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2018

Journal Article

Impact of Non-Adherence and Flare Resolution on the Cost-Effectiveness of Treatments for Gout: Application of a Linked Pharmacometric/Pharmacoeconomic Model

Hill-McManus, Daniel, Marshall, Scott, Soto, Elena, Lane, Steven and Hughes, Dyfrig (2018). Impact of Non-Adherence and Flare Resolution on the Cost-Effectiveness of Treatments for Gout: Application of a Linked Pharmacometric/Pharmacoeconomic Model. Value in Health, 21 (12), 1373-1381. doi: 10.1016/j.jval.2018.06.002

Impact of Non-Adherence and Flare Resolution on the Cost-Effectiveness of Treatments for Gout: Application of a Linked Pharmacometric/Pharmacoeconomic Model

2018

Journal Article

Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation

Jacquelin, Sebastien, Straube, Jasmin, Cooper, Leanne, Vu, Therese, Song, Axia, Bywater, Megan, Baxter, Eva, Heidecker, Matthew, Wackrow, Brad, Porter, Amy, Ling, Victoria, Green, Joanne, Austin, Rebecca, Kazakoff, Stephen, Waddell, Nicola, Hesson, Luke B., Pimanda, John E., Stegelmann, Frank, Bullinger, Lars, Döhner, Konstanze, Rampal, Raajit K., Heckl, Dirk, Hill, Geoffrey R. and Lane, Steven W. (2018). Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation. Blood, 132 (26), blood-2018. doi: 10.1182/blood-2018-04-846220

Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation

2018

Conference Publication

Recipient mucosal-associated invariant T cells control graft-versus-host-disease within the colon

Varelias, Antiopi, Bunting, Mark, Ormerod, Kate, Koyama, Motoko, Olver, Stuart, Straube, Jasmin, Kuns, Rachel, Robb, Renee, Henden, Andrea, Cooper, Leanne, Lachner, Nancy, Gartlan, Kate, Lantz, Olivier J., Kjer-Nielsen, Lars, Mak, Jeffrey, Fairlie, David, Clouston, Andrew, McCluskey, James, Rossjohn, Jamie, Lane, Steven, Hugenholtz, Phil and Hill, Geoff (2018). Recipient mucosal-associated invariant T cells control graft-versus-host-disease within the colon. Immunology 2018™ Meeting, Austin, TX United States, 4-8 May 2018. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.200.supp.55.15

Recipient mucosal-associated invariant T cells control graft-versus-host-disease within the colon

2018

Journal Article

Recipient mucosal-associated invariant T cells control GVHD within the colon

Varelias, Antiopi, Bunting, Mark D., Ormerod, Kate L., Koyama, Motoko, Olver, Stuart D., Straube, Jasmin, Kuns, Rachel D., Robb, Renee J., Henden, Andrea S., Cooper, Leanne, Lachner, Nancy, Gartlan, Kate H., Lantz, Olivier, Kjer-Nielsen, Lars, Mak, Jeffrey Y. W., Fairlie, David P., Clouston, Andrew D., McCluskey, James, Rossjohn, Jamie, Lane, Steven W., Hugenholtz, Philip and Hill, Geoffrey R. (2018). Recipient mucosal-associated invariant T cells control GVHD within the colon. Journal of Clinical Investigation, 128 (5), 1919-1936. doi: 10.1172/JCI91646

Recipient mucosal-associated invariant T cells control GVHD within the colon

2018

Journal Article

Conventional dendritic cells are required for the cross-presentation of leukemia-specific antigen in a model of AML relapse post-BMT

Markey, Kate A., Gartlan, Kate H., Kuns, Rachel D., Lane, Steven W. and Hill, Geoffrey R. (2018). Conventional dendritic cells are required for the cross-presentation of leukemia-specific antigen in a model of AML relapse post-BMT. Bone Marrow Transplantation, 53 (6), 800-803. doi: 10.1038/s41409-018-0148-y

Conventional dendritic cells are required for the cross-presentation of leukemia-specific antigen in a model of AML relapse post-BMT

2018

Journal Article

The impact of age, NPM1, and FLT3 allelic ratio in patients with acute myeloid leukemia

Straube, Jasmin, Ling, Victoria Y, Hill, Geoffrey R and Lane, Steven W (2018). The impact of age, NPM1, and FLT3 allelic ratio in patients with acute myeloid leukemia. Blood, 131 (10), 1148-1153. doi: 10.1182/blood-2017-09-807438

The impact of age, NPM1, and FLT3 allelic ratio in patients with acute myeloid leukemia

2018

Journal Article

Oncogenic JAK2causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms

Prestipino, Alessandro, Emhardt, Alica J., Aumann, Konrad, O'Sullivan, David, Gorantla, Sivahari P., Duquesne, Sandra, Melchinger, Wolfgang, Braun, Lukas, Vuckovic, Slavica, Boerries, Melanie, Busch, Hauke, Halbach, Sebastian, Pennisi, Sandra, Poggio, Teresa, Apostolova, Petya, Veratti, Pia, Hettich, Michael, Niedermann, Gabriele, Bartholomä, Mark, Shoumariyeh, Khalid, Jutzi, Jonas S., Wehrle, Julius, Dierks, Christine, Becker, Heiko, Schmitt-Graeff, Annette, Follo, Marie, Pfeifer, Dietmar, Rohr, Jan, Fuchs, Sebastian ... Zeiser, Robert (2018). Oncogenic JAK2causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms. Science Translational Medicine, 10 (429) eaam7729, eaam7729. doi: 10.1126/scitranslmed.aam7729

Oncogenic JAK2causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms

2018

Journal Article

IFN regulatory factor 3 balances Th1 and T follicular helper immunity during nonlethal blood-stage Plasmodium infection

James, Kylie R., Soon, Megan S. F., Sebina, Ismail, Fernandez-Ruiz, Daniel, Davey, Gayle, Liligeto, Urijah N., Nair, Arya Sheela, Fogg, Lily G., Edwards, Chelsea L., Best, Shannon E., Lansink, Lianne I. M., Schroder, Kate, Wilson, Jane A. C., Austin, Rebecca, Suhrbier, Andreas, Lane, Steven W., Hill, Geoffrey R., Engwerda, Christian R., Heath, William R. and Haque, Ashraful (2018). IFN regulatory factor 3 balances Th1 and T follicular helper immunity during nonlethal blood-stage Plasmodium infection. Journal of Immunology, 200 (4), 1443-1456. doi: 10.4049/jimmunol.1700782

IFN regulatory factor 3 balances Th1 and T follicular helper immunity during nonlethal blood-stage Plasmodium infection

2018

Journal Article

Flt-3L expansion of recipient CD8α+ dendritic cells deletes alloreactive donor T cells and represents an alternative to post-transplant cyclophosphamide for the prevention of GVHD

Markey, Kate A., Kuns, Rachel D., Browne, Daniel J., Gartlan, Kate H., Robb, Renee J., Martins, J. Paulo, Henden, Andrea S., Minnie, Simone A., Cheong, Melody, Koyama, Motoko, Smyth, Mark J., Steptoe, Raymond J., Belz, Gabrielle, Brocker, Thomas, Degli-Esposti, Mariapia A., Lane, Steven W. and Hill, Geoffrey R. (2018). Flt-3L expansion of recipient CD8α+ dendritic cells deletes alloreactive donor T cells and represents an alternative to post-transplant cyclophosphamide for the prevention of GVHD. Clinical Cancer Research, 24 (7), 1604-1616. doi: 10.1158/1078-0432.CCR-17-2148

Flt-3L expansion of recipient CD8α+ dendritic cells deletes alloreactive donor T cells and represents an alternative to post-transplant cyclophosphamide for the prevention of GVHD

2018

Journal Article

Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes

Chong, C. -E., Venugopal, P., Stokes, P. H., Lee, Y. K., Brautigan, P. J., Yeung, D. T. O., Babic, M., Engler, G. A., Lane, S. W., Klingler-Hoffmann, M., Matthews, J. M., D'Andrea, R. J., Brown, A. L., Hahn, C. N. and Scott, H. S. (2018). Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes. Leukemia, 32 (1), 194-202. doi: 10.1038/leu.2017.196

Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes

2017

Journal Article

Clinical and molecular categorization of progressive, adult-onset cutaneous mastocytosis

Tate, Courtney, Tang, Fiona, Lane, Steven W. and Seymour, Louise (2017). Clinical and molecular categorization of progressive, adult-onset cutaneous mastocytosis. JAAD Case Reports, 4 (1), 30-32. doi: 10.1016/j.jdcr.2017.09.038

Clinical and molecular categorization of progressive, adult-onset cutaneous mastocytosis

2017

Journal Article

Acute myeloid leukemia stem cell function is preserved in the absence of autophagy

Porter, Amy H., Leveque-El Mouttie, Lucie, Vu, Therese, Bruedigam, Claudia, Sutton, Joanne, Jacquelin, Sebastien, Hill, Geoffrey R., MacDonald, Kelli P. A. and Lane, Steven W. (2017). Acute myeloid leukemia stem cell function is preserved in the absence of autophagy. Haematologica, 102 (9), E344-E347. doi: 10.3324/haematol.2017.166389

Acute myeloid leukemia stem cell function is preserved in the absence of autophagy

2017

Journal Article

Hacking the stem cell niche

Lane, Steven W. and Heidel, Florian H. (2017). Hacking the stem cell niche. Blood, 129 (22), 2951-2952. doi: 10.1182/blood-2017-04-777789

Hacking the stem cell niche

2017

Journal Article

Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress

Shi, Wei, Vu, Therese, Boucher, Didier, Biernacka, Anna, Nde, Jules, Pandita, Raj K., Straube, Jasmin, Boyle, Glen M., Al-Ejeh, Fares, Nag, Purba, Jeffery, Jessie, Harris, Janelle L., Bain, Amanda L., Grzelak, Marta, Skrzypczak, Magdalena, Mitra, Abhishek, Dojer, Norbert, Crosetto, Nicola, Cloonan, Nicole, Becherel, Olivier J., Finnie, John, Skaar, Jeffrey R., Walkley, Carl R., Pandita, Tej K., Rowicka, Maga, Ginalski, Krzysztof, Lane, Steven W. and Khanna, Kum Kum (2017). Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress. Blood, 129 (18), 2479-2492. doi: 10.1182/blood-2016-06-725093

Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress

2017

Journal Article

Global prevalence of carbapenem resistance in neutropenic patients and association with mortality and carbapenem use: systematic review and meta-analysis

Righi, Elda, Peri, Anna Maria, Harris, Patrick N. A., Wailan, Alexander M., Liborio, Mariana, Lane, Steven W. and Paterson, David L. (2017). Global prevalence of carbapenem resistance in neutropenic patients and association with mortality and carbapenem use: systematic review and meta-analysis. Journal of Antimicrobial Chemotherapy, 72 (3), 668-677. doi: 10.1093/jac/dkw459

Global prevalence of carbapenem resistance in neutropenic patients and association with mortality and carbapenem use: systematic review and meta-analysis

2017

Journal Article

GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity

Bunting, Mark D., Varelias, Antiopi, Souza-Fonseca-Guimaraes, Fernando, Schuster, Iona S., Lineburg, Katie E., Kuns, Rachel D., Fleming, Peter, Locke, Kelly R., Huntington, Nicholas D., Blazar, Bruce R., Lane, Steven W., Tey, Siok-Keen, MacDonald, Kelli P. A., Smyth, Mark J., Degli-Esposti, Mariapia A. and Hill, Geoffrey R. (2017). GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity. Blood, 129 (5), 630-642. doi: 10.1182/blood-2016-08-734020

GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity

2016

Journal Article

An unhealthy diet: making sense of a fatty niche for leukemia stem cells

Jacquelin, Sebastien, Dishington, Emma J. and Lane, Steven W. (2016). An unhealthy diet: making sense of a fatty niche for leukemia stem cells. Translational Cancer Research, 5 (S4), S878-S881. doi: 10.21037/tcr.2016.10.43

An unhealthy diet: making sense of a fatty niche for leukemia stem cells

2016

Conference Publication

IL-28 Is a critical cytoprotectant in transplantation

Henden, A., Robb, R., Clouston, A., Kuns, R., Lane, S., Gartlan, K. and Hill, G. (2016). IL-28 Is a critical cytoprotectant in transplantation. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley-VCH.

IL-28 Is a critical cytoprotectant in transplantation

2016

Journal Article

Harnessing the immune system in acute myeloid leukaemia

Austin, Rebecca, Smyth, Mark J. and Lane, Steven W. (2016). Harnessing the immune system in acute myeloid leukaemia. Critical Reviews in Oncology/Hematology, 103, 62-77. doi: 10.1016/j.critrevonc.2016.04.020

Harnessing the immune system in acute myeloid leukaemia

2016

Journal Article

Telomerase in hematologic malignancies

Bruedigam, Claudia and Lane, Steven W. (2016). Telomerase in hematologic malignancies. Current Opinion in Hematology, 23 (4), 346-353. doi: 10.1097/MOH.0000000000000252

Telomerase in hematologic malignancies