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2005

Journal Article

Functional implications of modifying RyR‐activating peptides for membrane permeability

Dulhunty, Angela F., Cengia, Louise, Young, Jacqui, Pace, Suzy M., Harvey, Peta J., Lamb, Graham D., Chan, Yiu-Ngok, Wimmer, Norbert, Toth, Istvan and Casarotto, Marco G. (2005). Functional implications of modifying RyR‐activating peptides for membrane permeability. British Journal of Pharmacology, 144 (6), 743-754. doi: 10.1038/sj.bjp.0705981

Functional implications of modifying RyR‐activating peptides for membrane permeability

2005

Journal Article

Chemo-enzymatic synthesis of a trisaccharide-linked peptide aimed at improved drug-delivery

Johnstone, K. D., Dieckelmann, M., Jennings, M. P., Toth, I. and Blanchfield, J. T. (2005). Chemo-enzymatic synthesis of a trisaccharide-linked peptide aimed at improved drug-delivery. Current Drug Delivery, 2 (3), 215-222. doi: 10.2174/1567201054367977

Chemo-enzymatic synthesis of a trisaccharide-linked peptide aimed at improved drug-delivery

2005

Journal Article

Encapsulation of lipopeptides within liposomes: Effect of number of lipid chains, chain length and method of liposome preparation

Liang, M. T., Davies, N. M. and Toth, I. (2005). Encapsulation of lipopeptides within liposomes: Effect of number of lipid chains, chain length and method of liposome preparation. International Journal of Pharmaceutics, 301 (1-2), 247-254. doi: 10.1016/j.ijpharm.2005.06.010

Encapsulation of lipopeptides within liposomes: Effect of number of lipid chains, chain length and method of liposome preparation

2005

Journal Article

Versatile peptide dendrimers for nucleic acid delivery

Bayele, Henry, Sakthivel, T., O'Donell, Martin, Pasi, K. John, Wilderspin, Andrew F., Lee, Christine A., Toth, Istvan and Florence, Alexander T. (2005). Versatile peptide dendrimers for nucleic acid delivery. Journal of Pharmaceutical Sciences, 94 (2), 446-457. doi: 10.1002/jps.20230

Versatile peptide dendrimers for nucleic acid delivery

2005

Journal Article

The stability of lipidic analogues of GnRH in plasma and kidney preparations: the stereoselective release of the parent peptide

Blanchfield, J. T., Lew, R. A., Smith, A. I. and Toth, I. (2005). The stability of lipidic analogues of GnRH in plasma and kidney preparations: the stereoselective release of the parent peptide. Bioorganic & Medicinal Chemistry Letters, 15 (6), 1609-1612. doi: 10.1016/j.bmcl.2005.01.069

The stability of lipidic analogues of GnRH in plasma and kidney preparations: the stereoselective release of the parent peptide

2004

Journal Article

Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide

Marano, Robert J., Wimmer, Norbert, Kearns, Philip S., Thomas, Bradley G., Toth, Istvan, Brankov, Meliha and Rakoczy, P. Elizabeth (2004). Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide. Experimental Eye Research, 79 (4), 525-535. doi: 10.1016/j.exer.2004.06.023

Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide

2004

Journal Article

Increased adjuvant activity of minimal CD8 T cell peptides incorporated into lipid-core-peptides

White, K., Kearns, P., Toth, I. and Hook, S. (2004). Increased adjuvant activity of minimal CD8 T cell peptides incorporated into lipid-core-peptides. Immunology And Cell Biology, 82 (5), 517-522. doi: 10.1111/j.1440-1711.2004.01269.x

Increased adjuvant activity of minimal CD8 T cell peptides incorporated into lipid-core-peptides

2004

Journal Article

Micellar aggregation and membrane partitioning of bile salts, fatty acids, sodium dodecyl sulfate, and sugar-conjugated fatty acids: correlation with hemolytic potency and implications for drug delivery

Ross, Benjamin P., Braddy, April C., McGeary, Ross P., Blanchfield, Joanne T., Prokai, Laszlo and Toth, Istvan (2004). Micellar aggregation and membrane partitioning of bile salts, fatty acids, sodium dodecyl sulfate, and sugar-conjugated fatty acids: correlation with hemolytic potency and implications for drug delivery. Molecular Pharmaceutics, 1 (3), 233-245. doi: 10.1021/mp049964d

Micellar aggregation and membrane partitioning of bile salts, fatty acids, sodium dodecyl sulfate, and sugar-conjugated fatty acids: correlation with hemolytic potency and implications for drug delivery

2004

Journal Article

Permeability studies of alkylamides and caffeic acid conjugates from echinacea using a Caco-2 cell monolayer model

Matthias, A., Blanchfield, J. T., Penman, K. G., Toth, I., Lang, C. S., De Voss, J. J. and Lehmann, R. P. (2004). Permeability studies of alkylamides and caffeic acid conjugates from echinacea using a Caco-2 cell monolayer model. Journal of Clinical Pharmacy And Therapeutics, 29 (1), 7-13. doi: 10.1046/j.1365-2710.2003.00530.x

Permeability studies of alkylamides and caffeic acid conjugates from echinacea using a Caco-2 cell monolayer model

2004

Journal Article

Nucleophilic substitution reactions of pyranose polytosylates

McGeary, R. P., Rasoul Amini, S., Tang, V. W. S. and Toth, I. (2004). Nucleophilic substitution reactions of pyranose polytosylates. Journal of Organic Chemistry, 69 (8), 2727-2730. doi: 10.1021/jo035779k

Nucleophilic substitution reactions of pyranose polytosylates

2004

Journal Article

Design, Synthesis, and Evaluation of a Liposaccharide Drug Delivery Agent: Application to the Gastrointestinal Absorption of Gentamicin

Ross, B. P., DeCruz, S. E., Lynch, T. B., Davis-Goff, K. and Toth, I. (2004). Design, Synthesis, and Evaluation of a Liposaccharide Drug Delivery Agent: Application to the Gastrointestinal Absorption of Gentamicin. Journal of Medicinal Chemistry, 47 (5), 1251-1258. doi: 10.1021/jm030474j

Design, Synthesis, and Evaluation of a Liposaccharide Drug Delivery Agent: Application to the Gastrointestinal Absorption of Gentamicin

2004

Journal Article

Lipid core peptide technology and group A streptococcal vaccine delivery

Olive, C., Batzloff, M.R. and Toth, I. (2004). Lipid core peptide technology and group A streptococcal vaccine delivery. Expert Review of Vaccines, 3 (1), 43-58. doi: 10.1586/14760584.3.1.43

Lipid core peptide technology and group A streptococcal vaccine delivery

2004

Journal Article

Urotensin-II-converting enzyme activity of furin and trypsin in human cells in vitro

Russell, F. D., Kearns, P., Toth, I. and Molenaar, P. (2004). Urotensin-II-converting enzyme activity of furin and trypsin in human cells in vitro. Journal of Pharmacology And Experimental Therapeutics, 310 (1), 209-214. doi: 10.1124/jpet.104.065425

Urotensin-II-converting enzyme activity of furin and trypsin in human cells in vitro

2004

Journal Article

Mucosal immunization: Adjuvants and delivery systems

Moyle, P.M., McGeary, R. P., Blanchfield, J. T. and Toth, I. (2004). Mucosal immunization: Adjuvants and delivery systems. Current Drug Delivery, 1 (4), 385-396. doi: 10.2174/1567201043334588

Mucosal immunization: Adjuvants and delivery systems

2004

Journal Article

Group A streptococcal vaccine delivery by immunization with a self-adjuvanting M protein-based lipid core peptide construct

Olive, C., Batzloff, M., Horvath, A., Clair, T., Yarwood, P., Toth, I. and Good, M. F. (2004). Group A streptococcal vaccine delivery by immunization with a self-adjuvanting M protein-based lipid core peptide construct. Indian Journal of Medical Research, 119 (Suppl.), 88-94.

Group A streptococcal vaccine delivery by immunization with a self-adjuvanting M protein-based lipid core peptide construct

2004

Journal Article

Toward the development of a synthetic group A streptococcal vaccine of high purity and broad protective coverage

Horvath, Anikó, Olive, Colleen, Karpati, Levente, Sun, H. K., Good, Hsien K. and Toth, Istvan (2004). Toward the development of a synthetic group A streptococcal vaccine of high purity and broad protective coverage. Journal of Medicinal Chemistry, 47 (16), 4100-4104. doi: 10.1021/jm040041w

Toward the development of a synthetic group A streptococcal vaccine of high purity and broad protective coverage

2004

Journal Article

Lipid, sugar and liposaccharide based delivery systems 2

Blanchfield, J. and Toth, I. (2004). Lipid, sugar and liposaccharide based delivery systems 2. Current Medicinal Chemistry, 11 (17), 2375-2382. doi: 10.2174/0929867043364621

Lipid, sugar and liposaccharide based delivery systems 2

2003

Journal Article

Transdermal delivery of a tetrapeptide: Evaluation of passive diffusion

Benson, Heather A. E., Caccetta, Rima, Chen, Yan, Kearns, Philip and Toth, Istvan (2003). Transdermal delivery of a tetrapeptide: Evaluation of passive diffusion. Letters in Peptide Science, 10 (5-6), 615-620. doi: 10.1007/BF02442595

Transdermal delivery of a tetrapeptide: Evaluation of passive diffusion

2003

Journal Article

Development of lipid-core-peptide (LCP) based vaccines for the prevention of the group A streptococcal (GAS) infection

Moyle, P. M., Horvath, A., Olive, C., Good, M. F. and Toth, I. (2003). Development of lipid-core-peptide (LCP) based vaccines for the prevention of the group A streptococcal (GAS) infection. Letters In Peptide Science, 10 (5-6), 605-613. doi: 10.1007/BF02442594

Development of lipid-core-peptide (LCP) based vaccines for the prevention of the group A streptococcal (GAS) infection

2003

Journal Article

Potential of lipid core peptide technology as a novel self-adjuvanting vaccine delivery system for multiple different synthetic peptide immunogens

Olive, Colleen, Batzloff, Michael, Horvath, Aniko, Clair, Timothy, Yarwood, Penny, Toth, Istvan and Good, Michael F. (2003). Potential of lipid core peptide technology as a novel self-adjuvanting vaccine delivery system for multiple different synthetic peptide immunogens. Infection And Immunity, 71 (5), 2373-2383. doi: 10.1128/IAI.71.5.2373-2383.2003

Potential of lipid core peptide technology as a novel self-adjuvanting vaccine delivery system for multiple different synthetic peptide immunogens