Dr Brett Paterson
Dr

Brett Paterson

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Background

After completing my undergraduate and postgraduate studies at the University of Melbourne, I had a Postdoctoral position at the University of Melbourne from 2011-2013 and held a Victorian Postdoctoral Resarch Fellowship at Kings College London (UK) from 2014-2015 and University of Melbourne in 2016. I took up an Australian Research Council DECRA Fellowship at Monash University from 2017-2019 and was a National Imaging Facility research fellow from 2020-2021. I joined The University of Queensland in 2022 as the Head of Radiochemistry at the Centre for Advanced Imaging.

Availability

Dr Brett Paterson is:
Available for supervision

Research impacts

Design and synthesis of radiopharmaceuticals for molecular imaging and targeted radiotherapy. In collaboration with industry, Associate Prof Paterson's research has contributed to the development and translation of new agents for the detection and treatment of cancer.

Search Professor Brett Paterson’s works on UQ eSpace

84 works between 1974 and 2023
All (84) Journal Article (80) Book Chapter (1) Conference Publication (3)

21 - 40 of 84 works

2017

Journal Article

Frontispiece: Guest-induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes

Paterson, Brett M., White, Keith F., White, Jonathan M., Abrahams, Brendan F. and Donnelly, Paul S. (2017). Frontispiece: Guest-induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes. Angewandte Chemie International Edition, 56 (29). doi: 10.1002/anie.201782961

Frontispiece: Guest-induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes

2017

Journal Article

Guest‐induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes

Paterson, Brett M., White, Keith F., White, Jonathan M., Abrahams, Brendan F. and Donnelly, Paul S. (2017). Guest‐induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes. Angewandte Chemie, 129 (29), 8490-8494. doi: 10.1002/ange.201701596

Guest‐induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes

2017

Journal Article

Guest-induced assembly of bis(thiosemicarbazonato) zinc(II) coordination nanotubes

Paterson, Brett M., White, Keith F., White, Jonathan M., Abrahams, Brendan F. and Donnelly, Paul S. (2017). Guest-induced assembly of bis(thiosemicarbazonato) zinc(II) coordination nanotubes. Angewandte Chemie - International Edition, 56 (29), 8370-8374. doi: 10.1002/anie.201701596

Guest-induced assembly of bis(thiosemicarbazonato) zinc(II) coordination nanotubes

2016

Journal Article

Highly sensitive detection of minimal cardiac ischemia using positron emission tomography imaging of activated platelets

Ziegler, Melanie, Alt, Karen, Paterson, Brett M., Kanellakis, Peter, Bobik, Alex, Donnelly, Paul S., Hagemeyer, Christoph E. and Peter, Karlheinz (2016). Highly sensitive detection of minimal cardiac ischemia using positron emission tomography imaging of activated platelets. Scientific Reports, 6 (1) 38161. doi: 10.1038/srep38161

Highly sensitive detection of minimal cardiac ischemia using positron emission tomography imaging of activated platelets

2016

Conference Publication

First-Time-in-Human Trial of Cu-64 MeCOSAR-octreotate (CuSARTATE) for Imaging and Dosimetry Estimation in Neuroendocrine Tumor (NET)

Hicks, Rodney, Jackson, Price, Ware, Robert, Drummond, Elizabeth, Roselt, Peter, Noonan, Wayne, Price, Roger, Jeffrey, Charmaine, Callahan, Jason, Hong, Emily, Hicks, Lauren, Hedt, Amos, Paterson, Brett, Kong, Grace and Donnelly, Paul (2016). First-Time-in-Human Trial of Cu-64 MeCOSAR-octreotate (CuSARTATE) for Imaging and Dosimetry Estimation in Neuroendocrine Tumor (NET). RESTON: SOC NUCLEAR MEDICINE INC.

First-Time-in-Human Trial of Cu-64 MeCOSAR-octreotate (CuSARTATE) for Imaging and Dosimetry Estimation in Neuroendocrine Tumor (NET)

2016

Book Chapter

Macrocyclic bifunctional chelators and conjugation strategies for copper-64 radiopharmaceuticals

Paterson, Brett M. and Donnelly, Paul S. (2016). Macrocyclic bifunctional chelators and conjugation strategies for copper-64 radiopharmaceuticals. Insights from Imaging in Bioinorganic Chemistry. (pp. 223-251) edited by Rudi van Eldik and Colin D. Hubbard. San Diego, CA United States: Academic Press. doi: 10.1016/bs.adioch.2015.09.005

Macrocyclic bifunctional chelators and conjugation strategies for copper-64 radiopharmaceuticals

2015

Journal Article

Copper-64 Labeled Macrobicyclic Sarcophagine Coupled to a GRP Receptor Antagonist Shows Great Promise for PET Imaging of Prostate Cancer

Gourni, Eleni, Del Pozzo, Luigi, Kheirallah, Emilie, Smerling, Christiane, Waser, Beatrice, Reubi, Jean-Claude, Paterson, Brett M., Donnelly, Paul S., Meyer, Philipp T. and Maecke, Helmut R. (2015). Copper-64 Labeled Macrobicyclic Sarcophagine Coupled to a GRP Receptor Antagonist Shows Great Promise for PET Imaging of Prostate Cancer. Molecular Pharmaceutics, 12 (8), 2781-2790. doi: 10.1021/mp500671j

Copper-64 Labeled Macrobicyclic Sarcophagine Coupled to a GRP Receptor Antagonist Shows Great Promise for PET Imaging of Prostate Cancer

2015

Journal Article

A versatile approach for the site-specific modification of recombinant antibodies using a combination of enzyme-mediated bioconjugation and click chemistry

Alt, Karen, Paterson, Brett M., Westein, Erik, Rudd, Stacey E., Poniger, Stan S., Jagdale, Shweta, Ardipradja, Katie, Connell, Timothy U., Krippner, Guy Y., Nair, Ashish K. N., Wang, Xiaowei, Tochon-Danguy, Henri J., Donnelly, Paul S., Peter, Karlheinz and Hagemeyer, Christoph E. (2015). A versatile approach for the site-specific modification of recombinant antibodies using a combination of enzyme-mediated bioconjugation and click chemistry. Angewandte Chemie - International Edition, 54 (26), 7515-7519. doi: 10.1002/anie.201411507

A versatile approach for the site-specific modification of recombinant antibodies using a combination of enzyme-mediated bioconjugation and click chemistry

2015

Journal Article

The ionic charge of copper-64 complexes conjugated to an engineered antibody affects biodistribution

Dearling, Jason L. J., Paterson, Brett M., Akurathi, Vamsidhar, Betanzos-Lara, Soledad, Treves, S. Ted, Voss, Stephan D., White, Jonathan M., Huston, James S., Smith, Suzanne V., Donnelly, Paul S. and Packard, Alan B. (2015). The ionic charge of copper-64 complexes conjugated to an engineered antibody affects biodistribution. Bioconjugate Chemistry, 26 (4), 707-717. doi: 10.1021/acs.bioconjchem.5b00049

The ionic charge of copper-64 complexes conjugated to an engineered antibody affects biodistribution

2015

Journal Article

Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with 89Zr4+: Comparison with desferrioxamine-B

Ma, Michelle T., Meszaros, Levente K., Paterson, Brett M., Berry, David J., Cooper, Maggie S., Ma, Yongmin, Hider, Robert C. and Blower, Philip J. (2015). Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with 89Zr4+: Comparison with desferrioxamine-B. Dalton Transactions, 44 (11), 4884-4900. doi: 10.1039/c4dt02978j

Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with 89Zr4+: Comparison with desferrioxamine-B

2015

Journal Article

Engineering poly(ethylene glycol) particles for improved biodistribution

Cui, Jiwei, De Rose, Robert, Alt, Karen, Alcantara, Sheilajen, Paterson, Brett M., Liang, Kang, Hu, Ming, Richardson, Joseph J., Yan, Yan, Jeffery, Charmaine M., Price, Roger I., Peter, Karlheinz, Hagemeyer, Christoph E., Donnelly, Paul S., Kent, Stephen J. and Caruso, Frank (2015). Engineering poly(ethylene glycol) particles for improved biodistribution. ACS Nano, 9 (2), 1571-1580. doi: 10.1021/nn5061578

Engineering poly(ethylene glycol) particles for improved biodistribution

2015

Journal Article

Bifunctional 64Cu-labelled macrobicyclic cage amine isothiocyanates for immuno-positron emission tomography

Paterson, Brett M., Buncic, Gojko, McInnes, Lachlan E., Roselt, Peter, Cullinane, Carleen, Binns, David S., Jeffery, Charmaine M., Price, Roger I., Hicks, Rodney J. and Donnelly, Paul S. (2015). Bifunctional 64Cu-labelled macrobicyclic cage amine isothiocyanates for immuno-positron emission tomography. Dalton Transactions, 44 (11), 4901-4909. doi: 10.1039/c4dt02983f

Bifunctional 64Cu-labelled macrobicyclic cage amine isothiocyanates for immuno-positron emission tomography

2014

Journal Article

+ complexes of exo-functionalized tridentate "click" macrocycles: Synthesis, stability, photophysical properties, bioconjugation, and antibacterial activity

Noor, Asif, Huff, Gregory S., Kumar, Sreedhar V., Lewis, James E. M., Paterson, Brett M., Schieber, Christine, Donnelly, Paul S., Brooks, Heather J. L., Gordon, Keith C., Moratti, Stephen C. and Crowley, James D. (2014). + complexes of exo-functionalized tridentate "click" macrocycles: Synthesis, stability, photophysical properties, bioconjugation, and antibacterial activity. Organometallics, 33 (24), 7031-7043. doi: 10.1021/om500664v

+ complexes of exo-functionalized tridentate "click" macrocycles: Synthesis, stability, photophysical properties, bioconjugation, and antibacterial activity

2014

Journal Article

Single-Chain antibody conjugated to a cage amine chelator and labeled with positron-emitting copper-64 for diagnostic imaging of activated platelets

Alt, Karen, Paterson, Brett M., Ardipradja, Katie, Schieber, Christine, Buncic, Gojko, Lim, Bock, Poniger, Stan S., Jakoby, Bjoern, Wang, Xiaowei, Okeefe, Graeme J., Tochon-Danguy, Henri J., Scott, Andrew M., Ackermann, Uwe, Peter, Karlheinz, Donnelly, Paul S. and Hagemeyer, Christoph E. (2014). Single-Chain antibody conjugated to a cage amine chelator and labeled with positron-emitting copper-64 for diagnostic imaging of activated platelets. Molecular Pharmaceutics, 11 (8), 2855-2863. doi: 10.1021/mp500209a

Single-Chain antibody conjugated to a cage amine chelator and labeled with positron-emitting copper-64 for diagnostic imaging of activated platelets

2014

Journal Article

Enzyme-mediated site-specific bioconjugation of metal complexes to proteins: Sortase-mediated coupling of copper-64 to a single-chain antibody

Paterson, Brett M., Alt, Karen, Jeffery, Charmaine M., Price, Roger I., Jagdale, Shweta, Rigby, Sheena, Williams, Charlotte C., Peter, Karlheinz, Hagemeyer, Christoph E. and Donnelly, Paul S. (2014). Enzyme-mediated site-specific bioconjugation of metal complexes to proteins: Sortase-mediated coupling of copper-64 to a single-chain antibody. Angewandte Chemie - International Edition, 53 (24), 6115-6119. doi: 10.1002/anie.201402613

Enzyme-mediated site-specific bioconjugation of metal complexes to proteins: Sortase-mediated coupling of copper-64 to a single-chain antibody

2014

Journal Article

Neuroprotective copper bis(thiosemicarbazonato) complexes promote neurite elongation

Bica, Laura, Liddell, Jeffrey R., Donnelly, Paul S., Duncan, Clare, Caragounis, Aphrodite, Volitakis, Irene, Paterson, Brett M., Cappai, Roberto, Grubman, Alexandra, Camakaris, James, Crouch, Peter J. and White, Anthony R. (2014). Neuroprotective copper bis(thiosemicarbazonato) complexes promote neurite elongation. PLoS ONE, 9 (2) e90070, e90070. doi: 10.1371/journal.pone.0090070

Neuroprotective copper bis(thiosemicarbazonato) complexes promote neurite elongation

2014

Journal Article

PET imaging of tumours with a 64Cu labeled macrobicyclic cage amine ligand tethered to Tyr3-octreotate

Paterson, Brett M., Roselt, Peter, Denoyer, Delphine, Cullinane, Carleen, Binns, David, Noonan, Wayne, Jeffery, Charmaine M., Price, Roger I., White, Jonathan M., Hicks, Rodney J. and Donnelly, Paul S. (2014). PET imaging of tumours with a 64Cu labeled macrobicyclic cage amine ligand tethered to Tyr3-octreotate. Dalton Transactions, 43 (3), 1386-1396. doi: 10.1039/c3dt52647j

PET imaging of tumours with a 64Cu labeled macrobicyclic cage amine ligand tethered to Tyr3-octreotate

2014

Journal Article

Antimicrobial effects of copper(II) bis(thiosemicarbazonato) complexes provide new insight into their biochemical mode of action

Djoko, Karrera Y., Paterson, Brett M., Donnelly, Paul S. and McEwan, Alastair G. (2014). Antimicrobial effects of copper(II) bis(thiosemicarbazonato) complexes provide new insight into their biochemical mode of action. Metallomics, Advance Article (4), 1-10. doi: 10.1039/C3MT00348E

Antimicrobial effects of copper(II) bis(thiosemicarbazonato) complexes provide new insight into their biochemical mode of action

2014

Journal Article

Oral treatment with CuII(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis

Roberts, Blaine R., Lim, Nastasia K. H., McAllum, Erin J., Donnelly, Paul S., Hare, Dominic J., Doble, Philip A., Turner, Bradley J., Price, Katherine A., Lim, Sin Chun, Paterson, Brett M., Hickey, James L., Rhoads, Timothy W., Williams, Jared R., Kanninen, Katja M., Hung, Lin W., Liddell, Jeffrey R., Grubman, Alexandra, Monty, Jean-Francois, Llanos, Roxana M., Kramer, David R., Mercer, Julian F. B., Bush, Ashley I., Masters, Colin L., Duce, James A., Li, Qiao-Xin, Beckman, Joseph S., Barnham, Kevin J., White, Anthony R. and Crouch, Peter J. (2014). Oral treatment with CuII(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis. Journal of Neuroscience, 34 (23), 8021-8031. doi: 10.1523/JNEUROSCI.4196-13.2014

Oral treatment with CuII(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis

2013

Journal Article

Therapeutic effects of CuII(atsm) in the SOD1-G37R mouse model of amyotrophic lateral sclerosis

McAllum, Erin J., Lim, Nastasia K.-H., Hickey, James L., Paterson, Brett M., Donnelly, Paul S., Li, Qiao-Xin, Liddell, Jeffrey R., Barnham, Kevin J., White, Anthony R. and Crouch, Peter J. (2013). Therapeutic effects of CuII(atsm) in the SOD1-G37R mouse model of amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 14 (7-8), 586-590. doi: 10.3109/21678421.2013.824000

Therapeutic effects of CuII(atsm) in the SOD1-G37R mouse model of amyotrophic lateral sclerosis

Current funding

  • 2024 - 2027
    Understanding production and application of alpha emitting radionuclides
    ARC Linkage Projects
    Open grant
  • 2023 - 2028
    ARC Research Hub for Advanced Manufacture of Targeted Radiopharmaceuticals
    ARC Industrial Transformation Research Hubs
    Open grant
  • 2017 - 2024
    ARC Training Centre for Innovation in Biomedical Imaging Technology
    ARC Industrial Transformation Training Centres
    Open grant

Availability

Dr Brett Paterson is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Enquiries

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