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2023 Journal Article A mixed method, phase 2 clinical evaluation of a novel device to treat postpartum haemorrhageWeeks, Andrew D., Cunningham, Caroline, Taylor, Wendy, Rosala-Hallas, Anna, Watt, Peter, Bryning, Lucy, Ezeofor, Victory, Cregan, Liz, Hayden, Emma, Lambert, Dot, Bedwell, Carol, Lane, Steven, Fisher, Tony, Edwards, Rhiannon T. and Lavender, Tina (2023). A mixed method, phase 2 clinical evaluation of a novel device to treat postpartum haemorrhage. European Journal of Obstetrics and Gynecology and Reproductive Biology, 283, 142-148. doi: 10.1016/j.ejogrb.2023.01.018 |
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2023 Journal Article Cre recombinase expression cooperates with homozygous FLT3 internal tandem duplication knockin mouse model to induce acute myeloid leukemiaStraube, Jasmin, Eifert, Theresa, Vu, Therese, Janardhanan, Yashaswini, Haldar, Rohit, von Eyss, Björn, Cooper, Leanne, Bruedigam, Claudia, Ling, Victoria Y., Cooper, Emily, Patch, Ann-Marie, Bullinger, Lars, Schnoeder, Tina M., Bywater, Megan, Heidel, Florian H. and Lane, Steven W. (2023). Cre recombinase expression cooperates with homozygous FLT3 internal tandem duplication knockin mouse model to induce acute myeloid leukemia. Leukemia, 37 (4), 741-750. doi: 10.1038/s41375-023-01832-0 |
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2023 Journal Article Real world molecular characterisation and clonal evolution of acute myeloid leukaemia reveals therapeutic opportunities and challengesNelles, Ricky, Seymour, Louise, Richmond, Joshua and Lane, Steven (2023). Real world molecular characterisation and clonal evolution of acute myeloid leukaemia reveals therapeutic opportunities and challenges. Pathology, 55 (1), 64-70. doi: 10.1016/j.pathol.2022.07.019 |
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2023 Journal Article t(15;17) in acute promyelocytic leukemiaLing, Victoria Y. and Lane, Steven W. (2023). t(15;17) in acute promyelocytic leukemia. Haematologica, 108 (2), 295-296. doi: 10.3324/haematol.2022.282577 |
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2023 Conference Publication Minocycline and/or omega-3 fatty acids added to treatment as usual for individuals with at risk mental states. A large multicenter double blind RCTQurashi, I., Chaudhry, B., Khoso, B. A., Husain, M. O., Hafeez, D., Kiran, T., Lane, S., Naqvi, A. H., Minhas, A. F., Nizami, T. A., Razzaque, B., Bokhari, Q. S., Yung, R. A., Deakin, B. and Husain, N. (2023). Minocycline and/or omega-3 fatty acids added to treatment as usual for individuals with at risk mental states. A large multicenter double blind RCT. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD. doi: 10.1016/j.jpsychores.2023.111238 |
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2023 Conference Publication Immunoproteasome Function Maintains Oncogenic Gene Expression In Kmt2a-complex Driven LeukemiaHeidel, Florian, Tubio-Santamaria, Nuria, Jayavelu, Ashok Kumar, Schnoeder, Tina, Eifert, Theresa, Hsu, Chen-Jen, Perner, Florian, Zhang, Qirui, Wenge, Daniela, Hansen, Fynn, Jyotsana, Nidhi, Lane, Steven, von Eyss, Björn, Deshpande, Aniruddha, Kühn, Michael, Schwaller, Jürg, Ebstein, Frederic, Krüger, Elke, Hochhaus, Andreas, Heuser, Michael, Ori, alessandro, Mann, Matthias and Armstrong, Scott (2023). Immunoproteasome Function Maintains Oncogenic Gene Expression In Kmt2a-complex Driven Leukemia. 2023 Annual Scientific Meeting of the ISEH – International Society for Experimental Hematology, New York, NY United States, 17-20 August 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.exphem.2023.06.049 |
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2023 Journal Article Targeting cell cycle and apoptosis to overcome chemotherapy resistance in acute myeloid leukemiaLing, Victoria Y., Straube, Jasmin, Godfrey, William, Haldar, Rohit, Janardhanan, Yashaswini, Cooper, Leanne, Bruedigam, Claudia, Cooper, Emily, Tavakoli Shirazi, Paniz, Jacquelin, Sebastien, Tey, Siok-Keen, Baell, Jonathan, Huang, Fei, Jin, Jianwen, Zhao, Yichao, Bullinger, Lars, Bywater, Megan J. and Lane, Steven W. (2023). Targeting cell cycle and apoptosis to overcome chemotherapy resistance in acute myeloid leukemia. Leukemia, 37 (1), 143-153. doi: 10.1038/s41375-022-01755-2 |
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2022 Journal Article The importance of pore-forming toxins in multiple organ injury and dysfunctionAbrams, Simon T. T., Wang, Lijun, Yong, Jun, Yu, Qian, Du, Min, Alhamdi, Yasir, Cheng, Zhenxing, Dart, Caroline, Lane, Steven, Yu, Weiping, Toh, Cheng-Hock and Wang, Guozheng (2022). The importance of pore-forming toxins in multiple organ injury and dysfunction. Biomedicines, 10 (12) 3256, 1-15. doi: 10.3390/biomedicines10123256 |
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2022 Conference Publication Early and Deep Molecular Responses Achieved with Frontline Asciminib in Chronic Phase CML - Interim Results from ALLG CML13 Ascend-CMLYeung, David T., Shanmuganathan, Naranie, Reynolds, John, Branford, Susan, Walia, Mannu, Yong, Agnes S.M., Shortt, Jake, Burbury, Kate, Viiala, Nicholas, Cunningham, Ilona, Ross, David M., Harrup, Rosemary, Wright, Matthew, Forsyth, Cecily, D'Souza, Alwyn Bernard, Filshie, Robin J., Browett, Peter J., Lane, Steven W., Grove, Carolyn, Grigg, Andrew and Hughes, Timothy (2022). Early and Deep Molecular Responses Achieved with Frontline Asciminib in Chronic Phase CML - Interim Results from ALLG CML13 Ascend-CML. 64th ASH Annual Meeting, New Orleans, LA United States, 10-13 December 2022. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2022-157244 |
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2022 Conference Publication Loss of Cell Fate Determinant LLGL1 Impairs Leukemia Development in Acute Myeloid LeukemiaEifert, Theresa, Schnoeder, Tina M. M., Hsu, Chen-Jen, Becker, Alicia L., Zhang, Qirui, Mohr, Juliane, Frey, Stephanie, Scholl, Sebastian, Bullinger, Lars, Lane, Steven W. and Heidel, Florian H. (2022). Loss of Cell Fate Determinant LLGL1 Impairs Leukemia Development in Acute Myeloid Leukemia. 64th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), New Orleans La, Dec 10-13, 2022. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2022-157247 |
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2022 Conference Publication Comparative Analysis of Genome-Scale Gene Regulatory Networks in Human Hematopoietic Stem and Myeloid Progenitor FractionsSubramanian, Shruthi, Thoms, Julie A., Huang, Yizhou, Jacquelin, Sebastien, Shen, Sylvie, Song, Emma, Joshi, Swapna, Brownlee, Chris, Woll, Petter S., Fajardo, Diego Chacon, Beck, Dominik, Curtis, David J., Yehson, Kenneth, Antonenas, Vicki, O' Brien, Tracey, Trickett, Annette, Powell, Jason, Pitson, Stuart M., Gandhi, Maher K., Cornejo, Paola, Wong, Emily, Lane, Steven W., Gottgens, Bertie, Rokny, Hamid Alinejad, Wong, Jason W. H. and Pimanda, John E. (2022). Comparative Analysis of Genome-Scale Gene Regulatory Networks in Human Hematopoietic Stem and Myeloid Progenitor Fractions. 64th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), New Orleans La, Dec 10-13, 2022. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2022-165620 |
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2022 Conference Publication Imetelstat-Mediated Alterations in Lipid Metabolism to Induce Ferroptosis As Therapeutic Strategy for Acute Myeloid LeukemiaBruedigam, Claudia, Porter, Amy H., Song, Axia, Vroeg in de Wei, Gerjanne, Stoll, Thomas, Straube, Jasmin, Cooper, Leanne T., Cheng, Guidan, Kahl, Vivian F.S., Sobinoff, Alexander, Ling, Victoria Y., Jebaraj, Billy Michael Chelliah, Bray, Laura J., Bullinger, Lars, Heidel, Florian H., Kennedy, Glen A., Hill, Michelle M., Pickett, Hilda, Abdel-Wahab, Omar, Hartel, Gunter and Lane, Steven W. (2022). Imetelstat-Mediated Alterations in Lipid Metabolism to Induce Ferroptosis As Therapeutic Strategy for Acute Myeloid Leukemia. 64th ASH Annual Meeting, New Orleans, LA United States, 10-13 December 2022. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2022-168166 |
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2022 Conference Publication A Phase 2 Study of the LSD1 Inhibitor Bomedemstat (IMG-7289) for the Treatment of Essential Thrombocythemia (ET)Gill, Harinder, Palandri, Francesca, Ross, David M., Cochrane, Tara, Tate, Courtney, Lane, Steven W., Larsen, Stephen R., Gerds, Aaron T., Halpern, Anna B., Shortt, Jake, Rossetti, James M., Pettit, Kristen M., Liang, James, Mead, Adam J., Marchetti, Monia, Vannucchi, Alessandro M., Wilson, Andrew J., Goethert, Joachim R., Hanna, Merit, Passamonti, Francesco, Stevenson, William S., Harrison, Claire, Talpaz, Moshe, Vianelli, Nicola and Rienhoff, Hugh Young (2022). A Phase 2 Study of the LSD1 Inhibitor Bomedemstat (IMG-7289) for the Treatment of Essential Thrombocythemia (ET). 64th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), New Orleans La, Dec 10-13, 2022. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2022-159047 |
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2022 Journal Article The role of anal manometry in the follow-up of women with obstetric anal sphincter injuries (OASI)Badri, Hawra, Fowler, Gillian and Lane, Steven (2022). The role of anal manometry in the follow-up of women with obstetric anal sphincter injuries (OASI). International Urogynecology Journal, 34 (2), 399-404. doi: 10.1007/s00192-022-05380-6 |
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2022 Journal Article Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunityMinnie, Simone A., Waltner, Olivia G., Ensbey, Kathleen S., Nemychenkov, Nicole S., Schmidt, Christine R., Bhise, Shruti S., Legg, Samuel R. W., Campoy, Gabriela, Samson, Luke D., Kuns, Rachel D., Zhou, Ting, Huck, John D., Vuckovic, Slavica, Zamora, Danniel, Yeh, Albert, Spencer, Andrew, Koyama, Motoko, Markey, Kate A., Lane, Steven W., Boeckh, Michael, Ring, Aaron M., Furlan, Scott N. and Hill, Geoffrey R. (2022). Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity. Science Immunology, 7 (76) eabo3420, 1-18. doi: 10.1126/sciimmunol.abo3420 |
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2022 Journal Article Parents' experiences and perceptions of the acceptability of a whole-hospital, pro-active electronic pediatric early warning system (the DETECT study): a qualitative interview studySaron, Holly, Carter, Bernie, Siner, Sarah, Preston, Jennifer, Peak, Matthew, Mehta, Fulya, Lane, Steven, Lambert, Caroline, Jones, Dawn, Hughes, Hannah, Harris, Jane, Evans, Leah, Dee, Sarah, Eyton-Chong, Chin-Kien, Carrol, Enitan D. and Sefton, Gerri (2022). Parents' experiences and perceptions of the acceptability of a whole-hospital, pro-active electronic pediatric early warning system (the DETECT study): a qualitative interview study. Frontiers in Pediatrics, 10 954738. doi: 10.3389/fped.2022.954738 |
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2022 Journal Article Paving the way to improve therapy for Myeloproliferative NeoplasmsBywater, Megan and Lane, Steven W. (2022). Paving the way to improve therapy for Myeloproliferative Neoplasms. Nature Communications, 13 (1) 5025, 1-3. doi: 10.1038/s41467-022-32694-2 |
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2022 Journal Article Epigenetic activation of Plasmacytoid DCs drives IFNAR-dependent therapeutic differentiation of AMLSalmon, Jessica M., Todorovski, Izabela, Stanley, Kym L., Bruedigam, Claudia, Kearney, Conor J., Martelotto, Luciano G., Rossello, Fernando, Semple, Timothy, Arnau, Gisela Mir, Zethoven, Magnus, Bots, Michael, Bjelosevic, Stefan, Cluse, Leonie A., Fraser, Peter J., Litalien, Veronique, Vidacs, Eva, McArthur, Kate, Matthews, Antony Y., Gressier, Elise, De Weerd, Nicole A., Lichte, Jens, Kelly, Madison J., Hogg, Simon J., Hertzog, Paul J., Kats, Lev M., Vervoort, Stephin J., De Carvalho, Daniel D., Scheu, Stefanie, Bedoui, Sammy ... Johnstone, Ricky W. (2022). Epigenetic activation of Plasmacytoid DCs drives IFNAR-dependent therapeutic differentiation of AML. Cancer Discovery, 12 (6), 1560-1579. doi: 10.1158/2159-8290.CD-20-1145 |
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2022 Journal Article Panel-based gene testing in myelodysplastic/myeloproliferative neoplasm overlap syndromes: Australasian Leukaemia and Lymphoma Group (ALLG) consensus statementEnjeti, Anoop K., Agarwal, Rishu, Blombery, Piers, Chee, Lynette, Chua, Chong Chyn, Grigg, Andrew, Hamad, Nada, Iland, Harry, Lane, Steven, Perkins, Andrew, Singhal, Deepak, Tate, Courtney, Tiong, Ing Soo and Ross, David M. (2022). Panel-based gene testing in myelodysplastic/myeloproliferative neoplasm overlap syndromes: Australasian Leukaemia and Lymphoma Group (ALLG) consensus statement. Pathology, 54 (4), 389-398. doi: 10.1016/j.pathol.2022.03.002 |
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2022 Journal Article Vitamin D, vitamin D-binding protein, free vitamin D and COVID-19 mortality in hospitalized patientsSubramanian, Sreedhar, Rhodes, Jonathan M., Taylor, Joseph M., Milan, Anna M., Lane, Steven, Hewison, Martin, Chun, Rene F., Jorgensen, Andrea, Richardson, Paul, Nitchingham, Darshan, Aslan, Joseph, Shah, Maya, Chandrasekar, Coonoor R., Wood, Amanda, Beadsworth, Mike and Pirmohamed, Munir (2022). Vitamin D, vitamin D-binding protein, free vitamin D and COVID-19 mortality in hospitalized patients. American Journal of Clinical Nutrition, 115 (5), 1367-1377. doi: 10.1093/ajcn/nqac027 |
