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2008

Journal Article

Self-adjuvanting lipopeptide vaccines

Moyle, P.M. and Toth, I. (2008). Self-adjuvanting lipopeptide vaccines. Current Medicinal Chemistry, 15 (5), 506-516. doi: 10.2174/092986708783503249

Self-adjuvanting lipopeptide vaccines

2008

Journal Article

Increasing entrapment of peptides within poly(alkyl cyanoacrylate) nanoparticles prepared from water-in-oil microemulsions by copolymerization

Liang, M., Davies, N. M. and Toth, I. (2008). Increasing entrapment of peptides within poly(alkyl cyanoacrylate) nanoparticles prepared from water-in-oil microemulsions by copolymerization. International Journal of Pharmaceutics, 362 (1-2), 141-146. doi: 10.1016/j.ijpharm.2008.06.005

Increasing entrapment of peptides within poly(alkyl cyanoacrylate) nanoparticles prepared from water-in-oil microemulsions by copolymerization

2007

Journal Article

The synthesis and characterisation of a novel dendritic system for gene delivery

Coles, Daniel J., Yang, Shu, Esposito, Anna, Mitchell, Deanne, Minchin, Rodney F. and Toth, Istvan (2007). The synthesis and characterisation of a novel dendritic system for gene delivery. Tetrahedron, 63 (49), 12207-12214. doi: 10.1016/j.tet.2007.09.048

The synthesis and characterisation of a novel dendritic system for gene delivery

2007

Journal Article

Towards the Development of a Broadly Protective Group A Streptococcal Vaccine Based on the Lipid-Core Peptide System

Olive, C., Moyle, P. and Toth, I. (2007). Towards the Development of a Broadly Protective Group A Streptococcal Vaccine Based on the Lipid-Core Peptide System. Current Medicinal Chemistry, 14 (28), 2976-2988. doi: 10.2174/092986707782794069

Towards the Development of a Broadly Protective Group A Streptococcal Vaccine Based on the Lipid-Core Peptide System

2007

Journal Article

Enhancement of oral drug absorption - Effect of lipid conjugation on the enzymatic stability and intestinal permeability of L-GlU-L-Trp-NH2

Bergeon, JA and Toth, I (2007). Enhancement of oral drug absorption - Effect of lipid conjugation on the enzymatic stability and intestinal permeability of L-GlU-L-Trp-NH2. Bioorganic & Medicinal Chemistry, 15 (22), 7048-7057. doi: 10.1016/j.bmc.2007.07.040

Enhancement of oral drug absorption - Effect of lipid conjugation on the enzymatic stability and intestinal permeability of L-GlU-L-Trp-NH2

2007

Journal Article

Design, synthesis and biological evaluation of novel lipoamino acid-based glycolipids for oral drug delivery

Falconer, RA and Toth, I (2007). Design, synthesis and biological evaluation of novel lipoamino acid-based glycolipids for oral drug delivery. Bioorganic & Medicinal Chemistry, 15 (22), 7012-7020. doi: 10.1016/j.bmc.2007.07.048

Design, synthesis and biological evaluation of novel lipoamino acid-based glycolipids for oral drug delivery

2007

Journal Article

Oral absorption and in vivo biodistribution of alpha-conotoxin MII and a lipidic analogue

Blanchfield, J., Gallagher, O., Cros, C., Lewis, R., Alewood, P. and Toth, I. (2007). Oral absorption and in vivo biodistribution of alpha-conotoxin MII and a lipidic analogue. Biochemical and Biophysical Research Communication, 361 (1), 97-102. doi: 10.1016/j.bbrc.2007.06.138

Oral absorption and in vivo biodistribution of alpha-conotoxin MII and a lipidic analogue

2007

Journal Article

A technique for the synthesis of highly-pure, mono-epitopic, multi-valent lipid core peptide vaccines

Moyle, PM, Hari, Y, Huang, N, Olive, C, Good, MF and Toth, I (2007). A technique for the synthesis of highly-pure, mono-epitopic, multi-valent lipid core peptide vaccines. Tetrahedron Letters, 48 (29), 4965-4967. doi: 10.1016/j.tetlet.2007.05.129

A technique for the synthesis of highly-pure, mono-epitopic, multi-valent lipid core peptide vaccines

2007

Journal Article

Caco-2 cell permeability and stability of two D-glucopyranuronamide conjugates of thyrotropin-releasing hormone

Wessling, Susanne T., Ross, Benjamin P., Koda, Yasuko, Blanchfield, Joanne T. and Toth, Istvan (2007). Caco-2 cell permeability and stability of two D-glucopyranuronamide conjugates of thyrotropin-releasing hormone. Bioorganic & Medicinal Chemistry, 15 (14), 4946-4950. doi: 10.1016/j.bmc.2007.04.042

Caco-2 cell permeability and stability of two D-glucopyranuronamide conjugates of thyrotropin-releasing hormone

2007

Journal Article

Evaluation of Cell Tolerability of a Series of Lipoamino Acids Using Biological Membranes and a Biomembrane Model.

Pignatello, R., Noce, C., Campisi, A., Acquaviva, R., Bucolo, C., Puglisi, G. and Toth, I. (2007). Evaluation of Cell Tolerability of a Series of Lipoamino Acids Using Biological Membranes and a Biomembrane Model.. Current Drug Delivery, 4 (2), 109-121. doi: 10.2174/156720107780362348

Evaluation of Cell Tolerability of a Series of Lipoamino Acids Using Biological Membranes and a Biomembrane Model.

2007

Journal Article

Novel cationic lipophilic peptides for oligodeoxynucleotide delivery

Chan, E, Amon, M, Marano, R. J., Wimmer, N, Kearns, P. S., Manolios, N, Rakoczy, P. E. and Toth, I (2007). Novel cationic lipophilic peptides for oligodeoxynucleotide delivery. Bioorganic & Medicinal Chemistry, 15 (12), 4091-4097. doi: 10.1016/j.bmc.2007.03.078

Novel cationic lipophilic peptides for oligodeoxynucleotide delivery

2007

Journal Article

Toward the development of prophylactic and therapeutic human papillomavirus type-16 lipopeptide vaccines

Moyle, Peter M., Olive, Colleen, Ho, Mei-Fong, Pandey, Manisha, Dyer, Joanne, Suhrbier, Andreas, Fujita, Yoshio and Toth, Istvan (2007). Toward the development of prophylactic and therapeutic human papillomavirus type-16 lipopeptide vaccines. Journal of Medicinal Chemistry, 50 (19), 4721-4727. doi: 10.1021/jm070287b

Toward the development of prophylactic and therapeutic human papillomavirus type-16 lipopeptide vaccines

2007

Journal Article

The anti-mutagenic and antioxidant effects of bile pigments in the Ames Salmonella test

Bulmer, A., Ried, K., Coombes, J., Blanchfield, J., Toth, I. and Wagner, K. (2007). The anti-mutagenic and antioxidant effects of bile pigments in the Ames Salmonella test. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 629 (2), 122-132. doi: 10.1016/j.mrgentox.2007.01.008

The anti-mutagenic and antioxidant effects of bile pigments in the Ames Salmonella test

2007

Journal Article

Comparison of the in vitro apparent permeability and stability of opioid mimetic compounds with that of the native peptide

Koda, Y., Shiotani, K., Toth, I., Tsuda, Y., Okada, Y. and Blanchfield, J. (2007). Comparison of the in vitro apparent permeability and stability of opioid mimetic compounds with that of the native peptide. Bioorganic & Medicinal Chemistry Letters, 17 (7), 2043-2046. doi: 10.1016/j.bmcl.2007.01.051

Comparison of the in vitro apparent permeability and stability of opioid mimetic compounds with that of the native peptide

2007

Journal Article

Permeability studies of Kavalactones using a Caco-2 cell monolayer model

Matthias, A., Blanchfield, J., Penman, K., Bone, K., Toth, I. and Lehmann, R. (2007). Permeability studies of Kavalactones using a Caco-2 cell monolayer model. Journal of Clinical Pharmacy and Therapeutics, 32 (3), 233-239. doi: 10.1111/j.1365-2710.2007.00810.x

Permeability studies of Kavalactones using a Caco-2 cell monolayer model

2007

Journal Article

Enhanced protection against Streptococcus pyogenes infection by intranasal vaccination with a dual antigen component M protein/SfbI lipid core peptide vaccine formulation

Olive, C., Schulze, K., Sun, H. K., Ebensen, T., Horváth, A., Toth, I. and Guzman, C. A. (2007). Enhanced protection against Streptococcus pyogenes infection by intranasal vaccination with a dual antigen component M protein/SfbI lipid core peptide vaccine formulation. Vaccine, 25 (10), 1789-1797. doi: 10.1016/j.vaccine.2006.11.031

Enhanced protection against Streptococcus pyogenes infection by intranasal vaccination with a dual antigen component M protein/SfbI lipid core peptide vaccine formulation

2007

Journal Article

Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase

Kim, I., Nishi, I., Tsai, H., Bradford, T., Koda, Y., Watanabe, T., Morriseau, C., Blanchfield, J., Toth, I. and Hammock, B. (2007). Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase. Bioorganic & Medicinal Chemistry, 15 (1), 312-323. doi: 10.1016/j.bmc.2006.09.057

Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase

2007

Journal Article

Modified Influenza Virosomes: Recent Advances and Potential in Gene Delivery

Khoshnejad, M., Young, P. R., Toth, I. and Minchin, R. F. (2007). Modified Influenza Virosomes: Recent Advances and Potential in Gene Delivery. Current Medicinal Chemistry, 14 (29), 3152-3156. doi: 10.2174/092986707782793989

Modified Influenza Virosomes: Recent Advances and Potential in Gene Delivery

2007

Journal Article

A védőoltások gyógyszerkémiájának egyik legújabb fejezete. Zsír-aminosav komplexen alapuló vakcinák (Recent developments in prophylactic drug chemistry. Vaccines based on fatty-amino acid complexes)

Toth, I. (2007). A védőoltások gyógyszerkémiájának egyik legújabb fejezete. Zsír-aminosav komplexen alapuló vakcinák (Recent developments in prophylactic drug chemistry. Vaccines based on fatty-amino acid complexes). Magyar kémikusok lapja, 62, 274-276.

A védőoltások gyógyszerkémiájának egyik legújabb fejezete. Zsír-aminosav komplexen alapuló vakcinák (Recent developments in prophylactic drug chemistry. Vaccines based on fatty-amino acid complexes)

2006

Journal Article

Method for the Synthesis of Multi-Epitopic Streptococcus pyogenes Lipopeptide Vaccines Using Native Chemical Ligation

Moyle, P. M., Olive, C., Ho, M. F., Burgess, M., Karpati, L., Good, M. F. and Toth, I. (2006). Method for the Synthesis of Multi-Epitopic Streptococcus pyogenes Lipopeptide Vaccines Using Native Chemical Ligation. Journal of Organic Chemistry, 71 (18), 6846-6850. doi: 10.1021/jo060960p

Method for the Synthesis of Multi-Epitopic Streptococcus pyogenes Lipopeptide Vaccines Using Native Chemical Ligation