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Professor Peter Nestor
Professor

Peter Nestor

Email: 

Overview

Background

Prof Nestor joined the Queensland Brain Institute in October/2017 and has a conjoint appointment as a cognitive neurologist at Mater Misericordiae Ltd (Mater Hospital).

His particular interests include understanding the earliest stages of Alzheimer's disease (i.e. before dementia is established); atypical forms of dementia with a particular focus on primary progressive aphasia and dementias related to Parkinson's and Lewy body diseases; and improving differential diagnosis between the major categories of neurodegenerative diseases.

He works on development of neuropsychological tests of cognition, both to accurately track change over time and improve diagnostic accuracy between the major diseases causing dementia. He also uses multi-modal imaging (magnetic resonance imaging [MRI] and positron emission tomography [PET]) to understand the sequence of events occurring in degenerative brain diseases (particularly Alzheimer's disease, frontotemporal dementia, Parkinson's disease, motor neuron disease [ALS], progressive supranuclear palsy [PSP] and corticobasal degeneration [CBD]) and identify novel biomarkers. A major focus of his is on developing novel approaches to MR imaging for single subject pathological diagnoses that can be exported into the everyday clinical setting; recent examples include diffusion tensor imaging to identify PSP and CBD (Sajjadi et al, 2013) and quantitative susceptibility mapping in Parkinson's disease (Acosta-Cabornero et al, 2013).

Availability

Professor Peter Nestor is:
Available for supervision

Qualifications

  • Bachelor of Medicine and Surgery and Medical Science, University of Melbourne
  • Doctor of Philosophy, University of Cambridge

Research interests

  • Cognitive neurology

  • frontotemporal lobar degeneration

  • progressive aphasia

  • Alzheimer's disease

  • Neurodegenerative diseases

Works

Search Professor Peter Nestor’s works on UQ eSpace

176 works between 1996 and 2025

21 - 40 of 176 works

2022

Conference Publication

Hallucinations and misperceptions in neurodegenerative diseases

McCann, Emily and Nestor, Peter (2022). Hallucinations and misperceptions in neurodegenerative diseases. UQ Neuroscience Symposium, Brisbane, QLD Australia, 26 - 27 September 2022.

Hallucinations and misperceptions in neurodegenerative diseases

2022

Journal Article

Support vector machine learning and diffusion-derived structural networks predict amyloid quantity and cognition in adults with Down's syndrome

Brown, Stephanie S.G., Mak, Elijah, Clare, Isabel, Grigorova, Monika, Beresford-Webb, Jessica, Walpert, Madeline, Jones, Elizabeth, Hong, Young T., Fryer, Tim D., Coles, Jonathan P., Aigbirhio, Franklin I., Tudorascu, Dana, Cohen, Annie, Christian, Bradley T., Handen, Benjamin L., Klunk, William E., Menon, David K., Nestor, Peter J., Holland, Anthony J. and Zaman, Shahid H. (2022). Support vector machine learning and diffusion-derived structural networks predict amyloid quantity and cognition in adults with Down's syndrome. Neurobiology of Aging, 115, 112-121. doi: 10.1016/j.neurobiolaging.2022.02.013

Support vector machine learning and diffusion-derived structural networks predict amyloid quantity and cognition in adults with Down's syndrome

2022

Conference Publication

Fragile X-Associated Neuropsychiatric Conditions (FXANC)

Flavell, J., Franklin, C. and Nestor, P. (2022). Fragile X-Associated Neuropsychiatric Conditions (FXANC). RANZCP Congress 2022, Sydney, NSW Australia, 15-19 May 2022. London, United Kingdom: SAGE Publications. doi: 10.1177/00048674221088686

Fragile X-Associated Neuropsychiatric Conditions (FXANC)

2021

Journal Article

Metabolic derangements are associated with impaired glucose delivery following traumatic brain injury

Hermanides, Jeroen, Hong, Young T., Trivedi, Monica, Outtrim, Joanne, Aigbirhio, Franklin, Nestor, Peter J., Guilfoyle, Matthew, Winzeck, Stefan, Newcombe, Virginia F. J., Das, Tilak, Correia, Marta M., Carpenter, Keri L. H., Hutchinson, Peter J. A., Gupta, Arun K., Fryer, Tim D., Pickard, John D., Menon, David K. and Coles, Jonathan P. (2021). Metabolic derangements are associated with impaired glucose delivery following traumatic brain injury. Brain, 144 (11), 3492-3504. doi: 10.1093/brain/awab255

Metabolic derangements are associated with impaired glucose delivery following traumatic brain injury

2021

Journal Article

What Lies Behind the Construct of Primary Progressive Aphasia?

Preiss, Daniel, Billette, Ornella and Nestor, Peter J. (2021). What Lies Behind the Construct of Primary Progressive Aphasia?. Sprache-Stimme-Gehor, 45 (04), 173-178. doi: 10.1055/a-1557-8330

What Lies Behind the Construct of Primary Progressive Aphasia?

2021

Journal Article

What’s “up”?: impaired spatial preposition processing in posterior cortical atrophy

Shebani, Zubaida, Nestor, Peter J. and Pulvermüller, Friedemann (2021). What’s “up”?: impaired spatial preposition processing in posterior cortical atrophy. Frontiers in Human Neuroscience, 15 731104, 731104. doi: 10.3389/fnhum.2021.731104

What’s “up”?: impaired spatial preposition processing in posterior cortical atrophy

2021

Conference Publication

Visuoperception in Neurodegenerative diseases

McCann, Emily and Nestor, Peter (2021). Visuoperception in Neurodegenerative diseases. Queensland Brain Institute: Genomics, Clinical Research Theme Meeting, Brisbane, QLD Australia, 26 November 2021.

Visuoperception in Neurodegenerative diseases

2021

Conference Publication

Development of new tests for Dementia diagnoses

McCann, Emily and Nestor, Peter (2021). Development of new tests for Dementia diagnoses. Clem Jones Centre for Ageing and Dementia Research (CJCADR) Retreat, Brisbane, QLD Australia, 26 November 2021.

Development of new tests for Dementia diagnoses

2021

Journal Article

Traumatic brain injury fast-forwards Alzheimer’s pathology: evidence from amyloid positron emission tomorgraphy imaging

Mohamed, Abdalla Z., Nestor, Peter J., Cumming, Paul, Nasrallah, Fatima A. and for the Alzheimer’s Disease Neuroimaging Initiative (2021). Traumatic brain injury fast-forwards Alzheimer’s pathology: evidence from amyloid positron emission tomorgraphy imaging. Journal of Neurology, 269 (2), 873-884. doi: 10.1007/s00415-021-10669-5

Traumatic brain injury fast-forwards Alzheimer’s pathology: evidence from amyloid positron emission tomorgraphy imaging

2021

Journal Article

A systematic review of apathy and depression in progressive supranuclear palsy

Flavell, Joshua and Nestor, Peter J. (2021). A systematic review of apathy and depression in progressive supranuclear palsy. Journal of Geriatric Psychiatry and Neurology, 35 (3), 891988721993545-292. doi: 10.1177/0891988721993545

A systematic review of apathy and depression in progressive supranuclear palsy

2020

Conference Publication

Hippocampal volumetric variability is associated with memory in subjective cognitive decline : Neuroimaging / Optimal neuroimaging measures for early detection

Ziegler, Gabriel, Heinzinger, Nils, Metzger, Coraline D., Yakupov, Renat, Bittner, Daniel, Glanz, Wenzel, Spottke, Annika, Brosseron, Frederic, Bürger, Katharina, Fließbach, Klaus, Heneka, Michael T., Laske, Christoph, Nestor, Peter J., Peters, Oliver, Priller, Josef, Ramirez, Alfredo, Schneider, Anja, Speck, Oliver, Teipel, Stefan J., Wiltfang, Jens, Wagner, Michael, Düzel, Emrah and Jessen, Frank (2020). Hippocampal volumetric variability is associated with memory in subjective cognitive decline : Neuroimaging / Optimal neuroimaging measures for early detection. Alzheimer's Association International Conference (AAIC 2020), Online, 27-31 July 2020. Hoboken, NJ, United States: Wiley. doi: 10.1002/alz.043527

Hippocampal volumetric variability is associated with memory in subjective cognitive decline : Neuroimaging / Optimal neuroimaging measures for early detection

2020

Journal Article

Measuring cerebral perfusion with [11C]-PiB R1 in Down syndrome: associations with amyloid burden and longitudinal cognitive decline

Mak, Elijah, Grigorova, Monika, Beresford-Webb, Jessica, Malpetti, Maura, Walpert, Madeline, Brown, Stephanie, Jones, Elizabeth, Clare, Isabel, Hong, Young T., Fryer, Tim D., Coles, Jonathan P., Aigbirhio, Franklin I., Menon, David K., Nestor, Peter J., Holland, Anthony J. and Zaman, Shahid H (2020). Measuring cerebral perfusion with [11C]-PiB R1 in Down syndrome: associations with amyloid burden and longitudinal cognitive decline. Brain Communications, 3 (1) fcaa198, fcaa198. doi: 10.1093/braincomms/fcaa198

Measuring cerebral perfusion with [11C]-PiB R1 in Down syndrome: associations with amyloid burden and longitudinal cognitive decline

2020

Journal Article

The upper cervical spinal cord in ALS assessed by cross-sectional and longitudinal 3T MRI

Wimmer, Thomas, Schreiber, Frank, Hensiek, Nathalie, Garz, Cornelia, Kaufmann, Jörn, Machts, Judith, Vogt, Susanne, Prudlo, Johannes, Dengler, Reinhard, Petri, Susanne, Heinze, Hans-Jochen, Nestor, Peter J., Vielhaber, Stefan and Schreiber, Stefanie (2020). The upper cervical spinal cord in ALS assessed by cross-sectional and longitudinal 3T MRI. Scientific Reports, 10 (1) 1783, 1783. doi: 10.1038/s41598-020-58687-z

The upper cervical spinal cord in ALS assessed by cross-sectional and longitudinal 3T MRI

2020

Journal Article

7T MR neurography-ultrasound fusion for peripheral nerve imaging

Schreiber, Stefanie, Schreiber, Frank, Peter, Alica, Isler, Eser, Doerner, Marc, Heinze, Hans-Jochen, Petri, Suanne, Tempelmann, Claus, Nestor, Peter J., Grimm, Alexander and Vielhaber, Stefan (2020). 7T MR neurography-ultrasound fusion for peripheral nerve imaging. Muscle and Nerve, 61 (4) mus.26800, 1-6. doi: 10.1002/mus.26800

7T MR neurography-ultrasound fusion for peripheral nerve imaging

2020

Journal Article

A multi-contrast MRI approach to thalamus segmentation

Corona, Veronica, Lellmann, Jan, Nestor, Peter, Schoenlieb, Carola-Bibiane and Acosta-Cabronero, Julio (2020). A multi-contrast MRI approach to thalamus segmentation. Human Brain Mapping, 41 (8) hbm.24933, 2104-2120. doi: 10.1002/hbm.24933

A multi-contrast MRI approach to thalamus segmentation

2020

Journal Article

Prominent white matter involvement in multiple system atrophy of cerebellar type

Faber, Jennifer, Giordano, Ilaria, Jiang, Xueyan, Kindler, Christine, Spottke, Annika, Acosta-Cabronero, Julio, Nestor, Peter J., Machts, Judith, Düzel, Emrah, Vielhaber, Stefan, Speck, Oliver, Dudesek, Ales, Kamm, Christoph, Scheef, Lukas and Klockgether, Thomas (2020). Prominent white matter involvement in multiple system atrophy of cerebellar type. Movement Disorders, 35 (5) mds.27987, 816-824. doi: 10.1002/mds.27987

Prominent white matter involvement in multiple system atrophy of cerebellar type

2020

Journal Article

Sonographic and 3T-MRI-based evaluation of the tongue in ALS

Hensiek, Nathalie, Schreiber, Frank, Wimmer, Thomas, Kaufmann, Jörn, Machts, Judith, Fahlbusch, Laura, Garz, Cornelia, Vogt, Susanne, Prudlo, Johannes, Dengler, Reinhard, Petri, Susanne, Nestor, Peter J., Vielhaber, Stefan and Schreiber, Stefanie (2020). Sonographic and 3T-MRI-based evaluation of the tongue in ALS. NeuroImage: Clinical, 26 102233, 102233. doi: 10.1016/j.nicl.2020.102233

Sonographic and 3T-MRI-based evaluation of the tongue in ALS

2019

Journal Article

Longitudinal trajectories of amyloid deposition, cortical thickness, and tau in Down syndrome: A deep-phenotyping case report

Mak, Elijah, Bickerton, Anastasia, Padilla, Concepcion, Walpert, Madeleine J., Annus, Tiina, Wilson, Liam R., Hong, Young T., Fryer, Tim D., Coles, Jonathan P., Aigbirhio, Franklin I., Christian, Bradley T., Handen, Benjamin L., Klunk, William E., Menon, David K., Nestor, Peter J., Zaman, Shahid H. and Holland, Anthony J. (2019). Longitudinal trajectories of amyloid deposition, cortical thickness, and tau in Down syndrome: A deep-phenotyping case report. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 11 (C), 654-658. doi: 10.1016/j.dadm.2019.04.006

Longitudinal trajectories of amyloid deposition, cortical thickness, and tau in Down syndrome: A deep-phenotyping case report

2019

Journal Article

Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders: Proposal for a Neuroimaging Biomarker Utility System

van Eimeren, Thilo, Antonini, Angelo, Berg, Daniela, Bohnen, Nico, Ceravolo, Roberto, Drzezga, Alexander, Höglinger, Günter U., Higuchi, Makoto, Lehericy, Stephane, Lewis, Simon, Monchi, Oury, Nestor, Peter, Ondrus, Matej, Pavese, Nicola, Peralta, María Cecilia, Piccini, Paola, Pineda-Pardo, José Ángel, Rektorová, Irena, Rodríguez-Oroz, María, Rominger, Axel, Seppi, Klaus, Stoessl, A. Jon, Tessitore, Alessandro, Thobois, Stephane, Kaasinen, Valtteri, Wenning, Gregor, Siebner, Hartwig R., Strafella, Antonio P. and Rowe, James B. (2019). Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders: Proposal for a Neuroimaging Biomarker Utility System. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 11 (C), 301-309. doi: 10.1016/j.dadm.2019.01.011

Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders: Proposal for a Neuroimaging Biomarker Utility System

2019

Journal Article

Diffusion tensor MRI to distinguish progressive supranuclear palsy from α-synucleinopathies

Spotorno, Nicola, Hall, Sara, Irwin, David J., Rumetshofer, Theodor, Acosta-Cabronero, Julio, Deik, Andres F., Spindler, Meredith A., Lee, Edward B., Trojanowski, John Q., van Westen, Danielle, Nilsson, Markus, Grossman, Murray, Nestor, Peter J., McMillan, Corey T. and Hansson, Oskar (2019). Diffusion tensor MRI to distinguish progressive supranuclear palsy from α-synucleinopathies. Radiology, 293 (3), 190406-653. doi: 10.1148/radiol.2019190406

Diffusion tensor MRI to distinguish progressive supranuclear palsy from α-synucleinopathies

Funding

Current funding

  • 2024 - 2029
    Centre of Research Excellence in Mechanisms In NeuroDegeneration - Alzheimer's Disease (MIND-AD CRE)
    NHMRC Centres of Research Excellence
    Open grant
  • 2024 - 2026
    Disambiguating Parkinson's disease from disorders with mimicking symptoms using ultra-high-field (7 Tesla) multi-modal MRI
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2023 - 2024
    Use of advanced magnetic resonance imaging (MRI) technology to improve understanding and diagnosis of the major neurodegenerative diseases
    Metro North Hospital and Health Service
    Open grant

Supervision

Availability

Professor Peter Nestor is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    The evolution of cognitive deficits in Lewy body disorders and related degenerative diseases.

    Principal Advisor

    Other advisors: Associate Professor John O'Sullivan

  • Doctor Philosophy

    Clinical utility of autobiographical memory in dementia diagnoses

    Principal Advisor

  • Doctor Philosophy

    The `What¿ and `Where¿ of Visual Processing in Neurodegeneration: The essential yet overlooked component of diagnostic testing in dementia

    Principal Advisor

    Other advisors: Professor Jason Mattingley

  • Doctor Philosophy

    Diagnostic specificity in frontotemporal dementia

    Principal Advisor

  • Doctor Philosophy

    Attentional Switching in Healthy Ageing and Neurodegenerative Disorders

    Associate Advisor

    Other advisors: Professor Gail Robinson

  • Doctor Philosophy

    Cognitive switching in ageing and preclinical neurodegenerative disorders

    Associate Advisor

    Other advisors: Professor Gail Robinson

Completed supervision

Media

Enquiries

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