![Professor David Clark](/sites/default/files/profiles/1294.jpeg)
Overview
Background
Professor David A Clark
Royal Brisbane and Women’s Hospital, and University of Queensland, Australia
Prof Clark is a visiting colorectal surgeon at the Royal Brisbane and Women’s Hospital. He qualified from the University of QLD in 1991, trained in surgery in Brisbane, and undertook colorectal fellowships in the United Kingdom. He was admitted as a Fellow of the Royal College of Surgeons at Edinburgh in January 2002.
He is a Professor for the University of QLD and runs a busy clinical practice at the St Vincent's Private Hospital Northside. He has a strong interest in inflammatory bowel disease and the IBD Unit at the RBWH has an active academic program. Prof Clark has presented internationally in the field of IBD and minimally invasive colorectal surgery.
The colorectal unit based at the RBWH has a commitment to education and runs a regular laparoscopic colorectal training course and now supports 3 colorectal fellows and a research co-ordinator. He is a board member of the ANZ Training Board in Colorectal Surgery (ANZTBCRS) and the recent convenor for the Society and Section scientific meetings.
Prof Clark heads the Brisbane Colorectal Reseacrh Unit (CRU) and completed a PhD at the University of Sydney in June 2022. He concurrently supervised 4 PhD candidates through UQ. He is widely published in the fields of minimally invasive surgery and inflammaory bowel disease.
Brisbane is renowned for minimally invasive colorectal surgery and training and teaching are a passion.
Availability
- Professor David Clark is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
- Doctor of Philosophy, University of Sydney
- Board Member, Australia and New Zealand Training Board in Colorectal Surgery, Australia and New Zealand Training Board in Colorectal Surgery
- Member, Colorectal Surgical Society of Australia and New Zealand, Colorectal Surgical Society of Australia and New Zealand
- Fellow, Royal Australasian College of Surgeons, Royal Australasian College of Surgeons
- Fellow, Royal College of Surgeons of Edinburgh, Royal College of Surgeons of Edinburgh
Research interests
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Early Surgery for Ileal Crohn's Disease
Surgery as a therapeutic option vs trial of multiple medical therapies.
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Surgery for Acute Severe Ulcerative Colitis
Refining the minimally invasive technique for these acutely unwell patients and optimizing the ultimate restorative procedure.
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Minimally invasive colorectal surgery
Regular masterclasses showcasing advances in minimally invasive approaches to colorectal surgery.
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Modified Kono S anastomosis after ileocolic resection for Crohn's disease
An RCT out of the RBWH and recruiting 2023.
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Colorectal cancer organoids for predicting response to chemotherapy
QIMR research project to collect specimens and enhance the pipeline to grow and test organoids in a clinically actionable timeframe.
Research impacts
Professor Clark's publications in the field of drain fluid biomarkers of anastomotic leak have seen the uptake of the research methodology in numerous centres around the world. Indeed the measurement of drain fluid amylase is an inexpensive and readily availble test that should be the standard of care in the peri-operative period of ileal pouch surgery when a diverting ileostomy is not incorporated. Further development of novel drain fluid biomarkers are under investigation to support the post-operative care in the setting of rectal cancer surgery.
Research in the field of organoids has the potential to translate to precision medicine in a clinically actionable timeframe.
Publications from the colorectal sub-committee in colorectal cancer through the Queensland Cancer Control and Analysis Team (QCCAT) are produced to report on multiple aspects of service delivery and quality throughout Queensland with the goal of enhancing patient outcomes throughout the state.
Works
Search Professor David Clark’s works on UQ eSpace
2022
Journal Article
Timing of surveillance colonoscopy following malignant colorectal polypectomy in Queensland
Zammit, Andrew P., Brown, Ian, Hooper, John D., Clark, David A. and Riddell, Andrew D. (2022). Timing of surveillance colonoscopy following malignant colorectal polypectomy in Queensland. ANZ Journal of Surgery, 93 (3), 606-611. doi: 10.1111/ans.18069
2022
Journal Article
International expert opinion on optimal treatment of anastomotic leakage after rectal cancer resection: a case-vignette study
Talboom, Kevin, Greijdanus, Nynke G., van Workum, Frans, Ubels, Sander, Rosman, Camiel, Hompes, Roel, de Wilt, Johannes H. W., Tanis, Pieter J., the TENTACLE-Rectum working group and Clark, David (2022). International expert opinion on optimal treatment of anastomotic leakage after rectal cancer resection: a case-vignette study. International Journal of Colorectal Disease, 37 (9), 2049-2059. doi: 10.1007/s00384-022-04240-5
2022
Conference Publication
EP-369 examining EphA2 expression in colorectal cancer
Lyons, Nicholas, Hooper, John, Kryza, Thomas, Clark, David and Riddell, Andrew (2022). EP-369 examining EphA2 expression in colorectal cancer. Association of Surgeons of Great Britain and Ireland Annual Congress, Liverpool, United Kingdom, 2022. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/bjs/znac245.094
2022
Conference Publication
Intraoperative identification of colorectal cancer lesions using indocyanine green labelled antibodies in preclinical murine models
Lyons, Nicholas, Hooper, John, Clark, David, Riddell, Andrew and Kryza, Thomas (2022). Intraoperative identification of colorectal cancer lesions using indocyanine green labelled antibodies in preclinical murine models. Association of Surgeons of Great Britain and Ireland, Annual Congress, Liverpool, United Kingdom, 3-5 May 2022. Oxford, United Kingdom: Oxford University Press . doi: 10.1093/bjs/znac245.093
2022
Journal Article
A population‐based study of the management of rectal malignant polyps and the use of trans‐anal surgery
Zammit, Andrew P., Brown, Ian, Hooper, John D., Clark, David A. and Riddell, Andrew D. (2022). A population‐based study of the management of rectal malignant polyps and the use of trans‐anal surgery. ANZ Journal of Surgery, 92 (11), 2949-2955. doi: 10.1111/ans.17917
2022
Journal Article
Teardrop Flap for Perianal Lesion
Mirza, Wasif, Rajan, Ruben, Petersson, Josefin, Kulendran, Krish, Ratinam, Ratheesraj and Clark, David (2022). Teardrop Flap for Perianal Lesion. Colorectal Disease, 24 (12), 1630-1631. doi: 10.1111/codi.16251
2022
Journal Article
Current management of large bowel obstruction: a narrative review
Rajan, Ruben and Clark, David A. (2022). Current management of large bowel obstruction: a narrative review. Annals of Laparoscopic and Endoscopic Surgery, 7 23, 1-14. doi: 10.21037/ales-21-45
2022
Journal Article
Post-Operative Functional Outcomes in Early Age Onset Rectal Cancer
REACCT Collaborative and Clark, David (2022). Post-Operative Functional Outcomes in Early Age Onset Rectal Cancer. Frontiers in Oncology, 12 868359. doi: 10.3389/fonc.2022.868359
2022
Journal Article
Impact of microsatellite status in early-onset colonic cancer
Zaborowski, Alexandra M., Abdile, Ahmed, Adamina, Michel, Aigner, Felix, D'Allens, Laura, Allmer, Caterina, Alvarez, Andrea, Anula, Rocio, Andric, Mihailo, Atallah, Sam, Bach, Simon, Bala, Miklosh, Barussaud, Marie, Bausys, Augustinas, Beggs, Andrew, Bellolio, Felipe, Bennett, Melissa-Rose, Bevan, Vicki, Biondo, Sebastiano, Bislenghi, Gabriele, Bludau, Marc, Brouwer, Nelleke, Brown, Carl, Bruns, Christiane, Buchanan, Daniel D., Buchwald, Pamela, Burger, Jacobus W. A., Burlov, Nikita, Campanelli, Michela ... REACCT Collaborative (2022). Impact of microsatellite status in early-onset colonic cancer. British Journal of Surgery, 109 (7), 632-636. doi: 10.1093/bjs/znac108
2022
Journal Article
A development study of drain fluid gastrografin as a biomarker of anastomotic leak
Clark, David A., Yeoh, Edward, Edmundson, Aleksandra, Harris, Craig, Stevenson, Andrew, Steffens, Daniel and Solomon, Michael (2022). A development study of drain fluid gastrografin as a biomarker of anastomotic leak. Annals of Coloproctology, 38 (2), 124-132. doi: 10.3393/ac.2020.12.24
2022
Journal Article
Risk taking propensity: nurse, surgeon and patient preferences for diverting ileostomy
Mackay, Ian, Clark, David A., Nicholson, James, Edmundson, Aleks, Steffens, Daniel and Solomon, Michael (2022). Risk taking propensity: nurse, surgeon and patient preferences for diverting ileostomy. Colorectal Disease, 24 (9), 1073-1079. doi: 10.1111/codi.16149
2022
Journal Article
Patient and pathological predictors of management strategy for malignant polyps following polypectomy: a systematic review and meta-analysis
Zammit, Andrew P., Lyons, Nicholas J., Chatfield, Mark D., Hooper, John D., Brown, Ian, Clark, David A. and Riddell, Andrew D. (2022). Patient and pathological predictors of management strategy for malignant polyps following polypectomy: a systematic review and meta-analysis. International Journal of Colorectal Disease, 37 (5), 1035-1047. doi: 10.1007/s00384-022-04142-6
2022
Journal Article
Surgical management and long‐term functional outcomes after anastomotic leak in patients undergoing minimally invasive restorative rectal resection and without a diverting ileostomy
McGiffin, Tony, Clark, David A., Edmundson, Aleks, Steffens, Daniel, Stevenson, Andrew and Solomon, Michael (2022). Surgical management and long‐term functional outcomes after anastomotic leak in patients undergoing minimally invasive restorative rectal resection and without a diverting ileostomy. ANZ Journal of Surgery, 92 (4), 806-812. doi: 10.1111/ans.17475
2022
Journal Article
Drain fluid amylase as a biomarker for the detection of anastomotic leakage after rectal resection without a diverting ileostomy
Clark, David A., Edmundson, Aleksandra, Steffens, Daniel, Harris, Craig, Stevenson, Andrew and Solomon, Michael (2022). Drain fluid amylase as a biomarker for the detection of anastomotic leakage after rectal resection without a diverting ileostomy. ANZ Journal of Surgery, 92 (4), 813-818. doi: 10.1111/ans.17461
2022
Journal Article
Multicenter Study of Drain Fluid Amylase as a Biomarker for the Detection of Anastomotic Leakage After Ileal Pouch Surgery Without a Diverting Ileostomy
Clark, David A., Edmundson, Aleksandra, Steffens, Daniel, Radford-Smith, Graham and Solomon, Michael (2022). Multicenter Study of Drain Fluid Amylase as a Biomarker for the Detection of Anastomotic Leakage After Ileal Pouch Surgery Without a Diverting Ileostomy. Diseases of the Colon & Rectum, 65 (11), 1335-1341. doi: 10.1097/dcr.0000000000002376
2022
Journal Article
Microsatellite instability in young patients with rectal cancer: molecular findings and treatment response
Zaborowski, Alexandra M., Abdile, Ahmed, Adamina, Michel, Aigner, Felix, D'Allens, Laura, Allmer, Caterina, Anula, Rocio, Andric, Mihailo, Atallah, Sam, Bach, Simon, Bala, Miklosh, Barussaud, Marie, Bausys, Augustinas, Beggs, Andrew, Bellolio, Felipe, Bennett, Melissa-Rose, Berdinskikh, Anton, Bevan, Vicki, Biondo, Sebastiano, Bislenghi, Gabriele, Bludau, Marc, Brouwer, Nelleke, Brown, Carl, Bruns, Christiane, Buchanan, Daniel D., Buchwald, Pamela, Burger, Jacobus W. A., Burlov, Nikita, Campanelli, Michela ... Winter, Des C. (2022). Microsatellite instability in young patients with rectal cancer: molecular findings and treatment response. British Journal of Surgery, 109 (3), 251-255. doi: 10.1093/bjs/znab437
2022
Journal Article
Ileal Crohn's disease fistulating into a Meckel's diverticulum
Zammit, Andrew Philip, Miller, Gregory, Satchwell, Joshua and Clark, David (2022). Ileal Crohn's disease fistulating into a Meckel's diverticulum. ANZ Journal of Surgery, 92 (11), 3103-3104. doi: 10.1111/ans.17572
2022
Journal Article
The National Aeronautics and Space Administration-task load index: NASA-TLX: evaluation of its use in surgery
Bell, Stephen W., Kong, Joseph C. H., Clark, David A., Carne, Peter, Skinner, Stewart, Pillinger, Stephen, Burton, Paul and Brown, Wendy (2022). The National Aeronautics and Space Administration-task load index: NASA-TLX: evaluation of its use in surgery. ANZ Journal of Surgery, 92 (11), 3022-3028. doi: 10.1111/ans.17830
2022
Journal Article
Does an ileostomy cover the surgeon or the anastomosis?
Clark, David A., Stevenson, Andrew, Lumley, John, Petersen, Damien, Harris, Craig, Steffens, Daniel and Solomon, Michael (2022). Does an ileostomy cover the surgeon or the anastomosis?. ANZ Journal of Surgery, 92 (1-2), 19-20. doi: 10.1111/ans.17364
2021
Journal Article
Incisional hernia following ileostomy closure: who's at risk? The Gold Coast experience
Bloomfield, Ian, Dobson, Benjamin, Von Papen, Michael and Clark, David (2021). Incisional hernia following ileostomy closure: who's at risk? The Gold Coast experience. ANZ Journal of Surgery, 92 (1-2), 146-150. doi: 10.1111/ans.17359
Supervision
Availability
- Professor David Clark is:
- Available for supervision
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Available projects
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Ileostomy app to reduce readmission with dehydration
Supervision history
Current supervision
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Doctor Philosophy
Improving the management decisions for patients diagnosed with a colorectal malignant polyp
Associate Advisor
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Doctor Philosophy
Reducing post-operative Crohn's disease recurrence
Associate Advisor
Other advisors: Associate Professor Jakob Begun
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Doctor Philosophy
Improving Immunotherapy Efficacy for Colorectal Cancer
Associate Advisor
Other advisors: Honorary Professor Vicki Whitehall
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Doctor Philosophy
Personalised Medicine for Colorectal Cancer
Associate Advisor
Other advisors: Honorary Professor Vicki Whitehall
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Doctor Philosophy
Novel theranostic targets for metastatic colorectal cancer
Associate Advisor
Other advisors: Honorary Professor John Hooper
Media
Enquiries
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