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2018

Journal Article

Evaluation of a bone morphogenetic protein 6 variant as a cause of iron loading

McDonald, Cameron J., Rishi, Gautam, Secondes, Eriza S., Ostini, Lesa, Wallace, Daniel F., Crawford, Darrell H. G., Sia, Hanlon, Clark, Paul and Subramaniam, V. Nathan (2018). Evaluation of a bone morphogenetic protein 6 variant as a cause of iron loading. Human Genomics, 12 (1) 23, 23. doi: 10.1186/s40246-018-0155-5

Evaluation of a bone morphogenetic protein 6 variant as a cause of iron loading

2018

Journal Article

Ferroportin expression in adipocytes does not contribute to iron homeostasis or metabolic responses to a high calorie diet

Britton, Laurence, Jaskowski, Lesley-Anne, Bridle, Kim, Secondes, Eriza, Wallace, Daniel, Santrampurwala, Nishreen, Reiling, Janske, Miller, Gregory, Mangiafico, Salvatore, Andrikopoulos, Sofianos, Subramaniam, V. Nathan and Crawford, Darrell (2018). Ferroportin expression in adipocytes does not contribute to iron homeostasis or metabolic responses to a high calorie diet. CMGH, 5 (3), 319-331. doi: 10.1016/j.jcmgh.2018.01.005

Ferroportin expression in adipocytes does not contribute to iron homeostasis or metabolic responses to a high calorie diet

2018

Journal Article

Reversal of end-stage heart failure in juvenile hemochromatosis with iron chelation therapy: a case report

Cooray, Shamil D., Heerasing, Neel M., Selkrig, Laura A., Subramaniam, V. Nathan, Hamblin, P. Shane, McDonald, Cameron J., McLean, Catriona A., McNamara, Elissa, Leet, Angeline S. and Roberts, Stuart K. (2018). Reversal of end-stage heart failure in juvenile hemochromatosis with iron chelation therapy: a case report. Journal of Medical Case Reports, 12 (1) 18. doi: 10.1186/s13256-017-1526-6

Reversal of end-stage heart failure in juvenile hemochromatosis with iron chelation therapy: a case report

2018

Journal Article

Iron inhibits the secretion of Apolipoprotein E in cultured human adipocytes

Britton, L. J., Bridle, Kim, Jaskowski, Lesley-Anne, He, Jingjing, Ng, Choaping, Ruelcke, Jayde E., Mohamed, Ahmed, Reiling, Janske, Santrampurwala, Nishreen, Hill, Michelle M., Whitehead, Jonathan P., Subramaniam, V. Nathan and Crawford, Darrell H. G. (2018). Iron inhibits the secretion of Apolipoprotein E in cultured human adipocytes. Cellular and Molecular Gastroenterology and Hepatology, 6 (2), 214-217. doi: 10.1016/j.jcmgh.2018.04.005

Iron inhibits the secretion of Apolipoprotein E in cultured human adipocytes

2017

Journal Article

The relationship between systemic iron homeostasis and erythropoiesis

Rishi, Gautam and Subramaniam, V. Nathan (2017). The relationship between systemic iron homeostasis and erythropoiesis. Bioscience Reports, 37 (6) BSR20170195, BSR20170195. doi: 10.1042/BSR20170195

The relationship between systemic iron homeostasis and erythropoiesis

2017

Journal Article

The dynamics of hepcidin-ferroportin internalization and consequences of a novel ferroportin disease mutation

Wallace, Daniel F., McDonald, Cameron J., Ostini, Lesa, Iser, David, Tuckfield, Annabel and Subramaniam, V. Nathan (2017). The dynamics of hepcidin-ferroportin internalization and consequences of a novel ferroportin disease mutation. American Journal of Hematology, 92 (10), 1052-1061. doi: 10.1002/ajh.24844

The dynamics of hepcidin-ferroportin internalization and consequences of a novel ferroportin disease mutation

2017

Journal Article

The liver in regulation of iron homeostasis

Rishi, Gautam and Subramaniam, V Nathan (2017). The liver in regulation of iron homeostasis. American Journal of Physiology - Gastrointestinal and Liver Physiology, 313 (3), G157-G165. doi: 10.1152/ajpgi.00004.2017

The liver in regulation of iron homeostasis

2017

Journal Article

Combination curcumin and vitamin E treatment attenuates diet-induced steatosis in Hfe-/- mice

Heritage, Mandy, Jaskowski, Lesley, Bridle, Kim, Campbell, Catherine, Briskey, David, Britton, Laurence, Fletcher, Linda, Vitetta, Luis, Subramaniam, V. Nathan and Crawford, Darrell (2017). Combination curcumin and vitamin E treatment attenuates diet-induced steatosis in Hfe-/- mice. World Journal of Gastrointestinal Pathophysiology, 8 (2), 67-76. doi: 10.4291/wjgp.v8.i2.67

Combination curcumin and vitamin E treatment attenuates diet-induced steatosis in Hfe-/- mice

2017

Journal Article

GNPAT p.D519G is independently associated with markedly increased iron stores in HFE p.C282Y homozygotes

Barton, James C., Chen, Wen-pin, Emond, Mary J., Phatak, Pradyumna D., Subramaniam, V. Nathan, Adams, Paul C., Gurrin, Lyle C., Anderson, Gregory J., Ramm, Grant A., Powell, Lawrie W., Allen, Katrina J., Phillips, John D., Parker, Charles J., McLaren, Gordon D. and McLaren, Christine E. (2017). GNPAT p.D519G is independently associated with markedly increased iron stores in HFE p.C282Y homozygotes. Blood Cells, Molecules and Diseases, 63, 15-20. doi: 10.1016/j.bcmd.2016.11.009

GNPAT p.D519G is independently associated with markedly increased iron stores in HFE p.C282Y homozygotes

2017

Journal Article

GNPAT Polymorphism rs11558492 Is Not Associated With Increased Severity in a Large Cohort of HFE p.Cys282Tyr Homozygous Patients REPLY

McLaren, Gordon D., Barton, James C., Ramm, Grant A., Emond, Mary J., Subramaniam, V. Nathan, Phatak, Pradyumna D., Adams, Paul C., Powell, Lawrie W., Gurrin, Lyle C., Anderson, Gregory J. and McLaren, Christine E. (2017). GNPAT Polymorphism rs11558492 Is Not Associated With Increased Severity in a Large Cohort of HFE p.Cys282Tyr Homozygous Patients REPLY. Hepatology, 65 (3), 1072-1073. doi: 10.1002/hep.29002

GNPAT Polymorphism rs11558492 Is Not Associated With Increased Severity in a Large Cohort of HFE p.Cys282Tyr Homozygous Patients REPLY

2017

Journal Article

The functional roles of T-cadherin in mammalian biology

Sternberg, Jade, Wankell, Miriam, Subramaniam, V. Nathan and Hebbard, Lionel W. (2017). The functional roles of T-cadherin in mammalian biology. AIMS Molecular Science, 4 (1), 62-81. doi: 10.3934/molsci.2017.1.62

The functional roles of T-cadherin in mammalian biology

2017

Journal Article

Ironing out Steatohepatitis

Subramaniam, V. Nathan (2017). Ironing out Steatohepatitis. Annals of Hepatology, 16 (1), 8-9. doi: 10.5604/16652681.1226809

Ironing out Steatohepatitis

2016

Journal Article

Genetic variants in the BMP6 pro-peptide may not cause iron loading and should be interpreted with caution

Mcdonald, Cameron J., Rishi, Gautam, Wallace, Daniel F. and Subramaniam, V. Nathan (2016). Genetic variants in the BMP6 pro-peptide may not cause iron loading and should be interpreted with caution. Gastroenterology, 151 (4), 770-771. doi: 10.1053/j.gastro.2016.03.053

Genetic variants in the BMP6 pro-peptide may not cause iron loading and should be interpreted with caution

2016

Journal Article

Iron and non-alcoholic fatty liver disease

Britton, Laurence J., Subramaniam, V. Nathan and Crawford, Darrell H. G. (2016). Iron and non-alcoholic fatty liver disease. World Journal of Gastroenterology, 22 (36), 8112-8122. doi: 10.3748/wjg.v22.i36.8112

Iron and non-alcoholic fatty liver disease

2016

Journal Article

Hematopoietic deletion of transferrin receptor 2 in mice leads to a block in erythroid differentiation during iron-deficient anemia

Rishi, Gautam, Secondes, Eriza S., Wallace, Daniel F. and Subramaniam, V. Nathan (2016). Hematopoietic deletion of transferrin receptor 2 in mice leads to a block in erythroid differentiation during iron-deficient anemia. American Journal of Hematology, 91 (8), 812-818. doi: 10.1002/ajh.24417

Hematopoietic deletion of transferrin receptor 2 in mice leads to a block in erythroid differentiation during iron-deficient anemia

2016

Journal Article

Pocket-sized iron regulators: One size fits all?

Subramaniam, V. Nathan (2016). Pocket-sized iron regulators: One size fits all?. Blood, 128 (2), 153-154. doi: 10.1182/blood-2016-05-716043

Pocket-sized iron regulators: One size fits all?

2016

Journal Article

Probiotics modify tight-junction proteins in an animal model of nonalcoholic fatty liver disease

Briskey, David, Heritage, Mandy, Jaskowski, Lesley-Anne, Peake, Jonathan, Gobe, Glenda, Subramaniam, V. Nathan, Crawford, Darrell, Campbell, Catherine and Vitetta, Luis (2016). Probiotics modify tight-junction proteins in an animal model of nonalcoholic fatty liver disease. Therapeutic Advances in Gastroenterology, 9 (4), 463-472. doi: 10.1177/1756283X16645055

Probiotics modify tight-junction proteins in an animal model of nonalcoholic fatty liver disease

2016

Journal Article

Heterozygous Hfe gene deletion leads to impaired glucose homeostasis, but not liver injury in mice fed a high-calorie diet

Britton, Laurence, Jaskowski, Lesley, Bridle, Kim, Santrampurwala, Nishreen, Reiling, Janske, Musgrave, Nick, Subramaniam, V. Nathan and Crawford, Darrell (2016). Heterozygous Hfe gene deletion leads to impaired glucose homeostasis, but not liver injury in mice fed a high-calorie diet. Physiological Reports, 4 (12) e12837, e12837. doi: 10.14814/phy2.12837

Heterozygous Hfe gene deletion leads to impaired glucose homeostasis, but not liver injury in mice fed a high-calorie diet

2016

Journal Article

Reply

McLaren, Christine E., Barton, James C., Subramaniam, V. Nathan, Ramm, Grant A., Phatak, Pradyumna D., Emond, Mary J., Gurrin, Lyle C., Adams, Paul C., Powell, Lawrie W., Anderson, Gregory J. and McLaren, Gordon D. (2016). Reply. Hepatology, 63 (6), 2058-2060. doi: 10.1002/hep.28479

Reply

2016

Journal Article

GNPAT variant is not associated with severe iron overload in Irish C282Y homozygotes REPLY

McLaren, Christine E., Barton, James C., Phatak, Pradyumna D., Emond, Mary J., Subramaniam, V. Nathan, Gurrin, Lyle C., Adams, Paul C., Powell, Lawrie W., Ramm, Grant A., Anderson, Gregory J. and McLaren, Gordon D. (2016). GNPAT variant is not associated with severe iron overload in Irish C282Y homozygotes REPLY. Hepatology, 63 (6), 2056-2057. doi: 10.1002/hep.28260

GNPAT variant is not associated with severe iron overload in Irish C282Y homozygotes REPLY