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2022 Journal Article Better the cure you know: why patients with AML ≥60 years of age should be offered early allogeneic stem cell transplantationTey, Siok-Keen and Lane, Steven W (2022). Better the cure you know: why patients with AML ≥60 years of age should be offered early allogeneic stem cell transplantation. Blood Advances, 6 (5), 1619-1622. doi: 10.1182/bloodadvances.2021004829 |
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2022 Journal Article PLCG1 is required for AML1-ETO leukemia stem cell self-renewalSchnoeder, Tina M., Schwarzer, Adrian, Jayavelu, Ashok Kumar, Hsu, Chen-Jen, Kirkpatrick, Joanna, Döhner, Konstanze, Perner, Florian, Eifert, Theresa, Huber, Nicolas, Arreba-Tutusaus, Patricia, Dolnik, Anna, Assi, Salam A, Nafria, Monica, Jiang, Lu, Dai, Yu-Ting, Chen, Zhu, Chen, Sai-Juan, Kellaway, Sophie G., Ptasinska, Anetta, Ng, Elizabeth S., Stanley, Edouard G., Elefanty, Andrew G., Buschbeck, Marcus, Bierhoff, Holger, Brodt, Steffen, Matziolis, Georg, Fischer, Klaus-Dieter, Hochhaus, Andreas, Chen, Chun-Wei ... Heidel, Florian (2022). PLCG1 is required for AML1-ETO leukemia stem cell self-renewal. Blood, 139 (7), 1080-1097. doi: 10.1182/blood.2021012778 |
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2022 Journal Article Reduction of NETosis by targeting CXCR1/2 reduces thrombosis, lung injury, and mortality in experimental human and murine sepsisAlsabani, Mohmad, Abrams, Simon T., Cheng, Zhenxing, Morton, Ben, Lane, Steven, Alosaimi, Samar, Yu, Weiping, Wang, Guozheng and Toh, Cheng-Hock (2022). Reduction of NETosis by targeting CXCR1/2 reduces thrombosis, lung injury, and mortality in experimental human and murine sepsis. British Journal of Anaesthesia, 128 (2), 283-293. doi: 10.1016/j.bja.2021.10.039 |
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2021 Conference Publication Targeting Control of Cell Cycle Enhances the Activity of Conventional Chemotherapy in Chemotherapy-Resistant Acute Myeloid LeukemiaLing, Victoria Y., Jacquelin, Sebastien, Straube, Jasmin, Haldar, Rohit, Janardhanan, Yashaswini, Cooper, Leanne T., Bruedigam, Claudia, Cooper, Emily, Godfrey, William, Tey, Siok-Keen, Bullinger, Lars, Herold, Marco J., Baell, Jonathan, Bywater, Megan and Lane, Steven W. (2021). Targeting Control of Cell Cycle Enhances the Activity of Conventional Chemotherapy in Chemotherapy-Resistant Acute Myeloid Leukemia. 63rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta Ga, Dec 11-14, 2021. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2021-148379 |
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2021 Conference Publication A Phase- Ib/II Clinical Evaluation of Ponatinib in Combination with Azacitidine in FLT<sub>3</sub>-ITD and CBL-Mutant Acute Myeloid Leukemia (PON-AZA study)Kipp, David, Loo, Sun, Perkins, Andrew Charles, Lane, Steven W., Blyth, Emily, Ejeti, Anoop Kumar, Bajel, Ashish, Reynolds, John and Wei, Andrew H. (2021). A Phase- Ib/II Clinical Evaluation of Ponatinib in Combination with Azacitidine in FLT3-ITD and CBL-Mutant Acute Myeloid Leukemia (PON-AZA study). 63rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta Ga, Dec 11-14, 2021. WASHINGTON: AMER SOC HEMATOLOGY. doi: 10.1182/blood-2021-154247 |
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2021 Conference Publication A Phase 2 Study of the LSD1 Inhibitor Img-7289 (bomedemstat) for the Treatment of Essential Thrombocythemia (ET)Palandri, Francesca, Vianelli, Nicola, Ross, David M., Cochrane, Tara, Lane, Steven W., Larsen, Stephen R., Gerds, Aaron T., Halpern, Anna B., Shortt, Jake, Rossetti, James M., Pettit, Kristen M., Jones, Amber, Peppe, Jennifer, Natsoulis, Georges, Navarro, Willis, Hong, Wan-Jen, Stevenson, William S., Harrison, Claire N., Talpaz, Moshe and Rienhoff, Hugh Young (2021). A Phase 2 Study of the LSD1 Inhibitor Img-7289 (bomedemstat) for the Treatment of Essential Thrombocythemia (ET). 63rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta Ga, Dec 11-14, 2021. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2021-148210 |
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2021 Journal Article Do women with HIV/AIDS on anti-retroviral therapy have a lower incidence of symptoms associated with menstrual dysfunction?Tempest, Nicola, Edirisinghe, Damitha N., Lane, Steven and Hapangama, Dharani K. (2021). Do women with HIV/AIDS on anti-retroviral therapy have a lower incidence of symptoms associated with menstrual dysfunction?. European Journal of Obstetrics and Gynecology and Reproductive Biology, 265, 137-142. doi: 10.1016/j.ejogrb.2021.08.027 |
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2021 Journal Article Prevalence of depression and anxiety in patients with chronic obstructive pulmonary disease and their association with psychosocial outcomes: a cross-sectional study from PakistanHusain, Muhammad Omair, Chaudhry, Imran B., Blakemore, Amy, Shakoor, Suleman, Husain, Muhammad Ali, Lane, Steven, Kiran, Tayyeba, Jafri, Farhat, Memon, Rakhshi, Panagioti, Maria and Husain, Nusrat (2021). Prevalence of depression and anxiety in patients with chronic obstructive pulmonary disease and their association with psychosocial outcomes: a cross-sectional study from Pakistan. Sage Open Medicine, 9. doi: 10.1177/20503121211032813 |
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2021 Journal Article Optimizing DNA hypomethylating therapy in acute myeloid leukemia and myelodysplastic syndromesStraube, Jasmin, Lane, Steven W. and Vu, Therese (2021). Optimizing DNA hypomethylating therapy in acute myeloid leukemia and myelodysplastic syndromes. BioEssays, 43 (10) 2100125, 1-14. doi: 10.1002/bies.202100125 |
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2021 Journal Article cardiac pathology and outcomes vary between Kawasaki disease and PIMS-TS (vol 229, 108780, 2021)Felsenstein, S., Duong, P., Lane, S., Jones, C., Paine, C. E. and Hedrich, C. M. (2021). cardiac pathology and outcomes vary between Kawasaki disease and PIMS-TS (vol 229, 108780, 2021). Clinical Immunology, 231 108855, 108855. doi: 10.1016/j.clim.2021.108855 |
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2021 Journal Article Expression of CD49f defines subsets of human regulatory T cells with divergent transcriptional landscape and function that correlate with ulcerative colitis disease activityWeerakoon, Harshi, Straube, Jasmin, Lineburg, Katie, Cooper, Leanne, Lane, Steven, Smith, Corey, Alabbas, Saleh, Begun, Jakob, Miles, John J., Hill, Michelle M. and Lepletier, Ailin (2021). Expression of CD49f defines subsets of human regulatory T cells with divergent transcriptional landscape and function that correlate with ulcerative colitis disease activity. Clinical and Translational Immunology, 10 (9) e1334, e1334. doi: 10.1002/cti2.1334 |
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2021 Journal Article Circulating histones play a central role in COVID-19-associated coagulopathy and mortalityShaw, Rebecca J., Abrams, Simon T., Austin, James, Taylor, Joseph M., Lane, Steven, Dutt, Tina, Downey, Colin, Du, Min, Turtle, Lance, Baillie, J. Kenneth, Openshaw, Peter J. M., Wang, Guozheng, Semple, Malcolm G. and Toh, Cheng-Hock (2021). Circulating histones play a central role in COVID-19-associated coagulopathy and mortality. Haematologica, 106 (9), 2493-2498. doi: 10.3324/haematol.2021.278492 |
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2021 Journal Article Are public health measures and individualised care compatible in the face of a pandemic? A national observational study of bereaved relatives' experiences during the COVID-19 pandemicMayland, Catriona R., Hughes, Rosemary, Lane, Steven, McGlinchey, Tamsin, Donnellan, Warren, Bennett, Kate, Hanna, Jeffrey, Rapa, Elizabeth, Dalton, Louise and Mason, Stephen R. (2021). Are public health measures and individualised care compatible in the face of a pandemic? A national observational study of bereaved relatives' experiences during the COVID-19 pandemic. Palliative Medicine, 35 (8), 1480-1491. doi: 10.1177/02692163211019885 |
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2021 Journal Article Cardiac pathology and outcomes vary between Kawasaki disease and PIMS-TSFelsenstein, Susanna, Duong, Phuoc, Lane, Steven, Jones, Caroline, Pain, Clare E. and Hedrich, Christian M. (2021). Cardiac pathology and outcomes vary between Kawasaki disease and PIMS-TS. Clinical Immunology, 229 108780, 1-7. doi: 10.1016/j.clim.2021.108780 |
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2021 Journal Article Ataxia and mobility in children following surgical resection of posterior fossa tumour: a longitudinal cohort studyHartley, H., Lane, S., Pizer, B., Bunn, L., Carter, B., Cassidy, E., Mallucci, C. and Kumar, R. (2021). Ataxia and mobility in children following surgical resection of posterior fossa tumour: a longitudinal cohort study. Childs Nervous System, 37 (9), 2831-2838. doi: 10.1007/s00381-021-05246-0 |
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2021 Journal Article Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemiasThijssen, Rachel, Diepstraten, Sarah T., Moujalled, Donia, Chew, Edward, Flensburg, Christoffer, Shi, Melissa X., Dengler, Michael A., Litalien, Veronique, MacRaild, Sarah, Chen, Maoshan, Anstee, Natasha S., Reljić, Boris, Gabriel, Sarah S., Djajawi, Tirta M., Riffkin, Chris D., Aubrey, Brandon J., Chang, Catherine, Tai, Lin, Xu, Zhen, Morley, Thomas, Pomilio, Giovanna, Bruedigam, Claudia, Kallies, Axel, Stroud, David A., Bajel, Ashish, Kluck, Ruth M., Lane, Steven W., Schoumacher, Marie, Banquet, Sébastien ... Wei, Andrew H. (2021). Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias. Blood, 137 (20), 2721-2735. doi: 10.1182/blood.2020010167 |
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2021 Journal Article IFN-λ therapy prevents severe gastrointestinal graft-versus-host diseaseHenden, Andrea S., Koyama, Motoko, Robb, Renee J., Forero, Adriana, Kuns, Rachel D., Chang, Karshing, Ensbey, Kathleen S., Varelias, Antiopi, Kazakoff, Stephen H., Waddell, Nicole, Clouston, Andrew D., Giri, Rabina, Begun, Jakob, Blazar, Bruce R., Degli-Esposti, Mariapia A., Kotenko, Sergei V., Lane, Steven W., Bowerman, Kate L., Savan, Ram, Hugenholtz, Philip, Gartlan, Kate H. and Hill, Geoffrey R. (2021). IFN-λ therapy prevents severe gastrointestinal graft-versus-host disease. Blood, 138 (8), 722-737. doi: 10.1182/blood.2020006375 |
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2021 Journal Article Pilot of the Patient Concerns Inventory - Ward Discharge in patients following major reconstructive surgery for head and neck cancerIndoe, J., Lane, S., Davies, K. and Rogers, S. N. (2021). Pilot of the Patient Concerns Inventory - Ward Discharge in patients following major reconstructive surgery for head and neck cancer. British Journal of Oral and Maxillofacial Surgery, 59 (4), 425-432. doi: 10.1016/j.bjoms.2020.08.080 |
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2021 Journal Article Myeloid somatic mutation panel testing in myeloproliferative neoplasmsRoss, David M., Thomson, Candice, Hamad, Nada, Lane, Steven W., Manos, Kate, Grigg, Andrew P., Guo, Belinda, Erber, Wendy N., Scott, Ashleigh, Viiala, Nick, Chee, Lynette, Latimer, Maya, Tate, Courtney, Grove, Carolyn, Perkins, Andrew C. and Blombery, Piers (2021). Myeloid somatic mutation panel testing in myeloproliferative neoplasms. Pathology, 53 (3), 339-348. doi: 10.1016/j.pathol.2021.01.003 |
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2021 Journal Article Real-world experience with caplacizumab in the management of acute TTPDutt, Tina, Shaw, Rebecca J., Stubbs, Matthew, Yong, Jun, Bailiff, Benjamin, Cranfield, Tanya, Crowley, Maeve P., Desborough, Michael, Eyre, Toby A., Gooding, Richard, Grainger, John, Hanley, John, Haughton, Joanna, Hermans, Joannes, Hill, Quentin, Humphrey, Louise, Lowe, Gillian, Lyall, Hamish, Mohsin, Muhammad, Nicolson, Phillip L. R., Priddee, Nicole, Rampotas, Alexandros, Rayment, Rachel, Rhodes, Susan, Taylor, Alice, Thomas, William, Tomkins, Oliver, Van Veen, Joost J., Lane, Steven ... Scully, Marie (2021). Real-world experience with caplacizumab in the management of acute TTP. Blood, 137 (13), 1731-1740. doi: 10.1182/blood.2020007599 |
