhibitors of the metallo-β-lactamase IMP-1. European Journal of Medicinal Chemistry, 114, 318-327. doi: 10.1016/j.ejmech.2016.03.017 |
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2016 Journal Article Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase at 1.0 Å resolution: A potential target for anti-tuberculosis drug discoveryYou, Lv, Kandale, Ajit, Wun, Shun Jie, McGeary, Ross P., Williams, Simon J., Kobe, Bostjan, Sieber, Volker, Schembri, Mark A., Schenk, Gerhard and Guddat, Luke W. (2016). Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase at 1.0 Å resolution: A potential target for anti-tuberculosis drug discovery. Febs Journal, 283 (7), 1184-1196. doi: 10.1111/febs.13672 |
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2016 Journal Article Investigation of the identity of the nucleophile initiating the hydrolysis of phosphate esters catalyzed by dinuclear mimics of metallohydrolasesBrown, Joshua J., Gahan, Lawrence R., Schöffler, Anne, Krenske, Elizabeth H. and Schenk, Gerhard (2016). Investigation of the identity of the nucleophile initiating the hydrolysis of phosphate esters catalyzed by dinuclear mimics of metallohydrolases. Journal of Inorganic Biochemistry, 162, 356-365. doi: 10.1016/j.jinorgbio.2016.02.008 |
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2016 Journal Article Captopril analogues as metallo-β-lactamase inhibitorsYusof, Yusralina, Tan, Daniel T. C., Arjomandi, Omid Khalili, Schenk, Gerhard and McGeary, Ross P. (2016). Captopril analogues as metallo-β-lactamase inhibitors. Bioorganic and Medicinal Chemistry Letters, 26 (6), 1589-1593. doi: 10.1016/j.bmcl.2016.02.007 |
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2016 Journal Article CaII binding regulates and dominates the reactivity of a transition-metal-ion-dependent diesterase from Mycobacterium tuberculosisPedroso, Marcelo M., Larrabee, James A., Ely, Fernanda, Gwee, Shuhui E., Mitic, Natasa, Ollis, David L., Gahan, Lawrence R. and Schenk, Gerhard (2016). CaII binding regulates and dominates the reactivity of a transition-metal-ion-dependent diesterase from Mycobacterium tuberculosis. Chemistry - A European Journal, 22 (3), 999-1009. doi: 10.1002/chem.201504001 |
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2016 Journal Article Asymmetric mono- and dinuclear GaIII and ZnII complexes as models for purple acid phosphatasesBosch, Simone, Comba, Peter, Gahan, Lawrence R. and Schenk, Gerhard (2016). Asymmetric mono- and dinuclear GaIII and ZnII complexes as models for purple acid phosphatases. Journal of Inorganic Biochemistry, 162, 343-355. doi: 10.1016/j.jinorgbio.2015.12.028 |
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2015 Journal Article Induction of apoptosis in leukemia cell lines by new copper(II) complexes containing naphthyl groups via interaction with death receptorsFernandes, Christiane, Horn Jr, Adolfo, Lopes, Bruna F., Bull, Erika S., Azeredo, Nathália F., Kanashiro, Milton M., Borges, Franz V., Bortoluzzi, Adailton J., Szpoganicz, Bruno, Pires, Anderson B., Franco, Roberto W. A., de A. Almeida, João Carlos, Maciel, Leide L. F., Resende, Jackson A. L. C. and Schenk, Gerhard (2015). Induction of apoptosis in leukemia cell lines by new copper(II) complexes containing naphthyl groups via interaction with death receptors. Journal of Inorganic Biochemistry, 153, 68-87. doi: 10.1016/j.jinorgbio.2015.09.014 |
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2015 Journal Article Heavy Water as a Probe of the Free Radical Nature and Electrical Conductivity of MelaninRienecker, Shermiyah B., Mostert, A. Bernardus, Schenk, Gerhard, Hanson, Graeme R. and Meredith, Paul (2015). Heavy Water as a Probe of the Free Radical Nature and Electrical Conductivity of Melanin. Journal of Physical Chemistry B, 119 (48), 14994-15000. doi: 10.1021/acs.jpcb.5b08970 |
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2015 Journal Article Selective coordination of gallium(III), zinc(II), and copper(II) by an asymmetric dinucleating ligand: a model for metallophosphatasesBosch, Simone, Comba, Peter, Gahan, Lawrence R., Hanson, Graeme R., Noble, Christopher, Schenk, Gerhard and Wadepohl, Hubert (2015). Selective coordination of gallium(III), zinc(II), and copper(II) by an asymmetric dinucleating ligand: a model for metallophosphatases. Chemistry - A European Journal, 21 (50), 18269-18279. doi: 10.1002/chem.201503348 |
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2015 Journal Article Use of magnetic circular dichroism to study dinuclear metallohydrolases and the corresponding biomimeticsLarrabee, James A., Schenk, Gerhard, Mitic, Natasa and Riley, Mark J. (2015). Use of magnetic circular dichroism to study dinuclear metallohydrolases and the corresponding biomimetics. European Biophysics Journal, 44 (6), 393-415. doi: 10.1007/s00249-015-1053-6 |
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2015 Journal Article An approach to more accurate model systems for purple acid phosphatases (PAPs)Bernhardt, Paul V., Bosch, Simone, Comba, Peter, Gahan, Lawrence R., Hanson, Graeme R., Mereacre, Valeriu, Noble, Christopher J., Powell, Annie K., Schenk, Gerhard and Wadepohl, Hubert (2015). An approach to more accurate model systems for purple acid phosphatases (PAPs). Inorganic Chemistry, 54 (15), 7249-7263. doi: 10.1021/acs.inorgchem.5b00628 |
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2015 Journal Article A Heterodinuclear Fe<sup>III</sup>Zn<sup>II</sup> Complex as a Mimic for Purple Acid Phosphatase with Site-Specific Zn<sup>II</sup> BindingRoberts, Asha E, Schenk, Gerhard and Gahan, Lawrence R (2015). A Heterodinuclear FeIIIZnII Complex as a Mimic for Purple Acid Phosphatase with Site-Specific ZnII Binding. European Journal of Inorganic Chemistry, 2015 (19), 3076-3086. doi: 10.1002/ejic.201500351 |
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2015 Journal Article Altering the substrate specificity of methyl parathion hydrolase with directed evolutionNg, Tee-Kheang, Gahan, Lawrence R., Schenk, Gerhard and Ollis, David L. (2015). Altering the substrate specificity of methyl parathion hydrolase with directed evolution. Archives of Biochemistry and Biophysics, 573, 59-68. doi: 10.1016/j.abb.2015.03.012. |
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2015 Journal Article Insight on the interaction of an agmatinase-like protein with Mn(2 +) activator ionsQuiñones, Matías, Cofre, Jaime, Benítez, José, García, David, Romero, Nicol, González, Arlette, Carvajal, Nelson, García, María, López, Vasthi, Schenk, Gerhard and Uribe, Elena (2015). Insight on the interaction of an agmatinase-like protein with Mn(2 +) activator ions. Journal of Inorganic Biochemistry, 145, 65-69. doi: 10.1016/j.jinorgbio.2015.01.008 |
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2015 Journal Article Inteins—A focus on the biotechnological applications of splicing-promoting proteinsMiraula, Manfredi, Enculescu, Charmaine, Schenk, Gerhard and Mitić, Nataša (2015). Inteins—A focus on the biotechnological applications of splicing-promoting proteins. American Journal of Molecular Biology, 05 (02), 42-56. doi: 10.4236/ajmb.2015.52005 |
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2015 Journal Article β-Lactam antibiotic-degrading enzymes from non-pathogenic marine organisms: a potential threat to human healthMiraula, Manfredi, Whitaker, Jacob J, Schenk, Gerhard and Mitic, Natasa (2015). β-Lactam antibiotic-degrading enzymes from non-pathogenic marine organisms: a potential threat to human health. Journal of Biological Inorganic Chemistry, 20 (4), 639-651. doi: 10.1007/s00775-015-1250-x |
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2015 Journal Article Iron, copper and manganese complexes with in vitro superoxide dismutase and/or catalase activities that keep Saccharomyces cerevisiae cells alive under severe oxidative stressRibeiro, Thales P., Fernandes, Christiane, Melo, Karen V., Ferreira, Sarah S., Lessa, Josane A., Franco, Roberto W A., Schenk, Gerhard, Pereira, Marcos D. and Horn, Adolfo (2015). Iron, copper and manganese complexes with in vitro superoxide dismutase and/or catalase activities that keep Saccharomyces cerevisiae cells alive under severe oxidative stress. Free Radical Biology and Medicine, 80, 67-76. doi: 10.1016/j.freeradbiomed.2014.12.005 |
