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2020

Journal Article

Parasite histories are toxic to brain endothelium and link blood barrier breakdown and thrombosis in cerebral malaria

Moxon, Christopher A., Alhamdi, Yasir, Storm, Janet, Toh, Julien M. H., McGuinness, Dagmara, Ko, Joo Yeon, Murphy, George, Lane, Steven, Taylor, Terrie E., Seydel, Karl B., Kampondeni, Sam, Potchen, Michael, O'Donnell, James S., O'Regan, Niamh, Wang, Guozheng, Garcia-Cardena, Guillermo, Molyneux, Malcolm, Craig, Alister G., Abrams, Simon T. and Toh, Cheng-Hock (2020). Parasite histories are toxic to brain endothelium and link blood barrier breakdown and thrombosis in cerebral malaria. Blood Advances, 4 (13), 2851-2864. doi: 10.1182/bloodadvances.2019001258

Parasite histories are toxic to brain endothelium and link blood barrier breakdown and thrombosis in cerebral malaria

2020

Journal Article

Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia

Vu, Therese, Straube, Jasmin, Porter, Amy H., Bywater, Megan, Song, Axia, Ling, Victoria, Cooper, Leanne, Pali, Gabor, Bruedigam, Claudia, Jacquelin, Sebastien, Green, Joanne, Magor, Graham, Perkins, Andrew, Chalk, Alistair M., Walkley, Carl R., Heidel, Florian H., Mukhopadhyay, Pamela, Cloonan, Nicole, Gröschel, Stefan, Mallm, Jan-Philipp, Fröhling, Stefan, Scholl, Claudia and Lane, Steven W. (2020). Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia. Nature Communications, 11 (1) 3021, 3021. doi: 10.1038/s41467-020-16840-2

Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia

2020

Journal Article

Managing haematology and oncology patients during the COVID-19 pandemic: interim consensus guidance

Weinkove, Robert, McQuilten, Zoe K, Adler, Jonathan, Agar, Meera R, Blyth, Emily, Cheng, Allen C, Conyers, Rachel, Haeusler, Gabrielle M, Hardie, Claire, Jackson, Christopher, Lane, Steven W, Middlemiss, Tom, Mollee, Peter, Mulligan, Stephen P, Ritchie, David, Ruka, Myra, Solomon, Benjamin, Szer, Jeffrey, Thursky, Karin A, Wood, Erica M, Worth, Leon J, Yong, Michelle K, Slavin, Monica A and Teh, Benjamin W (2020). Managing haematology and oncology patients during the COVID-19 pandemic: interim consensus guidance. Medical Journal of Australia, 212 (10) mja2.50607, 481-489. doi: 10.5694/mja2.50607

Managing haematology and oncology patients during the COVID-19 pandemic: interim consensus guidance

2020

Journal Article

Being 'at-home' on outpatient parenteral antimicrobial therapy (OPAT): a qualitative study of parents' experiences of paediatric OPAT

Carter, Bernie, Fisher-Smith, Debra, Porter, David, Lane, Steven, Peak, Matthew, Taylor-Robinson, David, Bracken, Louise and Carrol, Enitan (2020). Being 'at-home' on outpatient parenteral antimicrobial therapy (OPAT): a qualitative study of parents' experiences of paediatric OPAT. Archives of Disease in Childhood, 105 (3), 276-281. doi: 10.1136/archdischild-2019-317629

Being 'at-home' on outpatient parenteral antimicrobial therapy (OPAT): a qualitative study of parents' experiences of paediatric OPAT

2020

Journal Article

Type I interferons suppress anti-parasitic immunity and can be targeted to improve treatment of visceral leishmaniasis

Kumar, Rajiv, Bunn, Patrick T., Singh, Siddharth Sankar, Ng, Susanna S., Montes de Oca, Marcela, De Labastida Rivera, Fabian, Chauhan, Shashi Bhushan, Singh, Neetu, Faleiro, Rebecca J., Edwards, Chelsea L., Frame, Teija C.M., Sheel, Meru, Austin, Rebecca J., Lane, Steven W., Bald, Tobias, Smyth, Mark J., Hill, Geoffrey.R., Best, Shannon E., Haque, Ashraful, Corvino, Dillon, Waddell, Nic, Koufariotis, Lambross, Mukhopadhay, Pamela, Rai, Madhukar, Chakravarty, Jaya, Singh, Om Prakash, Sacks, David, Nylen, Susanne, Uzonna, Jude ... Engwerda, Christian R. (2020). Type I interferons suppress anti-parasitic immunity and can be targeted to improve treatment of visceral leishmaniasis. Cell Reports, 30 (8), 2512-2525.e9. doi: 10.1016/j.celrep.2020.01.099

Type I interferons suppress anti-parasitic immunity and can be targeted to improve treatment of visceral leishmaniasis

2020

Journal Article

Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory

Soon, Megan S. F., Lee, Hyun Jae, Engel, Jessica A., Straube, Jasmin, Thomas, Bryce S., Pernold, Clara P. S., Clarke, Lachlan S., Laohamonthonkul, Pawat, Haldar, Rohit N., Williams, Cameron G., Lansink, Lianne I. M., Moreira, Marcela L., Bramhall, Michael, Koufariotis, Lambros T., Wood, Scott, Chen, Xi, James, Kylie R., Lönnberg, Tapio, Lane, Steven W., Belz, Gabrielle T., Engwerda, Christian R., Khoury, David S., Davenport, Miles P., Svensson, Valentine, Teichmann, Sarah A. and Haque, Ashraful (2020). Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory. Nature Immunology, 21 (12), 1597-1610. doi: 10.1038/s41590-020-0800-8

Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory

2020

Journal Article

Mapping functional susceptibilities in AML

Lane, Steven and Henden, Andrea (2020). Mapping functional susceptibilities in AML. The Hematologist, 17 (1). doi: 10.1182/hem.v17.1.10162

Mapping functional susceptibilities in AML

2019

Journal Article

Distinct effects of ruxolitinib and interferon-alpha on murine JAK2V617F myeloproliferative neoplasm hematopoietic stem cell populations

Austin, Rebecca J., Straube, Jasmin, Bruedigam, Claudia, Pali, Gabor, Jacquelin, Sebastien, Vu, Therese, Green, Joanne, Gräsel, Julius, Lansink, Lianne, Cooper, Leanne, Lee, Shin-Jye, Chen, Nien-Tsu, Lee, Chung-Wei, Haque, Ashraful, Heidel, Florian H., D’Andrea, Richard, Hill, Geoff R., Mullally, Ann, Milsom, Michael D., Bywater, Megan and Lane, Steven W. (2019). Distinct effects of ruxolitinib and interferon-alpha on murine JAK2V617F myeloproliferative neoplasm hematopoietic stem cell populations. Leukemia, 34 (4), 1075-1089. doi: 10.1038/s41375-019-0638-y

Distinct effects of ruxolitinib and interferon-alpha on murine JAK2V617F myeloproliferative neoplasm hematopoietic stem cell populations

2019

Journal Article

Inflammation in del(20q): a MST opportunity?

Lane, Steven W. (2019). Inflammation in del(20q): a MST opportunity?. Blood, 134 (20), 1685-1686. doi: 10.1182/blood.2019003028

Inflammation in del(20q): a MST opportunity?

2019

Journal Article

Dynamic Electronic Tracking and Escalation to reduce Critical care Transfers (DETECT): the protocol for a stepped wedge mixed method study to explore the clinical effectiveness, clinical utility and cost-effectiveness of an electronic physiological surveillance system for use in children

Sefton, Gerri, Carter, Bernie, Lane, Steven, Peak, Matthew, Mateus, Ceu, Preston, Jen, Mehta, Fulya, Hollingsworth, Bruce, Killen, Roger and Carrol, Enitan D. (2019). Dynamic Electronic Tracking and Escalation to reduce Critical care Transfers (DETECT): the protocol for a stepped wedge mixed method study to explore the clinical effectiveness, clinical utility and cost-effectiveness of an electronic physiological surveillance system for use in children. Bmc Pediatrics, 19 (1) 359. doi: 10.1186/s12887-019-1745-7

Dynamic Electronic Tracking and Escalation to reduce Critical care Transfers (DETECT): the protocol for a stepped wedge mixed method study to explore the clinical effectiveness, clinical utility and cost-effectiveness of an electronic physiological surveillance system for use in children

2019

Journal Article

A comparison of angina symptoms reported by clinicians and patients, pre and post revascularisation: Insights from the Stent or Surgery Trial

Kemp, I., Appleby, C., Lane, S., Lisboa, P. and Stables, R. H. (2019). A comparison of angina symptoms reported by clinicians and patients, pre and post revascularisation: Insights from the Stent or Surgery Trial. International Journal of Cardiology, 293, 25-31. doi: 10.1016/j.ijcard.2019.06.052

A comparison of angina symptoms reported by clinicians and patients, pre and post revascularisation: Insights from the Stent or Surgery Trial

2019

Journal Article

Acute promyelocytic leukaemia with marked symptomatic hyperleucocytosis: images in haematology

Yuan, Yin, Mediwake, Heshani, Bokhari, Syed W., Holley, Anthony and Lane, Steven W. (2019). Acute promyelocytic leukaemia with marked symptomatic hyperleucocytosis: images in haematology. British Journal of Haematology, 186 (5), 649-649. doi: 10.1111/bjh.16016

Acute promyelocytic leukaemia with marked symptomatic hyperleucocytosis: images in haematology

2019

Journal Article

Recommendations for the use of pegylated interferon-α in the treatment of classical myeloproliferative neoplasms

Forsyth, Cecily J., Chan, Wai-Hoong, Grigg, Andrew P., Cook, Nathalie C., Lane, Steven W., Burbury, Kate L., Perkins, Andrew C. and Ross, David M. (2019). Recommendations for the use of pegylated interferon-α in the treatment of classical myeloproliferative neoplasms. Internal Medicine Journal, 49 (8), 948-954. doi: 10.1111/imj.14154

Recommendations for the use of pegylated interferon-α in the treatment of classical myeloproliferative neoplasms

2019

Journal Article

Attenuated acceleration to leukemia after Ezh2 loss in Nup98-HoxD13 (NHD13) myelodysplastic syndrome

Ling, Victoria Y., Saw, Jesslyn, Tremblay, Cedric S., Sonderegger, Stefan E., Toulmin, Emma, Boyle, Jacqueline, Chiu, Sung Kai, Lane, Steven W., Ting, Stephen B. and Curtis, David J. (2019). Attenuated acceleration to leukemia after Ezh2 loss in Nup98-HoxD13 (NHD13) myelodysplastic syndrome. HemaSphere, 3 (4) e277, e277. doi: 10.1097/HS9.0000000000000277

Attenuated acceleration to leukemia after Ezh2 loss in Nup98-HoxD13 (NHD13) myelodysplastic syndrome

2018

Journal Article

Impact of Non-Adherence and Flare Resolution on the Cost-Effectiveness of Treatments for Gout: Application of a Linked Pharmacometric/Pharmacoeconomic Model

Hill-McManus, Daniel, Marshall, Scott, Soto, Elena, Lane, Steven and Hughes, Dyfrig (2018). Impact of Non-Adherence and Flare Resolution on the Cost-Effectiveness of Treatments for Gout: Application of a Linked Pharmacometric/Pharmacoeconomic Model. Value in Health, 21 (12), 1373-1381. doi: 10.1016/j.jval.2018.06.002

Impact of Non-Adherence and Flare Resolution on the Cost-Effectiveness of Treatments for Gout: Application of a Linked Pharmacometric/Pharmacoeconomic Model

2018

Journal Article

Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation

Jacquelin, Sebastien, Straube, Jasmin, Cooper, Leanne, Vu, Therese, Song, Axia, Bywater, Megan, Baxter, Eva, Heidecker, Matthew, Wackrow, Brad, Porter, Amy, Ling, Victoria, Green, Joanne, Austin, Rebecca, Kazakoff, Stephen, Waddell, Nicola, Hesson, Luke B., Pimanda, John E., Stegelmann, Frank, Bullinger, Lars, Döhner, Konstanze, Rampal, Raajit K., Heckl, Dirk, Hill, Geoffrey R. and Lane, Steven W. (2018). Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation. Blood, 132 (26), blood-2018. doi: 10.1182/blood-2018-04-846220

Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation

2018

Journal Article

Recipient mucosal-associated invariant T cells control GVHD within the colon

Varelias, Antiopi, Bunting, Mark D., Ormerod, Kate L., Koyama, Motoko, Olver, Stuart D., Straube, Jasmin, Kuns, Rachel D., Robb, Renee J., Henden, Andrea S., Cooper, Leanne, Lachner, Nancy, Gartlan, Kate H., Lantz, Olivier, Kjer-Nielsen, Lars, Mak, Jeffrey Y. W., Fairlie, David P., Clouston, Andrew D., McCluskey, James, Rossjohn, Jamie, Lane, Steven W., Hugenholtz, Philip and Hill, Geoffrey R. (2018). Recipient mucosal-associated invariant T cells control GVHD within the colon. Journal of Clinical Investigation, 128 (5), 1919-1936. doi: 10.1172/JCI91646

Recipient mucosal-associated invariant T cells control GVHD within the colon

2018

Journal Article

Conventional dendritic cells are required for the cross-presentation of leukemia-specific antigen in a model of AML relapse post-BMT

Markey, Kate A., Gartlan, Kate H., Kuns, Rachel D., Lane, Steven W. and Hill, Geoffrey R. (2018). Conventional dendritic cells are required for the cross-presentation of leukemia-specific antigen in a model of AML relapse post-BMT. Bone Marrow Transplantation, 53 (6), 800-803. doi: 10.1038/s41409-018-0148-y

Conventional dendritic cells are required for the cross-presentation of leukemia-specific antigen in a model of AML relapse post-BMT

2018

Journal Article

The impact of age, NPM1, and FLT3 allelic ratio in patients with acute myeloid leukemia

Straube, Jasmin, Ling, Victoria Y, Hill, Geoffrey R and Lane, Steven W (2018). The impact of age, NPM1, and FLT3 allelic ratio in patients with acute myeloid leukemia. Blood, 131 (10), 1148-1153. doi: 10.1182/blood-2017-09-807438

The impact of age, NPM1, and FLT3 allelic ratio in patients with acute myeloid leukemia

2018

Journal Article

Oncogenic JAK2causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms

Prestipino, Alessandro, Emhardt, Alica J., Aumann, Konrad, O'Sullivan, David, Gorantla, Sivahari P., Duquesne, Sandra, Melchinger, Wolfgang, Braun, Lukas, Vuckovic, Slavica, Boerries, Melanie, Busch, Hauke, Halbach, Sebastian, Pennisi, Sandra, Poggio, Teresa, Apostolova, Petya, Veratti, Pia, Hettich, Michael, Niedermann, Gabriele, Bartholomä, Mark, Shoumariyeh, Khalid, Jutzi, Jonas S., Wehrle, Julius, Dierks, Christine, Becker, Heiko, Schmitt-Graeff, Annette, Follo, Marie, Pfeifer, Dietmar, Rohr, Jan, Fuchs, Sebastian ... Zeiser, Robert (2018). Oncogenic JAK2causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms. Science Translational Medicine, 10 (429) eaam7729, eaam7729. doi: 10.1126/scitranslmed.aam7729

Oncogenic JAK2causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms