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2016

Journal Article

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McLaren, Christine E., Barton, James C., Subramaniam, V. Nathan, Ramm, Grant A., Phatak, Pradyumna D., Emond, Mary J., Gurrin, Lyle C., Adams, Paul C., Powell, Lawrie W., Anderson, Gregory J. and McLaren, Gordon D. (2016). Reply. Hepatology, 63 (6), 2058-2060. doi: 10.1002/hep.28479

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2016

Journal Article

Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics

Kalinowski, Danuta S., Stefani, Christian, Toyokuni, Shinya, Ganz, Tomas, Anderson, Gregory J., Subramaniam, Nathan V., Trinder, Debbie, Olynyk, John K., Chua, Anita, Jansson, Patric J., Sahni, Sumit, Lane, Darius J. R., Merlot, Angelica M., Kovacevic, Zaklina, Huang, Michael L. H., Lee, C. Soon and Richardson, Des R. (2016). Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1863 (4), 727-748. doi: 10.1016/j.bbamcr.2016.01.026

Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics

2016

Journal Article

Normal systemic iron homeostasis in mice with macrophage-specific deletion of transferrin receptor 2

Rishi,Gautam, Secondes, Eriza S., Wallace, Daniel F. and Subramaniam, V. Nathan (2016). Normal systemic iron homeostasis in mice with macrophage-specific deletion of transferrin receptor 2. American Journal of Physiology - Gastrointestinal and Liver Physiology, 310 (3), G171-G180. doi: 10.1152/ajpgi.00291.2015

Normal systemic iron homeostasis in mice with macrophage-specific deletion of transferrin receptor 2

2015

Journal Article

Endofin, a novel BMP-SMAD regulator of the iron-regulatory hormone, hepcidin

Goh, Justin B., Wallace, Daniel F., Hong, Wanjin and Subramaniam, V. Nathan (2015). Endofin, a novel BMP-SMAD regulator of the iron-regulatory hormone, hepcidin. Scientific Reports, 5 (1) 13986, 13986.1-13986.12. doi: 10.1038/srep13986

Endofin, a novel BMP-SMAD regulator of the iron-regulatory hormone, hepcidin

2015

Journal Article

Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload

McLaren, Christine E., Emond, Mary J., Subramaniam, V. Nathan, Phatak, Pradyumna D., Barton, James C., Adams, Paul C., Goh, Justin B., McDonald, Cameron J., Powell, Lawrie W., Gurrin, Lyle C., Allen, Katrina J., Nickerson, Deborah A., Louie, Tin, Ramm, Grant A., Anderson, Gregory J. and McLaren, Gordon D. (2015). Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload. Hepatology, 62 (2), 429-439. doi: 10.1002/hep.27711

Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload

2015

Journal Article

Next-generation sequencing: Application of a novel platform to analyze atypical iron disorders

McDonald, Cameron J., Ostini, Lesa., Wallace, Daniel F., Lyons, Alison., Crawford, Darrell H.G. and Subramaniam, V. Nathan. (2015). Next-generation sequencing: Application of a novel platform to analyze atypical iron disorders. Journal of Hepatology, 63 (5), 1288-1293. doi: 10.1016/j.jhep.2015.06.027

Next-generation sequencing: Application of a novel platform to analyze atypical iron disorders

2015

Journal Article

Analysis of IL-22 contribution to hepcidin induction and hypoferremia during the response to LPS in vivo

Wallace, Daniel F. and Subramaniam, V. Nathan (2015). Analysis of IL-22 contribution to hepcidin induction and hypoferremia during the response to LPS in vivo. International Immunology, 27 (6), 281-287. doi: 10.1093/intimm/dxu144

Analysis of IL-22 contribution to hepcidin induction and hypoferremia during the response to LPS in vivo

2015

Journal Article

Functional analysis of matriptase-2 mutations and domains: Insights into the molecular basis of iron-refractory iron deficiency anemia

McDonald, Cameron J., Ostini, Lesa, Bennett, Nigel, Subramaniam, Nanthakumar, Hooper, John, Velasco, Gloria, Wallace, Daniel F. and Nathan Subramaniam, V. (2015). Functional analysis of matriptase-2 mutations and domains: Insights into the molecular basis of iron-refractory iron deficiency anemia. American Journal of Physiology - Cell Physiology, 308 (7), C539-C547. doi: 10.1152/ajpcell.00264.2014

Functional analysis of matriptase-2 mutations and domains: Insights into the molecular basis of iron-refractory iron deficiency anemia

2015

Journal Article

Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2-/- mice

Bridle, Kim R., Sobbe, Amy L., de Guzman, C. Erika, Santrampurwala, Nishreen, Jaskowski, Lesley A., Clouston, Andrew D., Campbell, Catherine M., Nathan Subramaniam, V. and Crawford, Darrell H. G. (2015). Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2-/- mice. Liver International, 35 (4), 1451-1463. doi: 10.1111/liv.12494

Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2-/- mice

2015

Journal Article

A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction

Wallace, Daniel F., Secondes, Eriza S., Rishi, Gautam, Ostini, Lesa, McDonald, Cameron J., Lane, Steven W., Vu, Therese, Hooper, John D., Velasco, Gloria, Ramsay, Andrew J., Lopez-Otin, Carlos and Subramaniam, V. Nathan (2015). A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction. British Journal of Haematology, 168 (6), 891-901. doi: 10.1111/bjh.13225

A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction

2015

Journal Article

Inconsistent hepatic antifibrotic effects with the iron chelator deferasirox

Sobbe, Amy, Bridle, Kim R., Jaskowski, Lesley, de Guzman, C. Erika, Santrampurwala, Nishreen, Clouston, Andrew D., Campbell, Catherine M., Subramaniam, V. Nathan and Crawford, Darrell H. G. (2015). Inconsistent hepatic antifibrotic effects with the iron chelator deferasirox. Journal of Gastroenterology and Hepatology, 30 (3), 638-645. doi: 10.1111/jgh.12720

Inconsistent hepatic antifibrotic effects with the iron chelator deferasirox

2015

Journal Article

Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload

Mclaren, Christine E., Emond, Mary J., Subramaniam, V. Nathan, Phatak, Pradyumna D., Barton, James C., Adams, Paul C., Powell, Lawrie W., Gurrin, Lyle C., Ramm, Grant A., Anderson, Gregory J. and Mclaren, Gordon D. (2015). Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload. Hepatology, 62 (6), 1918-1919. doi: 10.1002/hep.27851

Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload

2015

Journal Article

Hepcidin: Regulation of the master iron regulator

Rishi, Gautam, Wallace, Daniel F. and Subramaniam, V. Nathan (2015). Hepcidin: Regulation of the master iron regulator. Bioscience Reports, 35 (3) e00192, e00192-e00192. doi: 10.1042/BSR20150014

Hepcidin: Regulation of the master iron regulator

2014

Journal Article

Linking hypoxia and iron homeostasis: a 'plate' full of factors

Subramaniam, V. Nathan and Wallace, Daniel F. (2014). Linking hypoxia and iron homeostasis: a 'plate' full of factors. Gut, 63 (12), 1840-1842. doi: 10.1136/gutjnl-2014-306970

Linking hypoxia and iron homeostasis: a 'plate' full of factors

2014

Journal Article

Parenteral vs. oral iron: influence on hepcidin signaling pathways through analysis of Hfe/Tfr2-null mice

McDonald, Cameron J., Wallace, Daniel F., Ostini, Lesa and Subramaniam, V. Nathan (2014). Parenteral vs. oral iron: influence on hepcidin signaling pathways through analysis of Hfe/Tfr2-null mice. American Journal of Physiology: Gastrointestinal and Liver Physiology, 306 (2), G132-G139. doi: 10.1152/ajpgi.00256.2013

Parenteral vs. oral iron: influence on hepcidin signaling pathways through analysis of Hfe/Tfr2-null mice

2013

Journal Article

Transforming growth factor-β and toll-like receptor-4 polymorphisms are not associated with fibrosis in haemochromatosis

Wood, Marnie J, Powell, Lawrie W, Dixon, Jeannette L, Subramaniam, V. Nathan and Ramm, Grant A (2013). Transforming growth factor-β and toll-like receptor-4 polymorphisms are not associated with fibrosis in haemochromatosis. World Journal of Gastroenterology, 19 (48), 9366-9376. doi: 10.3748/wjg.v19.i48.9366

Transforming growth factor-β and toll-like receptor-4 polymorphisms are not associated with fibrosis in haemochromatosis

2013

Journal Article

A corn oil-based diet protects against combined ethanol and iron-induced liver injury in a mouse model of hemochromatosis

Tan, Terrence C. H., Crawford, Darrell H. G., Jaskowski, Lesley A., Murphy, Therese L., Santrampurwala, Nishreen, Crane, Denis, Clouston, Andrew D., Subramaniam, V. Nathan, Anderson, Gregory J. and Fletcher, Linda M. (2013). A corn oil-based diet protects against combined ethanol and iron-induced liver injury in a mouse model of hemochromatosis. Alcoholism-Clinical and Experimental Research, 37 (10), 1619-1631. doi: 10.1111/acer.12155

A corn oil-based diet protects against combined ethanol and iron-induced liver injury in a mouse model of hemochromatosis

2013

Journal Article

In situ proximity ligation assays indicate that hemochromatosis proteins Hfe and transferrin receptor 2 (Tfr2) do not interact

Rishi, Gautam, Crampton, Emily M., Wallace, Daniel F. and Subramaniam, V. Nathan (2013). In situ proximity ligation assays indicate that hemochromatosis proteins Hfe and transferrin receptor 2 (Tfr2) do not interact. PLoS One, 8 (10) e77267, e77267.1-e77267.11. doi: 10.1371/journal.pone.0077267

In situ proximity ligation assays indicate that hemochromatosis proteins Hfe and transferrin receptor 2 (Tfr2) do not interact

2013

Journal Article

Transthyretin-thyroid hormone internalization by trophoblasts

Landers, K. A., Li, H., Subramaniam, V. N., Mortimer, R. H. and Richard, K. (2013). Transthyretin-thyroid hormone internalization by trophoblasts. Placenta, 34 (8), 716-718. doi: 10.1016/j.placenta.2013.05.005

Transthyretin-thyroid hormone internalization by trophoblasts

2013

Journal Article

Iron storage disease in Asia-Pacific populations: the importance of non-HFE mutations

McDonald, Cameron J., Wallace, Daniel F., Crawford, Darrell H. G. and Subramaniam, V. Nathan (2013). Iron storage disease in Asia-Pacific populations: the importance of non-HFE mutations. Journal of Gastroenterology and Hepatology, 28 (7), 1087-1094. doi: 10.1111/jgh.12222

Iron storage disease in Asia-Pacific populations: the importance of non-HFE mutations