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2022 Conference Publication Comparative Analysis of Genome-Scale Gene Regulatory Networks in Human Hematopoietic Stem and Myeloid Progenitor FractionsSubramanian, Shruthi, Thoms, Julie A., Huang, Yizhou, Jacquelin, Sebastien, Shen, Sylvie, Song, Emma, Joshi, Swapna, Brownlee, Chris, Woll, Petter S., Fajardo, Diego Chacon, Beck, Dominik, Curtis, David J., Yehson, Kenneth, Antonenas, Vicki, O' Brien, Tracey, Trickett, Annette, Powell, Jason, Pitson, Stuart M., Gandhi, Maher K., Cornejo, Paola, Wong, Emily, Lane, Steven W., Gottgens, Bertie, Rokny, Hamid Alinejad, Wong, Jason W. H. and Pimanda, John E. (2022). Comparative Analysis of Genome-Scale Gene Regulatory Networks in Human Hematopoietic Stem and Myeloid Progenitor Fractions. 64th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), New Orleans La, Dec 10-13, 2022. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2022-165620 |
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2022 Conference Publication Imetelstat-Mediated Alterations in Lipid Metabolism to Induce Ferroptosis As Therapeutic Strategy for Acute Myeloid LeukemiaBruedigam, Claudia, Porter, Amy H., Song, Axia, Vroeg in de Wei, Gerjanne, Stoll, Thomas, Straube, Jasmin, Cooper, Leanne T., Cheng, Guidan, Kahl, Vivian F.S., Sobinoff, Alexander, Ling, Victoria Y., Jebaraj, Billy Michael Chelliah, Bray, Laura J., Bullinger, Lars, Heidel, Florian H., Kennedy, Glen A., Hill, Michelle M., Pickett, Hilda, Abdel-Wahab, Omar, Hartel, Gunter and Lane, Steven W. (2022). Imetelstat-Mediated Alterations in Lipid Metabolism to Induce Ferroptosis As Therapeutic Strategy for Acute Myeloid Leukemia. 64th ASH Annual Meeting, New Orleans, LA United States, 10-13 December 2022. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2022-168166 |
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2022 Conference Publication A Phase 2 Study of the LSD1 Inhibitor Bomedemstat (IMG-7289) for the Treatment of Essential Thrombocythemia (ET)Gill, Harinder, Palandri, Francesca, Ross, David M., Cochrane, Tara, Tate, Courtney, Lane, Steven W., Larsen, Stephen R., Gerds, Aaron T., Halpern, Anna B., Shortt, Jake, Rossetti, James M., Pettit, Kristen M., Liang, James, Mead, Adam J., Marchetti, Monia, Vannucchi, Alessandro M., Wilson, Andrew J., Goethert, Joachim R., Hanna, Merit, Passamonti, Francesco, Stevenson, William S., Harrison, Claire, Talpaz, Moshe, Vianelli, Nicola and Rienhoff, Hugh Young (2022). A Phase 2 Study of the LSD1 Inhibitor Bomedemstat (IMG-7289) for the Treatment of Essential Thrombocythemia (ET). 64th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), New Orleans La, Dec 10-13, 2022. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2022-159047 |
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2022 Journal Article The role of anal manometry in the follow-up of women with obstetric anal sphincter injuries (OASI)Badri, Hawra, Fowler, Gillian and Lane, Steven (2022). The role of anal manometry in the follow-up of women with obstetric anal sphincter injuries (OASI). International Urogynecology Journal, 34 (2), 399-404. doi: 10.1007/s00192-022-05380-6 |
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2022 Journal Article Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunityMinnie, Simone A., Waltner, Olivia G., Ensbey, Kathleen S., Nemychenkov, Nicole S., Schmidt, Christine R., Bhise, Shruti S., Legg, Samuel R. W., Campoy, Gabriela, Samson, Luke D., Kuns, Rachel D., Zhou, Ting, Huck, John D., Vuckovic, Slavica, Zamora, Danniel, Yeh, Albert, Spencer, Andrew, Koyama, Motoko, Markey, Kate A., Lane, Steven W., Boeckh, Michael, Ring, Aaron M., Furlan, Scott N. and Hill, Geoffrey R. (2022). Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity. Science Immunology, 7 (76) eabo3420, 1-18. doi: 10.1126/sciimmunol.abo3420 |
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2022 Journal Article Parents' experiences and perceptions of the acceptability of a whole-hospital, pro-active electronic pediatric early warning system (the DETECT study): a qualitative interview studySaron, Holly, Carter, Bernie, Siner, Sarah, Preston, Jennifer, Peak, Matthew, Mehta, Fulya, Lane, Steven, Lambert, Caroline, Jones, Dawn, Hughes, Hannah, Harris, Jane, Evans, Leah, Dee, Sarah, Eyton-Chong, Chin-Kien, Carrol, Enitan D. and Sefton, Gerri (2022). Parents' experiences and perceptions of the acceptability of a whole-hospital, pro-active electronic pediatric early warning system (the DETECT study): a qualitative interview study. Frontiers in Pediatrics, 10 954738. doi: 10.3389/fped.2022.954738 |
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2022 Journal Article Paving the way to improve therapy for Myeloproliferative NeoplasmsBywater, Megan and Lane, Steven W. (2022). Paving the way to improve therapy for Myeloproliferative Neoplasms. Nature Communications, 13 (1) 5025. doi: 10.1038/s41467-022-32694-2 |
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2022 Journal Article Epigenetic activation of Plasmacytoid DCs drives IFNAR-dependent therapeutic differentiation of AMLSalmon, Jessica M., Todorovski, Izabela, Stanley, Kym L., Bruedigam, Claudia, Kearney, Conor J., Martelotto, Luciano G., Rossello, Fernando, Semple, Timothy, Arnau, Gisela Mir, Zethoven, Magnus, Bots, Michael, Bjelosevic, Stefan, Cluse, Leonie A., Fraser, Peter J., Litalien, Veronique, Vidacs, Eva, McArthur, Kate, Matthews, Antony Y., Gressier, Elise, De Weerd, Nicole A., Lichte, Jens, Kelly, Madison J., Hogg, Simon J., Hertzog, Paul J., Kats, Lev M., Vervoort, Stephin J., De Carvalho, Daniel D., Scheu, Stefanie, Bedoui, Sammy ... Johnstone, Ricky W. (2022). Epigenetic activation of Plasmacytoid DCs drives IFNAR-dependent therapeutic differentiation of AML. Cancer Discovery, 12 (6), 1560-1579. doi: 10.1158/2159-8290.CD-20-1145 |
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2022 Journal Article Panel-based gene testing in myelodysplastic/myeloproliferative neoplasm overlap syndromes: Australasian Leukaemia and Lymphoma Group (ALLG) consensus statementEnjeti, Anoop K., Agarwal, Rishu, Blombery, Piers, Chee, Lynette, Chua, Chong Chyn, Grigg, Andrew, Hamad, Nada, Iland, Harry, Lane, Steven, Perkins, Andrew, Singhal, Deepak, Tate, Courtney, Tiong, Ing Soo and Ross, David M. (2022). Panel-based gene testing in myelodysplastic/myeloproliferative neoplasm overlap syndromes: Australasian Leukaemia and Lymphoma Group (ALLG) consensus statement. Pathology, 54 (4), 389-398. doi: 10.1016/j.pathol.2022.03.002 |
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2022 Journal Article Vitamin D, vitamin D-binding protein, free vitamin D and COVID-19 mortality in hospitalized patientsSubramanian, Sreedhar, Rhodes, Jonathan M., Taylor, Joseph M., Milan, Anna M., Lane, Steven, Hewison, Martin, Chun, Rene F., Jorgensen, Andrea, Richardson, Paul, Nitchingham, Darshan, Aslan, Joseph, Shah, Maya, Chandrasekar, Coonoor R., Wood, Amanda, Beadsworth, Mike and Pirmohamed, Munir (2022). Vitamin D, vitamin D-binding protein, free vitamin D and COVID-19 mortality in hospitalized patients. American Journal of Clinical Nutrition, 115 (5), 1367-1377. doi: 10.1093/ajcn/nqac027 |
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2022 Journal Article Better the cure you know: why patients with AML ≥60 years of age should be offered early allogeneic stem cell transplantationTey, Siok-Keen and Lane, Steven W (2022). Better the cure you know: why patients with AML ≥60 years of age should be offered early allogeneic stem cell transplantation. Blood Advances, 6 (5), 1619-1622. doi: 10.1182/bloodadvances.2021004829 |
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2022 Journal Article PLCG1 is required for AML1-ETO leukemia stem cell self-renewalSchnoeder, Tina M., Schwarzer, Adrian, Jayavelu, Ashok Kumar, Hsu, Chen-Jen, Kirkpatrick, Joanna, Döhner, Konstanze, Perner, Florian, Eifert, Theresa, Huber, Nicolas, Arreba-Tutusaus, Patricia, Dolnik, Anna, Assi, Salam A, Nafria, Monica, Jiang, Lu, Dai, Yu-Ting, Chen, Zhu, Chen, Sai-Juan, Kellaway, Sophie G., Ptasinska, Anetta, Ng, Elizabeth S., Stanley, Edouard G., Elefanty, Andrew G., Buschbeck, Marcus, Bierhoff, Holger, Brodt, Steffen, Matziolis, Georg, Fischer, Klaus-Dieter, Hochhaus, Andreas, Chen, Chun-Wei ... Heidel, Florian (2022). PLCG1 is required for AML1-ETO leukemia stem cell self-renewal. Blood, 139 (7), 1080-1097. doi: 10.1182/blood.2021012778 |
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2022 Journal Article Reduction of NETosis by targeting CXCR1/2 reduces thrombosis, lung injury, and mortality in experimental human and murine sepsisAlsabani, Mohmad, Abrams, Simon T., Cheng, Zhenxing, Morton, Ben, Lane, Steven, Alosaimi, Samar, Yu, Weiping, Wang, Guozheng and Toh, Cheng-Hock (2022). Reduction of NETosis by targeting CXCR1/2 reduces thrombosis, lung injury, and mortality in experimental human and murine sepsis. British Journal of Anaesthesia, 128 (2), 283-293. doi: 10.1016/j.bja.2021.10.039 |
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2021 Conference Publication A Phase 2 Study of the LSD1 Inhibitor Img-7289 (bomedemstat) for the Treatment of Essential Thrombocythemia (ET)Palandri, Francesca, Vianelli, Nicola, Ross, David M., Cochrane, Tara, Lane, Steven W., Larsen, Stephen R., Gerds, Aaron T., Halpern, Anna B., Shortt, Jake, Rossetti, James M., Pettit, Kristen M., Jones, Amber, Peppe, Jennifer, Natsoulis, Georges, Navarro, Willis, Hong, Wan-Jen, Stevenson, William S., Harrison, Claire N., Talpaz, Moshe and Rienhoff, Hugh Young (2021). A Phase 2 Study of the LSD1 Inhibitor Img-7289 (bomedemstat) for the Treatment of Essential Thrombocythemia (ET). 63rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta Ga, Dec 11-14, 2021. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2021-148210 |
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2021 Conference Publication Targeting Control of Cell Cycle Enhances the Activity of Conventional Chemotherapy in Chemotherapy-Resistant Acute Myeloid LeukemiaLing, Victoria Y., Jacquelin, Sebastien, Straube, Jasmin, Haldar, Rohit, Janardhanan, Yashaswini, Cooper, Leanne T., Bruedigam, Claudia, Cooper, Emily, Godfrey, William, Tey, Siok-Keen, Bullinger, Lars, Herold, Marco J., Baell, Jonathan, Bywater, Megan and Lane, Steven W. (2021). Targeting Control of Cell Cycle Enhances the Activity of Conventional Chemotherapy in Chemotherapy-Resistant Acute Myeloid Leukemia. 63rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta Ga, Dec 11-14, 2021. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2021-148379 |
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2021 Conference Publication A Phase- Ib/II Clinical Evaluation of Ponatinib in Combination with Azacitidine in FLT<sub>3</sub>-ITD and CBL-Mutant Acute Myeloid Leukemia (PON-AZA study)Kipp, David, Loo, Sun, Perkins, Andrew Charles, Lane, Steven W., Blyth, Emily, Ejeti, Anoop Kumar, Bajel, Ashish, Reynolds, John and Wei, Andrew H. (2021). A Phase- Ib/II Clinical Evaluation of Ponatinib in Combination with Azacitidine in FLT3-ITD and CBL-Mutant Acute Myeloid Leukemia (PON-AZA study). 63rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta Ga, Dec 11-14, 2021. WASHINGTON: AMER SOC HEMATOLOGY. doi: 10.1182/blood-2021-154247 |
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2021 Journal Article Do women with HIV/AIDS on anti-retroviral therapy have a lower incidence of symptoms associated with menstrual dysfunction?Tempest, Nicola, Edirisinghe, Damitha N., Lane, Steven and Hapangama, Dharani K. (2021). Do women with HIV/AIDS on anti-retroviral therapy have a lower incidence of symptoms associated with menstrual dysfunction?. European Journal of Obstetrics and Gynecology and Reproductive Biology, 265, 137-142. doi: 10.1016/j.ejogrb.2021.08.027 |
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2021 Journal Article Prevalence of depression and anxiety in patients with chronic obstructive pulmonary disease and their association with psychosocial outcomes: a cross-sectional study from PakistanHusain, Muhammad Omair, Chaudhry, Imran B., Blakemore, Amy, Shakoor, Suleman, Husain, Muhammad Ali, Lane, Steven, Kiran, Tayyeba, Jafri, Farhat, Memon, Rakhshi, Panagioti, Maria and Husain, Nusrat (2021). Prevalence of depression and anxiety in patients with chronic obstructive pulmonary disease and their association with psychosocial outcomes: a cross-sectional study from Pakistan. Sage Open Medicine, 9. doi: 10.1177/20503121211032813 |
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2021 Journal Article Optimizing DNA hypomethylating therapy in acute myeloid leukemia and myelodysplastic syndromesStraube, Jasmin, Lane, Steven W. and Vu, Therese (2021). Optimizing DNA hypomethylating therapy in acute myeloid leukemia and myelodysplastic syndromes. BioEssays, 43 (10) 2100125, 1-14. doi: 10.1002/bies.202100125 |
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2021 Journal Article Expression of CD49f defines subsets of human regulatory T cells with divergent transcriptional landscape and function that correlate with ulcerative colitis disease activityWeerakoon, Harshi, Straube, Jasmin, Lineburg, Katie, Cooper, Leanne, Lane, Steven, Smith, Corey, Alabbas, Saleh, Begun, Jakob, Miles, John J., Hill, Michelle M. and Lepletier, Ailin (2021). Expression of CD49f defines subsets of human regulatory T cells with divergent transcriptional landscape and function that correlate with ulcerative colitis disease activity. Clinical and Translational Immunology, 10 (9) e1334, e1334. doi: 10.1002/cti2.1334 |
