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2023

Conference Publication

Suppression of KRAS and CBL Mutations and Hematological Improvement By Lenzilumab and Azacitidine Treatment in Proliferative Chronic Myelomonocytic Leukemia

Kamel, Maha M., Kutyna, Monika, Ross, David M., Lane, Steven W., Thompson-Peach, Chloe, Fong, Chun Yew, Yong, Agnes S. M., Yeung, David T., Hughes, Timothy P., Hiwase, Devendra and Thomas, Daniel (2023). Suppression of KRAS and CBL Mutations and Hematological Improvement By Lenzilumab and Azacitidine Treatment in Proliferative Chronic Myelomonocytic Leukemia. 65th ASH Annual Meeting, San Diego, CA United States, 9-12 December 2023. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2023-188340

Suppression of KRAS and CBL Mutations and Hematological Improvement By Lenzilumab and Azacitidine Treatment in Proliferative Chronic Myelomonocytic Leukemia

2023

Conference Publication

Lenzilumab in Addition to Azacitidine Improves Complete Response Rates in Chronic Myelomonocytic Leukemia

Hiwase, Devendra, Ross, David M., Lane, Steven W., Thompson-Peach, Chloe, Fong, Chun Yew, Yong, Agnes S. M., Yeung, David T., Hughes, Timothy P. and Thomas, Daniel (2023). Lenzilumab in Addition to Azacitidine Improves Complete Response Rates in Chronic Myelomonocytic Leukemia. 65th ASH Annual Meeting, San Diego, CA United States, 9-12 December 2023. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2023-179688

Lenzilumab in Addition to Azacitidine Improves Complete Response Rates in Chronic Myelomonocytic Leukemia

2023

Conference Publication

Trp53-Loss in Hematopoietic Stem Cells Drives the Evolutionary Process of Leukemic Transformation in a Jak2 V617F-Driven Myeloproliferative Neoplasms Mouse Model

Zhang, Ranran, Janardhanan, Yashaswini, Haldar, Rohit, Cooper, Leanne, Jaquelin, Sebastien, Straube, Jasmin, Bywater, Megan and Lane, Steven W. (2023). Trp53-Loss in Hematopoietic Stem Cells Drives the Evolutionary Process of Leukemic Transformation in a Jak2 V617F-Driven Myeloproliferative Neoplasms Mouse Model. 65th ASH Annual Meeting, San Diego, CA United States, 9-12 December 2023. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2023-188150

Trp53-Loss in Hematopoietic Stem Cells Drives the Evolutionary Process of Leukemic Transformation in a Jak2 V617F-Driven Myeloproliferative Neoplasms Mouse Model

2023

Conference Publication

Prospective MRI and neurocognitive assessment of “Chemobrain” in acute myeloid leukaemia: the mineral study

Scott, Ashleigh, Lo, Ada, Thompson, Kate, Xia, Ying, Bodimeade, Harriet, Fazlollahi, Amir, Curley, Cameron, Lane, Steven W., Morris, Kirk Lachlan, McNamara, Caroline Jane, Pillai, Elango S., Weber, Nicholas, Salvado, Olivier, McMahon, Katie L. and Kennedy, Glen A. (2023). Prospective MRI and neurocognitive assessment of “Chemobrain” in acute myeloid leukaemia: the mineral study. 65th American Society of Hematology (ASH) Annual Meeting and Exposition, San Diego, CA, United States, 9-12 December 2023. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2023-190301

Prospective MRI and neurocognitive assessment of “Chemobrain” in acute myeloid leukaemia: the mineral study

2023

Conference Publication

Cytokine and Mutation Profiling Reveal Patterns of Complete Remission Rates with Lenzilumab Combination Therapy in Chronic Myelomonocytic Leukemia

Kutyna, Monika, Kamel, Maha M., Ross, David M., Yong, Agnes S. M., Fong, Chun Yew, Thompson-Peach, Chloe, Lane, Steven W., Yeung, David T., Hughes, Timothy P., Hiwase, Devendra and Thomas, Daniel (2023). Cytokine and Mutation Profiling Reveal Patterns of Complete Remission Rates with Lenzilumab Combination Therapy in Chronic Myelomonocytic Leukemia. 65th ASH Annual Meeting, San Diego, CA United States, 9-12 December 2023. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2023-179706

Cytokine and Mutation Profiling Reveal Patterns of Complete Remission Rates with Lenzilumab Combination Therapy in Chronic Myelomonocytic Leukemia

2023

Conference Publication

Early Generation Telomerase Deficient Mice to Investigate Clonal Hematopoiesis in Aging

Bruedigam, Claudia, Porter, Amy H., Straube, Jasmin, Cheng, Guidan, Heidel, Florian H. and Lane, Steven W. (2023). Early Generation Telomerase Deficient Mice to Investigate Clonal Hematopoiesis in Aging. 65th ASH Annual Meeting, San Diego, CA United States, 9-12 December 2023. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2023-191246

Early Generation Telomerase Deficient Mice to Investigate Clonal Hematopoiesis in Aging

2023

Journal Article

Clearing the way for new therapies in clonal hematopoiesis

Ling, Victoria Y. and Lane, Steven W. (2023). Clearing the way for new therapies in clonal hematopoiesis. Blood Advances, 7 (22), 7151-7152. doi: 10.1182/bloodadvances.2023011728

Clearing the way for new therapies in clonal hematopoiesis

2023

Conference Publication

Excellent Early and Major Molecular Responses Observed with Asciminib Treatment for CP-CML: Results from the ALLG CML13 Ascend-CML Study

Yeung, David T., Shanmuganathan, Naranie, Reynolds, John, Branford, Susan, Walia, Mannu, Yong, Agnes S. M., Shortt, Jake, Burbury, Kate, Chee, Lynette C.Y., Viiala, Nick, Cunningham, Ilona, Ross, David M., D'Souza, Alwyn Bernard, Wright, Matthew P.F., Harrup, Rosemary Anne, Forsyth, Cecily, Filshie, Robin, Browett, Peter J., Lane, Steven W., Grove, Carolyn, Grigg, Andrew P., Hughes, Timothy P. and on Behalf Of The ALLG (2023). Excellent Early and Major Molecular Responses Observed with Asciminib Treatment for CP-CML: Results from the ALLG CML13 Ascend-CML Study. 65th ASH Annual Meeting, San Diego, CA United States, 9-12 December 2023. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2023-172583

Excellent Early and Major Molecular Responses Observed with Asciminib Treatment for CP-CML: Results from the ALLG CML13 Ascend-CML Study

2023

Journal Article

Demographic, clinical and laboratory differences between paediatric acute COVID-19 and PIMS-TS-results from a single centre study in the UK

Jiju, Prince, Matalliotakis, Michail, Lane, Steven, Wong, Waison, Hedrich, Christian M. and Pain, Clare E. (2023). Demographic, clinical and laboratory differences between paediatric acute COVID-19 and PIMS-TS-results from a single centre study in the UK. Frontiers in Pediatrics, 11 1219654, 1-11. doi: 10.3389/fped.2023.1219654

Demographic, clinical and laboratory differences between paediatric acute COVID-19 and PIMS-TS-results from a single centre study in the UK

2023

Journal Article

Genome-wide transcription factor binding maps reveal cell-specific changes in the regulatory architecture of human HSPC

Subramanian, Shruthi, Thoms, Julie A I, Huang, Yizhou, Cornejo Paramo, Carina Paola, Koch, Forrest Charles, Jacquelin, Sebastien, Shen, Sylvie, Song, Emma, Joshi, Swapna, Brownlee, Christopher Peter, Woll, Petter S., Chacon-Fajardo, Diego, Beck, Dominik, Curtis, David J, Yehson, Kenneth, Antonenas, Vicki, O'Brien, Tracey, Trickett, Annette, Powell, Jason A., Lewis, Ian D, Pitson, Stuart M, Gandhi, Maher K., Lane, Steven W, Vafaee, Fatemeh, Wong, Emily, Gottgens, Berthold, Rokny, Hamid, Wong, Jason Wing Hon and Pimanda, John E (2023). Genome-wide transcription factor binding maps reveal cell-specific changes in the regulatory architecture of human HSPC. Blood Journal, 142 (17), 1448-1462. doi: 10.1182/blood.2023021120

Genome-wide transcription factor binding maps reveal cell-specific changes in the regulatory architecture of human HSPC

2023

Journal Article

Evaluation of a novel, multicomponent anxiety management programme for people with intellectual disability: protocol for a mixed-methods, quasi-experimental feasibility study

Acton, Daniel, Williams, Jonathan, Woodrow, Ceri, Talbot, Grace, Jones, Steven, Lane, Steven and Jaydeokar, Sujeet (2023). Evaluation of a novel, multicomponent anxiety management programme for people with intellectual disability: protocol for a mixed-methods, quasi-experimental feasibility study. BMJ Open, 13 (9) e078411, 9. doi: 10.1136/bmjopen-2023-078411

Evaluation of a novel, multicomponent anxiety management programme for people with intellectual disability: protocol for a mixed-methods, quasi-experimental feasibility study

2023

Journal Article

The use of breast milk iodine concentration in the first week of lactation as a biomarker of iodine status in breast-feeding women

Liu, Shuchang, Sharp, Andrew, Luo, Xiaoqin, Lane, Steven, Villanueva, Elmer V., Lu, Zhiliang and Ma, Zheng Feei (2023). The use of breast milk iodine concentration in the first week of lactation as a biomarker of iodine status in breast-feeding women. British Journal of Nutrition, 131 (2), 286-295. doi: 10.1017/S0007114523001897

The use of breast milk iodine concentration in the first week of lactation as a biomarker of iodine status in breast-feeding women

2023

Journal Article

ACTivity as medicine In Oncology for Head and Neck (ACTIOHN): protocol for a feasibility study investigating a patient-centred approach to exercise for people with head and neck cancer

Midgley, Adrian W., Levy, Andrew R., Rogers, Simon N., Brooker, Rachel C., Bryant, Valerie, Cherry, Mary Gemma, Lane, Steven, Nugent, Michael M., Price, Ruth, Schache, Andrew G., Young, Bridget and Patterson, Joanne M. (2023). ACTivity as medicine In Oncology for Head and Neck (ACTIOHN): protocol for a feasibility study investigating a patient-centred approach to exercise for people with head and neck cancer. PLoS One, 18 (8) e0289911, 1-20. doi: 10.1371/journal.pone.0289911

ACTivity as medicine In Oncology for Head and Neck (ACTIOHN): protocol for a feasibility study investigating a patient-centred approach to exercise for people with head and neck cancer

2023

Journal Article

Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia

Eifert, Theresa, Hsu, Chen-Jen, Becker, Alicia L., Graessle, Sarah, Horne, Arik, Bemmann, Franziska, Zhang, Qirui, Heuser, Michael, Vasioukhin, Valeri, Scholl, Sebastian, Hochhaus, Andreas, Siegerist, Florian, Endlich, Nicole, Bullinger, Lars, Lane, Steven W., Haas, Simon, Schnoeder, Tina M. and Heidel, Florian H. (2023). Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia. Leukemia, 37 (10), 2027-2035. doi: 10.1038/s41375-023-02005-9

Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia

2023

Journal Article

The TRIM31-paradox: an unexpected benefit for leukemia stem cells

Straube, Jasmin and Lane, Steven W. (2023). The TRIM31-paradox: an unexpected benefit for leukemia stem cells. Haematologica, 108 (8), 1982-1983. doi: 10.3324/haematol.2022.282622

The TRIM31-paradox: an unexpected benefit for leukemia stem cells

2023

Journal Article

Follow up of women after obstetric anal sphincter injuries (OASI)-what is the role of anorectal testing?

Badri, Hawra, Fowler, Gillian and Lane, Steven (2023). Follow up of women after obstetric anal sphincter injuries (OASI)-what is the role of anorectal testing?. Neurourology and Urodynamics, 42 (6), 1374-1380. doi: 10.1002/nau.25220

Follow up of women after obstetric anal sphincter injuries (OASI)-what is the role of anorectal testing?

2023

Journal Article

Using technology to reduce critical deterioration (the DETECT study): a cost analysis of care costs at a tertiary children's hospital in the United Kingdom

Costa, Eduardo, Mateus, Ceu, Carter, Bernie, Saron, Holly, Eyton-Chong, Chin-Kien, Mehta, Fulya, Lane, Steven, Siner, Sarah, Dean, Jason, Barnes, Michael, McNally, Chris, Lambert, Caroline, Hollingsworth, Bruce, Carrol, Enitan D. D. and Sefton, Gerri (2023). Using technology to reduce critical deterioration (the DETECT study): a cost analysis of care costs at a tertiary children's hospital in the United Kingdom. BMC Health Services Research, 23 (1) 725, 1-10. doi: 10.1186/s12913-023-09739-3

Using technology to reduce critical deterioration (the DETECT study): a cost analysis of care costs at a tertiary children's hospital in the United Kingdom

2023

Journal Article

Characteristics and outcomes of patients with acute promyelocytic leukemia and extreme hyperleukocytosis at presentation

Iland, Harry J, Russell, Nigel H., Dillon, Richard, Schuh, Andre C., Tedjaseputra, Aditya, Wei, Andrew H., Khwaja, Asim, Knapper, Steven, Lane, Steven W, Reynolds, John, McMullin, Mary Frances Frances, Martin, Annalise Maria, Tan, Peter, Taussig, David Christopher C, Wong, Anny, Taper, John M, Fraga, Christina, Kelly, Richard, Tawana, Kiran, Mehta, Priyanka, Mina, Alain, Altman, Jessica K., Mølle, Ingolf, Tauro, Sudhir and Tholouli, Eleni (2023). Characteristics and outcomes of patients with acute promyelocytic leukemia and extreme hyperleukocytosis at presentation. Blood Advances, 7 (11), 2580-2585. doi: 10.1182/bloodadvances.2022007126

Characteristics and outcomes of patients with acute promyelocytic leukemia and extreme hyperleukocytosis at presentation

2023

Journal Article

Shelter from the cytokine storm in myelofibrosis

Lane, Steven W. (2023). Shelter from the cytokine storm in myelofibrosis. Blood, 141 (20), 2415-2416. doi: 10.1182/blood.2023019779

Shelter from the cytokine storm in myelofibrosis

2023

Journal Article

Could an artificial intelligence approach to prior authorization be more human?

Lenert, Leslie A., Lane, Steven and Wehbe, Ramsey (2023). Could an artificial intelligence approach to prior authorization be more human?. Journal of the American Medical Informatics Association, 30 (5), 989-994. doi: 10.1093/jamia/ocad016

Could an artificial intelligence approach to prior authorization be more human?