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2024

Journal Article

CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targeting

Lim, Kelly, Kan, Winnie L., Nair, Pramod C., Kutyna, Monika, Lopez, Angel F., Hercus, Timothy, Ross, David M., Lane, Steven, Fong, Chun Yew, Brown, Anna, Yong, Agnes, Yeung, David, Hughes, Timothy, Hiwase, Devendra and Thomas, Daniel (2024). CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targeting. PLoS One, 19 (9 September) e0310641, 1-19. doi: 10.1371/journal.pone.0310641

CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targeting

2024

Journal Article

Identifying disease-modifying potential in myelofibrosis clinical trials

Ross, David M, Lane, Steven W and Harrison, Claire N. (2024). Identifying disease-modifying potential in myelofibrosis clinical trials. Blood Journal, 144 (16), 1679-1688. doi: 10.1182/blood.2024024220

Identifying disease-modifying potential in myelofibrosis clinical trials

2024

Journal Article

Asciminib monotherapy as frontline treatment of chronic-phase chronic myeloid leukemia: results from the ASCEND Study

Yeung, David T., Shanmuganathan, Naranie, Reynolds, John, Branford, Susan, Walia, Mannu, Yong, Agnes S.M., Shortt, Jake, Chee, Lynette, Viiala, Nicholas, Cunningham, Ilona, Ross, David M., D'Souza, Alwyn Bernard, Wright, Matthew, Harrup, Rosemary Anne, Forsyth, Cecily Jane, Filshie, Robin, Lane, Steven W., Browett, Peter J., Grove, Carolyn S., Grigg, Andrew A. and Hughes, Timothy P. (2024). Asciminib monotherapy as frontline treatment of chronic-phase chronic myeloid leukemia: results from the ASCEND Study. Blood Journal, 144 (19), 1993-2001. doi: 10.1182/blood.2024024657

Asciminib monotherapy as frontline treatment of chronic-phase chronic myeloid leukemia: results from the ASCEND Study

2024

Journal Article

Microclots, as defined by amyloid-fibrinogen aggregates, predict risks of disseminated intravascular coagulation and mortality

Scho, Jeremy, Abrams, Simon T., Jenkins, Rosalind, Lane, Steven, Wang, Guozheng and Toh, Cheng-Hock (2024). Microclots, as defined by amyloid-fibrinogen aggregates, predict risks of disseminated intravascular coagulation and mortality. Blood Advances, 8 (10), 2499-2508. doi: 10.1182/bloodadvances.2023012473

Microclots, as defined by amyloid-fibrinogen aggregates, predict risks of disseminated intravascular coagulation and mortality

2024

Journal Article

Autophagy prevents graft failure during murine Graft versus Host Disease

Lineburg, Katie E., Leveque-El Mouttie, Lucie, Hunter, Christopher R., Le Texier, Laeitia, McGirr, Crystal, Teal, Bianca, Blazar, Bruce R., Lane, Steven W., Hill, Geoffrey R., Levesque, Jean-Pierre and MacDonald, Kelli P.A. (2024). Autophagy prevents graft failure during murine Graft versus Host Disease. Blood Advances, 8 (8), 2032-2043. doi: 10.1182/bloodadvances.2023010972

Autophagy prevents graft failure during murine Graft versus Host Disease

2024

Journal Article

Survival for the fittest: guadecitabine in rel/ref AML

Sheehy, Joshua and Lane, Steven W. (2024). Survival for the fittest: guadecitabine in rel/ref AML. Blood Advances, 8 (8), 2018-2019. doi: 10.1182/bloodadvances.2024012569

Survival for the fittest: guadecitabine in rel/ref AML

2024

Journal Article

Australia and New Zealand consensus position statement: use of COVID-19 therapeutics in patients with haematological malignancies

Campbell, Ashlea, Teh, Benjamin, Mulligan, Stephen, Ross, David M., Weinkove, Robert, Gilroy, Nicole, Gangatharan, Shane, Prince, Henry Miles, Szer, Jeff, Trotman, Judith, Lane, Steven, Dickinson, Michael, Quach, Hang, Enjeti, Anoop K., Ku, Matthew, Gregory, Gareth, Hapgood, Gregory, Ho, Phoebe Joy, Cochrane, Tara, Cheah, Chan, Greenwood, Matthew, Latimer, Maya, Berkahn, Leanne, Wight, Joel, Armytage, Tasman, Diamond, Peter, Tam, Constantine S. and Hamad, Nada (2024). Australia and New Zealand consensus position statement: use of COVID-19 therapeutics in patients with haematological malignancies. Internal Medicine Journal, 54 (2), 328-336. doi: 10.1111/imj.16303

Australia and New Zealand consensus position statement: use of COVID-19 therapeutics in patients with haematological malignancies

2024

Journal Article

Low iodine nutrition knowledge in Chinese breastfeeding women despite adequate iodine status

Liu, Shuchang, Sharp, Andrew, Lane, Steven, Villanueva, Elmer V., Lu, Zhiliang and Ma, Zheng Feei (2024). Low iodine nutrition knowledge in Chinese breastfeeding women despite adequate iodine status. Nutrients, 16 (4) 491, 1-14. doi: 10.3390/nu16040491

Low iodine nutrition knowledge in Chinese breastfeeding women despite adequate iodine status

2024

Journal Article

A randomised double-blind placebo-controlled trial of minocycline and/or omega-3 fatty acids added to treatment as usual for at risk Mental States: The NAYAB study

Qurashi, Inti, Chaudhry, Imran B., Khoso, Ameer B., Husain, Muhammad Omair, Hafeez, Danish, Kiran, Tayyeba, Lane, Steven, Naqvi, Haider A., Minhas, Fareed A., Nizami, Asad Tamizuddin, Razzaque, Bushra, Bokhari, Sumira Qambar, Yung, Alison R., Deakin, Bill and Husain, Nusrat (2024). A randomised double-blind placebo-controlled trial of minocycline and/or omega-3 fatty acids added to treatment as usual for at risk Mental States: The NAYAB study. Brain Behavior and Immunity, 115, 609-616. doi: 10.1016/j.bbi.2023.10.025

A randomised double-blind placebo-controlled trial of minocycline and/or omega-3 fatty acids added to treatment as usual for at risk Mental States: The NAYAB study

2024

Journal Article

Imetelstat-mediated alterations in fatty acid metabolism to induce ferroptosis as a therapeutic strategy for acute myeloid leukemia

Bruedigam, Claudia, Porter, Amy H., Song, Axia, Vroeg in de Wei, Gerjanne, Stoll, Thomas, Straube, Jasmin, Cooper, Leanne, Cheng, Guidan, Kahl, Vivian F. S., Sobinoff, Alexander P., Ling, Victoria Y., Jebaraj, Billy Michael Chelliah, Janardhanan, Yashaswini, Haldar, Rohit, Bray, Laura J., Bullinger, Lars, Heidel, Florian H., Kennedy, Glen A., Hill, Michelle M., Pickett, Hilda A., Abdel-Wahab, Omar, Hartel, Gunter and Lane, Steven W. (2024). Imetelstat-mediated alterations in fatty acid metabolism to induce ferroptosis as a therapeutic strategy for acute myeloid leukemia. Nature Cancer, 5 (1), 47-65. doi: 10.1038/s43018-023-00653-5

Imetelstat-mediated alterations in fatty acid metabolism to induce ferroptosis as a therapeutic strategy for acute myeloid leukemia

2023

Journal Article

Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia

Tubio-Santamaria, Nuria, Jayavelu, Ashok Kumar, Schnoeder, Tina M., Eifert, Theresa, Hsu, Chen-Jen, Perner, Florian, Zhang, Qirui, Wenge, Daniela V., Hansen, Fynn M., Kirkpatrick, Joanna M., Jyotsana, Nidhi, Lane, Steven W., von Eyss, Bjoern, Deshpande, Aniruddha J., Kuehn, Michael W. M., Schwaller, Juerg, Cammann, Clemens, Seifert, Ulrike, Ebstein, Frederic, Krueger, Elke, Hochhaus, Andreas, Heuser, Michael, Ori, Alessandro, Mann, Matthias, Armstrong, Scott A. and Heidel, Florian H. (2023). Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia. Molecular Cancer, 22 (1) 196. doi: 10.1186/s12943-023-01907-7

Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia

2023

Journal Article

Clearing the way for new therapies in clonal hematopoiesis

Ling, Victoria Y. and Lane, Steven W. (2023). Clearing the way for new therapies in clonal hematopoiesis. Blood Advances, 7 (22), 7151-7152. doi: 10.1182/bloodadvances.2023011728

Clearing the way for new therapies in clonal hematopoiesis

2023

Journal Article

Demographic, clinical and laboratory differences between paediatric acute COVID-19 and PIMS-TS-results from a single centre study in the UK

Jiju, Prince, Matalliotakis, Michail, Lane, Steven, Wong, Waison, Hedrich, Christian M. and Pain, Clare E. (2023). Demographic, clinical and laboratory differences between paediatric acute COVID-19 and PIMS-TS-results from a single centre study in the UK. Frontiers in Pediatrics, 11 1219654, 1-11. doi: 10.3389/fped.2023.1219654

Demographic, clinical and laboratory differences between paediatric acute COVID-19 and PIMS-TS-results from a single centre study in the UK

2023

Journal Article

Genome-wide transcription factor binding maps reveal cell-specific changes in the regulatory architecture of human HSPC

Subramanian, Shruthi, Thoms, Julie A I, Huang, Yizhou, Cornejo Paramo, Carina Paola, Koch, Forrest Charles, Jacquelin, Sebastien, Shen, Sylvie, Song, Emma, Joshi, Swapna, Brownlee, Christopher Peter, Woll, Petter S., Chacon-Fajardo, Diego, Beck, Dominik, Curtis, David J, Yehson, Kenneth, Antonenas, Vicki, O'Brien, Tracey, Trickett, Annette, Powell, Jason A., Lewis, Ian D, Pitson, Stuart M, Gandhi, Maher K., Lane, Steven W, Vafaee, Fatemeh, Wong, Emily, Gottgens, Berthold, Rokny, Hamid, Wong, Jason Wing Hon and Pimanda, John E (2023). Genome-wide transcription factor binding maps reveal cell-specific changes in the regulatory architecture of human HSPC. Blood Journal, 142 (17), 1448-1462. doi: 10.1182/blood.2023021120

Genome-wide transcription factor binding maps reveal cell-specific changes in the regulatory architecture of human HSPC

2023

Journal Article

Evaluation of a novel, multicomponent anxiety management programme for people with intellectual disability: protocol for a mixed-methods, quasi-experimental feasibility study

Acton, Daniel, Williams, Jonathan, Woodrow, Ceri, Talbot, Grace, Jones, Steven, Lane, Steven and Jaydeokar, Sujeet (2023). Evaluation of a novel, multicomponent anxiety management programme for people with intellectual disability: protocol for a mixed-methods, quasi-experimental feasibility study. BMJ Open, 13 (9) e078411, 9. doi: 10.1136/bmjopen-2023-078411

Evaluation of a novel, multicomponent anxiety management programme for people with intellectual disability: protocol for a mixed-methods, quasi-experimental feasibility study

2023

Journal Article

The use of breast milk iodine concentration in the first week of lactation as a biomarker of iodine status in breast-feeding women

Liu, Shuchang, Sharp, Andrew, Luo, Xiaoqin, Lane, Steven, Villanueva, Elmer V., Lu, Zhiliang and Ma, Zheng Feei (2023). The use of breast milk iodine concentration in the first week of lactation as a biomarker of iodine status in breast-feeding women. British Journal of Nutrition, 131 (2), 286-295. doi: 10.1017/S0007114523001897

The use of breast milk iodine concentration in the first week of lactation as a biomarker of iodine status in breast-feeding women

2023

Journal Article

ACTivity as medicine In Oncology for Head and Neck (ACTIOHN): protocol for a feasibility study investigating a patient-centred approach to exercise for people with head and neck cancer

Midgley, Adrian W., Levy, Andrew R., Rogers, Simon N., Brooker, Rachel C., Bryant, Valerie, Cherry, Mary Gemma, Lane, Steven, Nugent, Michael M., Price, Ruth, Schache, Andrew G., Young, Bridget and Patterson, Joanne M. (2023). ACTivity as medicine In Oncology for Head and Neck (ACTIOHN): protocol for a feasibility study investigating a patient-centred approach to exercise for people with head and neck cancer. PLoS One, 18 (8) e0289911, 1-20. doi: 10.1371/journal.pone.0289911

ACTivity as medicine In Oncology for Head and Neck (ACTIOHN): protocol for a feasibility study investigating a patient-centred approach to exercise for people with head and neck cancer

2023

Journal Article

Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia

Eifert, Theresa, Hsu, Chen-Jen, Becker, Alicia L., Graessle, Sarah, Horne, Arik, Bemmann, Franziska, Zhang, Qirui, Heuser, Michael, Vasioukhin, Valeri, Scholl, Sebastian, Hochhaus, Andreas, Siegerist, Florian, Endlich, Nicole, Bullinger, Lars, Lane, Steven W., Haas, Simon, Schnoeder, Tina M. and Heidel, Florian H. (2023). Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia. Leukemia, 37 (10), 2027-2035. doi: 10.1038/s41375-023-02005-9

Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia

2023

Journal Article

The TRIM31-paradox: an unexpected benefit for leukemia stem cells

Straube, Jasmin and Lane, Steven W. (2023). The TRIM31-paradox: an unexpected benefit for leukemia stem cells. Haematologica, 108 (8), 1982-1983. doi: 10.3324/haematol.2022.282622

The TRIM31-paradox: an unexpected benefit for leukemia stem cells

2023

Journal Article

Follow up of women after obstetric anal sphincter injuries (OASI)-what is the role of anorectal testing?

Badri, Hawra, Fowler, Gillian and Lane, Steven (2023). Follow up of women after obstetric anal sphincter injuries (OASI)-what is the role of anorectal testing?. Neurourology and Urodynamics, 42 (6), 1374-1380. doi: 10.1002/nau.25220

Follow up of women after obstetric anal sphincter injuries (OASI)-what is the role of anorectal testing?