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2014 Journal Article Modulating the stem cell niche for tissue regenerationLane, Steven W., Williams, David A. and Watt, Fiona M. (2014). Modulating the stem cell niche for tissue regeneration. Nature Biotechnology, 32 (8), 795-803. doi: 10.1038/nbt.2978 |
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2014 Journal Article Sorafenib priming may augment salvage chemotherapy in relapsed and refractory FLT3-ITD-positive acute myeloid leukemiaCummins, K. D., Jane, S. M., Ninkovic, S., Bazargan, A., Filshie, R., Sutrave, G., Hertzberg, M., Scott, A., Lane, S., Yannakou, C. K., Ritchie, D., D'Rozario, J., Black, J., Bavishi, K. and Wei, A. (2014). Sorafenib priming may augment salvage chemotherapy in relapsed and refractory FLT3-ITD-positive acute myeloid leukemia. Blood Cancer Journal, 4 (e237) e237, 1-2. doi: 10.1038/bcj.2014.59 |
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2014 Journal Article Cost-Effectiveness of Pharmacogenetics-Guided Warfarin Therapy vs. Alternative Anticoagulation in Atrial FibrillationPink, J., Pirmohamed, M., Lane, S. and Hughes, D. A. (2014). Cost-Effectiveness of Pharmacogenetics-Guided Warfarin Therapy vs. Alternative Anticoagulation in Atrial Fibrillation. Clinical Pharmacology & Therapeutics, 95 (2), 199-207. doi: 10.1038/clpt.2013.190 |
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2014 Journal Article The Apcmin mouse has altered hematopoietic stem cell function and provides a model for MPD/MDSLane, S. W., Sykes, S. M., Al-Shahrour, F., Shterental, S., Paktinat, M., Lo Celso, C., Jesneck, J. L., Ebert, B. L., Williams, D. A. and Gilliland, D. Gary (2014). The Apcmin mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS. Blood, 123 (2), 301-301. doi: 10.1182/blood-2013-11-540047 |
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2013 Journal Article The cell fate determinant Llgl1 influences HSC fitness and prognosis in AMLHeidel, Florian H., Bullinger, Lars, Arreba-Tutusaus, Patricia, Wang, Zhu, Gaebel, Julia, Hirt, Carsten, Niederwieser, Dietger, Lane, Steven W., Doehner, Konstanze, Vasioukhin, Valera, Fischer, Thomas and Armstrong, Scott A. (2013). The cell fate determinant Llgl1 influences HSC fitness and prognosis in AML. Journal of Experimental Medicine, 210 (1), 15-22. doi: 10.1084/jem.20120596 |
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2013 Journal Article Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivoZhang, Ping, Tey, Siok-Keen, Koyama, Motoko, Kuns, Rachel D., Olver, Stuart D., Lineburg, Katie E., Lor, Mary, Teal, Bianca E., Raffelt, Neil C., Raju, Jyothy, Leveque, Lucie, Markey, Kate A., Varelias, Antiopi, Clouston, Andrew D., Lane, Steven W., Macdonald, Kelli P. A. and Hill, Geoffrey R. (2013). Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo. Journal of Immunology, 191 (10), 5291-5303. doi: 10.4049/jimmunol.1301181 |
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2013 Journal Article Deciphering hematopoietic stem cells in their niches: a critical appraisal of genetic models, lineage tracing, and imaging strategiesJoseph, Chacko, Quach, Julie M., Walkley, Carl R., Lane, Steven W., Lo Celso, Cristina and Purton, Louise E. (2013). Deciphering hematopoietic stem cells in their niches: a critical appraisal of genetic models, lineage tracing, and imaging strategies. Cell Stem Cell, 13 (5), 520-533. doi: 10.1016/j.stem.2013.10.010 |
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2013 Journal Article Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-alpha in a murine model of polycythemia veraMullally, Ann, Bruedigam, Claudia, Poveromo, Luke, Heidel, Florian H., Purdon, Amy, Vu, Therese, Austin, Rebecca, Heckl, Dirk, Breyfogle, Lawrence J., Kuhn, Catherine Paine, Kalaitzidis, Demetrios, Armstrong, Scott A., Williams, David A., Hill, Geoff R., Ebert, Benjamin L. and Lane, Steven W. (2013). Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-alpha in a murine model of polycythemia vera. Blood, 121 (18), 3692-3702. doi: 10.1182/blood-2012-05-432989 |
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2013 Journal Article Jak2V617F myeloproliferative neoplasm stem cells and interferon-alphaLane, Steven W. and Mullally, Ann (2013). Jak2V617F myeloproliferative neoplasm stem cells and interferon-alpha. Oncotarget, 4 (4), 500-501. doi: 10.18632/oncotarget.986 |
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2013 Journal Article The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftmentDorrance, Adrienne M., De Vita, Serena, Radu, Maria, Reddy, Pavankumar N. G., McGuinness, Meaghan K., Harris, Chad E., Mathieu, Ronald, Lane, Steven W., Kosoff, Rachelle, Milsom, Michael D., Chernoff, Jonathan and Williams, David A. (2013). The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment. Blood, 121 (13), 2474-2482. doi: 10.1182/blood-2012-10-460709 |
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2013 Journal Article Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacyColeman, Miranda A., Bridge, Jennifer A., Lane, Steven W., Dixon, Chantelle M., Hill, Geoffrey R., Wells, James W., Thomas, Ranjeny and Steptoe, Raymond J. (2013). Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy. Blood, 121 (6), 1049-1058. doi: 10.1182/blood-2012-06-434100 |
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2013 Journal Article CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signalingFaber, Katrin, Bullinger, Lars, Ragu, Christine, Garding, Angela, Mertens, Daniel, Miller, Christina, Martin, Daniela, Walcher, Daniel, Doehner, Konstanze, Doehner, Hartmut, Claus, Rainer, Plass, Christoph, Sykes, Stephen M., Lane, Steven W., Scholl, Claudia and Froehling, Stefan (2013). CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling. Journal of Clinical Investigation, 123 (1), 299-314. doi: 10.1172/JCI64745 |
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2012 Journal Article Myeloproliferative Neoplasm Animal ModelsMullally, Ann, Lane, Steven W., Brumme, Kristina and Ebert, Benjamin L. (2012). Myeloproliferative Neoplasm Animal Models. Hematology/Oncology Clinics of North America, 26 (5), 1065-1081. doi: 10.1016/j.hoc.2012.07.007 |
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2012 Journal Article mTOR complex 1 plays critical roles in hematopoiesis and pten-loss-evoked leukemogenesisKalaitzidis, Demetrios, Sykes, Stephen M., Wang, Zhu, Punt, Natalie, Tang, Yuefeng, Ragu, Christine, Sinha, Amit U., Lane, Steven W., Souza, Amanda L., Clish, Clary B., Anastasiou, Dimitrios, Gilliland, D. Gary, Scadden, David T., Guertin, David A. and Armstrong, Scott A. (2012). mTOR complex 1 plays critical roles in hematopoiesis and pten-loss-evoked leukemogenesis. Cell Stem Cell, 11 (3), 429-439. doi: 10.1016/j.stem.2012.06.009 |
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2012 Journal Article Distinct roles for long-term hematopoietic stem cells and erythroid precursor cells in a murine model of Jak2V617F-mediated polycythemia veraMullally, Ann, Poveromo, Luke, Schneider, Rebekka K., Al-Shahrour, Fatima, Lane, Steven W. and Ebert, Benjamin L. (2012). Distinct roles for long-term hematopoietic stem cells and erythroid precursor cells in a murine model of Jak2V617F-mediated polycythemia vera. Blood, 120 (1), 166-172. doi: 10.1182/blood-2012-01-402396 |
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2012 Journal Article Valproic acid combined with cytosine arabinoside in elderly patients with acute myeloid leukemia has in vitro but limited clinical activityLane, Steven, Gill, Devinder, McMillan, Nigel A. J., Saunders, Nicholas, Murphy, Rachel, Spurr, Terrence, Keane, Colm, Fan, Helen Mar and Mollee, Peter (2012). Valproic acid combined with cytosine arabinoside in elderly patients with acute myeloid leukemia has in vitro but limited clinical activity. Leukemia & Lymphoma, 53 (6), 1077-1083. doi: 10.3109/10428194.2011.642302 |
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2012 Journal Article WT1 expression as a marker of minimal residual disease predicts outcome in acute myeloid leukemia when measured post-consolidationGray, James X., McMillen, Lyle, Mollee, Peter, Paul, Sanjoy, Lane, Steven, Bird, Robert, Gill, Devinder, Saal, Russell and Marlton, Paula (2012). WT1 expression as a marker of minimal residual disease predicts outcome in acute myeloid leukemia when measured post-consolidation. Leukemia Research, 36 (4), 453-458. doi: 10.1016/j.leukres.2011.09.005 |
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2012 Journal Article Genetic and pharmacologic inhibition of beta-catenin targets imatinib-resistant leukemia stem cells in CMLHeidel, Florian H., Bullinger, Lars, Feng, Zhaohui, Wang, Zhu, Neff, Tobias A., Stein, Lauren, Kalaitzidis, Demetrios, Lane, Steve W. and Armstrong, Scott A. (2012). Genetic and pharmacologic inhibition of beta-catenin targets imatinib-resistant leukemia stem cells in CML. Cell Stem Cell, 10 (4), 412-424. doi: 10.1016/j.stem.2012.02.017 |
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2012 Journal Article Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic developmentLane, Steven W., De Vita, Serena, Alexander, Kylie A., Karaman, Ruchan, Milsom, Michael D., Dorrance, Adrienne M., Purdon, Amy, Louis, Leeann, Bouxsein, Mary L. and Williams, David A. (2012). Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development. Blood, 119 (3), 736-744. doi: 10.1182/blood-2011-07-368753 |
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2012 Journal Article Bad to the boneLane, Steven W. (2012). Bad to the bone. Blood, 119 (2), 323-325. doi: 10.1182/blood-2011-10-383901 |
