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2013 Journal Article A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicityOancea, Iulia, Png, Chin Wen, Das, Indrajit, Lourie, Rohan, Winkler, Ingrid G., Eri, Rajaraman, Subramaniam, Nathan, Jinnah, H. A., McWhinney, Brett C., Levesque, Jean-Pierre, McGuckin, Michael A., Duley, John A. and Florin, Timothy H. J. (2013). A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicity. Gut, 62 (4), 594-605. doi: 10.1136/gutjnl-2012-302274 |
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2013 Journal Article Centrobin regulates centrosome function in interphase cells by limiting pericentriolar matrix recruitmentJeffery, Jessie M., Grigoriev, Ilya, Poser, Ina, van der Horst, Armando, Hamilton, Nicholas, Waterhouse, Nigel, Bleier, Jonathan, Subramaniam, V. Nathan, Maly, Ivan V., Akhmanova, Anna and Khanna, Kum Kum (2013). Centrobin regulates centrosome function in interphase cells by limiting pericentriolar matrix recruitment. Cell Cycle, 12 (6), 899-906. doi: 10.4161/cc.23879 |
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2013 Journal Article Excess iron modulates endoplasmic reticulum stress-associated pathways in a mouse model of alcohol and high-fat diet-induced liver injuryTan, Terrence C. H., Crawford, Darrell H. G., Jaskowski, Lesley A., Subramaniam,V. Nathan, Clouston, Andrew D., Crane, Denis I., Bridle, Kim R., Anderson, Gregory J. and Fletcher, Linda M. (2013). Excess iron modulates endoplasmic reticulum stress-associated pathways in a mouse model of alcohol and high-fat diet-induced liver injury. Laboratory Investigation, 93 (12), 1295-1312. doi: 10.1038/labinvest.2013.121 |
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2012 Journal Article Hepatic Iron Deposition Does Not Predict Extrahepatic Iron Loading in Mouse Models of Hereditary HemochromatosisSubramaniam, V. Nathan, McDonald, Cameron J., Ostini, Lesa, Lusby, Patricia E., Wockner, Leesa F., Ramm, Grant A. and Wallace, Daniel F. (2012). Hepatic Iron Deposition Does Not Predict Extrahepatic Iron Loading in Mouse Models of Hereditary Hemochromatosis. American Journal of Pathology, 181 (4), 1173-1179. doi: 10.1016/j.ajpath.2012.06.025 |
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2012 Journal Article Iron predicts tolerance in liver transplantationWallace, Daniel F., Crawford, Darrell H. G. and Subramaniam, V. Nathan (2012). Iron predicts tolerance in liver transplantation. Gastroenterology, 143 (3), 862-865. doi: 10.1053/j.gastro.2012.07.091 |
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2011 Journal Article The control of iron homeostasis: MICRORNAS join the partyWallace, Daniel F., Crawford, Darrell H.G. and Subramaniam, V. Nathan (2011). The control of iron homeostasis: MICRORNAS join the party. Gastroenterology, 141 (4), 1520-1522. doi: 10.1053/j.gastro.2011.08.018 |
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2011 Journal Article Iron loading and oxidative stress in the Atm(-/-) mouse liverMcDonald, Cameron J., Ostini, Lesa, Wallace, Daniel F., John, Abraham N., Watters, Dianne J. and Subramaniam, V. Nathan (2011). Iron loading and oxidative stress in the Atm(-/-) mouse liver. American Journal of Physiology: Gastrointestinal and Liver Physiology, 300 (4), G554-G560. doi: 10.1152/ajpgi.00486.2010 |
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2011 Journal Article Blunted hepcidin response to inflammation in the absence of Hfe and transferrin receptor 2Wallace, Daniel F., McDonald, Cameron J., Ostini, Lesa and Subramaniam, V. Nathan (2011). Blunted hepcidin response to inflammation in the absence of Hfe and transferrin receptor 2. Blood, 117 (10), 2960-2966. doi: 10.1182/blood-2010-08-303859 |
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2011 Journal Article G80S-linked ferroportin disease: Classical ferroportin disease in an Asian family and reclassification of the mutant as iron transport defectiveMcDonald, Cameron J., Wallace, Daniel F., Ostini, Lesa, Bell, Sally J., Demediuk, Barbara and Subramaniam, V. Nathan (2011). G80S-linked ferroportin disease: Classical ferroportin disease in an Asian family and reclassification of the mutant as iron transport defective. Journal of Hepatology, 54 (3), 538-544. doi: 10.1016/j.jhep.2010.07.048 |
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2011 Journal Article Altered Lipid Metabolism in Hfe-Knockout Mice Promotes Severe NAFLD and Early FibrosisTan, Terrence C.H., Crawford, Darrell H.G., Jaskowski, Lesley A., Murphy, Therese M., Heritage, Mandy L., Subramaniam, V. Nathan, Clouston, Andrew D., Anderson, Gregory J. and Fletcher, Linda M. (2011). Altered Lipid Metabolism in Hfe-Knockout Mice Promotes Severe NAFLD and Early Fibrosis. American Journal of Physiology: Gastrointestinal and Liver Physiology, 301 (5), 1-39. doi: 10.1152/ajpgi.00150.2011 |
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2010 Journal Article Syntaxin 5 is required for copper homeostasis in Drosophila and mammalsNorgate, Melanie, Southon, Adam, Greenough, Mark, Cater, Michael, Farlow, Ashley, Batterham, Philip, Bush Ashley I., Subramaniam, V. Nathan, Burke, Richard and Camakaris, James (2010). Syntaxin 5 is required for copper homeostasis in Drosophila and mammals. PLoS One, 5 (12) e14303, e14303-1-e14303-10. doi: 10.1371/journal.pone.0014303 |
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2010 Journal Article Transferrin receptor 1: A ferritin receptor as well?Wallace, Daniel F., McDonald, Cameron and Subramaniam, V. Nathan (2010). Transferrin receptor 1: A ferritin receptor as well?. Gastroenterology, 139 (3), 1052-1053. doi: 10.1053/j.gastro.2010.07.030 |
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2010 Journal Article Centrobin regulates the assembly of functional mitotic spindlesJeffery, J. M., Urquhart, A. J., Subramaniam, V. N., Parton, R.G. and Khanna, K.K. (2010). Centrobin regulates the assembly of functional mitotic spindles. Oncogene, 29 (18), 2649-2658. doi: 10.1038/onc.2010.37 |
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2010 Journal Article Increased iron stores correlate with worse disease outcomes in a mouse model of schistosomiasis infectionMcDonald, Cameron J., Jones, Malcolm K., Wallace, Daniel F., Summerville, Lesa, Nawaratna, Sujeevi and Subramaniam, V. Nathan (2010). Increased iron stores correlate with worse disease outcomes in a mouse model of schistosomiasis infection. PLoS One, 5 (3) e9594, 1-7. doi: 10.1371/journal.pone.0009594 |
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2010 Journal Article Functional analysis and theoretical modeling of ferroportin reveals clustering of mutations according to phenotypeWallace, Daniel F., Harris, Jonathan M. and Subramaniam, V. Nathan (2010). Functional analysis and theoretical modeling of ferroportin reveals clustering of mutations according to phenotype. American Journal of Physiology: Cell Physiology, 298 (1), C75-C84. doi: 10.1152/ajpcell.00621.2008 |
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2009 Journal Article Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overloadWallace, Daniel F., Summerville, Lesa, Crampton, Emily M., Frazer, David M., Anderson, Gregory J. and Subramaniam, V. Nathan (2009). Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload. Hepatology, 50 (6), 1992-2000. doi: 10.1002/hep.23198 |
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2009 Journal Article Carrier-Mediated Thyroid Hormone Transport into Placenta by Placental TransthyretinLanders, Kelly A., McKinnon, Brett D., Li, Huika, Subramaniam, V. Nathan, Mortimer, Robin H. and Richard, Kerry (2009). Carrier-Mediated Thyroid Hormone Transport into Placenta by Placental Transthyretin. Journal of Clinical Endocrinology and Metabolism, 94 (7), 2610-2616. doi: 10.1210/jc.2009-0048 |
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2009 Journal Article Co-factors in liver disease: The role of HFE-related hereditary hemochromatosis and ironWallace, Daniel F. and Subramaniam, V. Nathan (2009). Co-factors in liver disease: The role of HFE-related hereditary hemochromatosis and iron. Biochimica et Biophysica Acta - General Subjects, 1790 (7), 663-670. doi: 10.1016/j.bbagen.2008.09.002 |
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2009 Journal Article Hepcidin Regulation by HFE and TFR2: Is It Enough to Give a Hepatocyte a Complex?Wallace, Daniel F., Trinder, Debbie and Subramaniam, V. Nathan (2009). Hepcidin Regulation by HFE and TFR2: Is It Enough to Give a Hepatocyte a Complex?. Gastroenterology, 137 (3), 1173-1175. doi: 10.1053/j.gastro.2009.07.009 |
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2009 Journal Article Serum hyaluronic acid with serum ferritin accurately predicts cirrhosis and reduces the need for liver biopsy in C282Y hemochromatosisCrawford, D. H. G., Murphy, T. L., Ramm, L. E., Fletcher, L. M., Clouston, AD, Anderson, G. J., Subramaniam, V. N., Powell, L. W. and Ramm, G. A. (2009). Serum hyaluronic acid with serum ferritin accurately predicts cirrhosis and reduces the need for liver biopsy in C282Y hemochromatosis. Hepatology, 49 (2), 418-425. doi: 10.1002/hep.22650 |
