Overview
Background
He is a Research Fellow with the Microbial Biology and Metagenomics group within the Immunology Program of the University of Queensland Frazer Institute and an honorary fellowship with The Commonwealth Scientific and Industrial Research Organisation (CSIRO, 2019-2021). His PhD research involved designing and applying DNA transfer systems for heterologous protein expression in Lactobacillus spp. He moved to The Ohio State University, USA to conduct postdoctoral research in gut microbiology, focusing on fibre-degrading bacteria and their production of multi-protein complexes supporting this process. He was recruited to join CSIRO (Brisbane) to undertake collaborative research projects for the “Colorectal Cancer and Gut Health” Theme of their Preventative Health Flagship Research Program. His contributions during this time were to develop further and use the DNA microarray technology he had pioneered to examine the stool and mucosa-associated microbiota communities in Crohn’s disease with French and Australian collaborators. These efforts led to several highly cited and high-impact publications in key medical journals, recognised for providing some of the first insights into the critical bacterial taxa that underpin the microbial “dysbiosis” now considered a hallmark of Crohn’s disease. In early 2019, he accepted a position with professor Morrison’s group as part of my ongoing collaborations with Melbourne University in Crohn’s disease research supported via the Helmsley Charitable Trust. He is providing leadership in using a novel ex-vivo combination of gut microbe culture and metagenomic sequencing for the first deep functional characterisation of the Crohn’s disease mucosa-associated microbiota. His development and implementation of innovative molecular biology and “omics” approach help better understand complex microbial gut systems relevant to human health.
Availability
- Dr Seungha Kang is:
- Available for supervision
Qualifications
- Doctor of Philosophy, Seoul National University
Works
Search Professor Seungha Kang’s works on UQ eSpace
2021
Journal Article
In vitro assessment of rumen inocula between Jersey and Holstein steers with forage and concentrate substrates
Kim, Seon-Ho, Islam, Mahfuzul, Son, A-Rang, Lee, Sung-Sill, Kang, Seung-Ha, Cho, Yong-Il, Park, Kwang-Wook and Lee, Sang-Suk (2021). In vitro assessment of rumen inocula between Jersey and Holstein steers with forage and concentrate substrates. Journal of Agriculture and Life Science, 55 (3), 89-96. doi: 10.14397/jals.2021.55.3.89
2021
Journal Article
Novel strain-level resolution of Crohn’s disease mucosa-associated microbiota via an ex vivo combination of microbe culture and metagenomic sequencing
Teh, J. J., Berendsen, E. M., Hoedt, E. C., Kang, S., Zhang, J., Zhang, F., Liu, Q., Hamilton, A. L., Wilson-O’Brien, A., Ching, J., Sung, J. J. Y., Yu, J., Ng, S. C., Kamm, M. A. and Morrison, M. (2021). Novel strain-level resolution of Crohn’s disease mucosa-associated microbiota via an ex vivo combination of microbe culture and metagenomic sequencing. The ISME Journal, 15 (11), 3326-3338. doi: 10.1038/s41396-021-00991-1
2021
Conference Publication
Food additives enhance pro-inflammatory bacterial growth in Crohn's disease mucosa-associated microbiota. The Enigma Study
Kang, Seungha, de Klerk, Ashley, Noon, Ebony, Teh, Jing Jie, Zhang, Jingwan, Zhang, Fen, Liu, Qin, Hamilton, Amy L., Wilson-O'Brien, Amy, Trakman, Gina L., Lin, Winnie Y., Ching, Jessica Y., Sung, Joseph J., Yu, Jun, Ng, Siew C., Kamm, Michael A. and Morrison, Mark (2021). Food additives enhance pro-inflammatory bacterial growth in Crohn's disease mucosa-associated microbiota. The Enigma Study. DDW 2021, Online, 21-23 May 2021. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(21)01036-2
2021
Conference Publication
Sa533 Novel characterization of the secretomes of crohn's disease mucosa-associated microbiota, and their modulation of inflammation through nf-κb signalling. The Enigma Study
Teh, Jing Jie, Kang, Seungha, Schooth, Lauren F., Loayza, Jeimy Johana Jimenez, Zhang, Jingwan, Zhang, Fen, Liu, Qin, Hamilton, Amy L., Wilson-O'Brien, Amy, Ching, Jessica Y., Sung, Joseph J., Yu, Jun, Ng, Siew C., Kamm, Michael A. and Morrison, Mark (2021). Sa533 Novel characterization of the secretomes of crohn's disease mucosa-associated microbiota, and their modulation of inflammation through nf-κb signalling. The Enigma Study. DDW 2021, Virtual, 21-23 May 2021. Philadelphia, PA USA: Elsevier. doi: 10.1016/s0016-5085(21)01989-2
2021
Journal Article
Seasonal influence on rumen microbiota, rumen fermentation, and enteric methane emissions of Holstein and Jersey steers under the same total mixed ration
Islam, Mahfuzul, Kim, Seon-Ho, Son, A-Rang, Ramos, Sonny C., Jeong, Chang-Dae, Yu, Zhongtang, Kang, Seung Ha, Cho, Yong-Il, Lee, Sung-Sill, Cho, Kwang-Keun and Lee, Sang-Suk (2021). Seasonal influence on rumen microbiota, rumen fermentation, and enteric methane emissions of Holstein and Jersey steers under the same total mixed ration. Animals, 11 (4) 1184, 1-22. doi: 10.3390/ani11041184
2021
Journal Article
Diet transition from high-forage to high-concentrate alters rumen bacterial community composition, epithelial transcriptomes and ruminal fermentation parameters in dairy cows
Ramos, Sonny C., Jeong, Chang Dae, Mamuad, Lovelia L., Kim, Seon Ho, Kang, Seung Ha, Kim, Eun Tae, Cho, Yong Il, Lee, Sung Sill and Lee, Sang Suk (2021). Diet transition from high-forage to high-concentrate alters rumen bacterial community composition, epithelial transcriptomes and ruminal fermentation parameters in dairy cows. Animals, 11 (3) 838, 838-23. doi: 10.3390/ani11030838
2020
Conference Publication
Self-reported non-celiac wheat sensitivity in patients with chronic unexplained (functional) gastrointestinal symptoms: gut function, immune activation and duodenal mucosa associated microbiome
Shah, Ayesha, Talley, Nicholas J., Kang, Seungha, Do, Anh, Walker, Marjorie M., Shanahan, Erin R., Koloski, Natasha A., Jones, Michael P., Keely, Simon, Morrison, Mark and Holtmann, Gerald J. (2020). Self-reported non-celiac wheat sensitivity in patients with chronic unexplained (functional) gastrointestinal symptoms: gut function, immune activation and duodenal mucosa associated microbiome. AGA 2020, Online, 2020. Philadelphia, PA United States: Elsevier . doi: 10.1016/s0016-5085(20)31900-4
2020
Conference Publication
Microbiota and viruence factors associated with Crohn's Disease recurrence revealed at strain-level resolution by novel combination of microbe culture and metagenomic sequencing (mc-mgs). The Enigma Study
Teh, Jing Jie, Kang, Seungha, Murtaza, Nida, Zhang, Jingwan, Zhang, Fen, Liu, Qin, Hamilton, Amy L., Wilson-O'Brien, Amy, Ching, Jessica Y., Sung, Joseph J., Yu, Jun, Ng, Siew C., Kamm, Michael A. and Morrison, Mark (2020). Microbiota and viruence factors associated with Crohn's Disease recurrence revealed at strain-level resolution by novel combination of microbe culture and metagenomic sequencing (mc-mgs). The Enigma Study. AGA 2020, Online, 2020. Philadelphia, PA United States: Elsevier . doi: 10.1016/s0016-5085(20)33265-0
2020
Journal Article
Characterisation and survey in cattle of a rumen Pyrimadobacter sp. which degrades the plant toxin fluoroacetate
Kang, Seungha, Khan, Shahjalal, Webb, Rick, Denman, Stuart and McSweeney, Chris (2020). Characterisation and survey in cattle of a rumen Pyrimadobacter sp. which degrades the plant toxin fluoroacetate. FEMS Microbiology Ecology, 96 (7) fiaa077, 1-11. doi: 10.1093/femsec/fiaa077
2020
Conference Publication
Variations of the mucosa associated microbiota along the human gastrointestinal tract in health and inflammatory bowel disease
Shah, Ayesha, Kang, Seungha, Tyson, Gene, Zaugg, Julian, Hugenholtz, Phil, Morrison, Mark and Holtmann, Gerald J. (2020). Variations of the mucosa associated microbiota along the human gastrointestinal tract in health and inflammatory bowel disease. Crohn's and Colitis Congress, Austin, TX, United States, 23-25 January 2020. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(20)32052-7
2020
Journal Article
Purified plant cell walls with adsorbed polyphenols alter porcine faecal bacterial communities during in vitro fermentation
Grant, Lucas J., Mikkelsen, Deirdre, Phan, Anh Dao T., Kang, Seungha, Ouwerkerk, Diane, Klieve, Athol V., Gidley, Mike J. and Williams, Barbara (2020). Purified plant cell walls with adsorbed polyphenols alter porcine faecal bacterial communities during in vitro fermentation. Food and Function, 11 (1), 834-845. doi: 10.1039/c9fo02428j
2020
Conference Publication
Self-reported non-celiac wheat sensitivity (NCWS) in patients with chronic unexplained (functional) gastrointestinal symptoms
Shah, Ayesha, Talley, Nicholas, Kang, Seungha, Do, Anh, Walker, Marjorie, Koloski, Natasha, Jones, Michael, Keely, Simon, Morrison, Mark and Holtmann, Gerald (2020). Self-reported non-celiac wheat sensitivity (NCWS) in patients with chronic unexplained (functional) gastrointestinal symptoms. Meeting of the Federation of Neurogastroenterology and Motility, Adelaide, SA Australia, 25 – 28 March 2020. Chichester, West Sussex United Kingdom: Wiley-Blackwell.
2019
Journal Article
Draft genome sequence and annotation of sporanaerobacter acetigenes strain F-12, isolated from a cattle rumen
Kang, Seungha, Denman, Stuart, Tahmasbi, Reza and McSweeney, Chris (2019). Draft genome sequence and annotation of sporanaerobacter acetigenes strain F-12, isolated from a cattle rumen. Microbiology Resource Announcements, 8 (30) e00634-19. doi: 10.1128/MRA.00634-19
2019
Journal Article
Draft genome sequence and annotation of Oribacterium sp. strain C9, isolated from a cattle rumen
Kang, Seungha, Denman, Stuart and McSweeney, Chris (2019). Draft genome sequence and annotation of Oribacterium sp. strain C9, isolated from a cattle rumen. Microbiology Resource Announcements, 8 (13) e01562-18. doi: 10.1128/mra.01562-18
2016
Journal Article
Soluble arabinoxylan enhances large intestinal microbial health biomarkers in pigs fed a red meat-containing diet
Williams, Barbara A., Zhang, Dagong, Lisle, Allan T., Mikkelsen, Deirdre, McSweeney C. S., Kang, Seungha, Bryden, Wayne L. and Gidley, Michael J. (2016). Soluble arabinoxylan enhances large intestinal microbial health biomarkers in pigs fed a red meat-containing diet. Nutrition, 32 (4), 491-497. doi: 10.1016/j.nut.2015.10.008
2016
Journal Article
Addition of arabinoxylan and mixed linkage glucans in porcine diets affects the large intestinal bacterial populations
Gorham, John B., Kang, Seungha, Williams, Barbara A., Grant, Lucas J., McSweeney, Christopher S., Gidley, Michael J. and Mikkelsen, Deirdre (2016). Addition of arabinoxylan and mixed linkage glucans in porcine diets affects the large intestinal bacterial populations. European Journal of Nutrition, 56 (6), 1-14. doi: 10.1007/s00394-016-1263-4
2016
Journal Article
Cloning and characterization of an endoglucanase gene from Actinomyces sp. Korean native goat 40
Kim, Sung Chan, Kang, Seung Ha, Choi, Eun Young, Hong, Yeon Hee, Bok, Jin Duck, Kim, Jae Yeong, Lee, Sang Suk, Choi, Yun Jaie, Choi, In Soon and Cho, Kwang Keun (2016). Cloning and characterization of an endoglucanase gene from Actinomyces sp. Korean native goat 40. Asian-Australasian Journal of Animal Sciences, 29 (1), 126-133. doi: 10.5713/ajas.15.0616
2015
Journal Article
Association between specific mucosa-associated microbiota in Crohn's disease at the time of resection and subsequent disease recurrence: a pilot study
De Cruz, Peter, Kang, Seungha, Wagner, Josef, Buckley, Michael, Sim, Winnie H., Prideaux, Lani, Lockett, Trevor, McSweeney, Chris, Morrison, Mark, Kirkwood, Carl D. and Kamm, Michael A. (2015). Association between specific mucosa-associated microbiota in Crohn's disease at the time of resection and subsequent disease recurrence: a pilot study. Journal of Gastroenterology and Hepatology, 30 (2), 268-278. doi: 10.1111/jgh.12694
2014
Journal Article
Characterization, Gene Cloning, and Sequencing of a Fungal Phytase, PhyA, From Penicillium oxalicum PJ3
Lee, Seung Ho, Cho, Jaiesoon, Bok, Jinduck, Kang, Seungha, Choi, Yunjaie and Lee, Peter C. W. (2014). Characterization, Gene Cloning, and Sequencing of a Fungal Phytase, PhyA, From Penicillium oxalicum PJ3. Preparative Biochemistry and Biotechnology, 45 (4), 336-347. doi: 10.1080/10826068.2014.923446
2013
Journal Article
Impact of ethnicity, geography, and disease on the microbiota in health and inflammatory bowel disease
Prideaux L., Kang S., Wagner J., Buckley M., Mahar J.E., De Cruz P., Wen Z., Chen L., Xia B., Van Langenberg D.R., Lockett T., Ng S.C., Sung J.J.Y., Desmond P., McSweeney C., Morrison M., Kirkwood C.D. and Kamm M.A. (2013). Impact of ethnicity, geography, and disease on the microbiota in health and inflammatory bowel disease. Inflammatory Bowel Diseases, 19 (13), 2906-2918. doi: 10.1097/01.MIB.0000435759.05577.12
Funding
Current funding
Supervision
Availability
- Dr Seungha Kang is:
- Available for supervision
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