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2006 Journal Article Intranasal administration is an effective mucosal vaccine delivery route for self-adjuvanting lipid core peptides targeting the group A streptococcal M proteinOlive, Colleen, Sun, Hsien Kuo, Ho, Mei‐Fong, Dyer, Joanne, Horvath, Aniko, Toth, Istvan and Good, Michael F. (2006). Intranasal administration is an effective mucosal vaccine delivery route for self-adjuvanting lipid core peptides targeting the group A streptococcal M protein. Journal of Infectious Diseases, 194 (3), 316-324. doi: 10.1086/505580 |
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2006 Journal Article Lipidation and glycosylation of a T cell antigen receptor (TCR) transmembrane hvdrophobic peptide dramatically enhances in vitro and in vivo functionAmon, Michael A., Ali, Marina, Bender, Vera, Chan, Yiu-Ngok, Toth, Istvan and Manolios, Nicholas (2006). Lipidation and glycosylation of a T cell antigen receptor (TCR) transmembrane hvdrophobic peptide dramatically enhances in vitro and in vivo function. Biochimica Et Biophysica Acta-molecular Cell Research, 1763 (8), 879-888. doi: 10.1016/j.bbamcr.2006.04.013 |
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2006 Journal Article Immunization with a tetraepitopic lipid core peptide vaccine construct induces broadly protective immune responses against group A streptococcusOlive, Colleen, Ho, Mei‐Fong, Dyer, Joanne, Lincoln, Douglas, Barozzi, Nadia, Toth, Istvan and Good, Michael F. (2006). Immunization with a tetraepitopic lipid core peptide vaccine construct induces broadly protective immune responses against group A streptococcus. Journal of Infectious Diseases, 193 (12), 1666-1676. doi: 10.1086/504266 |
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2006 Journal Article The lipid core peptide system in vaccine deliveryToth, Istvan, Moyle, Peter, Karpati, Levente, Horvath, Aniko, Olive, Colleen and Good, Michael (2006). The lipid core peptide system in vaccine delivery. International Congress Series, 1289, 307-310. doi: 10.1016/j.ics.2005.11.057 |
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2006 Journal Article Synthesis of a highly pure lipid core peptide based self-adjuvanting triepitopic group A Streptococcal vaccine, and subsequent immunological evaluationMoyle, P. M., Olive, C., Ho, M. F., Good, M. F. and Toth, I. (2006). Synthesis of a highly pure lipid core peptide based self-adjuvanting triepitopic group A Streptococcal vaccine, and subsequent immunological evaluation. Journal of Medicinal Chemistry, 49 (21), 6364-6370. doi: 10.1021/jm060475m |
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2006 Journal Article Method for the synthesis of highly pure vaccines using the lipid core peptide systemMoyle, P. M., Olive, C., Good, M. F. and Toth, I. (2006). Method for the synthesis of highly pure vaccines using the lipid core peptide system. Journal of Peptide Science, 12 (12), 800-807. doi: 10.1002/psc.815 |
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2006 Journal Article Dde as a protecting group for carbohydrate synthesisBornaghi, L., Dekany, G., Drinnan, N. B., Taylor, S., Toth, I. and West, M. L. (2006). Dde as a protecting group for carbohydrate synthesis. Journal of Carbohydrate Chemistry, 25 (1), 1-18. doi: 10.1080/07328300500388685 |
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2006 Journal Article Epidermal penetration of a therapeutic peptide by lipid conjugation; Stereo-selective peptide availability of a topical diastereomeric lipopeptideCaccetta, R., Blanchfield, J. T., Harrison, J., Toth, I. and Benson, H. A. E. (2006). Epidermal penetration of a therapeutic peptide by lipid conjugation; Stereo-selective peptide availability of a topical diastereomeric lipopeptide. International Journal of Peptide Research and Therapeutics, 12 (3), 327-333. doi: 10.1007/s10989-006-9024-5 |
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2006 Journal Article Particulate systems as adjuvants and carriers for peptide and protein antigensLiang, M T, Davies, N M, Blanchfield, J T and Toth, I (2006). Particulate systems as adjuvants and carriers for peptide and protein antigens. Current Drug Delivery, 3 (4), 379-388. doi: 10.2174/156720106778559029 |
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2006 Journal Article Protein transduction by lipidic peptide dendrimersBayele, Henry K., Ramaswamy, Chandrasekaran, Wilderspin, Andrew F., Srai, Kaila S., Toth, Istvan and Florence, Alexander T. (2006). Protein transduction by lipidic peptide dendrimers. Journal of Pharmaceutical Sciences, 95 (6), 1227-1237. doi: 10.1002/jps.20606 |
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2006 Journal Article Towards the synthesis of a highly pure, multiepitopic, mucosal group A streptoccal lipopeptide vaccineMoyle, P. M., Olive, C., Ho, M.-F., Burgess, M., Karpati, L., Good, M. F. and Toth, I. (2006). Towards the synthesis of a highly pure, multiepitopic, mucosal group A streptoccal lipopeptide vaccine. International Congress Series, 1289, 324-328. doi: 10.1016/j.ics.2005.11.084 |
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2006 Journal Article Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibitionParekh, H. S., Marano, R. J., Rakoczy, E. P., Blanchfield, J. and Toth, I. (2006). Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibition. Bioorganic & Medicinal Chemistry, 14 (14), 4775-4780. doi: 10.1016/j.bmc.2006.03.029 |
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2006 Journal Article Immunogenicity of liposomes containing lipid core peptides and the adjuvant Quil AWhite, Karen, Rades, Thomas, Kearns, Philip, Toth, Istvan and Hook, Sarah (2006). Immunogenicity of liposomes containing lipid core peptides and the adjuvant Quil A. Pharmaceutical Research, 23 (7), 1473-1481. doi: 10.1007/s11095-006-0272-z |
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2006 Journal Article Polycationic lipophilic-core dendrons as penetration enhancers for the oral administration of low molecular weight heparinHayes, Patricia Y., Ross, Benjamin P., Thomas, Bradley G. and Toth, Istvan (2006). Polycationic lipophilic-core dendrons as penetration enhancers for the oral administration of low molecular weight heparin. Bioorganic & Medicinal Chemistry, 14 (1), 143-152. doi: 10.1016/j.bmc.2005.08.004 |
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2006 Journal Article Specific modulation of airway epithelial tight junctions by apical application of an occludin peptideEverett, Ruth S., Vanhook, Miriam K., Barozzi, Nadia, Toth, Istvan and Johnson, Larry G. (2006). Specific modulation of airway epithelial tight junctions by apical application of an occludin peptide. Molecular Pharmacology, 69 (2), 492-500. doi: 10.1124/mol.105.017251 |
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2006 Journal Article Enhancement of drug affinity for cell membranes by conjugation with lipoamino acids II. Experimental and computational evidence using biomembrane modelsPignatello, Rosario, Guccione, Salvatore, Castelli, Francesco, Sarpietro, Maria G., Giurato, Laura, Lombardo, Massimo, Puglisi, Giovanni and Toth, Istvan (2006). Enhancement of drug affinity for cell membranes by conjugation with lipoamino acids II. Experimental and computational evidence using biomembrane models. International Journal of Pharmaceutics, 310 (1-2), 53-63. doi: 10.1016/j.ijpharm.2005.11.044 |
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2006 Journal Article Anti-proliferative effects of novel Glyco-lipid-arsenicals (III) on MCF-7 human breast cancer cellsWimmer, N., Robinson, J. A., Gopisetty Venkata, N., Roberts-Thomson, S. J., Monteith, G. R. and Toth, I. (2006). Anti-proliferative effects of novel Glyco-lipid-arsenicals (III) on MCF-7 human breast cancer cells. Medicinal Chemistry, 2 (1), 79-87. doi: 10.2174/157340606775197714 |
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2006 Journal Article Investigation of the route of absorption of lipid and sugar modified leu-enkephalin analogues and their enzymatic stability using the Caco-2 cell monolayer systemWu, S., Christopher, C., Koda, Y., Blanchfield, J. T. and Toth, I. (2006). Investigation of the route of absorption of lipid and sugar modified leu-enkephalin analogues and their enzymatic stability using the Caco-2 cell monolayer system. Medicinal Chemistry, 2 (2), 203-211. doi: 10.2174/157340606776056205 |
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2005 Journal Article Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: A long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicityMarano, R. J., Toth, I., Wimmer, N., Brankov, M. and Rakoczy, E. P. (2005). Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: A long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity. Gene Therapy, 12 (21), 1544-1550. doi: 10.1038/sj.gt.3302579 |
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2005 Journal Article Gastrointestinal absorption of Heparin by lipidization or coadministration with penetration enhancersRoss, B. P. and Toth, I. (2005). Gastrointestinal absorption of Heparin by lipidization or coadministration with penetration enhancers. Current Drug Delivery, 2 (3), 277-287. doi: 10.2174/1567201054367968 |
