
Overview
Background
Dr Fernando's current research interests include developing needle-free, pain-free, skin patch vaccines. Influenza and human papilloma virus vaccines are used as model vaccines in these studies.
Dr Germain Fernando completed PhD at the University of Arizona, USA, and did post-doctoral research at the Baylor College of Medicine, Houston, Texas, USA, before joining the University of Queensland in 1989. He has been working in the field of vaccinology for the last 28 years. He has a H-Index of 36.
He is a Senior Consultant at Vaxxas Pty. Ltd, Brisbane, Australia
Publications and Citation Metrics are available at the following website:
http://www.researcherid.com/rid/C-3733-2009
Availability
- Dr Germain Fernando is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor (Honours) of Science (Advanced), Institution to be confirmed
- Doctor of Philosophy, Arizona State University
Research interests
-
Vaccinations using a novel needle-free, pain-free, skin patch.
Although effective vaccines are available for combating diseases such as flu and cervical cancer, some people are reluctant to get vaccinated because of the fear of the needle. The needle and syringe first invented in 1853 is still being used because of the convenience to the person administering the vaccine. However this method has many disadvantages: Fear of the needle and the pain of injection, especially among children. Furthermore injection into muscle is less efficient than delivering the vaccine directly to immunologically active cells in the skin. We have designed a skin patch to overcome these disadvantages. We have recently published data to show potent immunity can be induced using very low doses of vaccine delivered by the skin patch. Reference: Fernando et al PLoS One 2010 April 21:5(4), e 10266.
Works
Search Professor Germain Fernando’s works on UQ eSpace
1992
Journal Article
The vaccinia virus K2L gene encodes a serine protease inhibitor which inhibits cell-cell fusion
Zhou, J., Sun, X. Y., Fernando, G. J. P. and Frazer, I. H. (1992). The vaccinia virus K2L gene encodes a serine protease inhibitor which inhibits cell-cell fusion. Virology, 189 (2), 678-686. doi: 10.1016/0042-6822(92)90591-C
1992
Journal Article
Apolipoprotein-E - Phospholipid Binding-Studies with Synthetic Peptides From the Carboxyl Terminus
Sparrow, JT, Sparrow, DA, Fernando, G, Culwell, AR, Kovar, M and Gotto, AM (1992). Apolipoprotein-E - Phospholipid Binding-Studies with Synthetic Peptides From the Carboxyl Terminus. Biochemistry, 31 (4), 1065-1068. doi: 10.1021/bi00119a015
1991
Journal Article
A 'public' T-helper epitope of the E7 transforming protein of human papillomavirus 16 provides cognate help for several E7 B-cell epitopes from cervical cancer-associated human papillomavirus genotypes
Tindle, Robert W., Fernando, Germain J. P., Sterling, Jane C. and Frazer, Ian H. (1991). A 'public' T-helper epitope of the E7 transforming protein of human papillomavirus 16 provides cognate help for several E7 B-cell epitopes from cervical cancer-associated human papillomavirus genotypes. Proceedings of the National Academy of Sciences of the United States of America, 88 (13), 5887-5891. doi: 10.1073/pnas.88.13.5887
1988
Journal Article
Isolation and Characterization of Lipophorin From Drosophila-Melanogaster Larvae
Fernandowarnakulasuriya, Gjp and Wells, MA (1988). Isolation and Characterization of Lipophorin From Drosophila-Melanogaster Larvae. Archives of Insect Biochemistry and Physiology, 8 (4), 243-248. doi: 10.1002/arch.940080405
1988
Journal Article
Effect of Dietary-Lipid Content On Lipid Transport and Storage During Larval Development of Manduca-Sexta
Fernandowarnakulasuriya, Gjp, Tsuchida, K and Wells, MA (1988). Effect of Dietary-Lipid Content On Lipid Transport and Storage During Larval Development of Manduca-Sexta. Insect Biochemistry, 18 (2), 211-214. doi: 10.1016/0020-1790(88)90025-X
1987
Journal Article
Primary structure and comparative sequence-analysis of an insect apolipoprotein: apolipophorin-Iii from Manduca-sexta
Cole, Kenneth D., Fernando-Warnakulasuriya, Germain J. P., Boguski, Mark S., Freeman, Mark, Gordon, Jeffrey I., Clark, Wallace A., Law, John H. and Wells, Michael A. (1987). Primary structure and comparative sequence-analysis of an insect apolipoprotein: apolipophorin-Iii from Manduca-sexta. Journal of Biological Chemistry, 262 (24), 11794-11800.
1986
Journal Article
Lipoprotein biosynthesis in the larvae of the tobacco hornworm, Manduca-sexta
Prasad, Sarvamangala V., Fernando-Warnakulasuriya, Germain J. P., Sumida, Motoyuki, Law, John H. and Wells, Michael A. (1986). Lipoprotein biosynthesis in the larvae of the tobacco hornworm, Manduca-sexta. Journal of Biological Chemistry, 261 (36), 7174-7176.
1986
Journal Article
Lipoprotein biosynthesis in the larvae of the tobacco hornworm, Manduca sexta
Prasad, S. V., Fernando-Warnakulasuriya, G. J. P., Sumida, M., Law, J. H. and Wells, M. A. (1986). Lipoprotein biosynthesis in the larvae of the tobacco hornworm, Manduca sexta. Journal of Biological Chemistry, 261 (36), 17174-17176. doi: 10.1016/S0021-9258(19)76015-3
1986
Conference Publication
Amino-Acid-Sequence of Insect Apolipophorin-III
Fernandowarnakulasuriya, Gjp, Law, JH and Wells, MA (1986). Amino-Acid-Sequence of Insect Apolipophorin-III. NEW YORK: WILEY-LISS.
1984
Journal Article
Suberin-Grown Fusarium-Solani F-Sp Pisi Generates a Cutinase-Like Esterase Which Depolymerizes the Aliphatic Components of Suberin
Fernando, G, Zimmermann, W and Kolattukudy, PE (1984). Suberin-Grown Fusarium-Solani F-Sp Pisi Generates a Cutinase-Like Esterase Which Depolymerizes the Aliphatic Components of Suberin. Physiological Plant Pathology, 24 (2), 143-155. doi: 10.1016/0048-4059(84)90022-5
1983
Journal Article
Lipoprotein Metabolism in the Suckling Rat - Characterization of Plasma and Lymphatic Lipoproteins
Fernandowarnakulasuriya, Gjp, Eckerson, ML, Clark, WA and Wells, MA (1983). Lipoprotein Metabolism in the Suckling Rat - Characterization of Plasma and Lymphatic Lipoproteins. Journal of Lipid Research, 24 (12), 1626-1638.
1981
Journal Article
Studies On Fat Digestion, Absorption, and Transport in the Suckling Rat .2. Triacylglycerols - Molecular-Species, Stereospecific Analysis, and Specificity of Hydrolysis by Lingual Lipase
Staggers, JE, Fernandowarnakulasuriya, Gjp and Wells, MA (1981). Studies On Fat Digestion, Absorption, and Transport in the Suckling Rat .2. Triacylglycerols - Molecular-Species, Stereospecific Analysis, and Specificity of Hydrolysis by Lingual Lipase. Journal of Lipid Research, 22 (4), 675-679.
1981
Journal Article
Studies On Fat Digestion, Absorption, and Transport in the Suckling Rat .1. Fatty-Acid Composition and Concentrations of Major Lipid Components
Fernandowarnakulasuriya, Gjp, Staggers, JE, Frost, SC and Wells, MA (1981). Studies On Fat Digestion, Absorption, and Transport in the Suckling Rat .1. Fatty-Acid Composition and Concentrations of Major Lipid Components. Journal of Lipid Research, 22 (4), 668-674.
Funding
Supervision
Availability
- Dr Germain Fernando is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
-
Development of needle-free pain-free skin patch vaccines
1). Delivering of vaccines using a novel skin patch that is needle-free and pain-free which induces potent immune responses. Study of mechanisms.
2). Developing Universal Influenza Vaccines that protect people from new strains of virus.
3). Translating the skin patch vaccine delivery system from animal models to human clinical testing.
Supervision history
Completed supervision
-
2017
Doctor Philosophy
Systems Vaccinology studies on the biomolecular basis of physical adjuvantation in skin when vaccinated with a high density microprojection array
Associate Advisor
-
2012
Doctor Philosophy
Dissolving Nanopatches for Targeted Vaccine Delivery to the Skin
Associate Advisor
Media
Enquiries
Contact Dr Germain Fernando directly for media enquiries about:
- Anti-cancer Vaccines
- Antibody
- Biochemistry
- Drug Delivery
- Immunisation
- Immunology
- Influenza vaccines
- Lipid Chemistry
- Lipoproteins
- Medical Devices
- Nanopatch
- Needle-free vaccination
- Papillomavirus Vaccines
- Protein Chemistry
- Skin - vaccinations
- Systems Vaccinology
- T-Cells
- Vaccination
- Vaccine Adjuvants
- Vaccine delivery
- Vaccines
- Vaccines and genes
- Viral Vaccines
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