|
2012 Journal Article mTOR complex 1 plays critical roles in hematopoiesis and pten-loss-evoked leukemogenesisKalaitzidis, Demetrios, Sykes, Stephen M., Wang, Zhu, Punt, Natalie, Tang, Yuefeng, Ragu, Christine, Sinha, Amit U., Lane, Steven W., Souza, Amanda L., Clish, Clary B., Anastasiou, Dimitrios, Gilliland, D. Gary, Scadden, David T., Guertin, David A. and Armstrong, Scott A. (2012). mTOR complex 1 plays critical roles in hematopoiesis and pten-loss-evoked leukemogenesis. Cell Stem Cell, 11 (3), 429-439. doi: 10.1016/j.stem.2012.06.009 |
|
2012 Journal Article Distinct roles for long-term hematopoietic stem cells and erythroid precursor cells in a murine model of Jak2V617F-mediated polycythemia veraMullally, Ann, Poveromo, Luke, Schneider, Rebekka K., Al-Shahrour, Fatima, Lane, Steven W. and Ebert, Benjamin L. (2012). Distinct roles for long-term hematopoietic stem cells and erythroid precursor cells in a murine model of Jak2V617F-mediated polycythemia vera. Blood, 120 (1), 166-172. doi: 10.1182/blood-2012-01-402396 |
|
2012 Journal Article Valproic acid combined with cytosine arabinoside in elderly patients with acute myeloid leukemia has in vitro but limited clinical activityLane, Steven, Gill, Devinder, McMillan, Nigel A. J., Saunders, Nicholas, Murphy, Rachel, Spurr, Terrence, Keane, Colm, Fan, Helen Mar and Mollee, Peter (2012). Valproic acid combined with cytosine arabinoside in elderly patients with acute myeloid leukemia has in vitro but limited clinical activity. Leukemia & Lymphoma, 53 (6), 1077-1083. doi: 10.3109/10428194.2011.642302 |
|
2012 Journal Article WT1 expression as a marker of minimal residual disease predicts outcome in acute myeloid leukemia when measured post-consolidationGray, James X., McMillen, Lyle, Mollee, Peter, Paul, Sanjoy, Lane, Steven, Bird, Robert, Gill, Devinder, Saal, Russell and Marlton, Paula (2012). WT1 expression as a marker of minimal residual disease predicts outcome in acute myeloid leukemia when measured post-consolidation. Leukemia Research, 36 (4), 453-458. doi: 10.1016/j.leukres.2011.09.005 |
|
2012 Journal Article Genetic and pharmacologic inhibition of beta-catenin targets imatinib-resistant leukemia stem cells in CMLHeidel, Florian H., Bullinger, Lars, Feng, Zhaohui, Wang, Zhu, Neff, Tobias A., Stein, Lauren, Kalaitzidis, Demetrios, Lane, Steve W. and Armstrong, Scott A. (2012). Genetic and pharmacologic inhibition of beta-catenin targets imatinib-resistant leukemia stem cells in CML. Cell Stem Cell, 10 (4), 412-424. doi: 10.1016/j.stem.2012.02.017 |
|
2012 Journal Article Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic developmentLane, Steven W., De Vita, Serena, Alexander, Kylie A., Karaman, Ruchan, Milsom, Michael D., Dorrance, Adrienne M., Purdon, Amy, Louis, Leeann, Bouxsein, Mary L. and Williams, David A. (2012). Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development. Blood, 119 (3), 736-744. doi: 10.1182/blood-2011-07-368753 |
|
2012 Journal Article Bad to the boneLane, Steven W. (2012). Bad to the bone. Blood, 119 (2), 323-325. doi: 10.1182/blood-2011-10-383901 |
|
2012 Journal Article Mechanism-Based Approach to the Economic Evaluation of Pharmaceuticals Pharmacokinetic/Pharmacodynamic/Pharmacoeconomic Analysis of Rituximab for Follicular LymphomaPink, Joshua, Lane, Steven and Hughes, Dyfrig A. (2012). Mechanism-Based Approach to the Economic Evaluation of Pharmaceuticals Pharmacokinetic/Pharmacodynamic/Pharmacoeconomic Analysis of Rituximab for Follicular Lymphoma. Pharmacoeconomics, 30 (5), 413-429. doi: 10.2165/11591540-000000000-00000 |
|
2012 Journal Article The population pharmacokinetics of R- and S-warfarin: effect of genetic and clinical factorsLane, Steven, Al-Zubiedi, Sameh, Hatch, Ellen, Matthews, Ivan, Jorgensen, Andrea L., Deloukas, Panos, Daly, Ann K., Park, B. Kevin, Aarons, Leon, Ogungbenro, Kayode, Kamali, Farhad, Hughes, Dyfrig and Pirmohamed, Munir (2012). The population pharmacokinetics of R- and S-warfarin: effect of genetic and clinical factors. British Journal of Clinical Pharmacology, 73 (1), 66-76. doi: 10.1111/j.1365-2125.2011.04051.x |
|
2011 Journal Article Degenerate RNA packaging signals in the genome of satellite tobacco necrosis virus: Implications for the assembly of a T = 1 capsidBunka, David H. J., Lane, Stephen W., Lane, Claire L., Dykeman, Eric C., Ford, Robert J., Barker, Amy M., Twarock, Reidun, Phillips, Simon E. V. and Stockley, Peter G. (2011). Degenerate RNA packaging signals in the genome of satellite tobacco necrosis virus: Implications for the assembly of a T = 1 capsid. Journal of Molecular Biology, 413 (1), 51-65. doi: 10.1016/j.jmb.2011.07.063 |
|
2011 Journal Article Construction and Crystal Structure of Recombinant STNV CapsidsLane, Stephen W., Dennis, Caitriona A., Lane, Claire L., Trinh, Chi H., Rizkallah, Pierre J., Stockley, Peter G. and Phillips, Simon E. V. (2011). Construction and Crystal Structure of Recombinant STNV Capsids. Journal of Molecular Biology, 413 (1), 41-50. doi: 10.1016/j.jmb.2011.07.062 |
|
2011 Journal Article AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemiasSykes, Stephen M., Lane, Steven W., Bullinger, Lars, Kalaitzidis, Demetrios, Yusuf, Rushdia, Saez, Borja, Ferraro, Francesca, Mercier, Francois, Singh, Harshabad, Brumme, Kristina M., Acharya, Sanket S., Schoell, Claudia, Tothova, Zuzana, Attar, Eyal C., Froehling, Stefan, DePinho, Ronald A., Armstrong, Scott A., Gilliland, D. Gary and Scadden, David T. (2011). AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias. Cell, 146 (5), 697-708. doi: 10.1016/j.cell.2011.07.032 |
|
2011 Journal Article Differential niche and Wnt requirements during acute myeloid leukemia progressionLane, Steven W., Wang, Yingzi J., Lo Celso, Cristina, Ragu, Christine, Bullinger, Lars, Sykes, Stephen M., Ferraro, Francesca, Shterental, Sebastian, Lin, Charles P., Gilliland, D. Gary, Scadden, David T., Armstrong, Scott A. and Williams, David A. (2011). Differential niche and Wnt requirements during acute myeloid leukemia progression. Blood, 118 (10), 2849-2856. doi: 10.1182/blood-2011-03-345165 |
|
2010 Journal Article Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemiaKharas, Michael G., Lengner, Christopher J., Al-Shahrour, Fatima, Bullinger, Lars, Ball, Brian, Zaidi, Samir, Morgan, Kelly, Tam, Winnie, Paktinat, Mahnaz, Okabe, Rachel, Gozo, Maricel, Einhorn, William, Lane, Steven W., Scholl, Claudia, Froehling, Stefan, Fleming, Mark, Ebert, Benjamin L., Gilliland, D. Gary, Jaenisch, Rudolf and Daley, George Q. (2010). Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia. Nature Medicine, 16 (8), 903-908. doi: 10.1038/nm.2187 |
|
2010 Journal Article CNS Relapse in Acute Promyeloctyic LeukemiaHousman, Elizabeth, Chang, Priscilla, Lane, Steven W., Blinder, Russell, Galinsky, Ilene, Kesari, Santosh, Ho, Vincent T., Stone, Richard M. and Mullally, Ann (2010). CNS Relapse in Acute Promyeloctyic Leukemia. Journal of Clinical Oncology, 28 (24), E409-E411. doi: 10.1200/JCO.2009.27.1577 |
|
2010 Journal Article Physiological Jak2V617F expression causes a lethal myeloproliferative neoplasm with differential effects on hematopoietis stem and progenitor cellsMullally, Ann, Lane, Steven W., Ball, Brian, Megerdichian, Christine, Okabe, Rachel, Al-Shahrour, Fatima, Paktinat, Mahnaz, Haydu, J. Erika, Housman, Elizabeth, Lord, Allegra M., Wernig, Gerlinde, Kharas, Michael G., Mercher, Thomas, Kutok, Jeffery L., Gilliland, D. Gary and Ebert, Benjamin L. (2010). Physiological Jak2V617F expression causes a lethal myeloproliferative neoplasm with differential effects on hematopoietis stem and progenitor cells. Cancer Cell, 17 (6), 584-596. doi: 10.1016/j.ccr.2010.05.015 |
|
2010 Journal Article The Apcmin mouse has altered hematopoietic stem cell function and provides a model for MPD/MDSLane, Steven W., Sykes, Stephen M., Al-Shahrour, Fatima, Shterental, Sebastian, Paktinat, Mahnaz, Lo Celso, Cristina, Jesneck, Jonathan L., Ebert, Benjamin L., Williams, David A. and Gilliland, D. Gary (2010). The Apcmin mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS. Blood, 115 (17), 3489-3497. doi: 10.1182/blood-2009-11-251728 |
|
2010 Journal Article Leukemia stem cellsLane, Steven W. and Gilliland, D. Gary (2010). Leukemia stem cells. Seminars in Cancer Biology, 20 (2), 71-76. doi: 10.1016/j.semcancer.2009.12.001 |
|
2009 Journal Article Characterization of the bone marrow immunofluorescence test in childhood autoimmune neutropeniaLane, S. W., Hassell, P., Kennedy, G. A., Fung, Y. L. and Williams, B. A. (2009). Characterization of the bone marrow immunofluorescence test in childhood autoimmune neutropenia. International Journal of Laboratory Hematology, 31 (5), 567-571. doi: 10.1111/j.1751-553X.2008.01084.x |
|
2009 Journal Article The leukemic stem cell niche: Current concepts and therapeutic opportunitiesLane, Steven W., Scadden, David T. and Gilliland, D. Gary (2009). The leukemic stem cell niche: Current concepts and therapeutic opportunities. Blood, 114 (6), 1150-1157. doi: 10.1182/blood-2009-01-202606 |
