
Overview
Background
Associate Professor Paul Dawson is the Mater Research Head of Education, MRI-UQ Director of Higher Degree Research, and a Mater Foundation Principal Research Fellow. Paul leads the Neurodevelopmental Research Group at Mater, which is focussed on cerebral palsy in preterm infants, non-syndromic intellectual disability and autism.
Paul’s research group collaborates very closely with neonatologists, maternal fetal medicine specialists, obstetricians, bioinformaticians and biochemical pathologists at Mater to investigate clinical, biochemical and genetic markers that predict adverse neurodevelopmental outcomes. In particular, his research is focussed on the role of nutrient sulphate in brain development. Paul through his work has brought many collaborative groups together. Some of his notable collaborations are with the Queensland Brain Institute (QBI), Royal Brisbane and Women’s Hospital (RBWH), UQ Centre for Clinical Research (UQCCR), the University of Sydney and the Cerebral Palsy Alliance.
With over 80 research publications, Paul notes a career highlight as being one of the key investigators, and Autism Biobank member, in the Autism Cooperative Research Centre (CRC) which was awarded $31 million from the Australian government.
Paul is heavily involved in national and international peer review and is a strong advocate for health and medical research with executive roles (Past-President 2012, Chair Advisory Committee) for the Australian Society for Medical Research (ASMR).
‘My career in medical research happened for many reasons, including my interest and passion for understanding the genetics of disorders that impact on people’s health and well-being. In my early days, I was fortunate to work with a group of like-minded biomedical and clinician scientists which kicked off many discoveries in neurodevelopment, as well as the opportunity to develop and investigate pre-clinical models with the aim of implementing research outcomes to improve healthcare. Working at Mater provides a fantastic opportunity to investigate new approaches for reducing the risk of adverse neurodevelopmental outcomes in preterm infants. I look forward to the coming years when the benefits of our Mater-led research will be realised and proven around the globe. It’s a privilege to contribute to Australian health and medical research.’
Availability
- Dr Paul Dawson is:
- Available for supervision
Fields of research
Qualifications
- Bachelor (Honours) of Science (Advanced), University of New England Australia
- Doctor of Philosophy, The University of Queensland
Research impacts
Since joining Mater Research in 2010, A/Prof Dawson has brought together collaborative groups of clinicians, biomedical researchers, research entities (MCH/LCCH, MMH, QBI, QCIDD, AIBN, UQ CAI and SBMS) and the Mater Foundation, to investigate the aetiology of neurodevelopmental disorders. These collaborations align with Mater’s strategic research programs Neuroscience and Cognitive Health and Mothers, Babies and Maternal Care. A/Prof Dawson was appointed Program Leader of Neurosciences and Cognitive Health in June 2016. Highlights of A/Prof Dawson’s research achievements include:
- Investigator (and Autism Biobank member representing Mater Research) in Program 1 of Autism CRC ($31.01M) 2013-2020.
- Investigator in the Queensland Floods 2011 (QF2011) study, studying the consequences of prenatal maternal stress on child behavioural, developmental and metabolic outcomes. Co-author on 2 publications.
- CIA on NHMRC-funded study ($720k 2015-2019, ranked 3rd quartile category 6) to investigate the links between biochemistry, genetics and neurodevelopmental outcomes, including cerebral palsy, in preterm infants.
- Principal Investigator on an Autism CRC Innovative grant using iPS cells as a model to study the cellular and molecular basis of autism ($40k, 2014-2015).
- Investigator on genetic/clinical studies of Intellectual Disability, with collaborations between Mater Research, LCCH, QCIDD and the Queensland Brain Institute.
- Initiated and led a world-first NATA approved diagnostic test (and establishment of clinical reference ranges) for plasma and urine sulphate measurements in Mater Pathology, South Brisbane, which has gained media attention for use in his NHMRC-funded neurodevelopmental studies.
- His achievements in perinatal research were recognised with the 2016 Simon & Nell George Award ($10,000) in recognition of exceptional work undertaken at the Mater in the area of Maternal and/or early childhood health and for support for the work of the Mater Foundation.
- Oral presentations at 25 local and 20 national/international scientific meetings.
- Initiated and prepared grant applications with successful funding of $1.5M (2010-present).
- Contributed as investigator on equipment grants with funding of $540,000 (2011-present).
- Recipient of Mater Foundation Research Fellowship (2014-20).
Works
Search Professor Paul Dawson’s works on UQ eSpace
2004
Journal Article
Therapeutic potential of hammerhead ribozymes in the treatment of hyper-proliferative diseases
Grassi, G., Dawson, P., Guarnieri, G., Kandolf, R. and Grassi, M. (2004). Therapeutic potential of hammerhead ribozymes in the treatment of hyper-proliferative diseases. Current Pharmaceutical Biotechnology, 5 (4), 369-386. doi: 10.2174/1389201043376760
2003
Journal Article
D and z-values for Listeria monocytogenes and Salmonella typhimurium in packaged low-fat ready-to-eat turkey bologna subjected to a surface pasteurization treatment
McCormick, K., Han, I., Acton, J., Sheldon, B. and Dawson, P. (2003). D and z-values for Listeria monocytogenes and Salmonella typhimurium in packaged low-fat ready-to-eat turkey bologna subjected to a surface pasteurization treatment. Poultry Science, 82 (8), 1337-1342. doi: 10.1093/ps/82.8.1337
2003
Book Chapter
Nisin in the decontamination of animal products
Dawson, P. L. and Sheldon, B. W. (2003). Nisin in the decontamination of animal products. Natural Antimicrobials for the Minimal Processing of Foods. (pp. 34-63) Elsevier Ltd. doi: 10.1016/B978-1-85573-669-6.50008-3
2003
Journal Article
Effects of Antioxidants in Polyethylene Film on Fresh Beef Color
Moore, M.E., Han, I.Y., Acton, J.C., Ogale, A.A., Barmore, C. R. and Dawson, P.L. (2003). Effects of Antioxidants in Polyethylene Film on Fresh Beef Color. Journal of Food Science, 68 (1), 99-104. doi: 10.1111/j.1365-2621.2003.tb14122.x
2003
Journal Article
Hyposulfatemia, growth retardation, reduced fertility, and seizures in mice lacking a functional NaSi-1 gene
Dawson, P. A., Beck, L. and Markovich, D. (2003). Hyposulfatemia, growth retardation, reduced fertility, and seizures in mice lacking a functional NaSi-1 gene. Proceedings of the National Academy of Sciences, 100 (23), 13704-13709. doi: 10.1073/pnas.2231298100
2003
Journal Article
Nisin release from films is affected by both protein type and film-forming method
Dawson, P. L., Hirt, D. E., Rieck, J. R., Acton, J. C. and Sotthibandhu, A. (2003). Nisin release from films is affected by both protein type and film-forming method. Food Research International, 36 (9-10), 959-968. doi: 10.1016/S0963-9969(03)00116-9
2002
Journal Article
Nisin Diffusion in Protein Films: Effects of Film Type and Temperature
Teerakarn, A., Hirt, D.E., Acton, J.C., Rieck, J.R. and Dawson, P.L. (2002). Nisin Diffusion in Protein Films: Effects of Film Type and Temperature. Journal of Food Science, 67 (8), 3019-3025. doi: 10.1111/j.1365-2621.2002.tb08853.x
2002
Journal Article
Regulation of the mouse Nas1 promoter by vitamin D and thyroid hormone
Dawson, P. A. and Markovich, D. (2002). Regulation of the mouse Nas1 promoter by vitamin D and thyroid hormone. European Journal of Physiology, 444 (3), 353-359. doi: 10.1007/s00424-002-0789-x
2002
Journal Article
Effect of lauric acid and nisin-impregnated soy-based films on the growth of Listeria monocytogenes on turkey bologna
Dawson, P., Carl, G., Acton, J. and Han, I. (2002). Effect of lauric acid and nisin-impregnated soy-based films on the growth of Listeria monocytogenes on turkey bologna. Poultry Science, 81 (5), 721-726. doi: 10.1093/ps/81.5.721
2002
Journal Article
Transcriptional regulation of the sodium-sulfate cotransporter NaSi-1 gene
Dawson, P. A. and Markovich, D. (2002). Transcriptional regulation of the sodium-sulfate cotransporter NaSi-1 gene. Cell Biochemistry And Biophysics, 36 (2-3), 175-182. doi: 10.1385/CBB:36:2-3:175
2002
Journal Article
Soy protein isolate/corn-zein laminated films: Transport and mechanical properties
Pol, H., Dawson, P., Acton, J. and Ogale, A. (2002). Soy protein isolate/corn-zein laminated films: Transport and mechanical properties. Journal of Food Science, 67 (1), 212-217. doi: 10.1111/j.1365-2621.2002.tb11386.x
2002
Journal Article
Antioxidative effect of Maillard reaction products added to turkey meat during heating by addition of honey
Antony, S. M., Han, I. Y., Rieck, J. R. and Dawson, P. L. (2002). Antioxidative effect of Maillard reaction products added to turkey meat during heating by addition of honey. Journal of Food Science, 67 (5), 1719-1724. doi: 10.1111/j.1365-2621.2002.tb08712.x
2001
Journal Article
Antimicrobial effects of corn zein films impregnated with nisin, lauric acid, and EDTA
Hoffman, K. L., Han, I. Y. and Dawson, P. L. (2001). Antimicrobial effects of corn zein films impregnated with nisin, lauric acid, and EDTA. Journal of Food Protection, 64 (6), 885-889. doi: 10.4315/0362-028X-64.6.885
2001
Journal Article
The effect of shell egg pasteurization on the protein quality of albumen
Hank, C. R., Kunkel, M. E., Dawson, P. L., Acton, J. C. and Wardlaw Jr., F. B. (2001). The effect of shell egg pasteurization on the protein quality of albumen. Poultry Science, 80 (6), 821-824. doi: 10.1093/ps/80.6.821
2000
Journal Article
Antioxidative effect of Maillard reaction products formed from honey at different reaction times
Antony, S. M., Han, I. Y., Rieck, J. R. and Dawson, P. L. (2000). Antioxidative effect of Maillard reaction products formed from honey at different reaction times. Journal of Agricultural and Food Chemistry, 48 (9), 3985-3989. doi: 10.1021/jf000305x
2000
Journal Article
Hammerhead ribozymes selectively suppress mutant type I collagen mRNA in osteogenesis imperfecta fibroblasts
Dawson, Paul A. and Marini, Joan C. (2000). Hammerhead ribozymes selectively suppress mutant type I collagen mRNA in osteogenesis imperfecta fibroblasts. Nucleic Acids Research, 28 (20), 4013-4020. doi: 10.1093/nar/28.20.4013
2000
Journal Article
Effect of lauric acid addition on the antimicrobial efficacy and water permeability of corn zein films containing nisin
Padgett, T., Han, I. Y. and Dawson, P. L. (2000). Effect of lauric acid addition on the antimicrobial efficacy and water permeability of corn zein films containing nisin. Journal of Food Processing and Preservation, 24 (5), 423-432. doi: 10.1111/j.1745-4549.2000.tb00429.x
2000
Journal Article
Effect of dry honey on oxidation in Turkey breast meat
Antony, S., Rieck, J. R. and Dawson, P. L. (2000). Effect of dry honey on oxidation in Turkey breast meat. Poultry Science, 79 (12), 1846-1850. doi: 10.1093/ps/79.12.1846
2000
Conference Publication
Development of a mutation suppression approach to the gene therapy of osteogenesis imperfecta
Forlino, A., Dawson, P. A., Lisi, and Marini, J. C. (2000). Development of a mutation suppression approach to the gene therapy of osteogenesis imperfecta. Unknown, Unknown, Unknown. New York, NY United States: Nature Publishing Group.
2000
Book Chapter
Packaging
Dawson, Paul L. (2000). Packaging. Poultry Meat Processing. (pp. 73-95) CRC Press.
Funding
Current funding
Supervision
Availability
- Dr Paul Dawson is:
- Available for supervision
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Available projects
-
Neuroprotective role of sulfate in preterm infants
PhD project to investigate the molecular genetics and pathophysiology of nutrient sulfate deficiency in human fetal and neonatal development. The project will incorporate clinical, biochemical, genetic and molecular biology approaches.
-
Investigation of individuals with idiopathic intellectual disability
This study will investigate the genetic causes/factors that may contribute to currently unexplained intellectual disability. The study will increase understanding of fundamental biological abnormalities underpinning intellectual disability.
Supervision history
Current supervision
-
Doctor Philosophy
Neuroprotective role of sulphate among preterm infants (SuPreme study)
Principal Advisor
-
Doctor Philosophy
Molecular analyses of sulfation pathways in neurodevelopment following preterm birth
Principal Advisor
Other advisors: Dr Yvonne Eiby
-
Doctor Philosophy
Neuroprotective role of sulphate among preterm infants (SuPreme study)
Principal Advisor
-
Doctor Philosophy
Characterisation of sulfate deficiency on preterm neonatal bone growth and development.
Principal Advisor
Other advisors: Professor Allison Pettit, Dr Yvonne Eiby, Dr Susan Millard
-
Master Philosophy
The right ventricular (RV) response to exercise in patients with established pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH) and correlation to prognostic markers
Associate Advisor
Completed supervision
-
2008
Doctor Philosophy
Physiological analysis of xenobiotic toxicity, steroids and neurotransmitters in mouse models of hyposulfataemia
Principal Advisor
-
2015
Doctor Philosophy
Investigating the role of the placental sulfate transporter Slc13a4 in fetal development.
Joint Principal Advisor
Other advisors: Dr David Simmons
-
2023
Doctor Philosophy
Genetic variants in Angelman syndrome and related disorders: relationship to phenotype and neuronal function
Associate Advisor
Other advisors: Associate Professor Honey Heussler
-
2018
Doctor Philosophy
Role of the Sulfate Transporter SLC13A4 in Brain Development and Function
Associate Advisor
Other advisors: Dr David Simmons
Media
Enquiries
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