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2017

Journal Article

Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress

Shi, Wei, Vu, Therese, Boucher, Didier, Biernacka, Anna, Nde, Jules, Pandita, Raj K., Straube, Jasmin, Boyle, Glen M., Al-Ejeh, Fares, Nag, Purba, Jeffery, Jessie, Harris, Janelle L., Bain, Amanda L., Grzelak, Marta, Skrzypczak, Magdalena, Mitra, Abhishek, Dojer, Norbert, Crosetto, Nicola, Cloonan, Nicole, Becherel, Olivier J., Finnie, John, Skaar, Jeffrey R., Walkley, Carl R., Pandita, Tej K., Rowicka, Maga, Ginalski, Krzysztof, Lane, Steven W. and Khanna, Kum Kum (2017). Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress. Blood, 129 (18), 2479-2492. doi: 10.1182/blood-2016-06-725093

Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress

2017

Journal Article

Global prevalence of carbapenem resistance in neutropenic patients and association with mortality and carbapenem use: systematic review and meta-analysis

Righi, Elda, Peri, Anna Maria, Harris, Patrick N. A., Wailan, Alexander M., Liborio, Mariana, Lane, Steven W. and Paterson, David L. (2017). Global prevalence of carbapenem resistance in neutropenic patients and association with mortality and carbapenem use: systematic review and meta-analysis. Journal of Antimicrobial Chemotherapy, 72 (3), 668-677. doi: 10.1093/jac/dkw459

Global prevalence of carbapenem resistance in neutropenic patients and association with mortality and carbapenem use: systematic review and meta-analysis

2017

Journal Article

GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity

Bunting, Mark D., Varelias, Antiopi, Souza-Fonseca-Guimaraes, Fernando, Schuster, Iona S., Lineburg, Katie E., Kuns, Rachel D., Fleming, Peter, Locke, Kelly R., Huntington, Nicholas D., Blazar, Bruce R., Lane, Steven W., Tey, Siok-Keen, MacDonald, Kelli P. A., Smyth, Mark J., Degli-Esposti, Mariapia A. and Hill, Geoffrey R. (2017). GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity. Blood, 129 (5), 630-642. doi: 10.1182/blood-2016-08-734020

GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity

2016

Journal Article

An unhealthy diet: making sense of a fatty niche for leukemia stem cells

Jacquelin, Sebastien, Dishington, Emma J. and Lane, Steven W. (2016). An unhealthy diet: making sense of a fatty niche for leukemia stem cells. Translational Cancer Research, 5 (S4), S878-S881. doi: 10.21037/tcr.2016.10.43

An unhealthy diet: making sense of a fatty niche for leukemia stem cells

2016

Journal Article

Harnessing the immune system in acute myeloid leukaemia

Austin, Rebecca, Smyth, Mark J. and Lane, Steven W. (2016). Harnessing the immune system in acute myeloid leukaemia. Critical Reviews in Oncology/Hematology, 103, 62-77. doi: 10.1016/j.critrevonc.2016.04.020

Harnessing the immune system in acute myeloid leukaemia

2016

Journal Article

Telomerase in hematologic malignancies

Bruedigam, Claudia and Lane, Steven W. (2016). Telomerase in hematologic malignancies. Current Opinion in Hematology, 23 (4), 346-353. doi: 10.1097/MOH.0000000000000252

Telomerase in hematologic malignancies

2016

Journal Article

Jak2V617F driven myeloproliferative neoplasm occurs independently of interleukin-3 receptor beta common signalling

Vu, Therese, Austin, Rebecca, Kuhn, Catherine Paine, Bruedigam, Claudia, Song, Axia, Guignes, Solene, Jacquelin, Sebastien, Ramshaw, Hayley S., Hill, Geoffrey R., Lopez, Angel F. and Lane, Steven W. (2016). Jak2V617F driven myeloproliferative neoplasm occurs independently of interleukin-3 receptor beta common signalling. Haematologica, 101 (3), E77-E80. doi: 10.3324/haematol.2015.136705

Jak2V617F driven myeloproliferative neoplasm occurs independently of interleukin-3 receptor beta common signalling

2016

Journal Article

Analysis of telomerase target gene expression effects from murine models in patient cohorts by homology translation and random survival forest modeling

Bagger, Frederik Otzen, Bruedigam, Claudia and Lane, Steven W. (2016). Analysis of telomerase target gene expression effects from murine models in patient cohorts by homology translation and random survival forest modeling. Genomics Data, 7, 275-280. doi: 10.1016/j.gdata.2016.01.014

Analysis of telomerase target gene expression effects from murine models in patient cohorts by homology translation and random survival forest modeling

2015

Journal Article

Increased risk of melanoma in patients with chronic lymphocytic leukaemia: systematic review and meta-analysis of cohort studies

Olsen, Catherine M., Lane, Steven W. and Green, Adèle C. (2015). Increased risk of melanoma in patients with chronic lymphocytic leukaemia: systematic review and meta-analysis of cohort studies. Melanoma Research, 26 (2), 188-194. doi: 10.1097/CMR.0000000000000219

Increased risk of melanoma in patients with chronic lymphocytic leukaemia: systematic review and meta-analysis of cohort studies

2015

Journal Article

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8<sup>+</sup> T cells that induce GVHD without antileukemic effects

Gartlan, Kate H., Markey, Kate A., Varelias, Antiopi, Bunting, Mark D., Koyama, Motoko, Kuns, Rachel D., Raffelt, Neil C., Olver, Stuart D., Lineburg, Katie E., Cheong, Melody, Teal, Bianca E., Lor, Mary, Comerford, Iain, Teng, Michele W. L., Smyth, Mark J., McCluskey, James, Rossjohn, Jamie, Stockinger, Brigitta, Boyle, Glen M., Lane, Steven W., Clouston, Andrew D., McColl, Shaun R., MacDonald, Kelli P. A. and Hill, Geoffrey R. (2015). Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects. Blood, 126 (13), 1609-1620. doi: 10.1182/blood-2015-01-622662

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8<sup>+</sup> T cells that induce GVHD without antileukemic effects

2015

Journal Article

BET inhibitor resistance emerges from leukaemia stem cells

Fong, Chun Yew, Gilan, Omer, Lam, Enid Y.N., Rubin, Alan F., Ftouni, Sarah, Tyler, Dean, Stanley, Kym, Sinha, Devbarna, Yeh, Paul, Morison, Jessica, Giotopoulos, George, Lugo, Dave, Jeffrey, Philip, Lee, Stanley Chun-Wei, Carpenter, Christopher, Gregory, Richard, Ramsay, Robert G., Lane, Steven W., Abdel-Wahab, Omar, Kouzarides, Tony, Johnstone, Ricky W., Dawson, Sarah-Jane, Huntly, Brian J.P., Prinjha, Rab K., Papenfuss, Anthony T. and Dawson, Mark A. (2015). BET inhibitor resistance emerges from leukaemia stem cells. Nature, 525 (7570), 538-542. doi: 10.1038/nature14888

BET inhibitor resistance emerges from leukaemia stem cells

2015

Journal Article

Ssb2/Nabp1 is dispensable for thymic maturation, male fertility, and DNA repair in mice

Boucher, Didier, Vu, Therese, Bain, Amanda L., Tagliaro-Jahns, Marina, Shi, Wei, Lane, Steven W. and Khanna, Kum Kum (2015). Ssb2/Nabp1 is dispensable for thymic maturation, male fertility, and DNA repair in mice. FASEB Journal, 29 (8), 3326-3334. doi: 10.1096/fj.14-269944

Ssb2/Nabp1 is dispensable for thymic maturation, male fertility, and DNA repair in mice

2015

Journal Article

EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia.

Charmsaz, Sara, Beckett, Kirrilee, Smith, Fiona M., Bruedigam, Claudia, Moore, Andrew S., Al-Ejeh, Fares, Lane, Steven W. and Boyd, Andrew W. (2015). EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia.. PLoS One, 10 (6) e0130692, e0130692-e0130692. doi: 10.1371/journal.pone.0130692

EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia.

2015

Journal Article

Autophagy is required for stem cell mobilization by G-CSF

Leveque-El Mouttie, Lucie, Vu, Therese, Lineburg, Katie E., Kuns, Rachel D., Bagger, Frederik O., Teal, Bianca E., Lor, Mary, Boyle, Glen M., Bruedigam, Claudia, Mintern, Justine D., Hill, Geoffrey R., MacDonald, Kelli P. A. and Lane, Steven W. (2015). Autophagy is required for stem cell mobilization by G-CSF. Blood, 125 (19), 2933-2936. doi: 10.1182/blood-2014-03-562660

Autophagy is required for stem cell mobilization by G-CSF

2015

Journal Article

Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells

Walter, Dagmar, Lier, Amelie, Geiselhart, Anja, Thalheimer, Frederic B., Huntscha, Sina, Sobotta, Mirko C., Moehrle, Bettina, Brocks, David, Bayindir, Irem, Kaschutnig, Paul, Muedder, Katja, Klein, Corinna, Jauch, Anna, Schroeder, Timm, Geiger, Hartmut, Dick, Tobias, Holland-Letz, Tim, Schmezer, Peter, Lane, Steven W., Rieger, Michael A., Essers, Marieke A. G., Williams, David A., Trumpp, Andreas and Milsom, Michael D. (2015). Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells. Nature, 520 (7548), 549-552. doi: 10.1038/nature14131

Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells

2015

Journal Article

A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction

Wallace, Daniel F., Secondes, Eriza S., Rishi, Gautam, Ostini, Lesa, McDonald, Cameron J., Lane, Steven W., Vu, Therese, Hooper, John D., Velasco, Gloria, Ramsay, Andrew J., Lopez-Otin, Carlos and Subramaniam, V. Nathan (2015). A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction. British Journal of Haematology, 168 (6), 891-901. doi: 10.1111/bjh.13225

A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction

2014

Journal Article

Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy

Bruedigam, C., Bagger, F.O., Heidel, F.H., Paine, Kuhn C., Guignes, S., Song, A., Austin, R., Vu, T., Lee, E., Riyat, S., Moore, A.S., Lock, R.B., Bullinger, L., Hill, G.R., Armstrong, S.A., Williams, D.A. and Lane, S.W. (2014). Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy. Cell Stem Cell, 15 (6), 775-790. doi: 10.1016/j.stem.2014.11.010

Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy

2014

Journal Article

Hit the spleen, JAK!

Lane, Steven W. and Mullally, Ann (2014). Hit the spleen, JAK!. Blood, 124 (19), 2898-2900. doi: 10.1182/blood-2014-09-600635

Hit the spleen, JAK!

2014

Journal Article

Modulating the stem cell niche for tissue regeneration

Lane, Steven W., Williams, David A. and Watt, Fiona M. (2014). Modulating the stem cell niche for tissue regeneration. Nature Biotechnology, 32 (8), 795-803. doi: 10.1038/nbt.2978

Modulating the stem cell niche for tissue regeneration

2014

Journal Article

Sorafenib priming may augment salvage chemotherapy in relapsed and refractory FLT3-ITD-positive acute myeloid leukemia

Cummins, K. D., Jane, S. M., Ninkovic, S., Bazargan, A., Filshie, R., Sutrave, G., Hertzberg, M., Scott, A., Lane, S., Yannakou, C. K., Ritchie, D., D'Rozario, J., Black, J., Bavishi, K. and Wei, A. (2014). Sorafenib priming may augment salvage chemotherapy in relapsed and refractory FLT3-ITD-positive acute myeloid leukemia. Blood Cancer Journal, 4 (e237) e237, 1-2. doi: 10.1038/bcj.2014.59

Sorafenib priming may augment salvage chemotherapy in relapsed and refractory FLT3-ITD-positive acute myeloid leukemia