
Overview
Background
Prof Nestor joined the Queensland Brain Institute in October/2017 and has a conjoint appointment as a cognitive neurologist at Mater Misericordiae Ltd (Mater Hospital).
His particular interests include understanding the earliest stages of Alzheimer's disease (i.e. before dementia is established); atypical forms of dementia with a particular focus on primary progressive aphasia and dementias related to Parkinson's and Lewy body diseases; and improving differential diagnosis between the major categories of neurodegenerative diseases.
He works on development of neuropsychological tests of cognition, both to accurately track change over time and improve diagnostic accuracy between the major diseases causing dementia. He also uses multi-modal imaging (magnetic resonance imaging [MRI] and positron emission tomography [PET]) to understand the sequence of events occurring in degenerative brain diseases (particularly Alzheimer's disease, frontotemporal dementia, Parkinson's disease, motor neuron disease [ALS], progressive supranuclear palsy [PSP] and corticobasal degeneration [CBD]) and identify novel biomarkers. A major focus of his is on developing novel approaches to MR imaging for single subject pathological diagnoses that can be exported into the everyday clinical setting; recent examples include diffusion tensor imaging to identify PSP and CBD (Sajjadi et al, 2013) and quantitative susceptibility mapping in Parkinson's disease (Acosta-Cabornero et al, 2013).
Availability
- Professor Peter Nestor is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, University of Melbourne
- Doctor of Philosophy, University of Cambridge
Research interests
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Cognitive neurology
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frontotemporal lobar degeneration
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progressive aphasia
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Alzheimer's disease
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Neurodegenerative diseases
Works
Search Professor Peter Nestor’s works on UQ eSpace
2019
Journal Article
Differential effects of Down's syndrome and Alzheimer's neuropathology on default mode connectivity
Wilson, Liam R., Vatansever, Deniz, Annus, Tiina, Williams, Guy B., Hong, Young T., Fryer, Tim D., Nestor, Peter J., Holland, Anthony J. and Zaman, Shahid H. (2019). Differential effects of Down's syndrome and Alzheimer's neuropathology on default mode connectivity. Human Brain Mapping, 40 (15) hbm.24720, 4551-4563. doi: 10.1002/hbm.24720
2019
Journal Article
Delineating the topography of amyloid-associated cortical atrophy in Down syndrome
Mak, Elijah, Padilla, Concepcion, Annus, Tiina, Wilson, Liam R., Hong, Young T., Fryer, Tim D., Coles, Jonathan P., Aigbirhio, Franklin I., Menon, David K., Nestor, Peter J., Zaman, Shahid H. and Holland, Anthony J. (2019). Delineating the topography of amyloid-associated cortical atrophy in Down syndrome. Neurobiology of Aging, 80, 196-202. doi: 10.1016/j.neurobiolaging.2019.02.018
2019
Journal Article
The atrophy pattern in Alzheimer-related PPA is more widespread than that of the frontotemporal lobar degeneration associated variants
Preiß, Daniel, Billette, Ornella V., Schneider, Anja, Spotorno, Nicola and Nestor, Peter J. (2019). The atrophy pattern in Alzheimer-related PPA is more widespread than that of the frontotemporal lobar degeneration associated variants. NeuroImage: Clinical, 24 101994, 101994. doi: 10.1016/j.nicl.2019.101994
2019
Journal Article
Toward in vivo determination of peripheral nervous system immune activity in amyotrophic lateral sclerosis
Schreiber, Stefanie, Schreiber, Frank, Garz, Cornelia, Debska-Vielhaber, Grazyna, Assmann, Anne, Perosa, Valentina, Petri, Susanne, Dengler, Reinhard, Nestor, Peter and Vielhaber, Stefan (2019). Toward in vivo determination of peripheral nervous system immune activity in amyotrophic lateral sclerosis. Muscle and Nerve, 59 (5), 567-576. doi: 10.1002/mus.26444
2019
Journal Article
The BDNF Val66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer’s disease
Franzmeier, Nicolai, Ren, Jinyi, Damm, Alexander, Monté-Rubio, Gemma, Boada, Mercè, Ruiz, Agustín, Ramirez, Alfredo, Jessen, Frank, Düzel, Emrah, Rodríguez Gómez, Octavio, Benzinger, Tammie, Goate, Alison, Karch, Celeste M., Fagan, Anne M., McDade, Eric, Buerger, Katharina, Levin, Johannes, Duering, Marco, Dichgans, Martin, Suárez-Calvet, Marc, Haass, Christian, Gordon, Brian A., Lim, Yen Ying, Masters, Colin L., Janowitz, Daniel, Catak, Cihan, Wolfsgruber, Steffen, Wagner, Michael, Milz, Esther ... Ewers, Michael (2019). The BDNF Val66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer’s disease. Molecular Psychiatry, 26 (2), 614-628. doi: 10.1038/s41380-019-0404-6
2019
Journal Article
The concept of regularization: resolving the problem of surface dyslexia in semantic variant primary progressive aphasia across different languages
Billette, Ornella V., Preib, Daniel and Nestor, Peter J. (2019). The concept of regularization: resolving the problem of surface dyslexia in semantic variant primary progressive aphasia across different languages. Neuropsychology, 34 (3), 298-307. doi: 10.1037/neu0000611
2018
Journal Article
Significance of CSF NfL and tau in ALS
Schreiber, Stefanie, Spotorno, Nicola, Schreiber, Frank, Acosta-Cabronero, Julio, Kaufmann, Jörn, Machts, Judith, Debska-Vielhaber, Grazyna, Garz, Cornelia, Bittner, Daniel, Hensiek, Nathalie, Dengler, Reinhard, Petri, Susanne, Nestor, Peter J. and Vielhaber, Stefan (2018). Significance of CSF NfL and tau in ALS. Journal of Neurology, 265 (11), 2633-2645. doi: 10.1007/s00415-018-9043-0
2018
Journal Article
European Association of Nuclear Medicine and European Academy of Neurology recommendations for the use of brain 18 F-fluorodeoxyglucose positron emission tomography in neurodegenerative cognitive impairment and dementia: Delphi consensus
Nobili, F., Arbizu, J., Bouwman, F., Drzezga, A., Agosta, F., Nestor, P., Walker, Z., Boccardi, M. and for the EANM-EAN Task Force for the Prescription of FDG-PET for DementingNeurodegenerative Disorders (2018). European Association of Nuclear Medicine and European Academy of Neurology recommendations for the use of brain 18 F-fluorodeoxyglucose positron emission tomography in neurodegenerative cognitive impairment and dementia: Delphi consensus. European Journal of Neurology, 25 (10), 1201-1217. doi: 10.1111/ene.13728
2018
Journal Article
Quantitative susceptibility MRI to detect brain iron in amyotrophic lateral sclerosis
Acosta-Cabronero, Julio, Machts, Judith, Schreiber, Stefanie, Abdulla, Susanne, Kollewe, Katja, Petri, Susanne, Spotorno, Nicola, Kaufmann, Joern, Heinze, Hans-Jochen, Dengler, Reinhard, Vielhaber, Stefan and Nestor, Peter J. (2018). Quantitative susceptibility MRI to detect brain iron in amyotrophic lateral sclerosis. Radiology, 289 (1), 180112-203. doi: 10.1148/radiol.2018180112
2018
Journal Article
Differential involvement of forearm muscles in ALS does not relate to sonographic structural nerve alterations
Schreiber, Stefanie, Schreiber, Frank, Debska-Vielhaber, Grazyna, Garz, Cornelia, Hensiek, Nathalie, Machts, Judith, Abdulla, Susanne, Dengler, Reinhard, Petri, Susanne, Nestor, Peter J. and Vielhaber, Stefan (2018). Differential involvement of forearm muscles in ALS does not relate to sonographic structural nerve alterations. Clinical Neurophysiology, 129 (7), 1438-1443. doi: 10.1016/j.clinph.2018.04.610
2018
Journal Article
Assessing FDG-PET diagnostic accuracy studies to develop recommendations for clinical use in dementia
Boccardi, Marina, Festari, Cristina, Altomare, Daniele, Gandolfo, Federica, Orini, Stefania, Nobili, Flavio, Frisoni, Giovanni B., EANM-EAN Task Force, Agosta, Federica, Arbizu, Javier, Bouwman, Femke, Drzezga, Alexander, Nestor, Peter and Walker, Zuzana (2018). Assessing FDG-PET diagnostic accuracy studies to develop recommendations for clinical use in dementia. European Journal of Nuclear Medicine and Molecular Imaging, 45 (9), 1470-1486. doi: 10.1007/s00259-018-4024-1
2018
Journal Article
Clinical utility of FDG PET in Parkinson's disease and atypical parkinsonism associated with dementia
Walker, Zuzana, Gandolfo, Federica, Orini, Stefania, Garibotto, Valentina, Agosta, Federica, Arbizu, Javier, Bouwman, Femke, Drzezga, Alexander, Nestor, Peter, Boccardi, Marina, Altomare, Daniele, Festari, Cristina, Nobili, Flavio and EANM-EAN Task Force for the recommendation of FDG PET for Dementing Neurodegenerative Disorders (2018). Clinical utility of FDG PET in Parkinson's disease and atypical parkinsonism associated with dementia. European journal of nuclear medicine and molecular imaging, 45 (9), 1534-1545. doi: 10.1007/s00259-018-4031-2
2018
Journal Article
Diagnostic utility of 18F-Fluorodeoxyglucose positron emission tomography (FDG-PET) in asymptomatic subjects at increased risk for Alzheimer’s disease
Drzezga, Alexander, Altomare, Daniele, Festari, Cristina, Arbizu, Javier, Orini, Stefania, Herholz, Karl, Nestor, Peter, Agosta, Federica, Bouwman, Femke, Nobili, Flavio, Walker, Zuzana, Frisoni, Giovanni Battista, Boccardi, Marina and EANM-EAN Task Force for the Prescription of FDG-PET for Dementing Neurodegenerative Disorders (2018). Diagnostic utility of 18F-Fluorodeoxyglucose positron emission tomography (FDG-PET) in asymptomatic subjects at increased risk for Alzheimer’s disease. European Journal of Nuclear Medicine and Molecular Imaging, 45 (9), 1-10. doi: 10.1007/s00259-018-4032-1
2018
Journal Article
Diagnostic utility of FDG-PET in the differential diagnosis between different forms of primary progressive aphasia
Bouwman, Femke, Orini, Stefania, Gandolfo, Federica, Altomare, Daniele, Festari, Cristina, Agosta, Federica, Arbizu, Javier, Drzezga, Alexander, Nestor, Peter, Nobili, Flavio, Walker, Zuzana, Morbelli, Silvia, Boccardi, Marina and EANM-EAN Task Force for the Prescription of FDG-PET for Dementing Neurodegenerative Disorders (2018). Diagnostic utility of FDG-PET in the differential diagnosis between different forms of primary progressive aphasia. European Journal of Nuclear Medicine and Molecular Imaging, 45 (9), 1526-1533. doi: 10.1007/s00259-018-4034-z
2018
Journal Article
Clinical utility of FDG-PET for the differential diagnosis among the main forms of dementia
Nestor, Peter J., Altomare, Daniele, Festari, Cristina, Drzezga, Alexander, Rivolta, Jasmine, Walker, Zuzana, Bouwman, Femke, Orini, Stefania, Law, Ian, Agosta, Federica, Arbizu, Javier, Boccardi, Marina, Nobili, Flavio, Frisoni, Giovanni Battista and EANM-EAN Task Force for the Prescription of FDG-PET for Dementing Neurodegenerative Disorders (2018). Clinical utility of FDG-PET for the differential diagnosis among the main forms of dementia. European Journal of Nuclear Medicine and Molecular Imaging, 45 (9), 1509-1525. doi: 10.1007/s00259-018-4035-y
2018
Journal Article
Automated assessment of FDG-PET for differential diagnosis in patients with neurodegenerative disorders
Nobili, Flavio, Festari, Cristina, Altomare, Daniele, Agosta, Federica, Orini, Stefania, Van Laere, Koen, Arbizu, Javier, Bouwman, Femke, Drzezga, Alexander, Nestor, Peter, Walker, Zuzana, Boccardi, Marina and EANM-EAN Task Force for the Prescription of FDG-PET for Dementing Neurodegenerative Disorders (2018). Automated assessment of FDG-PET for differential diagnosis in patients with neurodegenerative disorders. European Journal of Nuclear Medicine and Molecular Imaging, 45 (9), 1557-1566. doi: 10.1007/s00259-018-4030-3
2018
Journal Article
Clinical utility of FDG-PET in amyotrophic lateral sclerosis and Huntington's disease
Agosta, Federica, Altomare, Daniele, Festari, Cristina, Orini, Stefania, Gandolfo, Federica, Boccardi, Marina, Arbizu, Javier, Bouwman, Femke, Drzezga, Alexander, Nestor, Peter, Nobili, Flavio, Walker, Zuzana, Pagani, Marco and EANM-EAN Task Force for the Prescription of FDG-PET for Dementing Neurodegenerative Disorders (2018). Clinical utility of FDG-PET in amyotrophic lateral sclerosis and Huntington's disease. European Journal of Nuclear Medicine and Molecular Imaging, 45 (9), 1546-1556. doi: 10.1007/s00259-018-4033-0
2018
Journal Article
Clinical utility of FDG-PET for the clinical diagnosis in MCI
Arbizu, Javier, Festari, Cristina, Altomare, Daniele, Walker, Zuzana, Bouwman, Femke, Rivolta, Jasmine, Orini, Stefania, Barthel, Henryk, Agosta, Federica, Drzezga, Alexander, Nestor, Peter, Boccardi, Marina, Frisoni, Giovanni Battista, Nobili, Flavio and EANM-EAN Task Force for the Prescription of FDG-PET for Dementing Neurodegenerative Disorders (2018). Clinical utility of FDG-PET for the clinical diagnosis in MCI. European Journal of Nuclear Medicine and Molecular Imaging, 45 (9), 1-12. doi: 10.1007/s00259-018-4039-7
2018
Journal Article
Prefrontal cortical thickness in motor neuron disease
Machts, Judith, Cardenas-Blanco, Arturo, Acosta-Cabronero, Julio, Kaufmann, Joern, Loewe, Kristian, Kasper, Elisabeth, Schuster, Christina, Prudlo, Johannes, Vielhaber, Stefan and Nestor, Peter J. (2018). Prefrontal cortical thickness in motor neuron disease. NeuroImage: Clinical, 18, 648-655. doi: 10.1016/j.nicl.2018.03.002
2018
Journal Article
Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease
Franzmeier, Nicolai, Düzel, Emrah, Jessen, Frank, Buerger, Katharina, Levin, Johannes, Duering, Marco, Dichgans, Martin, Haass, Christian, Suárez-Calvet, Marc, Fagan, Anne M, Paumier, Katrina, Benzinger, Tammie, Masters, Colin L, Morris, John C, Perneczky, Robert, Janowitz, Daniel, Catak, Cihan, Wolfsgruber, Steffen, Wagner, Michael, Teipel, Stefan, Kilimann, Ingo, Ramirez, Alfredo, Rossor, Martin, Jucker, Mathias, Chhatwal, Jasmeer, Spottke, Annika, Boecker, Henning, Brosseron, Frederic, Falkai, Peter ... Ewers, Michael (2018). Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease. Brain : A Journal of Neurology, 141 (4), 1186-1200. doi: 10.1093/brain/awy008
Supervision
Availability
- Professor Peter Nestor is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
The evolution of cognitive deficits in Lewy body disorders and related degenerative diseases.
Principal Advisor
Other advisors: Associate Professor John O'Sullivan
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Doctor Philosophy
Clinical utility of autobiographical memory in dementia diagnoses
Principal Advisor
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Doctor Philosophy
The `What¿ and `Where¿ of Visual Processing in Neurodegeneration: The essential yet overlooked component of diagnostic testing in dementia
Principal Advisor
Other advisors: Professor Jason Mattingley
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Doctor Philosophy
Diagnostic specificity in frontotemporal dementia
Principal Advisor
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Doctor Philosophy
Cognitive switching in ageing and preclinical neurodegenerative disorders
Associate Advisor
Other advisors: Professor Gail Robinson
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Doctor Philosophy
Attentional Switching in Healthy Ageing and Neurodegenerative Disorders
Associate Advisor
Other advisors: Professor Gail Robinson
Completed supervision
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2024
Doctor Philosophy
The `What' and `Where' of Visual Processing in Neurodegeneration: The essential yet overlooked component of diagnostic testing in dementia
Principal Advisor
Other advisors: Professor Jason Mattingley
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2021
Doctor Philosophy
Neuroimaging of Traumatic Brain Injury and Dementia: Bridging the link
Associate Advisor
Other advisors: Associate Professor Fatima Nasrallah
Media
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