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2015 Journal Article Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8<sup>+</sup> T cells that induce GVHD without antileukemic effectsGartlan, Kate H., Markey, Kate A., Varelias, Antiopi, Bunting, Mark D., Koyama, Motoko, Kuns, Rachel D., Raffelt, Neil C., Olver, Stuart D., Lineburg, Katie E., Cheong, Melody, Teal, Bianca E., Lor, Mary, Comerford, Iain, Teng, Michele W. L., Smyth, Mark J., McCluskey, James, Rossjohn, Jamie, Stockinger, Brigitta, Boyle, Glen M., Lane, Steven W., Clouston, Andrew D., McColl, Shaun R., MacDonald, Kelli P. A. and Hill, Geoffrey R. (2015). Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects. Blood, 126 (13), 1609-1620. doi: 10.1182/blood-2015-01-622662 |
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2015 Conference Publication SSB1 AND SSB2 SINGLE-STRANDED DNA BINDING PROTEINS ARE ESSENTIAL FOR HSC FUNCTIONVu, Therese, Shi, Wei, Lane, Steven and Khanna, Kum Kum (2015). SSB1 AND SSB2 SINGLE-STRANDED DNA BINDING PROTEINS ARE ESSENTIAL FOR HSC FUNCTION. 44th Annual Scientific Meeting of the International-Society-for-Experimental-Hematology (ISEH), Kyoto Japan, Sep 17-19, 2015. NEW YORK: ELSEVIER SCIENCE INC. doi: 10.1016/j.exphem.2015.06.274 |
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2015 Journal Article Ssb2/Nabp1 is dispensable for thymic maturation, male fertility, and DNA repair in miceBoucher, Didier, Vu, Therese, Bain, Amanda L., Tagliaro-Jahns, Marina, Shi, Wei, Lane, Steven W. and Khanna, Kum Kum (2015). Ssb2/Nabp1 is dispensable for thymic maturation, male fertility, and DNA repair in mice. FASEB Journal, 29 (8), 3326-3334. doi: 10.1096/fj.14-269944 |
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2015 Journal Article EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia.Charmsaz, Sara, Beckett, Kirrilee, Smith, Fiona M., Bruedigam, Claudia, Moore, Andrew S., Al-Ejeh, Fares, Lane, Steven W. and Boyd, Andrew W. (2015). EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia.. PLoS One, 10 (6) e0130692, e0130692-e0130692. doi: 10.1371/journal.pone.0130692 |
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2015 Journal Article Autophagy is required for stem cell mobilization by G-CSFLeveque-El Mouttie, Lucie, Vu, Therese, Lineburg, Katie E., Kuns, Rachel D., Bagger, Frederik O., Teal, Bianca E., Lor, Mary, Boyle, Glen M., Bruedigam, Claudia, Mintern, Justine D., Hill, Geoffrey R., MacDonald, Kelli P. A. and Lane, Steven W. (2015). Autophagy is required for stem cell mobilization by G-CSF. Blood, 125 (19), 2933-2936. doi: 10.1182/blood-2014-03-562660 |
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2015 Conference Publication The adaptor protein ASC controls transplantation outcomes independently of the inflammasomeCheong, Melody, Gartlan, Kate, Tey, Siok-Keen, Kuns, Rachel, Lor, Mary, Lineburg, Katie, Tea, Bianca, Shi, Wei, Raju, Jyothy, Zhang, Ping, Varelias, Antiopi, Leveque-El Mouttie, Lucie, Olver, Stuart, Bunting, Mark, Lane, Steven, Boyle, Glen, Ting, Jenny, Schroder, Kate, Engwerda, Christian, Khanna, Kum Kum, Smyth, Mark, MacDonald, Kelli, Koyama, Motoko and Hill, Geoffrey (2015). The adaptor protein ASC controls transplantation outcomes independently of the inflammasome. Annual Meeting of the American-Association-of-Immunologists (IMMUNOLOGY), New Orleans La, May 08-12, 2015. BETHESDA: AMER ASSOC IMMUNOLOGISTS. |
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2015 Journal Article Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cellsWalter, Dagmar, Lier, Amelie, Geiselhart, Anja, Thalheimer, Frederic B., Huntscha, Sina, Sobotta, Mirko C., Moehrle, Bettina, Brocks, David, Bayindir, Irem, Kaschutnig, Paul, Muedder, Katja, Klein, Corinna, Jauch, Anna, Schroeder, Timm, Geiger, Hartmut, Dick, Tobias, Holland-Letz, Tim, Schmezer, Peter, Lane, Steven W., Rieger, Michael A., Essers, Marieke A. G., Williams, David A., Trumpp, Andreas and Milsom, Michael D. (2015). Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells. Nature, 520 (7548), 549-552. doi: 10.1038/nature14131 |
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2015 Journal Article Offending outcomes of a mental health youth diversion pilot scheme in EnglandHaines, Alina, Lane, Steven, Mcguire, James, Perkins, Elizabeth and Whittington, Richard (2015). Offending outcomes of a mental health youth diversion pilot scheme in England. Criminal Behaviour and Mental Health, 25 (2), 126-140. doi: 10.1002/cbm.1916 |
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2015 Journal Article A critical role for murine transferrin receptor 2 in erythropoiesis during iron restrictionWallace, Daniel F., Secondes, Eriza S., Rishi, Gautam, Ostini, Lesa, McDonald, Cameron J., Lane, Steven W., Vu, Therese, Hooper, John D., Velasco, Gloria, Ramsay, Andrew J., Lopez-Otin, Carlos and Subramaniam, V. Nathan (2015). A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction. British Journal of Haematology, 168 (6), 891-901. doi: 10.1111/bjh.13225 |
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2014 Journal Article A Review of A Priori Regression Models for Warfarin Maintenance Dose PredictionFrancis, Ben, Lane, Steven, Pirmohamed, Munir and Jorgensen, Andrea (2014). A Review of A Priori Regression Models for Warfarin Maintenance Dose Prediction. Plos One, 9 (12) e114896. doi: 10.1371/journal.pone.0114896 |
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2014 Journal Article Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapyBruedigam, C., Bagger, F.O., Heidel, F.H., Paine, Kuhn C., Guignes, S., Song, A., Austin, R., Vu, T., Lee, E., Riyat, S., Moore, A.S., Lock, R.B., Bullinger, L., Hill, G.R., Armstrong, S.A., Williams, D.A. and Lane, S.W. (2014). Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy. Cell Stem Cell, 15 (6), 775-790. doi: 10.1016/j.stem.2014.11.010 |
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2014 Journal Article Hit the spleen, JAK!Lane, Steven W. and Mullally, Ann (2014). Hit the spleen, JAK!. Blood, 124 (19), 2898-2900. doi: 10.1182/blood-2014-09-600635 |
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2014 Journal Article Modulating the stem cell niche for tissue regenerationLane, Steven W., Williams, David A. and Watt, Fiona M. (2014). Modulating the stem cell niche for tissue regeneration. Nature Biotechnology, 32 (8), 795-803. doi: 10.1038/nbt.2978 |
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2014 Journal Article Sorafenib priming may augment salvage chemotherapy in relapsed and refractory FLT3-ITD-positive acute myeloid leukemiaCummins, K. D., Jane, S. M., Ninkovic, S., Bazargan, A., Filshie, R., Sutrave, G., Hertzberg, M., Scott, A., Lane, S., Yannakou, C. K., Ritchie, D., D'Rozario, J., Black, J., Bavishi, K. and Wei, A. (2014). Sorafenib priming may augment salvage chemotherapy in relapsed and refractory FLT3-ITD-positive acute myeloid leukemia. Blood Cancer Journal, 4 (e237) e237, 1-2. doi: 10.1038/bcj.2014.59 |
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2014 Journal Article Cost-Effectiveness of Pharmacogenetics-Guided Warfarin Therapy vs. Alternative Anticoagulation in Atrial FibrillationPink, J., Pirmohamed, M., Lane, S. and Hughes, D. A. (2014). Cost-Effectiveness of Pharmacogenetics-Guided Warfarin Therapy vs. Alternative Anticoagulation in Atrial Fibrillation. Clinical Pharmacology & Therapeutics, 95 (2), 199-207. doi: 10.1038/clpt.2013.190 |
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2014 Journal Article The Apcmin mouse has altered hematopoietic stem cell function and provides a model for MPD/MDSLane, S. W., Sykes, S. M., Al-Shahrour, F., Shterental, S., Paktinat, M., Lo Celso, C., Jesneck, J. L., Ebert, B. L., Williams, D. A. and Gilliland, D. Gary (2014). The Apcmin mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS. Blood, 123 (2), 301-301. doi: 10.1182/blood-2013-11-540047 |
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2014 Conference Publication Investigation of mice deficient in matriptase-2, Hfe and transferrin receptor 2 reveals a novel non-hepatic role for Tfr2 in erythropoiesisWallace, D. F., Secondes, E. S., Rishi, G., Ostini, L., Mcdonald, C. J., Lane, S. W., Hooper, J. D., Lopez-Otin, C. and Subramaniam, V. N. (2014). Investigation of mice deficient in matriptase-2, Hfe and transferrin receptor 2 reveals a novel non-hepatic role for Tfr2 in erythropoiesis. Australian Gastroenterology Week 2014, Broadbeach, Australia, 22-24 October 2014. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12736_6 |
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2013 Journal Article The cell fate determinant Llgl1 influences HSC fitness and prognosis in AMLHeidel, Florian H., Bullinger, Lars, Arreba-Tutusaus, Patricia, Wang, Zhu, Gaebel, Julia, Hirt, Carsten, Niederwieser, Dietger, Lane, Steven W., Doehner, Konstanze, Vasioukhin, Valera, Fischer, Thomas and Armstrong, Scott A. (2013). The cell fate determinant Llgl1 influences HSC fitness and prognosis in AML. Journal of Experimental Medicine, 210 (1), 15-22. doi: 10.1084/jem.20120596 |
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2013 Journal Article Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivoZhang, Ping, Tey, Siok-Keen, Koyama, Motoko, Kuns, Rachel D., Olver, Stuart D., Lineburg, Katie E., Lor, Mary, Teal, Bianca E., Raffelt, Neil C., Raju, Jyothy, Leveque, Lucie, Markey, Kate A., Varelias, Antiopi, Clouston, Andrew D., Lane, Steven W., Macdonald, Kelli P. A. and Hill, Geoffrey R. (2013). Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo. Journal of Immunology, 191 (10), 5291-5303. doi: 10.4049/jimmunol.1301181 |
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2013 Journal Article Deciphering hematopoietic stem cells in their niches: a critical appraisal of genetic models, lineage tracing, and imaging strategiesJoseph, Chacko, Quach, Julie M., Walkley, Carl R., Lane, Steven W., Lo Celso, Cristina and Purton, Louise E. (2013). Deciphering hematopoietic stem cells in their niches: a critical appraisal of genetic models, lineage tracing, and imaging strategies. Cell Stem Cell, 13 (5), 520-533. doi: 10.1016/j.stem.2013.10.010 |
