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2011

Journal Article

α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure

Dekan, Zoltan, Vetter, Irina, Daly, Norelle L., Craik, David J., Lewis, Richard J. and Alewood, Paul F. (2011). α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure. Journal of the American Chemical Society, 133 (40), 15866-15869. doi: 10.1021/ja206408q

α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure

2011

Journal Article

Isolation and characterization of cytotoxic cyclotides from Viola philippica

He, Wenjun, Chan, Lai Yue, Zeng, Guangzhi, Daly, Norelle L., Craik, David J. and Tan, Ninghua (2011). Isolation and characterization of cytotoxic cyclotides from Viola philippica. Peptides, 32 (8), 1719-1723. doi: 10.1016/j.peptides.2011.06.016

Isolation and characterization of cytotoxic cyclotides from Viola philippica

2011

Journal Article

Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding

Dantas de Araujo, Aline, Callaghan, Brid, Nevin, Simon T., Daly, Norelle L., Craik, David J., Moretta, Melissa, Hopping, Gene, Christie, Macdonald J., Adams, David J. and Alewood, Paul F. (2011). Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding. Angewandte Chemie (International Edition), 50 (29), 6527-6529. doi: 10.1002/anie.201101642

Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding

2011

Journal Article

Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities

Henriques, Sónia Troeira, Huang, Yen-Hua, Rosengren, K. Johan, Franquelim, Henri G., Carvalho, Filomena A., Johnson, Adam, Sonza, Secondo, Tachedjian, Gilda, Castanho, Miguel A. R. B., Daly, Norelle L. and Craik, David J. (2011). Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities. Journal of Biological Chemistry, 286 (27), 24231-24241. doi: 10.1074/jbc.M111.253393

Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities

2011

Journal Article

Discovery of an unusual biosynthetic origin for circular proteins in legumes

Poth, Aaron G., Colgrave, Michelle L., Lyons, Russell E., Daly, Norelle L. and Craik, David J. (2011). Discovery of an unusual biosynthetic origin for circular proteins in legumes. Proceedings of the National Academy of Sciences of the United State of America, 108 (25), 10127-10132. doi: 10.1073/pnas.1103660108

Discovery of an unusual biosynthetic origin for circular proteins in legumes

2011

Journal Article

Structure of catalytic domain of matriptase in complex with sunflower trypsin inhibitor-1

Yuan, Cai, Chen, Liqing, Meehan, Edward J., Daly, Norelle, Craik, David J., Huang, Mingdong and Ngo, Jacky C. (2011). Structure of catalytic domain of matriptase in complex with sunflower trypsin inhibitor-1. BMC Structural Biology, 11 (30) 30, 30-1-30-10. doi: 10.1186/1472-6807-11-30

Structure of catalytic domain of matriptase in complex with sunflower trypsin inhibitor-1

2011

Journal Article

Bioactive cystine knot proteins

Daly, Norelle L. and Craik, David J. (2011). Bioactive cystine knot proteins. Current Opinion in Chemical Biology, 15 (3), 362-368. doi: 10.1016/j.cbpa.2011.02.008

Bioactive cystine knot proteins

2011

Journal Article

The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant

Wang, Conan K. L., Clark, Richard J., Harvey, Peta J., Rosengren, K. Johan, Cemazar, Masa and Craik, David J. (2011). The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant. Biochemistry, 50 (19), 4077-4086. doi: 10.1021/bi2004153

The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant

2011

Journal Article

Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3

Haugaard-Kedström, Linda M., Shabanpoor, Fazel, Hossain, Mohammed Akhter, Clark, Richard J., Ryan, Philip J., Craik, David J., Gundlach, Andrew L., Wade, John D., Bathgate, Ross A. D. and Rosengren, K. Johan (2011). Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3. Journal of the American Chemical Society, 133 (13), 4965-4974. doi: 10.1021/ja110567j

Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3

2011

Journal Article

NMR and protein structure in drug design: Application to cyclotides and conotoxins

Daly, Norelle L., Rosengren, K. Johan, Henriques, Sonia Troeira and Craik, David J. (2011). NMR and protein structure in drug design: Application to cyclotides and conotoxins. European Biophysics Journal, 40 (4), 359-370. doi: 10.1007/s00249-011-0672-9

NMR and protein structure in drug design: Application to cyclotides and conotoxins

2011

Journal Article

Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations

Yu, Rilei, Craik, David J. and Kaas, Quentin (2011). Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations. PLoS Computational Biology, 7 (3) e1002011, e1002011-1-e1002011-16. doi: 10.1371/journal.pcbi.1002011

Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations

2011

Journal Article

Understanding the structure/activity relationships of the iron regulatory peptide hepcidin

Clark, Richard J., Tan, Chia Chia, Preza, Gloria C., Nemeth, Elizabeta, Ganz, Tomas and Craik, David J. (2011). Understanding the structure/activity relationships of the iron regulatory peptide hepcidin. Chemistry and Biology, 18 (3), 336-343. doi: 10.1016/j.chembiol.2010.12.009

Understanding the structure/activity relationships of the iron regulatory peptide hepcidin

2011

Journal Article

Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels

Daly, Norelle L., Callaghan, Brid, Clark, Richard J., Nevin, Simon T., Adams, David J. and Craik, David J. (2011). Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels. Journal of Biological Chemistry, 286 (12), 10233-10237. doi: 10.1074/jbc.M110.196170

Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels

2011

Journal Article

ChemInform Abstract: Naturally Occurring Circular Proteins: Distribution, Biosynthesis and Evolution

Cascales, Laura and Craik, David J. (2011). ChemInform Abstract: Naturally Occurring Circular Proteins: Distribution, Biosynthesis and Evolution. ChemInform, 42 (9). doi: 10.1002/chin.201109276

ChemInform Abstract: Naturally Occurring Circular Proteins: Distribution, Biosynthesis and Evolution

2011

Journal Article

Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy

Akcan, M, Stroud, MR, Hansen, SJ, Clark, RJ, Daly, NL, Craik, DJ and Olson, JM (2011). Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy. Journal of Medicinal Chemistry, 54 (3), 782-787. doi: 10.1021/jm101018r

Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy

2011

Journal Article

The folding of disulfide-rich proteins

Craik, David J. (2011). The folding of disulfide-rich proteins. Antioxidants and Redox Signaling, 14 (1), 61-64. doi: 10.1089/ars.2010.3656

The folding of disulfide-rich proteins

2011

Journal Article

Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptides

Cascales, Laura, Henriques, Sónia T., Kerr, Markus C., Huang, Yen-Hua, Sweet, Matthew J., Daly, Norelle L. and Craik, David J. (2011). Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptides. Journal of Biological Chemistry, Epub ahead of print (42), 36932-36943. doi: 10.1074/jbc.M111.264424

Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptides

2011

Journal Article

Interlocking Disulfides in Circular Proteins: Toward Efficient Oxidative Folding of Cyclotides

Aboye, Teshome Leta, Clark, Richard J., Burman, Robert, Roig, Marta Bajona, Craik, David J. and Goransson, Ulf (2011). Interlocking Disulfides in Circular Proteins: Toward Efficient Oxidative Folding of Cyclotides. Antioxidants & Redox Signaling, 14 (1), 77-86. doi: 10.1089/ars.2010.3112

Interlocking Disulfides in Circular Proteins: Toward Efficient Oxidative Folding of Cyclotides

2011

Journal Article

Conopeptides as novel options for pain management

Daly, N. L. and Craik, David J. (2011). Conopeptides as novel options for pain management. Drugs of the Future, 36 (1), 25-32. doi: 10.1358/dof.2011.36.1.1561066

Conopeptides as novel options for pain management

2011

Journal Article

Stabilization of α-conotoxin AuIB: Influences of disulfide connectivity and backbone cyclization

Lovelace, Erica S., Gunasekera, Sunithi, Alvarmo, Charlotta, Clark, Richard J., Nevin, Simon T., Grishin, Anton A., Adams, David J., Craik, David J. and Daly, Norelle L. (2011). Stabilization of α-conotoxin AuIB: Influences of disulfide connectivity and backbone cyclization. Antioxidants and Redox Signaling, 14 (1), 87-95. doi: 10.1089/ars.2009.3068

Stabilization of α-conotoxin AuIB: Influences of disulfide connectivity and backbone cyclization