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Professor Peter Nestor
Professor

Peter Nestor

Email: 

Overview

Background

Prof Nestor joined the Queensland Brain Institute in October/2017 and has a conjoint appointment as a cognitive neurologist at Mater Misericordiae Ltd (Mater Hospital).

His particular interests include understanding the earliest stages of Alzheimer's disease (i.e. before dementia is established); atypical forms of dementia with a particular focus on primary progressive aphasia and dementias related to Parkinson's and Lewy body diseases; and improving differential diagnosis between the major categories of neurodegenerative diseases.

He works on development of neuropsychological tests of cognition, both to accurately track change over time and improve diagnostic accuracy between the major diseases causing dementia. He also uses multi-modal imaging (magnetic resonance imaging [MRI] and positron emission tomography [PET]) to understand the sequence of events occurring in degenerative brain diseases (particularly Alzheimer's disease, frontotemporal dementia, Parkinson's disease, motor neuron disease [ALS], progressive supranuclear palsy [PSP] and corticobasal degeneration [CBD]) and identify novel biomarkers. A major focus of his is on developing novel approaches to MR imaging for single subject pathological diagnoses that can be exported into the everyday clinical setting; recent examples include diffusion tensor imaging to identify PSP and CBD (Sajjadi et al, 2013) and quantitative susceptibility mapping in Parkinson's disease (Acosta-Cabornero et al, 2013).

Availability

Professor Peter Nestor is:
Available for supervision

Qualifications

  • Bachelor of Medicine and Surgery and Medical Science, University of Melbourne
  • Doctor of Philosophy, University of Cambridge

Research interests

  • Cognitive neurology

  • frontotemporal lobar degeneration

  • progressive aphasia

  • Alzheimer's disease

  • Neurodegenerative diseases

Works

Search Professor Peter Nestor’s works on UQ eSpace

163 works between 1996 and 2024

61 - 80 of 163 works

2017

Journal Article

Can MRI visual assessment differentiate the variants of primary-progressive aphasia?

Sajjadi, S. A., Sheikh-Bahaei, N., Cross, J., Gillard, J. H., Scoffings, D. and Nestor, P. J. (2017). Can MRI visual assessment differentiate the variants of primary-progressive aphasia?. American Journal of Neuroradiology, 38 (5), 954-960. doi: 10.3174/ajnr.A5126

Can MRI visual assessment differentiate the variants of primary-progressive aphasia?

2017

Journal Article

The Down syndrome brain in the presence and absence of fibrillar β-amyloidosis

Annus, Tiina, Wilson, Liam R., Acosta-Cabronero, Julio, Cardenas-Blanco, Arturo, Hong, Young T., Fryer, Tim D., Coles, Jonathan P., Menon, David K., Zaman, Shahid H., Holland, Anthony J. and Nestor, Peter J. (2017). The Down syndrome brain in the presence and absence of fibrillar β-amyloidosis. Neurobiology of Aging, 53, 11-19. doi: 10.1016/j.neurobiolaging.2017.01.009

The Down syndrome brain in the presence and absence of fibrillar β-amyloidosis

2017

Journal Article

Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis

Smith, Bradley N., Topp, Simon D., Fallini, Claudia, Shibata, Hideki, Chen, Han-Jou, Troakes, Claire, King, Andrew, Ticozzi, Nicola, Kenna, Kevin P., Soragia-Gkazi, Athina, Miller, Jack W., Sato, Akane, Dias, Diana Marques, Jeon, Maryangel, Vance, Caroline, Wong, Chun Hao, de Majo, Martina, Kattuah, Wejdan, Mitchell, Jacqueline C., Scotter, Emma L., Parkin, Nicholas W., Sapp, Peter C., Nolan, Matthew, Nestor, Peter J., Simpson, Michael, Weale, Michael, Lek, Monkel, Baas, Frank, de Jong, J. M. Vianney ... Shaw, Christopher E. (2017). Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis. Science Translational Medicine, 9 (388) aad9157, eaad9157. doi: 10.1126/scitranslmed.aad9157

Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis

2017

Journal Article

The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: Consensus document of the Joint Program for Neurodegenerative Diseases Working Group

Costa, Alberto, Bak, Thomas, Caffarra, Paolo, Caltagirone, Carlo, Ceccaldi, Mathieu, Collette, Fabienne, Crutch, Sebastian, Della Sala, Sergio, Demonet, Jean Francois, Dubois, Bruno, Duzel, Emrah, Nestor, Peter, Papageorgiou, Sokratis G., Salmon, Eric, Sikkes, Sietske, Tiraboschi, Pietro, van der Flier, Wiesje M., Visser, Pieter Jelle and Cappa, Stefano F. (2017). The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: Consensus document of the Joint Program for Neurodegenerative Diseases Working Group. Alzheimers Research & Therapy, 9 (1) 27. doi: 10.1186/s13195-017-0254-x

The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: Consensus document of the Joint Program for Neurodegenerative Diseases Working Group

2017

Journal Article

The whole-brain pattern of magnetic susceptibility perturbations in Parkinson's disease

Acosta-Cabronero, Julio, Cardenas-Blanco, Arturo, Betts, Matthew J., Butryn, Michaela, Valdes-Herrera, Jose P., Galazky, Imke and Nestor, Peter J. (2017). The whole-brain pattern of magnetic susceptibility perturbations in Parkinson's disease. Brain, 140 (1), 118-131. doi: 10.1093/brain/aww278

The whole-brain pattern of magnetic susceptibility perturbations in Parkinson's disease

2017

Journal Article

The European DTI study on dementia — a multicenter DTI and MRI study on Alzheimer's disease and mild cognitive impairment

Brueggen, Katharina, Grothe, Michel J., Dyrba, Martin, Fellgiebel, Andreas, Fischer, Florian, Filippi, Massimo, Agosta, Federica, Nestor, Peter, Meisenzahl, Eva, Blautzik, Janusch, Froelich, Lutz, Hausner, Lucrezia, Bokde, Arun L. W., Frisoni, Giovanni, Pievani, Michela, Kloeppel, Stefan, Prvulovic, David, Barkhof, Frederik, Pouwels, Petra J. W., Schroeder, Johannes, Hampel, Harald, Hauenstein, Karlheinz and Teipel, Stefan (2017). The European DTI study on dementia — a multicenter DTI and MRI study on Alzheimer's disease and mild cognitive impairment. NeuroImage, 144 (B), 305-308. doi: 10.1016/j.neuroimage.2016.03.067

The European DTI study on dementia — a multicenter DTI and MRI study on Alzheimer's disease and mild cognitive impairment

2017

Book Chapter

Frontotemporal dementia

Nestor, Peter J. (2017). Frontotemporal dementia. Dementia. (pp. 749-758) edited by David Ames, John T. O'Brien and Alistair Burns. Boca Raton, FL, United States: CRC Press. doi: 10.1201/9781315381572

Frontotemporal dementia

2016

Journal Article

High-resolution characterisation of the aging brain using simultaneous quantitative susceptibility mapping (QSM) and R2* measurements at 7 T

Betts, Matthew J., Acosta-Cabronero, Julio, Cardenas-Blanco, Arturo, Nestor, Peter J. and Duezel, Emrah (2016). High-resolution characterisation of the aging brain using simultaneous quantitative susceptibility mapping (QSM) and R2* measurements at 7 T. NeuroImage, 138, 43-63. doi: 10.1016/j.neuroimage.2016.05.024

High-resolution characterisation of the aging brain using simultaneous quantitative susceptibility mapping (QSM) and R2* measurements at 7 T

2016

Journal Article

Quantifying disease progression in ALS using peripheral nerve sonography

Schreiber, S., Dannhardt-Stieger, V., Henkel, D., Debska-Vielhaber, G., Machts, J., Abdulla, S., Kropf, S., Kollewe, K., Petri, S., Heinze, H. J., Dengler, R., Nestor, P. J. and Vielhaber, S. (2016). Quantifying disease progression in ALS using peripheral nerve sonography. Muscle and Nerve, 54 (3), 391-397. doi: 10.1002/mus.25066

Quantifying disease progression in ALS using peripheral nerve sonography

2016

Journal Article

The pattern of amyloid accumulation in the brains of adults with Down syndrome

Annus, Tiina, Wilson, Liam R., Hong, Young T., Acosta-Cabronero, Julio, Fryer, Tim D., Cardenas-Blanco, Arturo, Smith, Robert, Boros, Istvan, Coles, Jonathan P., Aigbirhio, Franklin I., Menon, David K., Zaman, Shahid H., Nestor, Peter J. and Holland, Anthony J. (2016). The pattern of amyloid accumulation in the brains of adults with Down syndrome. Alzheimers & Dementia, 12 (5), 538-545. doi: 10.1016/j.jalz.2015.07.490

The pattern of amyloid accumulation in the brains of adults with Down syndrome

2016

Book Chapter

Bedside assessment of cognition

Sajjadi, S. A. and Nestor, P. J. (2016). Bedside assessment of cognition. Oxford Textbook of Cognitive Neurology and Dementia. (pp. 105-112) edited by Hussain, M. and Schott, J. M.. Oxford University Press, Oxford, UK: OUP. doi: 10.1093/med/9780199655946.003.0010

Bedside assessment of cognition

2016

Journal Article

Structural and diffusion imaging versus clinical assessment to monitor amyotrophic lateral sclerosis

Cardenas-Blanco, Arturo, Machts, Judith, Acosta-Cabronero, Julio, Kaufmann, Joern, Abdulla, Susanne, Kollewe, Katja, Petri, Susanne, Schreiber, Stefanie, Heinze, Hans-Jochen, Dengler, Reinhard, Vielhaber, Stefan and Nestor, Peter J. (2016). Structural and diffusion imaging versus clinical assessment to monitor amyotrophic lateral sclerosis. Neuroimage: Clinical, 11, 408-414. doi: 10.1016/j.nicl.2016.03.011

Structural and diffusion imaging versus clinical assessment to monitor amyotrophic lateral sclerosis

2016

Journal Article

In vivo MRI mapping of brain iron deposition across the adult lifespan

Acosta-Cabronero, Julio, Betts, Matthew J., Cardenas-Blanco, Arturo, Yang, Shan and Nestor, Peter J. (2016). In vivo MRI mapping of brain iron deposition across the adult lifespan. Journal of Neuroscience, 36 (2), 364-374. doi: 10.1523/JNEUROSCI.1907-15.2016

In vivo MRI mapping of brain iron deposition across the adult lifespan

2015

Journal Article

Hereditary diffuse leukoencephalopathy with spheroids (HDLS) with a novel CSF1R mutation and spinal cord involvement

Koertvelyessy, Peter, Kraegeloh-Mann, Ingeborg, Mawrin, Christian, Heinze, Hans-Jochen, Bittner, Daniel, Wieland, Ilse, Zenker, Martin and Nestor, Peter (2015). Hereditary diffuse leukoencephalopathy with spheroids (HDLS) with a novel CSF1R mutation and spinal cord involvement. Journal of the Neurological Sciences, 358 (1-2), 515-517. doi: 10.1016/j.jns.2015.09.370

Hereditary diffuse leukoencephalopathy with spheroids (HDLS) with a novel CSF1R mutation and spinal cord involvement

2015

Journal Article

SECT and MAST: new tests to assess grammatical abilities in primary progressive aphasia

Billette, Ornella V., Sajjadi, Seyed A., Patterson, Karalyn and Nestor, Peter J. (2015). SECT and MAST: new tests to assess grammatical abilities in primary progressive aphasia. Aphasiology, 29 (10), 1135-1151. doi: 10.1080/02687038.2015.1037822

SECT and MAST: new tests to assess grammatical abilities in primary progressive aphasia

2015

Journal Article

Basal forebrain and hippocampus as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment-a multicenter DTI and volumetry study

Brueggen, Katharina, Dyrba, Martin, Barkhof, Frederik, Hausner, Lucrezia, Filippi, Massimo, Nestor, Peter J., Hauenstein, Karlheinz, Kloeppel, Stefan, Grothe, Michel J., Kasper, Elisabeth and Teipel, Stefan J. (2015). Basal forebrain and hippocampus as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment-a multicenter DTI and volumetry study. Journal of Alzheimers Disease, 48 (1), 197-204. doi: 10.3233/JAD-150063

Basal forebrain and hippocampus as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment-a multicenter DTI and volumetry study

2015

Journal Article

Peripheral nerve ultrasound in amyotrophic lateral sclerosis phenotypes

Schreiber, Stefanie, Abdulla, Susanne, Debska-Vielhaber, Grazyna, Machts, Judith, Dannhardt-Stieger, Verena, Feistner, Helmut, Oldag, Andreas, Goertler, Michael, Petri, Susanne, Kollewe, Katja, Kropf, Siegfried, Schreiber, Frank, Heinze, Hans-Jochen, Dengler, Reinhard, Nestor, Peter J. and Vielhaber, Stefan (2015). Peripheral nerve ultrasound in amyotrophic lateral sclerosis phenotypes. Muscle & Nerve, 51 (5), 669-675. doi: 10.1002/mus.24431

Peripheral nerve ultrasound in amyotrophic lateral sclerosis phenotypes

2014

Journal Article

A new fast accurate nonlinear medical image registration program including surface preserving regularization

Gruslys, Audrunas, Acosta-Cabronero, Julio, Nestor, Peter J., Williams, Guy B. and Ansorge, Richard E. (2014). A new fast accurate nonlinear medical image registration program including surface preserving regularization. IEEE Transactions on Medical Imaging, 33 (11) A6, 2118-2127. doi: 10.1109/TMI.2014.2332370

A new fast accurate nonlinear medical image registration program including surface preserving regularization

2014

Journal Article

Hippocampal degeneration in patients with amyotrophic lateral sclerosis

Abdulla, Susanne, Machts, Judith, Kaufmann, Joern, Patrick, Karina, Kollewe, Katja, Dengler, Reinhard, Heinze, Hans-Jochen, Petri, Susanne, Vielhaber, Stefan and Nestor, Peter J. (2014). Hippocampal degeneration in patients with amyotrophic lateral sclerosis. Neurobiology of Aging, 35 (11), 2639-2645. doi: 10.1016/j.neurobiolaging.2014.05.035

Hippocampal degeneration in patients with amyotrophic lateral sclerosis

2014

Journal Article

Comparing voxel-based iterative sensitivity and voxel-based morphometry to detect abnormalities in T2-weighted MRI

Diaz-de-Grenu, Lara Z., Acosta-Cabronero, Julio, Williams, Guy B. and Nestor, Peter J. (2014). Comparing voxel-based iterative sensitivity and voxel-based morphometry to detect abnormalities in T2-weighted MRI. NeuroImage, 100, 379-384. doi: 10.1016/j.neuroimage.2014.06.030

Comparing voxel-based iterative sensitivity and voxel-based morphometry to detect abnormalities in T2-weighted MRI

Funding

Current funding

  • 2024 - 2026
    Disambiguating Parkinson's disease from disorders with mimicking symptoms using ultra-high-field (7 Tesla) multi-modal MRI
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2023 - 2024
    Use of advanced magnetic resonance imaging (MRI) technology to improve understanding and diagnosis of the major neurodegenerative diseases
    Metro North Hospital and Health Service
    Open grant

Supervision

Availability

Professor Peter Nestor is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    The evolution of cognitive deficits in Lewy body disorders and related degenerative diseases.

    Principal Advisor

    Other advisors: Associate Professor John O'Sullivan

  • Doctor Philosophy

    The `What¿ and `Where¿ of Visual Processing in Neurodegeneration: The essential yet overlooked component of diagnostic testing in dementia

    Principal Advisor

    Other advisors: Professor Jason Mattingley

  • Doctor Philosophy

    Diagnostic specificity in frontotemporal dementia

    Principal Advisor

  • Doctor Philosophy

    Cognitive switching in ageing and preclinical neurodegenerative disorders

    Associate Advisor

    Other advisors: Professor Gail Robinson

Completed supervision

Media

Enquiries

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