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Professor Peter Nestor
Professor

Peter Nestor

Email: 

Overview

Background

Prof Nestor joined the Queensland Brain Institute in October/2017 and has a conjoint appointment as a cognitive neurologist at Mater Misericordiae Ltd (Mater Hospital).

His particular interests include understanding the earliest stages of Alzheimer's disease (i.e. before dementia is established); atypical forms of dementia with a particular focus on primary progressive aphasia and dementias related to Parkinson's and Lewy body diseases; and improving differential diagnosis between the major categories of neurodegenerative diseases.

He works on development of neuropsychological tests of cognition, both to accurately track change over time and improve diagnostic accuracy between the major diseases causing dementia. He also uses multi-modal imaging (magnetic resonance imaging [MRI] and positron emission tomography [PET]) to understand the sequence of events occurring in degenerative brain diseases (particularly Alzheimer's disease, frontotemporal dementia, Parkinson's disease, motor neuron disease [ALS], progressive supranuclear palsy [PSP] and corticobasal degeneration [CBD]) and identify novel biomarkers. A major focus of his is on developing novel approaches to MR imaging for single subject pathological diagnoses that can be exported into the everyday clinical setting; recent examples include diffusion tensor imaging to identify PSP and CBD (Sajjadi et al, 2013) and quantitative susceptibility mapping in Parkinson's disease (Acosta-Cabornero et al, 2013).

Availability

Professor Peter Nestor is:
Available for supervision

Qualifications

  • Bachelor of Medicine and Surgery and Medical Science, University of Melbourne
  • Doctor of Philosophy, University of Cambridge

Research interests

  • Cognitive neurology

  • frontotemporal lobar degeneration

  • progressive aphasia

  • Alzheimer's disease

  • Neurodegenerative diseases

Works

Search Professor Peter Nestor’s works on UQ eSpace

163 works between 1996 and 2024

21 - 40 of 163 works

2020

Journal Article

7T MR neurography-ultrasound fusion for peripheral nerve imaging

Schreiber, Stefanie, Schreiber, Frank, Peter, Alica, Isler, Eser, Doerner, Marc, Heinze, Hans-Jochen, Petri, Suanne, Tempelmann, Claus, Nestor, Peter J., Grimm, Alexander and Vielhaber, Stefan (2020). 7T MR neurography-ultrasound fusion for peripheral nerve imaging. Muscle and Nerve, 61 (4) mus.26800, 1-6. doi: 10.1002/mus.26800

7T MR neurography-ultrasound fusion for peripheral nerve imaging

2020

Journal Article

A multi-contrast MRI approach to thalamus segmentation

Corona, Veronica, Lellmann, Jan, Nestor, Peter, Schoenlieb, Carola-Bibiane and Acosta-Cabronero, Julio (2020). A multi-contrast MRI approach to thalamus segmentation. Human Brain Mapping, 41 (8) hbm.24933, 2104-2120. doi: 10.1002/hbm.24933

A multi-contrast MRI approach to thalamus segmentation

2020

Journal Article

Prominent white matter involvement in multiple system atrophy of cerebellar type

Faber, Jennifer, Giordano, Ilaria, Jiang, Xueyan, Kindler, Christine, Spottke, Annika, Acosta-Cabronero, Julio, Nestor, Peter J., Machts, Judith, Düzel, Emrah, Vielhaber, Stefan, Speck, Oliver, Dudesek, Ales, Kamm, Christoph, Scheef, Lukas and Klockgether, Thomas (2020). Prominent white matter involvement in multiple system atrophy of cerebellar type. Movement Disorders, 35 (5) mds.27987, 816-824. doi: 10.1002/mds.27987

Prominent white matter involvement in multiple system atrophy of cerebellar type

2020

Journal Article

Sonographic and 3T-MRI-based evaluation of the tongue in ALS

Hensiek, Nathalie, Schreiber, Frank, Wimmer, Thomas, Kaufmann, Jörn, Machts, Judith, Fahlbusch, Laura, Garz, Cornelia, Vogt, Susanne, Prudlo, Johannes, Dengler, Reinhard, Petri, Susanne, Nestor, Peter J., Vielhaber, Stefan and Schreiber, Stefanie (2020). Sonographic and 3T-MRI-based evaluation of the tongue in ALS. NeuroImage: Clinical, 26 102233, 102233. doi: 10.1016/j.nicl.2020.102233

Sonographic and 3T-MRI-based evaluation of the tongue in ALS

2019

Journal Article

Longitudinal trajectories of amyloid deposition, cortical thickness, and tau in Down syndrome: A deep-phenotyping case report

Mak, Elijah, Bickerton, Anastasia, Padilla, Concepcion, Walpert, Madeleine J., Annus, Tiina, Wilson, Liam R., Hong, Young T., Fryer, Tim D., Coles, Jonathan P., Aigbirhio, Franklin I., Christian, Bradley T., Handen, Benjamin L., Klunk, William E., Menon, David K., Nestor, Peter J., Zaman, Shahid H. and Holland, Anthony J. (2019). Longitudinal trajectories of amyloid deposition, cortical thickness, and tau in Down syndrome: A deep-phenotyping case report. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 11 (C), 654-658. doi: 10.1016/j.dadm.2019.04.006

Longitudinal trajectories of amyloid deposition, cortical thickness, and tau in Down syndrome: A deep-phenotyping case report

2019

Journal Article

Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders: Proposal for a Neuroimaging Biomarker Utility System

van Eimeren, Thilo, Antonini, Angelo, Berg, Daniela, Bohnen, Nico, Ceravolo, Roberto, Drzezga, Alexander, Höglinger, Günter U., Higuchi, Makoto, Lehericy, Stephane, Lewis, Simon, Monchi, Oury, Nestor, Peter, Ondrus, Matej, Pavese, Nicola, Peralta, María Cecilia, Piccini, Paola, Pineda-Pardo, José Ángel, Rektorová, Irena, Rodríguez-Oroz, María, Rominger, Axel, Seppi, Klaus, Stoessl, A. Jon, Tessitore, Alessandro, Thobois, Stephane, Kaasinen, Valtteri, Wenning, Gregor, Siebner, Hartwig R., Strafella, Antonio P. and Rowe, James B. (2019). Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders: Proposal for a Neuroimaging Biomarker Utility System. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 11 (C), 301-309. doi: 10.1016/j.dadm.2019.01.011

Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders: Proposal for a Neuroimaging Biomarker Utility System

2019

Journal Article

Diffusion tensor MRI to distinguish progressive supranuclear palsy from α-synucleinopathies

Spotorno, Nicola, Hall, Sara, Irwin, David J., Rumetshofer, Theodor, Acosta-Cabronero, Julio, Deik, Andres F., Spindler, Meredith A., Lee, Edward B., Trojanowski, John Q., van Westen, Danielle, Nilsson, Markus, Grossman, Murray, Nestor, Peter J., McMillan, Corey T. and Hansson, Oskar (2019). Diffusion tensor MRI to distinguish progressive supranuclear palsy from α-synucleinopathies. Radiology, 293 (3), 190406-653. doi: 10.1148/radiol.2019190406

Diffusion tensor MRI to distinguish progressive supranuclear palsy from α-synucleinopathies

2019

Journal Article

Differential effects of Down's syndrome and Alzheimer's neuropathology on default mode connectivity

Wilson, Liam R., Vatansever, Deniz, Annus, Tiina, Williams, Guy B., Hong, Young T., Fryer, Tim D., Nestor, Peter J., Holland, Anthony J. and Zaman, Shahid H. (2019). Differential effects of Down's syndrome and Alzheimer's neuropathology on default mode connectivity. Human Brain Mapping, 40 (15) hbm.24720, 4551-4563. doi: 10.1002/hbm.24720

Differential effects of Down's syndrome and Alzheimer's neuropathology on default mode connectivity

2019

Journal Article

The atrophy pattern in Alzheimer-related PPA is more widespread than that of the frontotemporal lobar degeneration associated variants

Preiß, Daniel, Billette, Ornella V., Schneider, Anja, Spotorno, Nicola and Nestor, Peter J. (2019). The atrophy pattern in Alzheimer-related PPA is more widespread than that of the frontotemporal lobar degeneration associated variants. NeuroImage: Clinical, 24 101994, 101994. doi: 10.1016/j.nicl.2019.101994

The atrophy pattern in Alzheimer-related PPA is more widespread than that of the frontotemporal lobar degeneration associated variants

2019

Journal Article

Delineating the topography of amyloid-associated cortical atrophy in Down syndrome

Mak, Elijah, Padilla, Concepcion, Annus, Tiina, Wilson, Liam R., Hong, Young T., Fryer, Tim D., Coles, Jonathan P., Aigbirhio, Franklin I., Menon, David K., Nestor, Peter J., Zaman, Shahid H. and Holland, Anthony J. (2019). Delineating the topography of amyloid-associated cortical atrophy in Down syndrome. Neurobiology of Aging, 80, 196-202. doi: 10.1016/j.neurobiolaging.2019.02.018

Delineating the topography of amyloid-associated cortical atrophy in Down syndrome

2019

Journal Article

Toward in vivo determination of peripheral nervous system immune activity in amyotrophic lateral sclerosis

Schreiber, Stefanie, Schreiber, Frank, Garz, Cornelia, Debska-Vielhaber, Grazyna, Assmann, Anne, Perosa, Valentina, Petri, Susanne, Dengler, Reinhard, Nestor, Peter and Vielhaber, Stefan (2019). Toward in vivo determination of peripheral nervous system immune activity in amyotrophic lateral sclerosis. Muscle and Nerve, 59 (5), 567-576. doi: 10.1002/mus.26444

Toward in vivo determination of peripheral nervous system immune activity in amyotrophic lateral sclerosis

2019

Journal Article

The BDNF Val66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer’s disease

Franzmeier, Nicolai, Ren, Jinyi, Damm, Alexander, Monté-Rubio, Gemma, Boada, Mercè, Ruiz, Agustín, Ramirez, Alfredo, Jessen, Frank, Düzel, Emrah, Rodríguez Gómez, Octavio, Benzinger, Tammie, Goate, Alison, Karch, Celeste M., Fagan, Anne M., McDade, Eric, Buerger, Katharina, Levin, Johannes, Duering, Marco, Dichgans, Martin, Suárez-Calvet, Marc, Haass, Christian, Gordon, Brian A., Lim, Yen Ying, Masters, Colin L., Janowitz, Daniel, Catak, Cihan, Wolfsgruber, Steffen, Wagner, Michael, Milz, Esther ... Ewers, Michael (2019). The BDNF Val66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer’s disease. Molecular Psychiatry, 26 (2), 614-628. doi: 10.1038/s41380-019-0404-6

The BDNF Val66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer’s disease

2019

Journal Article

The concept of regularization: resolving the problem of surface dyslexia in semantic variant primary progressive aphasia across different languages

Billette, Ornella V., Preib, Daniel and Nestor, Peter J. (2019). The concept of regularization: resolving the problem of surface dyslexia in semantic variant primary progressive aphasia across different languages. Neuropsychology, 34 (3), 298-307. doi: 10.1037/neu0000611

The concept of regularization: resolving the problem of surface dyslexia in semantic variant primary progressive aphasia across different languages

2018

Journal Article

Significance of CSF NfL and tau in ALS

Schreiber, Stefanie, Spotorno, Nicola, Schreiber, Frank, Acosta-Cabronero, Julio, Kaufmann, Jörn, Machts, Judith, Debska-Vielhaber, Grazyna, Garz, Cornelia, Bittner, Daniel, Hensiek, Nathalie, Dengler, Reinhard, Petri, Susanne, Nestor, Peter J. and Vielhaber, Stefan (2018). Significance of CSF NfL and tau in ALS. Journal of Neurology, 265 (11), 2633-2645. doi: 10.1007/s00415-018-9043-0

Significance of CSF NfL and tau in ALS

2018

Journal Article

European Association of Nuclear Medicine and European Academy of Neurology recommendations for the use of brain 18 F-fluorodeoxyglucose positron emission tomography in neurodegenerative cognitive impairment and dementia: Delphi consensus

Nobili, F., Arbizu, J., Bouwman, F., Drzezga, A., Agosta, F., Nestor, P., Walker, Z., Boccardi, M. and for the EANM-EAN Task Force for the Prescription of FDG-PET for DementingNeurodegenerative Disorders (2018). European Association of Nuclear Medicine and European Academy of Neurology recommendations for the use of brain 18 F-fluorodeoxyglucose positron emission tomography in neurodegenerative cognitive impairment and dementia: Delphi consensus. European Journal of Neurology, 25 (10), 1201-1217. doi: 10.1111/ene.13728

European Association of Nuclear Medicine and European Academy of Neurology recommendations for the use of brain 18 F-fluorodeoxyglucose positron emission tomography in neurodegenerative cognitive impairment and dementia: Delphi consensus

2018

Journal Article

Quantitative susceptibility MRI to detect brain iron in amyotrophic lateral sclerosis

Acosta-Cabronero, Julio, Machts, Judith, Schreiber, Stefanie, Abdulla, Susanne, Kollewe, Katja, Petri, Susanne, Spotorno, Nicola, Kaufmann, Joern, Heinze, Hans-Jochen, Dengler, Reinhard, Vielhaber, Stefan and Nestor, Peter J. (2018). Quantitative susceptibility MRI to detect brain iron in amyotrophic lateral sclerosis. Radiology, 289 (1), 180112-203. doi: 10.1148/radiol.2018180112

Quantitative susceptibility MRI to detect brain iron in amyotrophic lateral sclerosis

2018

Journal Article

Differential involvement of forearm muscles in ALS does not relate to sonographic structural nerve alterations

Schreiber, Stefanie, Schreiber, Frank, Debska-Vielhaber, Grazyna, Garz, Cornelia, Hensiek, Nathalie, Machts, Judith, Abdulla, Susanne, Dengler, Reinhard, Petri, Susanne, Nestor, Peter J. and Vielhaber, Stefan (2018). Differential involvement of forearm muscles in ALS does not relate to sonographic structural nerve alterations. Clinical Neurophysiology, 129 (7), 1438-1443. doi: 10.1016/j.clinph.2018.04.610

Differential involvement of forearm muscles in ALS does not relate to sonographic structural nerve alterations

2018

Journal Article

Assessing FDG-PET diagnostic accuracy studies to develop recommendations for clinical use in dementia

Boccardi, Marina, Festari, Cristina, Altomare, Daniele, Gandolfo, Federica, Orini, Stefania, Nobili, Flavio, Frisoni, Giovanni B., EANM-EAN Task Force, Agosta, Federica, Arbizu, Javier, Bouwman, Femke, Drzezga, Alexander, Nestor, Peter and Walker, Zuzana (2018). Assessing FDG-PET diagnostic accuracy studies to develop recommendations for clinical use in dementia. European Journal of Nuclear Medicine and Molecular Imaging, 45 (9), 1470-1486. doi: 10.1007/s00259-018-4024-1

Assessing FDG-PET diagnostic accuracy studies to develop recommendations for clinical use in dementia

2018

Journal Article

Clinical utility of FDG PET in Parkinson's disease and atypical parkinsonism associated with dementia

Walker, Zuzana, Gandolfo, Federica, Orini, Stefania, Garibotto, Valentina, Agosta, Federica, Arbizu, Javier, Bouwman, Femke, Drzezga, Alexander, Nestor, Peter, Boccardi, Marina, Altomare, Daniele, Festari, Cristina, Nobili, Flavio and EANM-EAN Task Force for the recommendation of FDG PET for Dementing Neurodegenerative Disorders (2018). Clinical utility of FDG PET in Parkinson's disease and atypical parkinsonism associated with dementia. European journal of nuclear medicine and molecular imaging, 45 (9), 1534-1545. doi: 10.1007/s00259-018-4031-2

Clinical utility of FDG PET in Parkinson's disease and atypical parkinsonism associated with dementia

2018

Journal Article

Diagnostic utility of 18F-Fluorodeoxyglucose positron emission tomography (FDG-PET) in asymptomatic subjects at increased risk for Alzheimer’s disease

Drzezga, Alexander, Altomare, Daniele, Festari, Cristina, Arbizu, Javier, Orini, Stefania, Herholz, Karl, Nestor, Peter, Agosta, Federica, Bouwman, Femke, Nobili, Flavio, Walker, Zuzana, Frisoni, Giovanni Battista, Boccardi, Marina and EANM-EAN Task Force for the Prescription of FDG-PET for Dementing Neurodegenerative Disorders (2018). Diagnostic utility of 18F-Fluorodeoxyglucose positron emission tomography (FDG-PET) in asymptomatic subjects at increased risk for Alzheimer’s disease. European Journal of Nuclear Medicine and Molecular Imaging, 45 (9), 1-10. doi: 10.1007/s00259-018-4032-1

Diagnostic utility of 18F-Fluorodeoxyglucose positron emission tomography (FDG-PET) in asymptomatic subjects at increased risk for Alzheimer’s disease

Funding

Current funding

  • 2024 - 2029
    Centre of Research Excellence in Mechanisms In NeuroDegeneration - Alzheimer's Disease (MIND-AD CRE)
    NHMRC Centres of Research Excellence
    Open grant
  • 2024 - 2026
    Disambiguating Parkinson's disease from disorders with mimicking symptoms using ultra-high-field (7 Tesla) multi-modal MRI
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2023 - 2024
    Use of advanced magnetic resonance imaging (MRI) technology to improve understanding and diagnosis of the major neurodegenerative diseases
    Metro North Hospital and Health Service
    Open grant

Supervision

Availability

Professor Peter Nestor is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    The evolution of cognitive deficits in Lewy body disorders and related degenerative diseases.

    Principal Advisor

    Other advisors: Associate Professor John O'Sullivan

  • Doctor Philosophy

    The `What¿ and `Where¿ of Visual Processing in Neurodegeneration: The essential yet overlooked component of diagnostic testing in dementia

    Principal Advisor

    Other advisors: Professor Jason Mattingley

  • Doctor Philosophy

    Diagnostic specificity in frontotemporal dementia

    Principal Advisor

  • Doctor Philosophy

    Cognitive switching in ageing and preclinical neurodegenerative disorders

    Associate Advisor

    Other advisors: Professor Gail Robinson

Completed supervision

Media

Enquiries

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