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Professor David Clark
Professor

David Clark

Email: 

Overview

Background

Professor David A Clark

Royal Brisbane and Women’s Hospital, and University of Queensland, Australia

Prof Clark is a visiting colorectal surgeon at the Royal Brisbane and Women’s Hospital. He qualified from the University of QLD in 1991, trained in surgery in Brisbane, and undertook colorectal fellowships in the United Kingdom. He was admitted as a Fellow of the Royal College of Surgeons at Edinburgh in January 2002.

He is a Professor for the University of QLD and runs a busy clinical practice at the St Vincent's Private Hospital Northside. He has a strong interest in inflammatory bowel disease and the IBD Unit at the RBWH has an active academic program. Prof Clark has presented internationally in the field of IBD and minimally invasive colorectal surgery.

The colorectal unit based at the RBWH has a commitment to education and runs a regular laparoscopic colorectal training course and now supports 3 colorectal fellows and a research co-ordinator. He is a board member of the ANZ Training Board in Colorectal Surgery (ANZTBCRS) and the recent convenor for the Society and Section scientific meetings.

Prof Clark heads the Brisbane Colorectal Reseacrh Unit (CRU) and completed a PhD at the University of Sydney in June 2022. He concurrently supervised 4 PhD candidates through UQ. He is widely published in the fields of minimally invasive surgery and inflammaory bowel disease.

Brisbane is renowned for minimally invasive colorectal surgery and training and teaching are a passion.

Availability

Professor David Clark is:
Available for supervision

Qualifications

  • Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
  • Doctor of Philosophy, University of Sydney
  • Board Member, Australia and New Zealand Training Board in Colorectal Surgery, Australia and New Zealand Training Board in Colorectal Surgery
  • Member, Colorectal Surgical Society of Australia and New Zealand, Colorectal Surgical Society of Australia and New Zealand
  • Fellow, Royal Australasian College of Surgeons, Royal Australasian College of Surgeons
  • Fellow, Royal College of Surgeons of Edinburgh, Royal College of Surgeons of Edinburgh

Research interests

  • Early Surgery for Ileal Crohn's Disease

    Surgery as a therapeutic option vs trial of multiple medical therapies.

  • Surgery for Acute Severe Ulcerative Colitis

    Refining the minimally invasive technique for these acutely unwell patients and optimizing the ultimate restorative procedure.

  • Minimally invasive colorectal surgery

    Regular masterclasses showcasing advances in minimally invasive approaches to colorectal surgery.

  • Modified Kono S anastomosis after ileocolic resection for Crohn's disease

    An RCT out of the RBWH and recruiting 2023.

  • Colorectal cancer organoids for predicting response to chemotherapy

    QIMR research project to collect specimens and enhance the pipeline to grow and test organoids in a clinically actionable timeframe.

Research impacts

Professor Clark's publications in the field of drain fluid biomarkers of anastomotic leak have seen the uptake of the research methodology in numerous centres around the world. Indeed the measurement of drain fluid amylase is an inexpensive and readily availble test that should be the standard of care in the peri-operative period of ileal pouch surgery when a diverting ileostomy is not incorporated. Further development of novel drain fluid biomarkers are under investigation to support the post-operative care in the setting of rectal cancer surgery.

Research in the field of organoids has the potential to translate to precision medicine in a clinically actionable timeframe.

Publications from the colorectal sub-committee in colorectal cancer through the Queensland Cancer Control and Analysis Team (QCCAT) are produced to report on multiple aspects of service delivery and quality throughout Queensland with the goal of enhancing patient outcomes throughout the state.

Works

Search Professor David Clark’s works on UQ eSpace

97 works between 1999 and 2025

61 - 80 of 97 works

2020

Journal Article

Ileal pouch-anal anastomosis for ulcerative colitis: an Australian institution

Lim, Ming Han, Lord, Anton R., Simms, Lisa A., Hannigan, Katherine, Edmundson, Aleksandra, Rickard, Matthew J. F. X., Stitz, Russell, Clark, David A. and Radford-Smith, Graham L. (2020). Ileal pouch-anal anastomosis for ulcerative colitis: an Australian institution. Annals of Coloproctology, 37 (5), 318-325. doi: 10.3393/ac.2020.08.26

Ileal pouch-anal anastomosis for ulcerative colitis: an Australian institution

2020

Journal Article

Anastomotic leak does not affect long-term and longitudinal functional outcomes after ileal pouch surgery for ulcerative colitis when managed aggressively

Yu, J., Clark, D. A., Sidhom, D., Edmundson, A. and Solomon, M. (2020). Anastomotic leak does not affect long-term and longitudinal functional outcomes after ileal pouch surgery for ulcerative colitis when managed aggressively. Techniques in Coloproctology, 24 (12), 1285-1292. doi: 10.1007/s10151-020-02331-5

Anastomotic leak does not affect long-term and longitudinal functional outcomes after ileal pouch surgery for ulcerative colitis when managed aggressively

2020

Journal Article

International expert consensus guidance on indications, implementation and quality measures for transanal total mesorectal excision

Adamina, Michel, Aigner, Felix, Araujo, Sergio, Arezzo, Alberto, Ashamalla, Shady, deBeche-Adams, Teresa, Bell, Stephen, Bemelman, Willem, Brown, Carl, Brunner, Walter, Buchs, Nicolas, Caycedo, Antonio, Chadi, Sami, Sung Chan, Park, Clark, David, Denost, Quentin, D'Hoore, André, Fearnhead, Nicola, Francis, Nader, de Graaf, Eelco, Hasegawa, Suguru, Hayes, Julian, Heriot, Alexander, Houben, Bert, Ito, Masaaki, Katory, Mark, Kleijnen, Jos, Kneist, Werner, Knol, Joep ... The TaTME Guidance Group (2020). International expert consensus guidance on indications, implementation and quality measures for transanal total mesorectal excision. Colorectal Disease, 22 (7), 749-755. doi: 10.1111/codi.15147

International expert consensus guidance on indications, implementation and quality measures for transanal total mesorectal excision

2020

Journal Article

Locoregional recurrences after transanal total mesorectal excision of rectal cancer during the exploration phase: locoregional recurrence in taTME for rectal cancer

Warrier, S. K., Bell, S., Guest, G., Heriot, A., Kong, J. C., Eglinton, T. W., Hayes, J., Merrie, A., Clark, D. and Stevenson, A. (2020). Locoregional recurrences after transanal total mesorectal excision of rectal cancer during the exploration phase: locoregional recurrence in taTME for rectal cancer. British Journal of Surgery, 107 (9), e353-e353. doi: 10.1002/bjs.11753

Locoregional recurrences after transanal total mesorectal excision of rectal cancer during the exploration phase: locoregional recurrence in taTME for rectal cancer

2020

Journal Article

Gastrografin can be detected in ex vivo biological specimens by dual‐energy CT scanning

Clark, David A., Yeoh, Edward, Edmundson, Aleksandra, Pratap, Jit, Snow, Tom, Solomon, Michael and Coucher, John (2020). Gastrografin can be detected in ex vivo biological specimens by dual‐energy CT scanning. Journal of Medical Imaging and Radiation Oncology, 64 (5) 1754-9485.13071, 634-640. doi: 10.1111/1754-9485.13071

Gastrografin can be detected in ex vivo biological specimens by dual‐energy CT scanning

2020

Journal Article

International consensus definition of low anterior resection syndrome

Keane, C., Fearnhead, N. S., Bordeianou, L., Christensen, P., Espin Basany, E., Laurberg, S., Mellgren, A., Messick, C., Orangio, G. R., Verjee, A., Wing, K., Bissett, I., An, V., Bryant, A., Byrne, C., Chen, T., Clark, D., Croft, S., Dinning, P., Gladman, M., Heriot, A., Kariappa, S., Keck, J., Lubowski, D., Khera, A., Kirkwood, K., Petersen, D., Sloots, K., Totten, B. ... on behalf of the LARS International Collaborative Group (2020). International consensus definition of low anterior resection syndrome. Colorectal Disease, 22 (3), 331-341. doi: 10.1111/codi.14957

International consensus definition of low anterior resection syndrome

2020

Journal Article

International consensus definition of low anterior resection syndrome

Keane, Celia, Fearnhead, Nicola S., Bordeianou, Liliana G., Christensen, Peter, Basany, Eloy Espin, Laurberg, Soren, Mellgren, Anders, Messick, Craig, Orangio, Guy R., Verjee, Azmina, Wing, Kirsty, Bissett, Ian P., An,, Bryant, A., Byrne, C., Chen, T., Croft, S., Clark, D., Gladman, M., Heriot, A., Kariappa, S., Keck, J., Lubowski, D., Dinning, P., Khera, A., Kirkwood, K., Petersen, D., Sloots, K., Totten, B. ... on behalf of the LARS International Collaborative Group (2020). International consensus definition of low anterior resection syndrome. ANZ Journal of Surgery, 90 (3), 300-307. doi: 10.1111/ans.15421

International consensus definition of low anterior resection syndrome

2020

Journal Article

International consensus definition of low anterior resection syndrome

Keane, Celia, Fearnhead, Nicola S., Bordeianou, Liliana G., Christensen, Peter, Basany, Eloy Espin, Laurberg, Søren, Mellgren, Anders, Messick, Craig, Orangio, Guy R., Verjee, Azmina, Wing, Kirsty, Bissett, Ian, An, V., Bryant, A., Byrne, C., Chen, T., Croft, S., Clark, D., Gladman, M., Heriot, A., Kariappa, S., Keck, J., Lubowski, D., Dinning, P., Khera, A., Kirkwood, K., Petersen, D., Sloots, K., Totten, B. ... on behalf of the LARS International Collaborative Group (2020). International consensus definition of low anterior resection syndrome. Diseases of the Colon and Rectum, 63 (3), 274-284. doi: 10.1097/DCR.0000000000001583

International consensus definition of low anterior resection syndrome

2019

Journal Article

Implementation science approaches to enhance uptake of complex interventions in surgical settings

Byrnes, Angela, Mudge, Alison and Clark, David (2019). Implementation science approaches to enhance uptake of complex interventions in surgical settings. Australian Health Review, 44 (2), 310-312. doi: 10.1071/ah18193

Implementation science approaches to enhance uptake of complex interventions in surgical settings

2019

Journal Article

Disease-free Survival and Local Recurrence After Laparoscopic-assisted Resection or Open Resection for Rectal Cancer: The Australasian Laparoscopic Cancer of the Rectum Randomized Clinical Trial

Stevenson, Andrew R. L., Solomon, Michael J., Brown, Christopher S. B., Lumley, John W., Hewett, Peter, Clouston, Andrew D., Gebski, Val J., Wilson, Kate, Hague, Wendy, Simes, John, on behalf of the Australasian Gastro-Intestinal Trials Group (AGITG) ALaCaRT investigators and Clark, David (2019). Disease-free Survival and Local Recurrence After Laparoscopic-assisted Resection or Open Resection for Rectal Cancer: The Australasian Laparoscopic Cancer of the Rectum Randomized Clinical Trial. Annals of Surgery, 269 (4), 596-602. doi: 10.1097/SLA.0000000000003021

Disease-free Survival and Local Recurrence After Laparoscopic-assisted Resection or Open Resection for Rectal Cancer: The Australasian Laparoscopic Cancer of the Rectum Randomized Clinical Trial

2019

Journal Article

Drain fluid amylase as a sensitive biomarker for the early detection of anastomotic leakage in ileal pouch surgery

Clark, D. A., Cuda, T., Riddell, A., Radford-Smith, G. and Solomon, M. (2019). Drain fluid amylase as a sensitive biomarker for the early detection of anastomotic leakage in ileal pouch surgery. Colorectal Disease, 21 (4), 460-464. doi: 10.1111/codi.14536

Drain fluid amylase as a sensitive biomarker for the early detection of anastomotic leakage in ileal pouch surgery

2019

Journal Article

Carbon dioxide embolism associated with transanal total mesorectal excision surgery: a report from the international registries

Dickson, Edward A., Penna, Marta, Cunningham, Chris, Ratcliffe, Fiona M., Chantler, Jonathan, Crabtree, Nicholas A., Tuynman, Jurriaan B., Albert, Matthew R., Monson, John R.T., Hompes, Roel, Abdelmoaty, Walaa, Adamina, Michel, Aigner, Felix, Alavi, Karim, Albers, Benjamin, Al Furajii, Hazar, Allison, Andrew, Eduardo, Sergio, Araujo, Alonso, Apostolides, George Y., Arezzo, Alberto, Arnold, Steven J., Aryal, Kamal, Ashamalla, Shady, Ashraf, Shazad, Attaluri, Vikram, Austin, Ralph, Barugo-La, Giuliano, Beggs, Andrew ... Wynn, Greg (2019). Carbon dioxide embolism associated with transanal total mesorectal excision surgery: a report from the international registries. Diseases of the Colon and Rectum, 62 (7), 794-801. doi: 10.1097/DCR.0000000000001410

Carbon dioxide embolism associated with transanal total mesorectal excision surgery: a report from the international registries

2018

Conference Publication

Quality of care and quality of life for Queensland colorectal cancer patients

Dunn, Nathan, Rawson, Neal, Harrington, John, Hansen, John, Prinsloo, Pieter, Clark, David, Taylor, David, Lutton, Nicholas, Doudle, Mark and Theile, David (2018). Quality of care and quality of life for Queensland colorectal cancer patients. HOBOKEN: WILEY.

Quality of care and quality of life for Queensland colorectal cancer patients

2018

Conference Publication

The safety and efficacy of colorectal cancer surgery in Queensland

Dunn, Nathan, Rawson, Neal, Harrington, John, Hansen, John, Prinsloo, Pieter, Clark, David, Taylor, David, Lutton, Nicholas, Doudle, Mark and Theile, David (2018). The safety and efficacy of colorectal cancer surgery in Queensland. HOBOKEN: WILEY.

The safety and efficacy of colorectal cancer surgery in Queensland

2018

Journal Article

The ALCCaS Trial: a randomized controlled trial comparing quality of life following laparoscopic versus open colectomy for colon cancer

McCombie, Andrew M., Frizelle, Frank, Bagshaw, Philip Frederick, Frampton, Chris M., Hewett, Peter J., McMurrick, Paul John, Rieger, Nicholas, Solomon, Michael J., Stevenson, Andrew R., On behalf of the ALCCaS Trial group and Clark, David (2018). The ALCCaS Trial: a randomized controlled trial comparing quality of life following laparoscopic versus open colectomy for colon cancer. Diseases of the Colon and Rectum, 61 (10), 1156-1162. doi: 10.1097/dcr.0000000000001165

The ALCCaS Trial: a randomized controlled trial comparing quality of life following laparoscopic versus open colectomy for colon cancer

2018

Journal Article

Transanal total mesorectal excision for rectal cancer: state of the art

Westwood, David A., Cuda, Tahleesa J., Hamilton, A. E. Ricardo, Clark, David and Stevenson, Andrew R. L. (2018). Transanal total mesorectal excision for rectal cancer: state of the art. Techniques in Coloproctology, 22 (9), 649-655. doi: 10.1007/s10151-018-1844-8

Transanal total mesorectal excision for rectal cancer: state of the art

2018

Conference Publication

Have changes in medical therapy and surgical techniques for the treatment of ulcerative colitis altered post-colectomy outcomes over the past 26 years?

Lim, M. H., Lord, A., Simms, L., Hanigan, K., Edmundson, A., Rickard, M., Stitz, R., Clark, D. and Radford-Smith, G. L. (2018). Have changes in medical therapy and surgical techniques for the treatment of ulcerative colitis altered post-colectomy outcomes over the past 26 years?. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “Gut Matters”, Brisbane, QLD Australia, 8-10 September 2018. Richmond, VIC Australia: John Wiley & Sons.

Have changes in medical therapy and surgical techniques for the treatment of ulcerative colitis altered post-colectomy outcomes over the past 26 years?

2018

Journal Article

Prospective application of an implementation framework to improve postoperative nutrition care processes: evaluation of a mixed methods implementation study

Byrnes, Angela, Young, Adrienne, Mudge, Alison, Banks, Merrilyn, Clark, David and Bauer, Judy (2018). Prospective application of an implementation framework to improve postoperative nutrition care processes: evaluation of a mixed methods implementation study. Nutrition & Dietetics, 75 (4), 353-362. doi: 10.1111/1747-0080.12464

Prospective application of an implementation framework to improve postoperative nutrition care processes: evaluation of a mixed methods implementation study

2018

Journal Article

A case study of ileal metaplasia and neoplasia in a patient with an ileal-rectal anatomosis

Campbell, Beth M., Clark, David, Harvey, James and Reid, Andrew (2018). A case study of ileal metaplasia and neoplasia in a patient with an ileal-rectal anatomosis. Journal of Coloproctology, 38 (2), 151-153. doi: 10.1016/j.jcol.2017.12.006

A case study of ileal metaplasia and neoplasia in a patient with an ileal-rectal anatomosis

2018

Journal Article

An assessment of an Australasian pathway for the introduction of transanal total mesorectal excision (taTME)

Abbott, S. C., Stevenson, A. R. L., Bell, S. W., Clark, D., Merrie, A., Hayes, J., Ganesh, S., Heriot, A. G. and Warrier, S. K. (2018). An assessment of an Australasian pathway for the introduction of transanal total mesorectal excision (taTME). Colorectal Disease, 20 (1), O1-O6. doi: 10.1111/codi.13964

An assessment of an Australasian pathway for the introduction of transanal total mesorectal excision (taTME)

Supervision

Availability

Professor David Clark is:
Available for supervision

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Available projects

  • Ileostomy app to reduce readmission with dehydration

Supervision history

Current supervision

  • Doctor Philosophy

    Improving the management decisions for patients diagnosed with a colorectal malignant polyp

    Associate Advisor

  • Doctor Philosophy

    Reducing post-operative Crohn's disease recurrence

    Associate Advisor

    Other advisors: Associate Professor Jakob Begun, Dr Rabina Giri

  • Doctor Philosophy

    Personalised Medicine for Colorectal Cancer

    Associate Advisor

    Other advisors: Honorary Professor Vicki Whitehall

  • Doctor Philosophy

    Improving Immunotherapy Efficacy for Colorectal Cancer

    Associate Advisor

    Other advisors: Honorary Professor Vicki Whitehall

  • Doctor Philosophy

    Novel Theranostic Targets for Colorectal Cancer

    Associate Advisor

  • Doctor Philosophy

    Novel theranostic targets for metastatic colorectal cancer

    Associate Advisor

  • Doctor Philosophy

    Improving the management decisions for patients diagnosed with a colorectal malignant polyp

    Associate Advisor

Completed supervision

Media

Enquiries

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communications@uq.edu.au