
Overview
Background
Professor David A Clark
Royal Brisbane and Women’s Hospital, and University of Queensland, Australia
Prof Clark is a visiting colorectal surgeon at the Royal Brisbane and Women’s Hospital. He qualified from the University of QLD in 1991, trained in surgery in Brisbane, and undertook colorectal fellowships in the United Kingdom. He was admitted as a Fellow of the Royal College of Surgeons at Edinburgh in January 2002.
He is a Professor for the University of QLD and runs a busy clinical practice at the St Vincent's Private Hospital Northside. He has a strong interest in inflammatory bowel disease and the IBD Unit at the RBWH has an active academic program. Prof Clark has presented internationally in the field of IBD and minimally invasive colorectal surgery.
The colorectal unit based at the RBWH has a commitment to education and runs a regular laparoscopic colorectal training course and now supports 3 colorectal fellows and a research co-ordinator. He is a board member of the ANZ Training Board in Colorectal Surgery (ANZTBCRS) and the recent convenor for the Society and Section scientific meetings.
Prof Clark heads the Brisbane Colorectal Reseacrh Unit (CRU) and completed a PhD at the University of Sydney in June 2022. He concurrently supervised 4 PhD candidates through UQ. He is widely published in the fields of minimally invasive surgery and inflammaory bowel disease.
Brisbane is renowned for minimally invasive colorectal surgery and training and teaching are a passion.
Availability
- Professor David Clark is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
- Doctor of Philosophy, University of Sydney
- Board Member, Australia and New Zealand Training Board in Colorectal Surgery, Australia and New Zealand Training Board in Colorectal Surgery
- Member, Colorectal Surgical Society of Australia and New Zealand, Colorectal Surgical Society of Australia and New Zealand
- Fellow, Royal Australasian College of Surgeons, Royal Australasian College of Surgeons
- Fellow, Royal College of Surgeons of Edinburgh, Royal College of Surgeons of Edinburgh
Research interests
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Early Surgery for Ileal Crohn's Disease
Surgery as a therapeutic option vs trial of multiple medical therapies.
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Surgery for Acute Severe Ulcerative Colitis
Refining the minimally invasive technique for these acutely unwell patients and optimizing the ultimate restorative procedure.
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Minimally invasive colorectal surgery
Regular masterclasses showcasing advances in minimally invasive approaches to colorectal surgery.
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Modified Kono S anastomosis after ileocolic resection for Crohn's disease
An RCT out of the RBWH and recruiting 2023.
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Colorectal cancer organoids for predicting response to chemotherapy
QIMR research project to collect specimens and enhance the pipeline to grow and test organoids in a clinically actionable timeframe.
Research impacts
Professor Clark's publications in the field of drain fluid biomarkers of anastomotic leak have seen the uptake of the research methodology in numerous centres around the world. Indeed the measurement of drain fluid amylase is an inexpensive and readily availble test that should be the standard of care in the peri-operative period of ileal pouch surgery when a diverting ileostomy is not incorporated. Further development of novel drain fluid biomarkers are under investigation to support the post-operative care in the setting of rectal cancer surgery.
Research in the field of organoids has the potential to translate to precision medicine in a clinically actionable timeframe.
Publications from the colorectal sub-committee in colorectal cancer through the Queensland Cancer Control and Analysis Team (QCCAT) are produced to report on multiple aspects of service delivery and quality throughout Queensland with the goal of enhancing patient outcomes throughout the state.
Works
Search Professor David Clark’s works on UQ eSpace
2023
Journal Article
In comparison with polypectomy, colorectal resection is associated with improved survival for patients diagnosed with malignant polyps
Zammit, Andrew P., Hooper, John D., Brown, Ian, Clark, David A. and Riddell, Andrew D. (2023). In comparison with polypectomy, colorectal resection is associated with improved survival for patients diagnosed with malignant polyps. Colorectal Disease, 25 (2), 261-271. doi: 10.1111/codi.16369
2023
Journal Article
Malignant polyps in the COVID ‐19 era: a population‐based analysis
Zammit, Andrew P., Brown, Ian, Hooper, John D., Clark, David A. and Riddell, Andrew D. (2023). Malignant polyps in the COVID ‐19 era: a population‐based analysis. ANZ Journal of Surgery, 93 (4), 932-938. doi: 10.1111/ans.18253
2023
Journal Article
Renal dysfunction occurs following ileostomy formation and is independent of readmission
Panizza, John, Swee, Yan Jing Sherrie, Edmundson, Aleks and Clark, David (2023). Renal dysfunction occurs following ileostomy formation and is independent of readmission. ANZ Journal of Surgery, 93 (3), 622-628. doi: 10.1111/ans.18254
2023
Journal Article
Management of high and low risk malignant polyps – a population wide analysis
Zammit, Andrew P., Panahi, Seyed E., Brown, Ian, Hooper, John D., Clark, David A. and Riddell, Andrew D. (2023). Management of high and low risk malignant polyps – a population wide analysis. Colorectal Disease, 25 (1), 66-74. doi: 10.1111/codi.16328
2022
Journal Article
Recurrent pouch volvulus treated with robotic ventral graft pouch‐pexy
Zammit, Andrew P., Srinath, Havish, Warner, Ross, Mor, Isabella and Clark, David A. (2022). Recurrent pouch volvulus treated with robotic ventral graft pouch‐pexy. ANZ Journal of Surgery, 93 (5), 1386-1387. doi: 10.1111/ans.18197
2022
Journal Article
Time for an Australian and New Zealand randomized controlled trial to study the modified Kono S anastomosis
Clark, David A., Smith, Nicholas, Clark, Imogen, Giddings, Hugh and Rajan, Ruben (2022). Time for an Australian and New Zealand randomized controlled trial to study the modified Kono S anastomosis. ANZ Journal of Surgery, 92 (12), 3132-3134. doi: 10.1111/ans.17991
2022
Journal Article
Poor agreement among Australian and New Zealand clinicians is a barrier to implementation of early post‐operative feeding following colorectal surgery
Byrnes, Angela, Clark, David, Glen, Kate and Young, Adrienne (2022). Poor agreement among Australian and New Zealand clinicians is a barrier to implementation of early post‐operative feeding following colorectal surgery. ANZ Journal of Surgery, 93 (1-2), 17-18. doi: 10.1111/ans.18007
2022
Journal Article
Diminishing lengths of subsequent bowel resections in the surgical management of ileal Crohn's disease
Maher, Declan, Ting, Pascallina, Edmundson, Aleksandra, Cuda, Tahleesa J. and Clark, David A. (2022). Diminishing lengths of subsequent bowel resections in the surgical management of ileal Crohn's disease. ANZ Journal of Surgery, 92 (11), 2921-2925. doi: 10.1111/ans.18047
2022
Journal Article
Timing of surveillance colonoscopy following malignant colorectal polypectomy in Queensland
Zammit, Andrew P., Brown, Ian, Hooper, John D., Clark, David A. and Riddell, Andrew D. (2022). Timing of surveillance colonoscopy following malignant colorectal polypectomy in Queensland. ANZ Journal of Surgery, 93 (3), 606-611. doi: 10.1111/ans.18069
2022
Journal Article
International expert opinion on optimal treatment of anastomotic leakage after rectal cancer resection: a case-vignette study
Talboom, Kevin, Greijdanus, Nynke G., van Workum, Frans, Ubels, Sander, Rosman, Camiel, Hompes, Roel, de Wilt, Johannes H. W., Tanis, Pieter J., the TENTACLE-Rectum working group and Clark, David (2022). International expert opinion on optimal treatment of anastomotic leakage after rectal cancer resection: a case-vignette study. International Journal of Colorectal Disease, 37 (9), 2049-2059. doi: 10.1007/s00384-022-04240-5
2022
Conference Publication
EP-369 examining EphA2 expression in colorectal cancer
Lyons, Nicholas, Hooper, John, Kryza, Thomas, Clark, David and Riddell, Andrew (2022). EP-369 examining EphA2 expression in colorectal cancer. Association of Surgeons of Great Britain and Ireland Annual Congress, Liverpool, United Kingdom, 2022. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/bjs/znac245.094
2022
Conference Publication
Intraoperative identification of colorectal cancer lesions using indocyanine green labelled antibodies in preclinical murine models
Lyons, Nicholas, Hooper, John, Clark, David, Riddell, Andrew and Kryza, Thomas (2022). Intraoperative identification of colorectal cancer lesions using indocyanine green labelled antibodies in preclinical murine models. Association of Surgeons of Great Britain and Ireland, Annual Congress, Liverpool, United Kingdom, 3-5 May 2022. Oxford, United Kingdom: Oxford University Press . doi: 10.1093/bjs/znac245.093
2022
Journal Article
A population‐based study of the management of rectal malignant polyps and the use of trans‐anal surgery
Zammit, Andrew P., Brown, Ian, Hooper, John D., Clark, David A. and Riddell, Andrew D. (2022). A population‐based study of the management of rectal malignant polyps and the use of trans‐anal surgery. ANZ Journal of Surgery, 92 (11), 2949-2955. doi: 10.1111/ans.17917
2022
Journal Article
Teardrop Flap for Perianal Lesion
Mirza, Wasif, Rajan, Ruben, Petersson, Josefin, Kulendran, Krish, Ratinam, Ratheesraj and Clark, David (2022). Teardrop Flap for Perianal Lesion. Colorectal Disease, 24 (12), 1630-1631. doi: 10.1111/codi.16251
2022
Journal Article
Current management of large bowel obstruction: a narrative review
Rajan, Ruben and Clark, David A. (2022). Current management of large bowel obstruction: a narrative review. Annals of Laparoscopic and Endoscopic Surgery, 7 23, 1-14. doi: 10.21037/ales-21-45
2022
Journal Article
Post-Operative Functional Outcomes in Early Age Onset Rectal Cancer
REACCT Collaborative and Clark, David (2022). Post-Operative Functional Outcomes in Early Age Onset Rectal Cancer. Frontiers in Oncology, 12 868359. doi: 10.3389/fonc.2022.868359
2022
Journal Article
Impact of microsatellite status in early-onset colonic cancer
Zaborowski, Alexandra M., Abdile, Ahmed, Adamina, Michel, Aigner, Felix, D'Allens, Laura, Allmer, Caterina, Alvarez, Andrea, Anula, Rocio, Andric, Mihailo, Atallah, Sam, Bach, Simon, Bala, Miklosh, Barussaud, Marie, Bausys, Augustinas, Beggs, Andrew, Bellolio, Felipe, Bennett, Melissa-Rose, Bevan, Vicki, Biondo, Sebastiano, Bislenghi, Gabriele, Bludau, Marc, Brouwer, Nelleke, Brown, Carl, Bruns, Christiane, Buchanan, Daniel D., Buchwald, Pamela, Burger, Jacobus W. A., Burlov, Nikita, Campanelli, Michela ... REACCT Collaborative (2022). Impact of microsatellite status in early-onset colonic cancer. British Journal of Surgery, 109 (7), 632-636. doi: 10.1093/bjs/znac108
2022
Journal Article
A development study of drain fluid gastrografin as a biomarker of anastomotic leak
Clark, David A., Yeoh, Edward, Edmundson, Aleksandra, Harris, Craig, Stevenson, Andrew, Steffens, Daniel and Solomon, Michael (2022). A development study of drain fluid gastrografin as a biomarker of anastomotic leak. Annals of Coloproctology, 38 (2), 124-132. doi: 10.3393/ac.2020.12.24
2022
Journal Article
Risk taking propensity: nurse, surgeon and patient preferences for diverting ileostomy
Mackay, Ian, Clark, David A., Nicholson, James, Edmundson, Aleks, Steffens, Daniel and Solomon, Michael (2022). Risk taking propensity: nurse, surgeon and patient preferences for diverting ileostomy. Colorectal Disease, 24 (9), 1073-1079. doi: 10.1111/codi.16149
2022
Journal Article
Patient and pathological predictors of management strategy for malignant polyps following polypectomy: a systematic review and meta-analysis
Zammit, Andrew P., Lyons, Nicholas J., Chatfield, Mark D., Hooper, John D., Brown, Ian, Clark, David A. and Riddell, Andrew D. (2022). Patient and pathological predictors of management strategy for malignant polyps following polypectomy: a systematic review and meta-analysis. International Journal of Colorectal Disease, 37 (5), 1035-1047. doi: 10.1007/s00384-022-04142-6
Supervision
Availability
- Professor David Clark is:
- Available for supervision
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Available projects
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Ileostomy app to reduce readmission with dehydration
Supervision history
Current supervision
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Doctor Philosophy
Novel theranostic targets for metastatic colorectal cancer
Associate Advisor
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Doctor Philosophy
Novel Theranostic Targets for Colorectal Cancer
Associate Advisor
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Doctor Philosophy
Improving the management decisions for patients diagnosed with a colorectal malignant polyp
Associate Advisor
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Doctor Philosophy
Reducing post-operative Crohn's disease recurrence
Associate Advisor
Other advisors: Associate Professor Jakob Begun, Dr Rabina Giri
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Doctor Philosophy
Improving the management decisions for patients diagnosed with a colorectal malignant polyp
Associate Advisor
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Doctor Philosophy
Personalised Medicine for Colorectal Cancer
Associate Advisor
Other advisors: Honorary Professor Vicki Whitehall
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Doctor Philosophy
Improving Immunotherapy Efficacy for Colorectal Cancer
Associate Advisor
Other advisors: Honorary Professor Vicki Whitehall
Completed supervision
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2025
Doctor Philosophy
Improving the management decisions for patients diagnosed with a colorectal malignant polyp
Associate Advisor
Media
Enquiries
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