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2003

Journal Article

Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of α-conotoxin MII

Blanchfield, J. T., Dutton, J. T., Hogg, R. C., Gallagher, O. P., Craik, D. J., Jones, A., Adams, D. J., Lewis, R. J., Alewood, P. F. and Toth, I. (2003). Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of α-conotoxin MII. Journal of Medicinal Chemistry, 46 (7), 1266-1272. doi: 10.1021/jm020426j

Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of α-conotoxin MII

2003

Journal Article

Biological properties and therapeutic potential of billirubin

McGeary, R. P., Szyczew, A. J. and Toth, I. (2003). Biological properties and therapeutic potential of billirubin. Mini Reviews in Medicinal Chemistry, 3 (3), 253-256. doi: 10.2174/1389557033488213

Biological properties and therapeutic potential of billirubin

2003

Journal Article

Lipid and carbohydrate based adjuvant/carriers in immunology

McGeary, R. P., Olive, C. and Toth, I. (2003). Lipid and carbohydrate based adjuvant/carriers in immunology. Journal of Peptide Science, 9 (7), 405-418. doi: 10.1002/psc.467

Lipid and carbohydrate based adjuvant/carriers in immunology

2003

Journal Article

A new principle for tight junction modulation based on occludin peptides

Tavelin, S., Hashimoto, K., Malkinson, J., Lazorova, L., Toth, I. and Artursson, P. (2003). A new principle for tight junction modulation based on occludin peptides. Molecular Pharmacology, 64 (6), 1530-1540. doi: 10.1124/mol.64.6.1530

A new principle for tight junction modulation based on occludin peptides

2003

Journal Article

Preface

Toth, Istvan (2003). Preface. Mini-Reviews in Medicinal Chemistry, 3 (7), I-I. doi: 10.2174/1389557033487764

Preface

2003

Journal Article

Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failure

Russell, F. D., Meyers, D. E., Galbraith, A., Bett, N., Toth, I., Kearns, P. S. and Molenaar, P. (2003). Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failure. American Journal of Physiology - Heart & Circulatory Physiology, 285 (Oct.2003), H1576-H1581. doi: 10.1152/ajpheart.00217.2003

Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failure

2002

Journal Article

Syntheses of polycationic dendrimers on lipophilic peptide core for complexation and transport of oligonucleotides

Wimmer, Norbert, Marano, Robert J., Kearns, Phillip S., Rakoczy, Elizabeth P. and Toth, Istvan (2002). Syntheses of polycationic dendrimers on lipophilic peptide core for complexation and transport of oligonucleotides. Bioorganic and Medicinal Chemistry Letters, 12 (18), 2635-2637. doi: 10.1016/S0960-894X(02)00511-5

Syntheses of polycationic dendrimers on lipophilic peptide core for complexation and transport of oligonucleotides

2002

Journal Article

Determination of transport in the Caco-2 cell assay of compounds varying in lipophilicity using LC-MS: enhanced transport of Leu-enkephalin analogues

Wong, AK, Ross, BP, Chan, YN, Artursson, P, Lazorova, L, Jones, A and Toth, I (2002). Determination of transport in the Caco-2 cell assay of compounds varying in lipophilicity using LC-MS: enhanced transport of Leu-enkephalin analogues. European Journal of Pharmaceutical Sciences, 16 (3), 113-118. doi: 10.1016/S0928-0987(02)00078-7

Determination of transport in the Caco-2 cell assay of compounds varying in lipophilicity using LC-MS: enhanced transport of Leu-enkephalin analogues

2002

Journal Article

A lipid core peptide construct containing a conserved region determinant of the group a streptococcal M protein elicits heterologous opsonic antibodies

Olive, Colleen, Batzloff, Michael R., Horvath, Aniko, Wong, Allan, Clair, Timothy, Yarwood, Penny, Toth, Istvan and Good, Michael F. (2002). A lipid core peptide construct containing a conserved region determinant of the group a streptococcal M protein elicits heterologous opsonic antibodies. Infection And Immunity, 70 (5), 2734-2738. doi: 10.1128/IAI.70.5.2734-2738.2002

A lipid core peptide construct containing a conserved region determinant of the group a streptococcal M protein elicits heterologous opsonic antibodies

2002

Journal Article

Enhancing the immunogenicity and modulating the fine epitope recognition of antisera to a helical group A streptococcal peptide vaccine candidate from the M protein using lipid-core peptide technology

Hayman, W. A., Toth, I., Flinn, N., Scanlon, M. and Good, M. F. (2002). Enhancing the immunogenicity and modulating the fine epitope recognition of antisera to a helical group A streptococcal peptide vaccine candidate from the M protein using lipid-core peptide technology. Immunology And Cell Biology, 80 (2), 178-187. doi: 10.1046/j.1440-1711.2002.01067.x

Enhancing the immunogenicity and modulating the fine epitope recognition of antisera to a helical group A streptococcal peptide vaccine candidate from the M protein using lipid-core peptide technology

2002

Journal Article

Lipoamino acid-based adjuvant carrier system: Enhanced immunogenicity of group a streptococcal peptide epitopes

Horvath, Aniko, Olive, Colleen, Wong, Allan, Clair, Timothy, Yarwood, Penny, Good, Michael and Toth, Istvan (2002). Lipoamino acid-based adjuvant carrier system: Enhanced immunogenicity of group a streptococcal peptide epitopes. Journal of Medicinal Chemistry, 45 (6), 1387-1390. doi: 10.1021/jm0110441

Lipoamino acid-based adjuvant carrier system: Enhanced immunogenicity of group a streptococcal peptide epitopes

2001

Journal Article

Lipid, sugar and liposaccharide based delivery systems

Wong, A. and Toth, I. (2001). Lipid, sugar and liposaccharide based delivery systems. Current medicinal chemistry, 8 (9), 1123-36.

Lipid, sugar and liposaccharide based delivery systems

2001

Journal Article

The synthesis and structure of an n-terminal dodecanoic acid conjugate of a-conotoxin MII

Blanchfield, Joanne T., Dutton, Julie T., Hogg, R. C., Craik, D. J., Adams, D. J., Lewis, R. J., Alewood, P. and Toth, I. (2001). The synthesis and structure of an n-terminal dodecanoic acid conjugate of a-conotoxin MII. Letters in Peptide Science, 8 (3-5), 235-239. doi: 10.1023/A:1016577832311

The synthesis and structure of an n-terminal dodecanoic acid conjugate of a-conotoxin MII

2001

Journal Article

Towards synthetic vaccines built on carbohydrate cores

McGeary, Ross P., Jablonkai, Istvan and Toth, Istvan (2001). Towards synthetic vaccines built on carbohydrate cores. Letters in Peptide Science, 8 (3-5), 273-276. doi: 10.1007/bf02446528

Towards synthetic vaccines built on carbohydrate cores

2001

Journal Article

A lipophilic adjuvant carrier system for antigenic peptides

Horvath, Aniko, Olive, Colleen, Wong, Allan, Clair, Timothy, Yarwood, Penny, Good, Michael and Toth, Istvan (2001). A lipophilic adjuvant carrier system for antigenic peptides. Letters in Peptide Science, 8 (3-5), 285-288. doi: 10.1007/BF02446530

A lipophilic adjuvant carrier system for antigenic peptides

2001

Journal Article

A novel method for solid-phase synthesis of oligosaccharides using the N-1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl (Dde) linker

Drinnan, Nicholas, West, Michael L., Broadhurst, Max, Kellam, Barrie and Toth, Istvan (2001). A novel method for solid-phase synthesis of oligosaccharides using the N-1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl (Dde) linker. Tetrahedron Letters, 42 (6), 1159-1162. doi: 10.1016/S0040-4039(00)02197-3

A novel method for solid-phase synthesis of oligosaccharides using the N-1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl (Dde) linker

2001

Journal Article

Conversion of glucosamine to galactosamine and allosamine derivatives: Control of inversions of stereochemistry at C-3 and C-4

McGeary, R. P., Wright, K. and Toth, I. (2001). Conversion of glucosamine to galactosamine and allosamine derivatives: Control of inversions of stereochemistry at C-3 and C-4. Journal of Organic Chemistry, 66 (15), 5102-5105. doi: 10.1021/jo010210+

Conversion of glucosamine to galactosamine and allosamine derivatives: Control of inversions of stereochemistry at C-3 and C-4

2001

Journal Article

Technological advances in antigen delivery and synthetic peptide vaccine developmental strategies.

Olive, C., Toth, I. and Jackson, D. (2001). Technological advances in antigen delivery and synthetic peptide vaccine developmental strategies.. Mini Reviews in Medicinal Chemistry, 1 (4), 429-438. doi: 10.2174/1389557013406666

Technological advances in antigen delivery and synthetic peptide vaccine developmental strategies.

2001

Journal Article

Lipophilic methotrexate conjugates with glucose-lipoamino acid moieties: Synthesis and in vitro antitumor activity

Pignatello, R., Vicari, L., Sorrenti, V., Di Giacomo, C., Spampinato, G., Puglisi, G. and Toth, I. (2001). Lipophilic methotrexate conjugates with glucose-lipoamino acid moieties: Synthesis and in vitro antitumor activity. Drug Development Research, 52 (3), 454-461. doi: 10.1002/ddr.1147

Lipophilic methotrexate conjugates with glucose-lipoamino acid moieties: Synthesis and in vitro antitumor activity

2001

Journal Article

Lipid, sugar and liposaccharide based delivery systems

Wong, A. and Toth, I. (2001). Lipid, sugar and liposaccharide based delivery systems. Current Medicinal Chemistry, 8 (9), 1123-1136. doi: 10.2174/0929867013372535

Lipid, sugar and liposaccharide based delivery systems