2008 Journal Article Self-adjuvanting lipopeptide vaccinesMoyle, P.M. and Toth, I. (2008). Self-adjuvanting lipopeptide vaccines. Current Medicinal Chemistry, 15 (5), 506-516. doi: 10.2174/092986708783503249 |
2008 Journal Article Increasing entrapment of peptides within poly(alkyl cyanoacrylate) nanoparticles prepared from water-in-oil microemulsions by copolymerizationLiang, M., Davies, N. M. and Toth, I. (2008). Increasing entrapment of peptides within poly(alkyl cyanoacrylate) nanoparticles prepared from water-in-oil microemulsions by copolymerization. International Journal of Pharmaceutics, 362 (1-2), 141-146. doi: 10.1016/j.ijpharm.2008.06.005 |
2007 Journal Article The synthesis and characterisation of a novel dendritic system for gene deliveryColes, Daniel J., Yang, Shu, Esposito, Anna, Mitchell, Deanne, Minchin, Rodney F. and Toth, Istvan (2007). The synthesis and characterisation of a novel dendritic system for gene delivery. Tetrahedron, 63 (49), 12207-12214. doi: 10.1016/j.tet.2007.09.048 |
2007 Journal Article Towards the Development of a Broadly Protective Group A Streptococcal Vaccine Based on the Lipid-Core Peptide SystemOlive, C., Moyle, P. and Toth, I. (2007). Towards the Development of a Broadly Protective Group A Streptococcal Vaccine Based on the Lipid-Core Peptide System. Current Medicinal Chemistry, 14 (28), 2976-2988. doi: 10.2174/092986707782794069 |
2007 Journal Article Enhancement of oral drug absorption - Effect of lipid conjugation on the enzymatic stability and intestinal permeability of L-GlU-L-Trp-NH2Bergeon, JA and Toth, I (2007). Enhancement of oral drug absorption - Effect of lipid conjugation on the enzymatic stability and intestinal permeability of L-GlU-L-Trp-NH2. Bioorganic & Medicinal Chemistry, 15 (22), 7048-7057. doi: 10.1016/j.bmc.2007.07.040 |
2007 Journal Article Design, synthesis and biological evaluation of novel lipoamino acid-based glycolipids for oral drug deliveryFalconer, RA and Toth, I (2007). Design, synthesis and biological evaluation of novel lipoamino acid-based glycolipids for oral drug delivery. Bioorganic & Medicinal Chemistry, 15 (22), 7012-7020. doi: 10.1016/j.bmc.2007.07.048 |
2007 Journal Article Oral absorption and in vivo biodistribution of alpha-conotoxin MII and a lipidic analogueBlanchfield, J., Gallagher, O., Cros, C., Lewis, R., Alewood, P. and Toth, I. (2007). Oral absorption and in vivo biodistribution of alpha-conotoxin MII and a lipidic analogue. Biochemical and Biophysical Research Communication, 361 (1), 97-102. doi: 10.1016/j.bbrc.2007.06.138 |
2007 Journal Article A technique for the synthesis of highly-pure, mono-epitopic, multi-valent lipid core peptide vaccinesMoyle, PM, Hari, Y, Huang, N, Olive, C, Good, MF and Toth, I (2007). A technique for the synthesis of highly-pure, mono-epitopic, multi-valent lipid core peptide vaccines. Tetrahedron Letters, 48 (29), 4965-4967. doi: 10.1016/j.tetlet.2007.05.129 |
2007 Journal Article Caco-2 cell permeability and stability of two D-glucopyranuronamide conjugates of thyrotropin-releasing hormoneWessling, Susanne T., Ross, Benjamin P., Koda, Yasuko, Blanchfield, Joanne T. and Toth, Istvan (2007). Caco-2 cell permeability and stability of two D-glucopyranuronamide conjugates of thyrotropin-releasing hormone. Bioorganic & Medicinal Chemistry, 15 (14), 4946-4950. doi: 10.1016/j.bmc.2007.04.042 |
2007 Journal Article Evaluation of Cell Tolerability of a Series of Lipoamino Acids Using Biological Membranes and a Biomembrane Model.Pignatello, R., Noce, C., Campisi, A., Acquaviva, R., Bucolo, C., Puglisi, G. and Toth, I. (2007). Evaluation of Cell Tolerability of a Series of Lipoamino Acids Using Biological Membranes and a Biomembrane Model.. Current Drug Delivery, 4 (2), 109-121. doi: 10.2174/156720107780362348 |
2007 Journal Article Novel cationic lipophilic peptides for oligodeoxynucleotide deliveryChan, E, Amon, M, Marano, R. J., Wimmer, N, Kearns, P. S., Manolios, N, Rakoczy, P. E. and Toth, I (2007). Novel cationic lipophilic peptides for oligodeoxynucleotide delivery. Bioorganic & Medicinal Chemistry, 15 (12), 4091-4097. doi: 10.1016/j.bmc.2007.03.078 |
2007 Journal Article Toward the development of prophylactic and therapeutic human papillomavirus type-16 lipopeptide vaccinesMoyle, Peter M., Olive, Colleen, Ho, Mei-Fong, Pandey, Manisha, Dyer, Joanne, Suhrbier, Andreas, Fujita, Yoshio and Toth, Istvan (2007). Toward the development of prophylactic and therapeutic human papillomavirus type-16 lipopeptide vaccines. Journal of Medicinal Chemistry, 50 (19), 4721-4727. doi: 10.1021/jm070287b |
2007 Journal Article The anti-mutagenic and antioxidant effects of bile pigments in the Ames Salmonella testBulmer, A., Ried, K., Coombes, J., Blanchfield, J., Toth, I. and Wagner, K. (2007). The anti-mutagenic and antioxidant effects of bile pigments in the Ames Salmonella test. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 629 (2), 122-132. doi: 10.1016/j.mrgentox.2007.01.008 |
2007 Journal Article Comparison of the in vitro apparent permeability and stability of opioid mimetic compounds with that of the native peptideKoda, Y., Shiotani, K., Toth, I., Tsuda, Y., Okada, Y. and Blanchfield, J. (2007). Comparison of the in vitro apparent permeability and stability of opioid mimetic compounds with that of the native peptide. Bioorganic & Medicinal Chemistry Letters, 17 (7), 2043-2046. doi: 10.1016/j.bmcl.2007.01.051 |
2007 Journal Article Permeability studies of Kavalactones using a Caco-2 cell monolayer modelMatthias, A., Blanchfield, J., Penman, K., Bone, K., Toth, I. and Lehmann, R. (2007). Permeability studies of Kavalactones using a Caco-2 cell monolayer model. Journal of Clinical Pharmacy and Therapeutics, 32 (3), 233-239. doi: 10.1111/j.1365-2710.2007.00810.x |
2007 Journal Article Enhanced protection against Streptococcus pyogenes infection by intranasal vaccination with a dual antigen component M protein/SfbI lipid core peptide vaccine formulationOlive, C., Schulze, K., Sun, H. K., Ebensen, T., Horváth, A., Toth, I. and Guzman, C. A. (2007). Enhanced protection against Streptococcus pyogenes infection by intranasal vaccination with a dual antigen component M protein/SfbI lipid core peptide vaccine formulation. Vaccine, 25 (10), 1789-1797. doi: 10.1016/j.vaccine.2006.11.031 |
2007 Journal Article Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolaseKim, I., Nishi, I., Tsai, H., Bradford, T., Koda, Y., Watanabe, T., Morriseau, C., Blanchfield, J., Toth, I. and Hammock, B. (2007). Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase. Bioorganic & Medicinal Chemistry, 15 (1), 312-323. doi: 10.1016/j.bmc.2006.09.057 |
2007 Journal Article Modified Influenza Virosomes: Recent Advances and Potential in Gene DeliveryKhoshnejad, M., Young, P. R., Toth, I. and Minchin, R. F. (2007). Modified Influenza Virosomes: Recent Advances and Potential in Gene Delivery. Current Medicinal Chemistry, 14 (29), 3152-3156. doi: 10.2174/092986707782793989 |
2007 Journal Article A védőoltások gyógyszerkémiájának egyik legújabb fejezete. Zsír-aminosav komplexen alapuló vakcinák (Recent developments in prophylactic drug chemistry. Vaccines based on fatty-amino acid complexes)Toth, I. (2007). A védőoltások gyógyszerkémiájának egyik legújabb fejezete. Zsír-aminosav komplexen alapuló vakcinák (Recent developments in prophylactic drug chemistry. Vaccines based on fatty-amino acid complexes). Magyar kémikusok lapja, 62, 274-276. |
2006 Journal Article Method for the Synthesis of Multi-Epitopic Streptococcus pyogenes Lipopeptide Vaccines Using Native Chemical LigationMoyle, P. M., Olive, C., Ho, M. F., Burgess, M., Karpati, L., Good, M. F. and Toth, I. (2006). Method for the Synthesis of Multi-Epitopic Streptococcus pyogenes Lipopeptide Vaccines Using Native Chemical Ligation. Journal of Organic Chemistry, 71 (18), 6846-6850. doi: 10.1021/jo060960p |