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2012 Journal Article Dermatophytic defensin with antiinfective potentialZhu, Shunyi, Gao, Bin, Harvey, Peta J. and Craik, David J. (2012). Dermatophytic defensin with antiinfective potential. Proceedings of the National Academy of Sciences of the United States of America, 109 (22), 8495-8500. doi: 10.1073/pnas.1201263109 |
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2012 Journal Article Delineation of the unbinding pathway of alpha-conotoxin Iml from the a7 nicotinic acetylcholine receptorYu, Rilei, Kaas, Quentin and Craik, David J. (2012). Delineation of the unbinding pathway of alpha-conotoxin Iml from the a7 nicotinic acetylcholine receptor. The Journal of Physical Chemistry B, 116 (21), 6097-6105. doi: 10.1021/jp301352d |
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2012 Journal Article Discovery and applications of naturally occurring cyclic peptidesThorstholm, L. and Craik, D. J. (2012). Discovery and applications of naturally occurring cyclic peptides. Drug Discovery Today: Technologies, 9 (1), e13-e21. doi: 10.1016/j.ddtec.2011.07.005 |
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2012 Journal Article Importance of the cell membrane on the mechanism of action of cyclotidesHenriques, Sonia Troeira and Craik, David J. (2012). Importance of the cell membrane on the mechanism of action of cyclotides. ACS Chemical Biology, 7 (4), 626-636. doi: 10.1021/cb200395f |
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2012 Journal Article Cyclization of conotoxins to improve their biopharmaceutical propertiesClark, Richard J., Akcan, Muharrem, Kaas, Quentin, Daly, Norelle L. and Craik, David J. (2012). Cyclization of conotoxins to improve their biopharmaceutical properties. Toxicon, 59 (4), 446-455. doi: 10.1016/j.toxicon.2010.12.003 |
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2012 Journal Article Cyclotides as a basis for drug designCraik, David J., Swedberg, Joakim E., Mylne, Joshua S. and Cemazar, Masa (2012). Cyclotides as a basis for drug design. Expert Opinion On Drug Discovery, 7 (3), 179-194. doi: 10.1517/17460441.2012.661554 |
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2012 Journal Article Corrigendum: Engineering of Conotoxins for the Treatment of Pain (Current Pharmaceutical Design, (2011), 17, 38)Carstens, Bodil B., Clark, Richard J., Daly, Norelle L., Harvey, Peta J., Kaas, Quentin and Craik, David J. (2012). Corrigendum: Engineering of Conotoxins for the Treatment of Pain (Current Pharmaceutical Design, (2011), 17, 38). Current Pharmaceutical Design, 18 (8) doi: 10.2174/138161212799315858 |
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2012 Journal Article Host-defense activities of cyclotidesCraik, David J. (2012). Host-defense activities of cyclotides. Toxins, 4 (2), 139-156. doi: 10.3390/toxins4020139 |
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2012 Journal Article RegIIA: An alpha 4/7-conotoxin from the venom of Conus regius that potently blocks alpha 3 beta 4 nAChRsFranco, Aldo, Kompella, Shiva N., Akondi, Kalyana B., Melaun, Christian, Daly, Norelle L., Luetje, Charles W., Alewood, Paul F., Craik, David J., Adams. David J. and Mari, Frank (2012). RegIIA: An alpha 4/7-conotoxin from the venom of Conus regius that potently blocks alpha 3 beta 4 nAChRs. Biochemical Pharmacology, 83 (3), 419-426. doi: 10.1016/j.bcp.2011.11.006 |
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2012 Journal Article Identification and structural characterization of a novel cyclotide with activity against an insect pest of sugar canePinto, Michelle F. S., Fensterseifer, Isabel C. M., Migliolo, Ludovico, Sousa, Daniel A., de Capdville, Guy, Arboleda, Jorge W., Colgrave, Michelle, Craik, David J., Magalhaes, Beatriz S., Dias, Simoni C. and Franco, Octavio L. (2012). Identification and structural characterization of a novel cyclotide with activity against an insect pest of sugar cane. The Journal of Biological Chemistry, 287 (1), 134-147. doi: 10.1074/jbc.M111.294009 |
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2012 Journal Article The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistanceAndersson, Hakan S., Figueredo, Sharel M., Haugaard-Kedstrom, Linda M., Bengtsson, Elina, Daly, Norelle L., Qu, Xiaoqing, Craik, David J., Ouellette, Andre J. and Rosengren, K. Johan (2012). The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance. Amino Acids, 43 (4), 1471-1483. doi: 10.1007/s00726-012-1220-3 |
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2012 Journal Article Engineering cyclic peptide toxinsClark, Richard J. and Craik, David J. (2012). Engineering cyclic peptide toxins. Methods in Enzymology, 503, 57-74. doi: 10.1016/B978-0-12-396962-0.00003-3 |
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2012 Journal Article Effects of Lys2 to Ala2 substitutions on the structure and potency of ω-conotoxins MVIIA and CVIDSchroeder, Christina I., Nielsen, Katherine J., Adams, Denise A., Loughnan, Marion L., Thomas, Linda, Alewood, Paul F., Lewis, Richard J. and Craik, David J. (2012). Effects of Lys2 to Ala2 substitutions on the structure and potency of ω-conotoxins MVIIA and CVID. Biopolymers, 98 (4), 345-356. doi: 10.1002/bip.22031 |
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2012 Journal Article ConoServer: updated content, knowledge, and discovery tools in the conopeptide databaseKaas, Quentin, Yu, Rilei, Jin, Ai-Hua, Dutertre, Sebastien and Craik, David J. (2012). ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research, 40 (D1), D325-D330. doi: 10.1093/nar/gkr886 |
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2011 Journal Article Engineering of conotoxins for the treatment of painCarstens, Bodil B., Clark, Richard J., Daly, Norelle L., Harvey, Peta J., Kaas, Quentin and Craik, David J. (2011). Engineering of conotoxins for the treatment of pain. Current Pharmaceutical Design, 17 (38), 4242-4253. doi: 10.2174/138161211798999401 |
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2011 Journal Article A synthetic mirror image of kalata B1 reveals that cyclotide activity is independent of a protein receptorSando, Lillian, Henriques, Sonia Troeira, Foley, Fiona, Simonsen, Shane M., Daly, Norelle L., Hall, Kristopher N., Gustafson, Kirk R., Aguilar, Marie-Isabel and Craik, David J. (2011). A synthetic mirror image of kalata B1 reveals that cyclotide activity is independent of a protein receptor. ChemBioChem, 12 (16), 2456-2462. doi: 10.1002/cbic.201100450 |
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2011 Journal Article Cyclotides: A patent reviewSmith, Amanda B., Daly, Norelle L. and Craik, David J. (2011). Cyclotides: A patent review. Expert Opinion On Therapeutic Patents, 21 (11), 1657-1672. doi: 10.1517/13543776.2011.620606 |
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2011 Journal Article Chemical Synthesis of Naturally-Occurring Cyclic Mini-Proteins from Plants and AnimalsConibear, Anne C. and Craik, David J. (2011). Chemical Synthesis of Naturally-Occurring Cyclic Mini-Proteins from Plants and Animals. Israel Journal of Chemistry, 51 (8-9), 908-916. doi: 10.1002/ijch.201100067 |
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2011 Journal Article Engineering pro-angiogenic peptides using stable disulfide-rich cyclic scaffoldsChan, Lai Y., Gunasekera, Sunithi, Henriques, Sonia T., Worth, Natalie F., Le, Sarah-Jane, Clark, Richard J., Campbell, Julie H., Craik, David J. and Daly, Norelle L. (2011). Engineering pro-angiogenic peptides using stable disulfide-rich cyclic scaffolds. Blood, 118 (25), 6709-6717. doi: 10.1182/blood-2011-06-359141 |
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2011 Journal Article Effects of cyclization on stability, structure, and activity of alpha-conotoxin RgIA at the alpha 9 alpha 10 nicotinic acetylcholine receptor and GABA(B) receptorHalai, Reena, Callaghan, Brid, Daly, Norelle L., Clark, Richard J., Adams, David J. and Craik, David J. (2011). Effects of cyclization on stability, structure, and activity of alpha-conotoxin RgIA at the alpha 9 alpha 10 nicotinic acetylcholine receptor and GABA(B) receptor. Journal of Medicinal Chemistry, 54 (19), 6984-6992. doi: 10.1021/jm201060r |
