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2018

Journal Article

The impact of age, NPM1, and FLT3 allelic ratio in patients with acute myeloid leukemia

Straube, Jasmin, Ling, Victoria Y, Hill, Geoffrey R and Lane, Steven W (2018). The impact of age, NPM1, and FLT3 allelic ratio in patients with acute myeloid leukemia. Blood, 131 (10), 1148-1153. doi: 10.1182/blood-2017-09-807438

The impact of age, NPM1, and FLT3 allelic ratio in patients with acute myeloid leukemia

2018

Journal Article

Oncogenic JAK2causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms

Prestipino, Alessandro, Emhardt, Alica J., Aumann, Konrad, O'Sullivan, David, Gorantla, Sivahari P., Duquesne, Sandra, Melchinger, Wolfgang, Braun, Lukas, Vuckovic, Slavica, Boerries, Melanie, Busch, Hauke, Halbach, Sebastian, Pennisi, Sandra, Poggio, Teresa, Apostolova, Petya, Veratti, Pia, Hettich, Michael, Niedermann, Gabriele, Bartholomä, Mark, Shoumariyeh, Khalid, Jutzi, Jonas S., Wehrle, Julius, Dierks, Christine, Becker, Heiko, Schmitt-Graeff, Annette, Follo, Marie, Pfeifer, Dietmar, Rohr, Jan, Fuchs, Sebastian ... Zeiser, Robert (2018). Oncogenic JAK2causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms. Science Translational Medicine, 10 (429) eaam7729, eaam7729. doi: 10.1126/scitranslmed.aam7729

Oncogenic JAK2causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms

2018

Journal Article

IFN regulatory factor 3 balances Th1 and T follicular helper immunity during nonlethal blood-stage Plasmodium infection

James, Kylie R., Soon, Megan S. F., Sebina, Ismail, Fernandez-Ruiz, Daniel, Davey, Gayle, Liligeto, Urijah N., Nair, Arya Sheela, Fogg, Lily G., Edwards, Chelsea L., Best, Shannon E., Lansink, Lianne I. M., Schroder, Kate, Wilson, Jane A. C., Austin, Rebecca, Suhrbier, Andreas, Lane, Steven W., Hill, Geoffrey R., Engwerda, Christian R., Heath, William R. and Haque, Ashraful (2018). IFN regulatory factor 3 balances Th1 and T follicular helper immunity during nonlethal blood-stage Plasmodium infection. Journal of Immunology, 200 (4), 1443-1456. doi: 10.4049/jimmunol.1700782

IFN regulatory factor 3 balances Th1 and T follicular helper immunity during nonlethal blood-stage Plasmodium infection

2018

Journal Article

Flt-3L expansion of recipient CD8α+ dendritic cells deletes alloreactive donor T cells and represents an alternative to post-transplant cyclophosphamide for the prevention of GVHD

Markey, Kate A., Kuns, Rachel D., Browne, Daniel J., Gartlan, Kate H., Robb, Renee J., Martins, J. Paulo, Henden, Andrea S., Minnie, Simone A., Cheong, Melody, Koyama, Motoko, Smyth, Mark J., Steptoe, Raymond J., Belz, Gabrielle, Brocker, Thomas, Degli-Esposti, Mariapia A., Lane, Steven W. and Hill, Geoffrey R. (2018). Flt-3L expansion of recipient CD8α+ dendritic cells deletes alloreactive donor T cells and represents an alternative to post-transplant cyclophosphamide for the prevention of GVHD. Clinical Cancer Research, 24 (7), 1604-1616. doi: 10.1158/1078-0432.CCR-17-2148

Flt-3L expansion of recipient CD8α+ dendritic cells deletes alloreactive donor T cells and represents an alternative to post-transplant cyclophosphamide for the prevention of GVHD

2018

Journal Article

Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes

Chong, C. -E., Venugopal, P., Stokes, P. H., Lee, Y. K., Brautigan, P. J., Yeung, D. T. O., Babic, M., Engler, G. A., Lane, S. W., Klingler-Hoffmann, M., Matthews, J. M., D'Andrea, R. J., Brown, A. L., Hahn, C. N. and Scott, H. S. (2018). Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes. Leukemia, 32 (1), 194-202. doi: 10.1038/leu.2017.196

Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes

2017

Journal Article

Clinical and molecular categorization of progressive, adult-onset cutaneous mastocytosis

Tate, Courtney, Tang, Fiona, Lane, Steven W. and Seymour, Louise (2017). Clinical and molecular categorization of progressive, adult-onset cutaneous mastocytosis. JAAD Case Reports, 4 (1), 30-32. doi: 10.1016/j.jdcr.2017.09.038

Clinical and molecular categorization of progressive, adult-onset cutaneous mastocytosis

2017

Journal Article

Clinical relevance of findings in trials of CBT for depression

Lepping, P., Whittington, R., Sambhi, R. S., Lane, S., Poole, R., Leucht, S., Cuijpers, P., McCabe, R. and Waheed, W. (2017). Clinical relevance of findings in trials of CBT for depression. European Psychiatry, 45, 207-211. doi: 10.1016/j.eurpsy.2017.07.003

Clinical relevance of findings in trials of CBT for depression

2017

Journal Article

Acute myeloid leukemia stem cell function is preserved in the absence of autophagy

Porter, Amy H., Leveque-El Mouttie, Lucie, Vu, Therese, Bruedigam, Claudia, Sutton, Joanne, Jacquelin, Sebastien, Hill, Geoffrey R., MacDonald, Kelli P. A. and Lane, Steven W. (2017). Acute myeloid leukemia stem cell function is preserved in the absence of autophagy. Haematologica, 102 (9), E344-E347. doi: 10.3324/haematol.2017.166389

Acute myeloid leukemia stem cell function is preserved in the absence of autophagy

2017

Journal Article

Hacking the stem cell niche

Lane, Steven W. and Heidel, Florian H. (2017). Hacking the stem cell niche. Blood, 129 (22), 2951-2952. doi: 10.1182/blood-2017-04-777789

Hacking the stem cell niche

2017

Journal Article

Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress

Shi, Wei, Vu, Therese, Boucher, Didier, Biernacka, Anna, Nde, Jules, Pandita, Raj K., Straube, Jasmin, Boyle, Glen M., Al-Ejeh, Fares, Nag, Purba, Jeffery, Jessie, Harris, Janelle L., Bain, Amanda L., Grzelak, Marta, Skrzypczak, Magdalena, Mitra, Abhishek, Dojer, Norbert, Crosetto, Nicola, Cloonan, Nicole, Becherel, Olivier J., Finnie, John, Skaar, Jeffrey R., Walkley, Carl R., Pandita, Tej K., Rowicka, Maga, Ginalski, Krzysztof, Lane, Steven W. and Khanna, Kum Kum (2017). Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress. Blood, 129 (18), 2479-2492. doi: 10.1182/blood-2016-06-725093

Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress

2017

Journal Article

Global prevalence of carbapenem resistance in neutropenic patients and association with mortality and carbapenem use: systematic review and meta-analysis

Righi, Elda, Peri, Anna Maria, Harris, Patrick N. A., Wailan, Alexander M., Liborio, Mariana, Lane, Steven W. and Paterson, David L. (2017). Global prevalence of carbapenem resistance in neutropenic patients and association with mortality and carbapenem use: systematic review and meta-analysis. Journal of Antimicrobial Chemotherapy, 72 (3), 668-677. doi: 10.1093/jac/dkw459

Global prevalence of carbapenem resistance in neutropenic patients and association with mortality and carbapenem use: systematic review and meta-analysis

2017

Journal Article

GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity

Bunting, Mark D., Varelias, Antiopi, Souza-Fonseca-Guimaraes, Fernando, Schuster, Iona S., Lineburg, Katie E., Kuns, Rachel D., Fleming, Peter, Locke, Kelly R., Huntington, Nicholas D., Blazar, Bruce R., Lane, Steven W., Tey, Siok-Keen, MacDonald, Kelli P. A., Smyth, Mark J., Degli-Esposti, Mariapia A. and Hill, Geoffrey R. (2017). GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity. Blood, 129 (5), 630-642. doi: 10.1182/blood-2016-08-734020

GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity

2016

Journal Article

An unhealthy diet: making sense of a fatty niche for leukemia stem cells

Jacquelin, Sebastien, Dishington, Emma J. and Lane, Steven W. (2016). An unhealthy diet: making sense of a fatty niche for leukemia stem cells. Translational Cancer Research, 5 (S4), S878-S881. doi: 10.21037/tcr.2016.10.43

An unhealthy diet: making sense of a fatty niche for leukemia stem cells

2016

Conference Publication

IL-28 Is a critical cytoprotectant in transplantation

Henden, A., Robb, R., Clouston, A., Kuns, R., Lane, S., Gartlan, K. and Hill, G. (2016). IL-28 Is a critical cytoprotectant in transplantation. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley-VCH.

IL-28 Is a critical cytoprotectant in transplantation

2016

Journal Article

Harnessing the immune system in acute myeloid leukaemia

Austin, Rebecca, Smyth, Mark J. and Lane, Steven W. (2016). Harnessing the immune system in acute myeloid leukaemia. Critical Reviews in Oncology/Hematology, 103, 62-77. doi: 10.1016/j.critrevonc.2016.04.020

Harnessing the immune system in acute myeloid leukaemia

2016

Journal Article

Telomerase in hematologic malignancies

Bruedigam, Claudia and Lane, Steven W. (2016). Telomerase in hematologic malignancies. Current Opinion in Hematology, 23 (4), 346-353. doi: 10.1097/MOH.0000000000000252

Telomerase in hematologic malignancies

2016

Journal Article

Jak2V617F driven myeloproliferative neoplasm occurs independently of interleukin-3 receptor beta common signalling

Vu, Therese, Austin, Rebecca, Kuhn, Catherine Paine, Bruedigam, Claudia, Song, Axia, Guignes, Solene, Jacquelin, Sebastien, Ramshaw, Hayley S., Hill, Geoffrey R., Lopez, Angel F. and Lane, Steven W. (2016). Jak2V617F driven myeloproliferative neoplasm occurs independently of interleukin-3 receptor beta common signalling. Haematologica, 101 (3), E77-E80. doi: 10.3324/haematol.2015.136705

Jak2V617F driven myeloproliferative neoplasm occurs independently of interleukin-3 receptor beta common signalling

2016

Journal Article

Analysis of telomerase target gene expression effects from murine models in patient cohorts by homology translation and random survival forest modeling

Bagger, Frederik Otzen, Bruedigam, Claudia and Lane, Steven W. (2016). Analysis of telomerase target gene expression effects from murine models in patient cohorts by homology translation and random survival forest modeling. Genomics Data, 7, 275-280. doi: 10.1016/j.gdata.2016.01.014

Analysis of telomerase target gene expression effects from murine models in patient cohorts by homology translation and random survival forest modeling

2015

Journal Article

Increased risk of melanoma in patients with chronic lymphocytic leukaemia: systematic review and meta-analysis of cohort studies

Olsen, Catherine M., Lane, Steven W. and Green, Adèle C. (2015). Increased risk of melanoma in patients with chronic lymphocytic leukaemia: systematic review and meta-analysis of cohort studies. Melanoma Research, 26 (2), 188-194. doi: 10.1097/CMR.0000000000000219

Increased risk of melanoma in patients with chronic lymphocytic leukaemia: systematic review and meta-analysis of cohort studies

2015

Journal Article

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8<sup>+</sup> T cells that induce GVHD without antileukemic effects

Gartlan, Kate H., Markey, Kate A., Varelias, Antiopi, Bunting, Mark D., Koyama, Motoko, Kuns, Rachel D., Raffelt, Neil C., Olver, Stuart D., Lineburg, Katie E., Cheong, Melody, Teal, Bianca E., Lor, Mary, Comerford, Iain, Teng, Michele W. L., Smyth, Mark J., McCluskey, James, Rossjohn, Jamie, Stockinger, Brigitta, Boyle, Glen M., Lane, Steven W., Clouston, Andrew D., McColl, Shaun R., MacDonald, Kelli P. A. and Hill, Geoffrey R. (2015). Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects. Blood, 126 (13), 1609-1620. doi: 10.1182/blood-2015-01-622662

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8<sup>+</sup> T cells that induce GVHD without antileukemic effects