2016 Journal Article ReplyMcLaren, Christine E., Barton, James C., Subramaniam, V. Nathan, Ramm, Grant A., Phatak, Pradyumna D., Emond, Mary J., Gurrin, Lyle C., Adams, Paul C., Powell, Lawrie W., Anderson, Gregory J. and McLaren, Gordon D. (2016). Reply. Hepatology, 63 (6), 2058-2060. doi: 10.1002/hep.28479 |
2016 Journal Article Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeuticsKalinowski, Danuta S., Stefani, Christian, Toyokuni, Shinya, Ganz, Tomas, Anderson, Gregory J., Subramaniam, Nathan V., Trinder, Debbie, Olynyk, John K., Chua, Anita, Jansson, Patric J., Sahni, Sumit, Lane, Darius J. R., Merlot, Angelica M., Kovacevic, Zaklina, Huang, Michael L. H., Lee, C. Soon and Richardson, Des R. (2016). Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1863 (4), 727-748. doi: 10.1016/j.bbamcr.2016.01.026 |
2016 Journal Article Normal systemic iron homeostasis in mice with macrophage-specific deletion of transferrin receptor 2Rishi,Gautam, Secondes, Eriza S., Wallace, Daniel F. and Subramaniam, V. Nathan (2016). Normal systemic iron homeostasis in mice with macrophage-specific deletion of transferrin receptor 2. American Journal of Physiology - Gastrointestinal and Liver Physiology, 310 (3), G171-G180. doi: 10.1152/ajpgi.00291.2015 |
2015 Journal Article Endofin, a novel BMP-SMAD regulator of the iron-regulatory hormone, hepcidinGoh, Justin B., Wallace, Daniel F., Hong, Wanjin and Subramaniam, V. Nathan (2015). Endofin, a novel BMP-SMAD regulator of the iron-regulatory hormone, hepcidin. Scientific Reports, 5 (1) 13986, 13986.1-13986.12. doi: 10.1038/srep13986 |
2015 Journal Article Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overloadMcLaren, Christine E., Emond, Mary J., Subramaniam, V. Nathan, Phatak, Pradyumna D., Barton, James C., Adams, Paul C., Goh, Justin B., McDonald, Cameron J., Powell, Lawrie W., Gurrin, Lyle C., Allen, Katrina J., Nickerson, Deborah A., Louie, Tin, Ramm, Grant A., Anderson, Gregory J. and McLaren, Gordon D. (2015). Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload. Hepatology, 62 (2), 429-439. doi: 10.1002/hep.27711 |
2015 Journal Article Next-generation sequencing: Application of a novel platform to analyze atypical iron disordersMcDonald, Cameron J., Ostini, Lesa., Wallace, Daniel F., Lyons, Alison., Crawford, Darrell H.G. and Subramaniam, V. Nathan. (2015). Next-generation sequencing: Application of a novel platform to analyze atypical iron disorders. Journal of Hepatology, 63 (5), 1288-1293. doi: 10.1016/j.jhep.2015.06.027 |
2015 Journal Article Analysis of IL-22 contribution to hepcidin induction and hypoferremia during the response to LPS in vivoWallace, Daniel F. and Subramaniam, V. Nathan (2015). Analysis of IL-22 contribution to hepcidin induction and hypoferremia during the response to LPS in vivo. International Immunology, 27 (6), 281-287. doi: 10.1093/intimm/dxu144 |
2015 Journal Article Functional analysis of matriptase-2 mutations and domains: Insights into the molecular basis of iron-refractory iron deficiency anemiaMcDonald, Cameron J., Ostini, Lesa, Bennett, Nigel, Subramaniam, Nanthakumar, Hooper, John, Velasco, Gloria, Wallace, Daniel F. and Nathan Subramaniam, V. (2015). Functional analysis of matriptase-2 mutations and domains: Insights into the molecular basis of iron-refractory iron deficiency anemia. American Journal of Physiology - Cell Physiology, 308 (7), C539-C547. doi: 10.1152/ajpcell.00264.2014 |
2015 Journal Article Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2-/- miceBridle, Kim R., Sobbe, Amy L., de Guzman, C. Erika, Santrampurwala, Nishreen, Jaskowski, Lesley A., Clouston, Andrew D., Campbell, Catherine M., Nathan Subramaniam, V. and Crawford, Darrell H. G. (2015). Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2-/- mice. Liver International, 35 (4), 1451-1463. doi: 10.1111/liv.12494 |
2015 Journal Article A critical role for murine transferrin receptor 2 in erythropoiesis during iron restrictionWallace, Daniel F., Secondes, Eriza S., Rishi, Gautam, Ostini, Lesa, McDonald, Cameron J., Lane, Steven W., Vu, Therese, Hooper, John D., Velasco, Gloria, Ramsay, Andrew J., Lopez-Otin, Carlos and Subramaniam, V. Nathan (2015). A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction. British Journal of Haematology, 168 (6), 891-901. doi: 10.1111/bjh.13225 |
2015 Journal Article Inconsistent hepatic antifibrotic effects with the iron chelator deferasiroxSobbe, Amy, Bridle, Kim R., Jaskowski, Lesley, de Guzman, C. Erika, Santrampurwala, Nishreen, Clouston, Andrew D., Campbell, Catherine M., Subramaniam, V. Nathan and Crawford, Darrell H. G. (2015). Inconsistent hepatic antifibrotic effects with the iron chelator deferasirox. Journal of Gastroenterology and Hepatology, 30 (3), 638-645. doi: 10.1111/jgh.12720 |
2015 Journal Article Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overloadMclaren, Christine E., Emond, Mary J., Subramaniam, V. Nathan, Phatak, Pradyumna D., Barton, James C., Adams, Paul C., Powell, Lawrie W., Gurrin, Lyle C., Ramm, Grant A., Anderson, Gregory J. and Mclaren, Gordon D. (2015). Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload. Hepatology, 62 (6), 1918-1919. doi: 10.1002/hep.27851 |
2015 Journal Article Hepcidin: Regulation of the master iron regulatorRishi, Gautam, Wallace, Daniel F. and Subramaniam, V. Nathan (2015). Hepcidin: Regulation of the master iron regulator. Bioscience Reports, 35 (3) e00192, e00192-e00192. doi: 10.1042/BSR20150014 |
2014 Journal Article Linking hypoxia and iron homeostasis: a 'plate' full of factorsSubramaniam, V. Nathan and Wallace, Daniel F. (2014). Linking hypoxia and iron homeostasis: a 'plate' full of factors. Gut, 63 (12), 1840-1842. doi: 10.1136/gutjnl-2014-306970 |
2014 Journal Article Parenteral vs. oral iron: influence on hepcidin signaling pathways through analysis of Hfe/Tfr2-null miceMcDonald, Cameron J., Wallace, Daniel F., Ostini, Lesa and Subramaniam, V. Nathan (2014). Parenteral vs. oral iron: influence on hepcidin signaling pathways through analysis of Hfe/Tfr2-null mice. American Journal of Physiology: Gastrointestinal and Liver Physiology, 306 (2), G132-G139. doi: 10.1152/ajpgi.00256.2013 |
2013 Journal Article Transforming growth factor-β and toll-like receptor-4 polymorphisms are not associated with fibrosis in haemochromatosisWood, Marnie J, Powell, Lawrie W, Dixon, Jeannette L, Subramaniam, V. Nathan and Ramm, Grant A (2013). Transforming growth factor-β and toll-like receptor-4 polymorphisms are not associated with fibrosis in haemochromatosis. World Journal of Gastroenterology, 19 (48), 9366-9376. doi: 10.3748/wjg.v19.i48.9366 |
2013 Journal Article A corn oil-based diet protects against combined ethanol and iron-induced liver injury in a mouse model of hemochromatosisTan, Terrence C. H., Crawford, Darrell H. G., Jaskowski, Lesley A., Murphy, Therese L., Santrampurwala, Nishreen, Crane, Denis, Clouston, Andrew D., Subramaniam, V. Nathan, Anderson, Gregory J. and Fletcher, Linda M. (2013). A corn oil-based diet protects against combined ethanol and iron-induced liver injury in a mouse model of hemochromatosis. Alcoholism-Clinical and Experimental Research, 37 (10), 1619-1631. doi: 10.1111/acer.12155 |
2013 Journal Article In situ proximity ligation assays indicate that hemochromatosis proteins Hfe and transferrin receptor 2 (Tfr2) do not interactRishi, Gautam, Crampton, Emily M., Wallace, Daniel F. and Subramaniam, V. Nathan (2013). In situ proximity ligation assays indicate that hemochromatosis proteins Hfe and transferrin receptor 2 (Tfr2) do not interact. PLoS One, 8 (10) e77267, e77267.1-e77267.11. doi: 10.1371/journal.pone.0077267 |
2013 Journal Article Transthyretin-thyroid hormone internalization by trophoblastsLanders, K. A., Li, H., Subramaniam, V. N., Mortimer, R. H. and Richard, K. (2013). Transthyretin-thyroid hormone internalization by trophoblasts. Placenta, 34 (8), 716-718. doi: 10.1016/j.placenta.2013.05.005 |
2013 Journal Article Iron storage disease in Asia-Pacific populations: the importance of non-HFE mutationsMcDonald, Cameron J., Wallace, Daniel F., Crawford, Darrell H. G. and Subramaniam, V. Nathan (2013). Iron storage disease in Asia-Pacific populations: the importance of non-HFE mutations. Journal of Gastroenterology and Hepatology, 28 (7), 1087-1094. doi: 10.1111/jgh.12222 |