Overview
Availability
- Dr Yvonne Eiby is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Science, The University of Queensland
- Bachelor (Honours) of Science (Advanced), The University of Queensland
- Doctor of Philosophy, The University of Queensland
Research interests
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Neonatal physiology
Improving brain outcomes for preterm infants by developing effective cardiovascular and nutritional support in early life.
Works
Search Professor Yvonne Eiby’s works on UQ eSpace
Featured
2023
Journal Article
Red cell infusion but not saline is effective for volume expansion in preterm piglets
Eiby, Yvonne A., Wright, Ian M. R., Stark, Michael J. and Lingwood, Barbara E. (2023). Red cell infusion but not saline is effective for volume expansion in preterm piglets. Pediatric Research, 94 (1), 112-118. doi: 10.1038/s41390-022-02403-2
2018
Journal Article
Reduced blood volume decreases cerebral blood flow in preterm piglets
Eiby, Yvonne A., Shrimpton, Nicole Y., Wright, Ian M. R., Lumbers, Eugenie R., Colditz, Paul B., Duncombe, Greg J. and Lingwood, Barbara E. (2018). Reduced blood volume decreases cerebral blood flow in preterm piglets. The Journal of Physiology, 596 (23), 6033-6041. doi: 10.1113/JP275583
2018
Conference Publication
Preterm piglets are a model of human preterm infant sulphate deficiency
Dawson, P. A., Eiby, Y. A., Barnes, S. K., Boyd, R. N., Badawi, N., Koorts, P. J., Kumar, S., Flenady, V. J., Hurrion, E. M, Colditz, P. B. and Lingwood, B. E. (2018). Preterm piglets are a model of human preterm infant sulphate deficiency. 22nd Annual Congress of the Perinatal Society of Australia and New Zealand (PSANZ), Auckland, New Zealand, 25–28 March 2018. Chichester, West Sussex United Kingdom: Wiley. doi: 10.1111/jpc.13882_186
2016
Journal Article
Inotropes do not increase cardiac output or cerebral blood flow in preterm piglets
Eiby, Yvonne A., Shrimpton, Nicole Y. , Wright, Ian M. R. , Lumbers, Eugenie R., Colditz, Paul B. , Duncombe, Greg J. and Lingwood, Barbara E. (2016). Inotropes do not increase cardiac output or cerebral blood flow in preterm piglets. Pediatric Research, 80 (6), 870-879. doi: 10.1038/pr.2016.156
2013
Journal Article
A Pig Model of the Preterm Neonate: Anthropometric and Physiological Characteristics
Eiby, Yvonne A., Wright, Layne L., Kalanjati, Viskasari P., Miller, Stephanie M., Bjorkman, Stella T., Keates, Helen L., Lumbers, Eugenie R., Colditz, Paul B. and Lingwood, Barbara E. (2013). A Pig Model of the Preterm Neonate: Anthropometric and Physiological Characteristics. PLoS ONE, 8 (7) e68763, e68763. doi: 10.1371/journal.pone.0068763
2024
Journal Article
Blood volume reduction due to rapid plasma loss after birth in preterm piglets
Nguyen, Tam M. T., Morwood, Holly, Bakrania, Bhavisha A., Miller, Stephanie M., Bjorkman, Stella T., Lingwood, Barbara E., Wright, Ian M. R. and Eiby, Yvonne A. (2024). Blood volume reduction due to rapid plasma loss after birth in preterm piglets. Pediatric Research. doi: 10.1038/s41390-024-03252-x
2024
Conference Publication
Is NIRS Useful for Monitoring Cerebral Oxygen Delivery in Preterm Newborns? (P11-8.006)
Ashley, Daniel and Eiby, Yvonne (2024). Is NIRS Useful for Monitoring Cerebral Oxygen Delivery in Preterm Newborns? (P11-8.006). 2024 American Academy of Neurology Annual Meeting, Denver, CO United States, 13-18 April 2024. Philadelphia, PA United States: Wolters Kluwer. doi: 10.1212/wnl.0000000000204790
2024
Journal Article
Modified turbidometric microassay for the measurement of sulfate in plasma and urine
Vijayakumar, Prasidhee, McWhinney, Avis, Eiby, Yvonne and Dawson, Paul (2024). Modified turbidometric microassay for the measurement of sulfate in plasma and urine. MethodsX, 12 102712, 102712. doi: 10.1016/j.mex.2024.102712
2022
Other Outputs
Measuring blood volume in preterm piglets
Morwood, Holly, Bakrania, Bhavisha A., Wright, Ian M. R., Eiby, Yvonne A. and Lingwood, Barbara E. (2022). Measuring blood volume in preterm piglets. The University of Queensland. (Dataset) doi: 10.48610/65b722d
2022
Journal Article
Expression of TRPM6 and TRPM7 in the preterm piglet heart
Forbes, Elizabeth M., Bakrania, Bhavisha A., Steane, Sarah E., Moritz, Karen M., Lingwood, Barbara E. and Eiby, Yvonne A. (2022). Expression of TRPM6 and TRPM7 in the preterm piglet heart. Frontiers in Pediatrics, 10 891722, 1-11. doi: 10.3389/fped.2022.891722
2022
Other Outputs
Cardiac TRPM6 and 7 piglets
Forbes, Elizabeth, Bakrania, Bhavisha, Steans, Sarah, Moritz, Karen, Lingwood, Barbara and Eiby, Yvonne (2022). Cardiac TRPM6 and 7 piglets. The University of Queensland. (Dataset) doi: 10.48610/0dac82b
2021
Journal Article
Plasma leak from the circulation contributes to poor outcomes for preterm infants: a working hypothesis
Eiby, Yvonne A., Lingwood, Barbara E. and Wright, Ian M. R. (2021). Plasma leak from the circulation contributes to poor outcomes for preterm infants: a working hypothesis. Frontiers in Neurology, 12 636740, 1-9. doi: 10.3389/fneur.2021.636740
2020
Journal Article
Body composition in very preterm infants before discharge is associated with macronutrient intake
Lingwood, Barbara E., Al-Theyab, Nada, Eiby, Yvonne A., Colditz, Paul B. and Donovan, Tim J. (2020). Body composition in very preterm infants before discharge is associated with macronutrient intake. British Journal of Nutrition, 123 (7), 1-19. doi: 10.1017/S000711451900343X
2019
Journal Article
Supporting preterm cardiovascular function
Lingwood, Barbara E., Eiby, Yvonne A., Bjorkman, S. Tracey, Miller, Stephanie M. and Wright, Ian M. R. (2019). Supporting preterm cardiovascular function. Clinical and Experimental Pharmacology and Physiology, 46 (3), 274-279. doi: 10.1111/1440-1681.13044
2019
Journal Article
Fat trajectory after birth in very preterm infants mimics healthy term infants
Al-Theyab, N. A., Donovan, T. J., Eiby, Y. A., Colditz, P. B. and Lingwood, B. E. (2019). Fat trajectory after birth in very preterm infants mimics healthy term infants. Pediatric Obesity, 14 (3) e12472, e12472. doi: 10.1111/ijpo.12472
2017
Journal Article
Structure, organization and tissue expression of the pig SLC13A1 and SLC13A4 sulfate transporter genes
Barnes, Samuel K., Eiby, Yvonne A., Lee, Soohyun, Lingwood, Barbara E. and Dawson, Paul A (2017). Structure, organization and tissue expression of the pig SLC13A1 and SLC13A4 sulfate transporter genes. Biochemistry and Biophysics Reports, 10, 215-223. doi: 10.1016/j.bbrep.2017.04.005
2017
Journal Article
Review: Is rapid fat accumulation in early life associated with adverse later health outcomes?
Ratnasingham, Abirami, Eiby, Yvonne A., Dekker Nitert, Marloes, Donovan, Timothy and Lingwood, Barbara E. (2017). Review: Is rapid fat accumulation in early life associated with adverse later health outcomes?. Placenta, 54, 125-130. doi: 10.1016/j.placenta.2017.01.101
2017
Conference Publication
Plasma sulphate levels decline in the neonatal preterm piglet
Dawson, Paul, Lingwood, Barbara, Eiby, Yvonne, Barnes, Samuel, Colditz, Paul, Boyd, Roslyn, Badawi, Nadia, Koorts, Pieter, Kumar, Sailesh, Flenady, Vicki and Hurrion, Elizabeth (2017). Plasma sulphate levels decline in the neonatal preterm piglet. 21st Annual Congress of the Perinatal Society of Australia and New Zealand (PSANZ), Canberra, Australia, 2–5 April, 2017. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jpc.13494_68
2016
Conference Publication
Pilot trial of early blood transfusions for supporting cardiovascular function and cerebral oxygen delivery in preterm piglets
Eiby, Yvonne, Bjorkman, Tracey, Wixey, Julie, Chand, Kirat, Colditz, Paul and Lingwood, Barbara (2016). Pilot trial of early blood transfusions for supporting cardiovascular function and cerebral oxygen delivery in preterm piglets. 30th Annual meeting Fetal and Neonatal Workshop of Australia and New Zealand, Magnetic Island, QLD, Australia, 19-21 May 2016.
2015
Journal Article
Expression of genes of the cardiac and renal renin-angiotensin systems in preterm piglets: is this system a suitable target for therapeutic intervention?
Kim, Eleanor, Eiby, Yvonne, Lumbers, Eugenie, Boyce, Amanda, Gibson, Karen and Lingwood, Barbara (2015). Expression of genes of the cardiac and renal renin-angiotensin systems in preterm piglets: is this system a suitable target for therapeutic intervention?. Therapeutic Advances in Cardiovascular Disease, 9 (5), 285-296. doi: 10.1177/1753944715578615
Funding
Current funding
Supervision
Availability
- Dr Yvonne Eiby is:
- Available for supervision
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Available projects
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Early tranfusion to prevent hypovolemia in preterm newborns
PhD Scholarship
The Perinatal Research Centre at The University of Queensland, Australia, is currently seeking a PhD candidate for an NHMRC funded research project testing early transfusion in preterm neonates. The successful candidate will be located at the UQ Centre for Clinical Research on the Royal Brisbane and Womens’ Hospital campus at Herston, Brisbane. A UQ funded Scholarship is available and more information regarding eligibility, stipend, and how to apply can be found at:
https://scholarships.uq.edu.au/scholarship/earmarked-scholarships-support-category-1-project-grants
Project description
There are currently no clinical interventions that effectively prevent cardiovascular deterioration in premature babies. This project will use an established pre-clinical model to test the efficacy and safety of early transfusion for preventing hypovolemia and maintaining oxygen supply to the brain. Studying the cardiovascular and lymphatic physiology of preterm neonates using a large animal pre-clinical model is essential to the rational design of effective interventions to manage blood volume. This is a fully funded project.
The Team
This multidisciplinary team, led by Dr Yvonne Eiby, is comprised of neonatologists, vets and scientists. Our research improves the clinical care of preterm infants in order to protect the developing brain.
Pre-clinical model
The PhD candidate will gain hands on experience in our pre-clinical tertiary level neonatal intensive care unit and be trained in intensive care techniques such as intubation, ventilation and catheterization. Previous work with animals in not necessary. The candidate will also be trained in laboratory techniques as required by the project.
For further information contact: Yvonne Eiby (y.eiby@uq.edu.au)
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Lymphatic function in preterm piglets
There is very little known about the lymphatic function of premature babies. We have shown in our preterm piglet model that there are substantial reductions in lymphatic flow over the first day of life. This project will investigate how clinical management strategies influence flow rates with a view to develop novel interventions to reduce the high rates of disability in this vulnerable population.
Supervision history
Current supervision
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Doctor Philosophy
Factors driving blood volume loss in preterm piglets
Principal Advisor
Other advisors: Dr Bhavisha Bakrania
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Doctor Philosophy
Factors driving early plasma loss in preterm piglets
Principal Advisor
Other advisors: Dr Bhavisha Bakrania
-
Doctor Philosophy
Capillary ultrastructure and fluid loss from the circulation in preterm piglets
Principal Advisor
-
Doctor Philosophy
Characterisation of sulfate deficiency on preterm neonatal bone growth and development.
Associate Advisor
Other advisors: Professor Allison Pettit, Dr Susan Millard, Dr Paul Dawson
-
Doctor Philosophy
Molecular analyses of sulfation pathways in neurodevelopment following preterm birth
Associate Advisor
Other advisors: Dr Paul Dawson
Completed supervision
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2020
Master Philosophy
Changes in cardiac TRPM6 and TRPM7 expression during late gestation and transition to extra-uterine life in preterm and term piglets
Principal Advisor
Other advisors: Professor Karen Moritz
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2020
Doctor Philosophy
Infant body composition as a predictor of childhood obesity, cardiovascular risk and inflammatory markers
Associate Advisor
Other advisors: Associate Professor Marloes Nitert Dekker
Media
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