
Overview
Background
Prof Nestor joined the Queensland Brain Institute in October/2017 and has a conjoint appointment as a cognitive neurologist at Mater Misericordiae Ltd (Mater Hospital).
His particular interests include understanding the earliest stages of Alzheimer's disease (i.e. before dementia is established); atypical forms of dementia with a particular focus on primary progressive aphasia and dementias related to Parkinson's and Lewy body diseases; and improving differential diagnosis between the major categories of neurodegenerative diseases.
He works on development of neuropsychological tests of cognition, both to accurately track change over time and improve diagnostic accuracy between the major diseases causing dementia. He also uses multi-modal imaging (magnetic resonance imaging [MRI] and positron emission tomography [PET]) to understand the sequence of events occurring in degenerative brain diseases (particularly Alzheimer's disease, frontotemporal dementia, Parkinson's disease, motor neuron disease [ALS], progressive supranuclear palsy [PSP] and corticobasal degeneration [CBD]) and identify novel biomarkers. A major focus of his is on developing novel approaches to MR imaging for single subject pathological diagnoses that can be exported into the everyday clinical setting; recent examples include diffusion tensor imaging to identify PSP and CBD (Sajjadi et al, 2013) and quantitative susceptibility mapping in Parkinson's disease (Acosta-Cabornero et al, 2013).
Availability
- Professor Peter Nestor is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, University of Melbourne
- Doctor of Philosophy, University of Cambridge
Research interests
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Cognitive neurology
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frontotemporal lobar degeneration
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progressive aphasia
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Alzheimer's disease
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Neurodegenerative diseases
Works
Search Professor Peter Nestor’s works on UQ eSpace
2018
Journal Article
Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer's disease (DELCODE)
Jessen, Frank, Spottke, Annika, Boecker, Henning, Brosseron, Frederic, Buerger, Katharina, Catak, Cihan, Fliessbach, Klaus, Franke, Christiana, Fuentes, Manuel, Heneka, Michael T., Janowitz, Daniel, Kilimann, Ingo, Laske, Christoph, Menne, Felix, Nestor, Peter, Peters, Oliver, Priller, Josef, Pross, Verena, Ramirez, Alfredo, Schneider, Anja, Speck, Oliver, Spruth, Eike Jakob, Teipel, Stefan, Vukovich, Ruth, Westerteicher, Christine, Wiltfang, Jens, Wolfsgruber, Steffen, Wagner, Michael and Düzel, Emrah (2018). Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer's disease (DELCODE). Alzheimer's Research and Therapy, 10 (1) 15. doi: 10.1186/s13195-017-0314-2
2018
Journal Article
Peripheral nerve atrophy together with higher CSF progranulin indicate axonal damage in ALS
Schreiber, S., Debska-Vielhaber, G., Abdulla, S., Machts, J., Schreiber, F., Kropf, S., KÖrtvelyessy, P., KÖrner, S., Kollewe, K., Petri, S., Dengler, R., Kunz, W. S., Nestor, P. J. and Vielhaber, S. (2018). Peripheral nerve atrophy together with higher CSF progranulin indicate axonal damage in ALS. Muscle and Nerve, 57 (2), 273-278. doi: 10.1002/mus.25682
2018
Journal Article
CSF total tau levels are associated with hippocampal novelty irrespective of hippocampal volume
Düzel, Emrah, Berron, David, Schütze, Hartmut, Cardenas-Blanco, Arturo, Metzger, Coraline, Betts, Matthew, Ziegler, Gabriel, Chen, Yi, Dobisch, Laura, Bittner, Daniel, Glanz, Wenzel, Reuter, Martin, Spottke, Annika, Rudolph, Janna, Brosseron, Frederic, Buerger, Katharina, Janowitz, Daniel, Fliessbach, Klaus, Heneka, Michael, Laske, Christoph, Buchmann, Martina, Nestor, Peter, Peters, Oliver, Diesing, Dominik, Li, Siyao, Priller, Josef, Spruth, Eike Jakob, Altenstein, Slawek, Ramirez, Alfredo ... Jessen, Frank (2018). CSF total tau levels are associated with hippocampal novelty irrespective of hippocampal volume. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 10 (C), 782-790. doi: 10.1016/j.dadm.2018.10.003
2017
Journal Article
Tau plasma levels in subjective cognitive decline: Results from the DELCODE study
Müller, Stephan, Preische, Oliver, Göpfert, Jens C., Yañez, Viviana A. Carcamo, Joos, Thomas O., Boecker, Henning, Düzel, Emrah, Falkai, Peter, Priller, Josef, Buerger, Katharina, Catak, Cihan, Janowitz, Daniel, Heneka, Michael T., Brosseron, Frederic, Nestor, Peter, Peters, Oliver, Menne, Felix, Schipke, Carola G., Schneider, Anja, Spottke, Annika, Fließbach, Klaus, Kilimann, Ingo, Teipel, Stefan, Wagner, Michael, Wiltfang, Jens, Jessen, Frank and Laske, Christoph (2017). Tau plasma levels in subjective cognitive decline: Results from the DELCODE study. Scientific Reports, 7 (1) 9529. doi: 10.1038/s41598-017-08779-0
2017
Journal Article
Data-driven classification of patients with primary progressive aphasia
Hoffman, Paul, Sajjadi, Seyed Ahmad, Patterson, Karalyn and Nestor, Peter J. (2017). Data-driven classification of patients with primary progressive aphasia. Brain and Language, 174, 86-93. doi: 10.1016/j.bandl.2017.08.001
2017
Journal Article
Dementia of the personality
Nestor, Peter J. (2017). Dementia of the personality. Medical Journal of Australia, 207 (7), 286-287. doi: 10.5694/mja17.00667
2017
Journal Article
Reply
Sajjadi, S. A. and Nestor, P. J. (2017). Reply. American Journal of Neuroradiology, 38 (9), E64-E64. doi: 10.3174/ajnr.A5261
2017
Journal Article
Brain-predicted age in Down syndrome is associated with beta amyloid deposition and cognitive decline
Cole, James H., Annus, Tiina, Wilson, Liam R., Remtulla, Ridhaa, Hong, Young T., Fryer, Tim D., Acosta-Cabronero, Julio, Cardenas-Blanco, Arturo, Smith, Robert, Menon, David K., Zaman, Shahid H., Nestor, Peter J. and Holland, Anthony J. (2017). Brain-predicted age in Down syndrome is associated with beta amyloid deposition and cognitive decline. Neurobiology of Aging, 56, 41-49. doi: 10.1016/j.neurobiolaging.2017.04.006
2017
Journal Article
Consensus classification of posterior cortical atrophy
Crutch, Sebastian J., Schott, Jonathan M., Rabinovici, Gil D., Murray, Melissa, Snowden, Julie S., van der Flier, Wiesje M., Dickerson, Bradford C., Vandenberghe, Rik, Ahmed, Samrah, Bak, Thomas H., Boeve, Bradley F., Butler, Christopher, Cappa, Stefano F., Ceccaldi, Mathieu, de Souza, Leonardo Cruz, Dubois, Bruno, Felician, Olivier, Galasko, Douglas, Graff-Radford, Jonathan, Graff-Radford, Neill R., Hof, Patrick R., Krolak-Salmon, Pierre, Lehmann, Manja, Magnin, Eloi, Mendez, Mario F., Nestor, Peter J., Onyike, Chiadi U., Pelak, Victoria S., Pijnenburg, Yolande ... Fox, Nick C. (2017). Consensus classification of posterior cortical atrophy. Alzheimers & Dementia, 13 (8), 870-884. doi: 10.1016/j.jalz.2017.01.014
2017
Journal Article
Semantic word category processing in semantic dementia and posterior cortical atrophy
Shebani, Zubaida, Patterson, Karalyn, Nestor, Peter J., Diaz-de-Grenu, Lara Z., Dawson, Kate and Pulvermüller, Friedemann (2017). Semantic word category processing in semantic dementia and posterior cortical atrophy. Cortex, 93, 92-106. doi: 10.1016/j.cortex.2017.04.016
2017
Journal Article
Which ante mortem clinical features predict progressive supranuclear palsy pathology?
Respondek, Gesine, Kurz, Carolin, Arzberger, Thomas, Compta, Yaroslau, Englund, Elisabet, Ferguson, Leslie W., Gelpi, Ellen, Giese, Armin, Irwin, David J., Meissner, Wassilios G., Nilsson, Christer, Pantelyat, Alexander, Rajput, Alex, van Swieten, John C., Troakes, Claire, Josephs, Keith A., Lang, Anthony E., Mollenhauer, Brit, Mueller, Ulrich, Whitwell, Jennifer L., Antonini, Angelo, Bhatia, Kailash P., Bordelon, Yvette, Corvol, Jean-Christophe, Colosimo, Carlo, Dodel, Richard, Grossman, Murray, Kassubek, Jan, Krismer, Florian ... Hoeglinger, Guenter U. (2017). Which ante mortem clinical features predict progressive supranuclear palsy pathology?. Movement Disorders, 32 (7), 995-1005. doi: 10.1002/mds.27034
2017
Journal Article
Beyond clinical syndromes in primary progressive aphasia
Knopman, David S. and Nestor, Peter J. (2017). Beyond clinical syndromes in primary progressive aphasia. Neurology, 88 (24), 2244-2245. doi: 10.1212/WNL.0000000000004041
2017
Journal Article
Clinical diagnosis of progressive supranuclear palsy: the movement disorder society criteria
Hoeglinger, Guenter U., Respondek, Gesine, Stamelou, Maria, Kurz, Carolin, Josephs, Keith A., Lang, Anthony E., Mollenhauer, Brit, Mueller, Ulrich, Nilsson, Christer, Whitwell, Jennifer L., Arzberger, Thomas, Englund, Elisabet, Gelpi, Ellen, Giese, Armin, Irwin, David J., Meissner, Wassilios G., Pantelyat, Alexander, Rajput, Alex, van Swieten, John C., Troakes, Claire, Antonini, Angelo, Bhatia, Kailash P., Bordelon, Yvette, Compta, Yaroslau, Corvol, Jean-Christophe, Colosimo, Carlo, Dickson, Dennis W., Dodel, Richard, Ferguson, Leslie ... Litvan, Irene (2017). Clinical diagnosis of progressive supranuclear palsy: the movement disorder society criteria. Movement Disorders, 32 (6), 853-864. doi: 10.1002/mds.26987
2017
Journal Article
Can MRI visual assessment differentiate the variants of primary-progressive aphasia?
Sajjadi, S. A., Sheikh-Bahaei, N., Cross, J., Gillard, J. H., Scoffings, D. and Nestor, P. J. (2017). Can MRI visual assessment differentiate the variants of primary-progressive aphasia?. American Journal of Neuroradiology, 38 (5), 954-960. doi: 10.3174/ajnr.A5126
2017
Journal Article
The Down syndrome brain in the presence and absence of fibrillar β-amyloidosis
Annus, Tiina, Wilson, Liam R., Acosta-Cabronero, Julio, Cardenas-Blanco, Arturo, Hong, Young T., Fryer, Tim D., Coles, Jonathan P., Menon, David K., Zaman, Shahid H., Holland, Anthony J. and Nestor, Peter J. (2017). The Down syndrome brain in the presence and absence of fibrillar β-amyloidosis. Neurobiology of Aging, 53, 11-19. doi: 10.1016/j.neurobiolaging.2017.01.009
2017
Journal Article
Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis
Smith, Bradley N., Topp, Simon D., Fallini, Claudia, Shibata, Hideki, Chen, Han-Jou, Troakes, Claire, King, Andrew, Ticozzi, Nicola, Kenna, Kevin P., Soragia-Gkazi, Athina, Miller, Jack W., Sato, Akane, Dias, Diana Marques, Jeon, Maryangel, Vance, Caroline, Wong, Chun Hao, de Majo, Martina, Kattuah, Wejdan, Mitchell, Jacqueline C., Scotter, Emma L., Parkin, Nicholas W., Sapp, Peter C., Nolan, Matthew, Nestor, Peter J., Simpson, Michael, Weale, Michael, Lek, Monkel, Baas, Frank, de Jong, J. M. Vianney ... Shaw, Christopher E. (2017). Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis. Science Translational Medicine, 9 (388) aad9157, eaad9157. doi: 10.1126/scitranslmed.aad9157
2017
Journal Article
The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: Consensus document of the Joint Program for Neurodegenerative Diseases Working Group
Costa, Alberto, Bak, Thomas, Caffarra, Paolo, Caltagirone, Carlo, Ceccaldi, Mathieu, Collette, Fabienne, Crutch, Sebastian, Della Sala, Sergio, Demonet, Jean Francois, Dubois, Bruno, Duzel, Emrah, Nestor, Peter, Papageorgiou, Sokratis G., Salmon, Eric, Sikkes, Sietske, Tiraboschi, Pietro, van der Flier, Wiesje M., Visser, Pieter Jelle and Cappa, Stefano F. (2017). The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: Consensus document of the Joint Program for Neurodegenerative Diseases Working Group. Alzheimers Research & Therapy, 9 (1) 27. doi: 10.1186/s13195-017-0254-x
2017
Journal Article
The whole-brain pattern of magnetic susceptibility perturbations in Parkinson's disease
Acosta-Cabronero, Julio, Cardenas-Blanco, Arturo, Betts, Matthew J., Butryn, Michaela, Valdes-Herrera, Jose P., Galazky, Imke and Nestor, Peter J. (2017). The whole-brain pattern of magnetic susceptibility perturbations in Parkinson's disease. Brain, 140 (1), 118-131. doi: 10.1093/brain/aww278
2017
Journal Article
The European DTI study on dementia — a multicenter DTI and MRI study on Alzheimer's disease and mild cognitive impairment
Brueggen, Katharina, Grothe, Michel J., Dyrba, Martin, Fellgiebel, Andreas, Fischer, Florian, Filippi, Massimo, Agosta, Federica, Nestor, Peter, Meisenzahl, Eva, Blautzik, Janusch, Froelich, Lutz, Hausner, Lucrezia, Bokde, Arun L. W., Frisoni, Giovanni, Pievani, Michela, Kloeppel, Stefan, Prvulovic, David, Barkhof, Frederik, Pouwels, Petra J. W., Schroeder, Johannes, Hampel, Harald, Hauenstein, Karlheinz and Teipel, Stefan (2017). The European DTI study on dementia — a multicenter DTI and MRI study on Alzheimer's disease and mild cognitive impairment. NeuroImage, 144 (B), 305-308. doi: 10.1016/j.neuroimage.2016.03.067
2017
Book Chapter
Frontotemporal dementia
Nestor, Peter J. (2017). Frontotemporal dementia. Dementia. (pp. 749-758) edited by David Ames, John T. O'Brien and Alistair Burns. Boca Raton, FL, United States: CRC Press. doi: 10.1201/9781315381572
Supervision
Availability
- Professor Peter Nestor is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
The `What¿ and `Where¿ of Visual Processing in Neurodegeneration: The essential yet overlooked component of diagnostic testing in dementia
Principal Advisor
Other advisors: Professor Jason Mattingley
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Doctor Philosophy
Diagnostic specificity in frontotemporal dementia
Principal Advisor
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Doctor Philosophy
The evolution of cognitive deficits in Lewy body disorders and related degenerative diseases.
Principal Advisor
Other advisors: Associate Professor John O'Sullivan
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Doctor Philosophy
Clinical utility of autobiographical memory in dementia diagnoses
Principal Advisor
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Doctor Philosophy
Attentional Switching in Healthy Ageing and Neurodegenerative Disorders
Associate Advisor
Other advisors: Professor Gail Robinson
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Doctor Philosophy
Cognitive switching in ageing and preclinical neurodegenerative disorders
Associate Advisor
Other advisors: Professor Gail Robinson
Completed supervision
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2024
Doctor Philosophy
The `What' and `Where' of Visual Processing in Neurodegeneration: The essential yet overlooked component of diagnostic testing in dementia
Principal Advisor
Other advisors: Professor Jason Mattingley
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2021
Doctor Philosophy
Neuroimaging of Traumatic Brain Injury and Dementia: Bridging the link
Associate Advisor
Other advisors: Associate Professor Fatima Nasrallah
Media
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