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2026

Journal Article

Homozygous kinase-dead <i>Csf1r</i> mutation in outbred mice reveals essential and redundant functions of tissue resident macrophages

Jacquelin, Sebastien, Maxwell, Emma, Taylor, Isis, Green, Emma, O’Brien, Conan J O, Jessen, Eline E, Ranpura, Ginell, Guo, Jintao, Nooru-Mohamed, Fathima, Liu, Yajun, Keshvari, Sahar, Huang, Stephen, Cooper, Emily, Lane, Steven W, Flegg, Cameron, Kasherman, Maria A, Sokolowski, Kamil, Pettit, Allison R, Hume, David A and Irvine, Katharine M (2026). Homozygous kinase-dead Csf1r mutation in outbred mice reveals essential and redundant functions of tissue resident macrophages. Journal of Leukocyte Biology qiag074. doi: 10.1093/jleuko/qiag074

Homozygous kinase-dead <i>Csf1r</i> mutation in outbred mice reveals essential and redundant functions of tissue resident macrophages

2026

Journal Article

Single cell long read genotyping of transcripts reveals discrete mechanisms of clonal evolution in post-MPN AML

Grabek, Julian, Straube, Jasmin M, Cooper, Leanne, Halder, Rohit, Zhang, Ranran, Dulige, Inken, Barker, Matthew A, Gatehouse, Will, Christensen, Helen, Amor, Gerlinda, Ling, Victoria Y, McNamara, Caroline, Ross, David M., Perkins, Andrew C, Bywater, Megan J. and Lane, Steven W (2026). Single cell long read genotyping of transcripts reveals discrete mechanisms of clonal evolution in post-MPN AML. Blood Advances bloodadvances.2025018902. doi: 10.1182/bloodadvances.2025018902

Single cell long read genotyping of transcripts reveals discrete mechanisms of clonal evolution in post-MPN AML

2026

Journal Article

Dose-dependent impairment of brain functional and microstructural connectivity during leukaemia chemotherapy

Scott, Ashleigh P., Lo, Ada, Xia, Ying, Thompson, Kate, Bodimeade, Harriet, Fazlollahi, Amir, Weber, Nicholas, Curley, Cameron, Hunt, Stewart, Morris, Kirk, McNamara, Caroline, Perera, Nilu, Subramoniapillai, Elango, Lane, Steven W., Kennedy, Glen A., Salvado, Olivier, Urriola, Javier and McMahon, Katie L. (2026). Dose-dependent impairment of brain functional and microstructural connectivity during leukaemia chemotherapy. British Journal of Haematolog, 208 (5) bjh.70386, 1692-1703. doi: 10.1111/bjh.70386

Dose-dependent impairment of brain functional and microstructural connectivity during leukaemia chemotherapy

2026

Journal Article

CD38+ monocytes fuel fibrosis in myeloproliferative neoplasm

Johansson, Alban and Lane, Steven W. (2026). CD38+ monocytes fuel fibrosis in myeloproliferative neoplasm. Blood, 147 (9), 907-909. doi: 10.1182/blood.2025032444

CD38+ monocytes fuel fibrosis in myeloproliferative neoplasm

2025

Journal Article

How accurate are witnesses of first suspected seizures in recalling semiology at clinically relevant timepoints? A UK experimental study with a pilot intervention

Noble, Adam J., Lane, Steven, New, Paul, Cope, Harriet, Foley, Chloe, Williams, Holly Lynn, Sztriha, Laszlo, Powell, Graham, Reuber, Markus and Marson, Anthony G. (2025). How accurate are witnesses of first suspected seizures in recalling semiology at clinically relevant timepoints? A UK experimental study with a pilot intervention. Epilepsia, 66 (12) epi.18624, 4795-4808. doi: 10.1111/epi.18624

How accurate are witnesses of first suspected seizures in recalling semiology at clinically relevant timepoints? A UK experimental study with a pilot intervention

2025

Journal Article

Australasian Leukaemia and Lymphoma Group. Asciminib monotherapy as frontline treatment of chronic-phase chronic myeloid leukemia: results from the ASCEND study (vol 144, pg 1993, 2024)

Yeung, David T., Shanmuganathan, Naranie, Reynolds, John, Branford, Susan, Walia, Mannu, Yong, Agnes S. M., Shortt, Jake, Chee, Lynette, Viiala, Nicholas, Cunningham, Ilona, Ross, David M., D'Souza, Alwyn, Wright, Matthew, Harrup, Rosemary, Forsyth, Cecily, Filshie, Robin, Lane, Steven, Browett, Peter, Grove, Carolyn, Grigg, Andrew P. and Hughes, Timothy P. (2025). Australasian Leukaemia and Lymphoma Group. Asciminib monotherapy as frontline treatment of chronic-phase chronic myeloid leukemia: results from the ASCEND study (vol 144, pg 1993, 2024). Blood, 146 (22), 2729-2729. doi: 10.1182/blood.2025031951

Australasian Leukaemia and Lymphoma Group. Asciminib monotherapy as frontline treatment of chronic-phase chronic myeloid leukemia: results from the ASCEND study (vol 144, pg 1993, 2024)

2025

Journal Article

Decoding RNA modifications to unlock new treatments for AML

Lane, Steven W. and Bywater, Megan (2025). Decoding RNA modifications to unlock new treatments for AML. Blood, 146 (20), 2378-2379. doi: 10.1182/blood.2025030290

Decoding RNA modifications to unlock new treatments for AML

2025

Journal Article

Bcl-xL inhibition potentiates interferon-induced apoptosis in MPN stem cells

Bywater, Megan J., Haldar, Rohit, Janardhanan, Yashaswini, Cooper, Emily, Cooper, Leanne, Chan, Siu Hang Natalie, Hayes, Noah Jack, Ling, Victoria, Straube, Jasmin M. and Lane, Steven W. (2025). Bcl-xL inhibition potentiates interferon-induced apoptosis in MPN stem cells. Blood Advances, 9 (22), 5915-5919. doi: 10.1182/bloodadvances.2025017242

Bcl-xL inhibition potentiates interferon-induced apoptosis in MPN stem cells

2025

Journal Article

Durable responses to lenzilumab: azacitidine combination therapy in high risk proliferative chronic myelomonocytic leukaemia with suppression of CBL and RAS mutant subclones

Thomas, Daniel, Ross, David, Hughes, Timothy, Yeung, David, Kutyna, Monika, Lim, Kelly, Lane, Steven, Yong, Agnes, Reynolds, John and Hiwase, Devendra (2025). Durable responses to lenzilumab: azacitidine combination therapy in high risk proliferative chronic myelomonocytic leukaemia with suppression of CBL and RAS mutant subclones. EMJ Hematology, 13 (1), 66-67. doi: 10.33590/emjhematol/wvmu7856

Durable responses to lenzilumab: azacitidine combination therapy in high risk proliferative chronic myelomonocytic leukaemia with suppression of CBL and RAS mutant subclones

2025

Journal Article

Assessing the performance of paediatric early warning scores to predict critical deterioration events in hospitalised children (the DETECT study): a retrospective matched case-control study

Bracken, Abbey, Lane, Steven, Siner, Sarah, Jones, Dawn, Lambert, Caroline, Mehta, Fulya, Eyton-Chong, Chin-Kien, Davis, Peter, Fitzsimons, John, Lim, Emma, Clerihew, Linda, Carter, Bernie, Sefton, Gerri and Carrol, Enitan D. (2025). Assessing the performance of paediatric early warning scores to predict critical deterioration events in hospitalised children (the DETECT study): a retrospective matched case-control study. BMC Pediatrics, 25 (1) 520, 1-10. doi: 10.1186/s12887-025-05754-x

Assessing the performance of paediatric early warning scores to predict critical deterioration events in hospitalised children (the DETECT study): a retrospective matched case-control study

2025

Journal Article

Clinical prediction models for febrile neutropenia and its outcomes: a systematic review

Sheehy, Joshua, Gallanagh, Marianne, Sullivan, Clair and Lane, Steven (2025). Clinical prediction models for febrile neutropenia and its outcomes: a systematic review. Supportive Care in Cancer, 33 (7) 537, 537. doi: 10.1007/s00520-025-09562-y

Clinical prediction models for febrile neutropenia and its outcomes: a systematic review

2025

Journal Article

Prevention, diagnosis and management of myeloproliferative neoplasms: an introduction to a review series

Yuan, Yin and Lane, Steven W. (2025). Prevention, diagnosis and management of myeloproliferative neoplasms: an introduction to a review series. Haematologica, 110 (4), 825-827. doi: 10.3324/haematol.2024.285414

Prevention, diagnosis and management of myeloproliferative neoplasms: an introduction to a review series

2025

Journal Article

ALLG APML5: Bioavailability and safety of oral arsenic trioxide assessed during consolidation therapy for APL

Iland, Harry J., Reynolds, John, Boddy, Alan, Schultz, Hayley B., Khoo, Liane, Fleming, Shaun A., Lane, Steven W., Weber, Nicholas, Gasiorowski, Robin, Armytage, Tasman, Harrup, Rosemary Anne, Watson, Anne-Marie, Tan, Peter, Filshie, Robin, Kwok, Fiona, Stevenson, William S., Yuen, Sam L.S., Ng, Ashley Peng Chee, Rowley, Leesa, Marlton, Paula and Wei, Andrew H. (2025). ALLG APML5: Bioavailability and safety of oral arsenic trioxide assessed during consolidation therapy for APL. Blood Advances, 9 (6), 1476-1484. doi: 10.1182/bloodadvances.2024015397

ALLG APML5: Bioavailability and safety of oral arsenic trioxide assessed during consolidation therapy for APL

2025

Journal Article

The PRECISION study protocol: Can cervical stiffness in the second trimester predict preterm birth in high-risk singleton pregnancies? A feasibility, cohort study

Medford, Elizabeth, Lane, Steven, Sharp, Andrew and Care, Angharad (2025). The PRECISION study protocol: Can cervical stiffness in the second trimester predict preterm birth in high-risk singleton pregnancies? A feasibility, cohort study. PLoS One, 20 (2) e0316297, 1-13. doi: 10.1371/journal.pone.0316297

The PRECISION study protocol: Can cervical stiffness in the second trimester predict preterm birth in high-risk singleton pregnancies? A feasibility, cohort study

2024

Journal Article

CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targeting

Lim, Kelly, Kan, Winnie L., Nair, Pramod C., Kutyna, Monika, Lopez, Angel F., Hercus, Timothy, Ross, David M., Lane, Steven, Fong, Chun Yew, Brown, Anna, Yong, Agnes, Yeung, David, Hughes, Timothy, Hiwase, Devendra and Thomas, Daniel (2024). CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targeting. PLoS One, 19 (9 September) e0310641, 1-19. doi: 10.1371/journal.pone.0310641

CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targeting

2024

Journal Article

Identifying disease-modifying potential in myelofibrosis clinical trials

Ross, David M, Lane, Steven W and Harrison, Claire N. (2024). Identifying disease-modifying potential in myelofibrosis clinical trials. Blood Journal, 144 (16), 1679-1688. doi: 10.1182/blood.2024024220

Identifying disease-modifying potential in myelofibrosis clinical trials

2024

Journal Article

Asciminib monotherapy as frontline treatment of chronic-phase chronic myeloid leukemia: results from the ASCEND Study

Yeung, David T., Shanmuganathan, Naranie, Reynolds, John, Branford, Susan, Walia, Mannu, Yong, Agnes S.M., Shortt, Jake, Chee, Lynette, Viiala, Nicholas, Cunningham, Ilona, Ross, David M., D'Souza, Alwyn Bernard, Wright, Matthew, Harrup, Rosemary Anne, Forsyth, Cecily Jane, Filshie, Robin, Lane, Steven W., Browett, Peter J., Grove, Carolyn S., Grigg, Andrew A. and Hughes, Timothy P. (2024). Asciminib monotherapy as frontline treatment of chronic-phase chronic myeloid leukemia: results from the ASCEND Study. Blood Journal, 144 (19), 1993-2001. doi: 10.1182/blood.2024024657

Asciminib monotherapy as frontline treatment of chronic-phase chronic myeloid leukemia: results from the ASCEND Study

2024

Journal Article

Fibrinogen binding to histones in circulation protects against adverse cellular and clinical outcomes

Toh, Julien M., Yong, Jun, Abrams, Simon T., Wang, Lijun, Schofield, Jeremy, Lane, Steven, La Corte, Amy Cilia, Wang, Susan S., Ariëns, Robert A.S., Philippou, Helen, Xie, Jianfeng, Yu, Weiping, Wang, Guozheng and Toh, Cheng-Hock (2024). Fibrinogen binding to histones in circulation protects against adverse cellular and clinical outcomes. Journal of Thrombosis and Haemostasis, 22 (8), 2247-2260. doi: 10.1016/j.jtha.2024.05.009

Fibrinogen binding to histones in circulation protects against adverse cellular and clinical outcomes

2024

Journal Article

Microclots, as defined by amyloid-fibrinogen aggregates, predict risks of disseminated intravascular coagulation and mortality

Scho, Jeremy, Abrams, Simon T., Jenkins, Rosalind, Lane, Steven, Wang, Guozheng and Toh, Cheng-Hock (2024). Microclots, as defined by amyloid-fibrinogen aggregates, predict risks of disseminated intravascular coagulation and mortality. Blood Advances, 8 (10), 2499-2508. doi: 10.1182/bloodadvances.2023012473

Microclots, as defined by amyloid-fibrinogen aggregates, predict risks of disseminated intravascular coagulation and mortality

2024

Journal Article

Autophagy prevents graft failure during murine Graft versus Host Disease

Lineburg, Katie E., Leveque-El Mouttie, Lucie, Hunter, Christopher R., Le Texier, Laeitia, McGirr, Crystal, Teal, Bianca, Blazar, Bruce R., Lane, Steven W., Hill, Geoffrey R., Levesque, Jean-Pierre and MacDonald, Kelli P.A. (2024). Autophagy prevents graft failure during murine Graft versus Host Disease. Blood Advances, 8 (8), 2032-2043. doi: 10.1182/bloodadvances.2023010972

Autophagy prevents graft failure during murine Graft versus Host Disease