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2021

Conference Publication

An N-capping asparagine-lysine-proline (NKP) motif contributes to a hybrid flexible/stable multifunctional peptide scaffold

Silva Cardoso, Marlon Henrique E., Chan, Lai Yue, Candido, Elizabete De Souza, Torres, Marcelo D. T., Oshiro, Karen G. N., Silva, Itala C., Goncalves, S., Buccini, Danieli Fernanda, Lu, Timothy K., Santos, Nuno C., De la Fuente-Nunez, Cesar, Craik, David J. and Franco, Octavio L. (2021). An N-capping asparagine-lysine-proline (NKP) motif contributes to a hybrid flexible/stable multifunctional peptide scaffold. 20th IUPAB International Congress, 45th SBBf Congress and 50th Annual Meeting of SBBq, Online, 4-8 October 2021. London, United Kingdom: Springer.

An N-capping asparagine-lysine-proline (NKP) motif contributes to a hybrid flexible/stable multifunctional peptide scaffold

2020

Conference Publication

The insecticidal wasp toxin Γ–Pompilidotoxin is a linear peptide modulating voltage-gated sodium channels

Peigneur, Steve, Tsarev, Andrey V., Paramonov, Alexander S., Schroeder, Christina I., Ikonomopoulou, Maria P., Inagaki, Hidetoshi, Craik, David J., Konno, Katsuhiro, Shenkarev, Zakhar O. and Tytgat, Jan (2020). The insecticidal wasp toxin Γ–Pompilidotoxin is a linear peptide modulating voltage-gated sodium channels. 20th World Congress of the International Society on Toxinology, Buenos Aires, Argentina, 8-13 September 2019. Oxford, United Kingdom: Elsevier.

The insecticidal wasp toxin Γ–Pompilidotoxin is a linear peptide modulating voltage-gated sodium channels

2020

Conference Publication

Challenging the chirality paradigm in peptide-lipid interactions

Henriques, Sonia Troeira, Peacock, Hayden, Benfield, Aurelie H., Wang, Conan K. and Craik, David (2020). Challenging the chirality paradigm in peptide-lipid interactions. 64th Annual Meeting of the Biophysical Society, San Diego, CA, United States, 15-19 February 2020. St. Louis, MO, United States: Cell Press. doi: 10.1016/j.bpj.2019.11.1983

Challenging the chirality paradigm in peptide-lipid interactions

2019

Conference Publication

Spider toxins as novel allosteric modulators of insect nicotinic receptors

Earley, Fergus, Chambers, Chris, Cutler, Penny, Huang, Yen-Hua and Craik, David (2019). Spider toxins as novel allosteric modulators of insect nicotinic receptors. ACS Fall National Meeting and Exposition, San Diego, CA, United States, 25-29 August, 2019. Washington, DC United States: American Chemical Society.

Spider toxins as novel allosteric modulators of insect nicotinic receptors

2018

Conference Publication

Topologically complex peptides from plants as tools for the development of eco-friendly drugs and agrichemicals

Craik, David (2018). Topologically complex peptides from plants as tools for the development of eco-friendly drugs and agrichemicals. 255th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nexus of Food, Energy, and Water, New Orleans La, Mar 18-22, 2018. WASHINGTON: AMER CHEMICAL SOC.

Topologically complex peptides from plants as tools for the development of eco-friendly drugs and agrichemicals

2018

Conference Publication

A journey alongside cyclosporin on the road to peptide oral bioavailability

Wang, Conan and Craik, David (2018). A journey alongside cyclosporin on the road to peptide oral bioavailability. 35th European Peptide Symposium, Dublin City University, Ireland, 26-31 August 2018. Oxford, United Kingdom: John Wiley & Sons.

A journey alongside cyclosporin on the road to peptide oral bioavailability

2018

Conference Publication

Targeting the coiled-coil domain of BCR-ABL1 kinase with new weapons

Huang, Yen-Hua, Passioura, Toby, Peacock, Hayden, Henriques, Sonia Troeira, Wang, Conan, Kaas, Quentin, Suga, Hiroaki and Craik, David (2018). Targeting the coiled-coil domain of BCR-ABL1 kinase with new weapons. 35th European Peptide Symposium, Dublin City University, Ireland, 26-31 August 2018. Oxford, United Kingdom: John Wiley & Sons.

Targeting the coiled-coil domain of BCR-ABL1 kinase with new weapons

2018

Conference Publication

The use of peptide-membrane interactions in the design of selective and potent sodium channel inhibitors

Schroeder, Christina, Agwa, Akello, Mueller, Alexander, Chow, Chun Yuen, Peigneur, Steve, Lawrence, Nicole, Deplazes, Evelyne, Mark, Alan, Craik, David, Tytgat, Jan, King, Glenn, Vetter, Irina and Henriques, Sonia Troeira (2018). The use of peptide-membrane interactions in the design of selective and potent sodium channel inhibitors. 35th European Peptide Symposium, Dublin City University, Ireland, 26-31 August 2018. Oxford, United Kingdom: John Wiley & Sons.

The use of peptide-membrane interactions in the design of selective and potent sodium channel inhibitors

2018

Conference Publication

Mechanisms of bacterial membrane permeabilization of snake venom-derived peptides crotalicidin (Ctn) and Ctn[15-34]

Perez-Peinado, Clara, Almeida Dias, Susana, Domingues, Marco M., Benfield, Aurelie H., Miguel Freire, Jodo, Radis-Baptista, Gandhi, Gaspar, Diana, Castanho, Miguel, Craik, David, Henriques, Sonia Troeira, Salome Veiga, Ana and Andreu, David (2018). Mechanisms of bacterial membrane permeabilization of snake venom-derived peptides crotalicidin (Ctn) and Ctn[15-34]. 35th European Peptide Symposium, Dublin City University, Ireland, 26-31 August 2018. Oxford, United Kingdom: John Wiley & Sons .

Mechanisms of bacterial membrane permeabilization of snake venom-derived peptides crotalicidin (Ctn) and Ctn[15-34]

2018

Conference Publication

Is the mirror image a true reflection? Lipid chirality in the activity of the prototypic cyclotide kalata B1

Henriques, Sonia Troeira, Peacock, Hayden, Benfield, Aurelie H., Wang, Conan and Craik, David (2018). Is the mirror image a true reflection? Lipid chirality in the activity of the prototypic cyclotide kalata B1. 35th European Peptide Symposium, Dublin City University, Ireland, 26-31 August 2018. Oxford, United Kingdom: John Wiley & Sons.

Is the mirror image a true reflection? Lipid chirality in the activity of the prototypic cyclotide kalata B1

2018

Conference Publication

Development of serine protease inhibitors using the 1,2,3-triazole motif as a disulfide mimetic in the cyclic peptide sunflower trypsin inhibitor-1

White, Andrew, Deveer, Simon, Swedberg, Joakim, Durek, Thomas and Craik, David (2018). Development of serine protease inhibitors using the 1,2,3-triazole motif as a disulfide mimetic in the cyclic peptide sunflower trypsin inhibitor-1. 35th European Peptide Symposium, Dublin City University, Ireland, 26-31 August 2018. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.3127

Development of serine protease inhibitors using the 1,2,3-triazole motif as a disulfide mimetic in the cyclic peptide sunflower trypsin inhibitor-1

2018

Conference Publication

Inhibition of nicotinic acetylcholine receptor subtypes by the ribbon isomers of alpha-conotoxins

Kaas, Quentin, Wu, Xiaosa, Tae, Han-Shen, Huang, Yen-Hua, Adams, David J. and Craik, David (2018). Inhibition of nicotinic acetylcholine receptor subtypes by the ribbon isomers of alpha-conotoxins. 35th European Peptide Symposium, Dublin City University, Ireland, 26-31 August 2018. Oxford, United Kingdom: John Wiley & Sons.

Inhibition of nicotinic acetylcholine receptor subtypes by the ribbon isomers of alpha-conotoxins

2017

Conference Publication

Small molecule and peptidic ligands as PCSK9-LDLR inhibitors

Bhattacharya, Samit, Ammirati, Mark, Borzilleri, Kris, Cheneval, Olivier, Chrunyk, Boris, Craik, David, Daly, Norelle, Dullea, Robert, Griffor, Matthew, Kamlet, Adam, Limberakis, Chris, Sahasrabudhe, Parag, Liu, Shenping, Loria, Paula, Mc Clure, Kim, Menhaji-Klotz, Elnaz, Petersen, Donna, Piotrowski, David, Popovska-Gorevski, Marina, Price, David, Reyes, Allan, Ruggeri, Roger, Schroeder, Christina, Song, Kun, Swedberg, Joakim, Stock, Ingrid, Tu, Meihua and Withka, Jane (2017). Small molecule and peptidic ligands as PCSK9-LDLR inhibitors. 254th National Meeting and Exposition of the American-Chemical-Society (ACS) on Chemistry's Impact on the Global Economy, Washington, DC, 20-24 August 2017 . Washington, DC, United States: American Chemical Society.

Small molecule and peptidic ligands as PCSK9-LDLR inhibitors

2016

Conference Publication

Miniaturised Alpha-Conotoxins for the Treatment of Pain

Carstens, B., Berecki, G., Daniel, J., Lee, H. S., Jackson, K., Tae, H-S., Sadeghi, M., Castro, J., O'Donnell, T., Deiteren, A., Brierley, S., Craik, D., Adams, D. and Clark, R. (2016). Miniaturised Alpha-Conotoxins for the Treatment of Pain. 247th National Spring Meeting of the American-Chemical-Society (ACS), Dallas Tx, Mar 16-20, 2014. HOBOKEN: WILEY.

Miniaturised Alpha-Conotoxins for the Treatment of Pain

2016

Conference Publication

Towards An Understanding of A- Conotoxin Receptor Specificity

Kaas, Q. and Craik, D. J. (2016). Towards An Understanding of A- Conotoxin Receptor Specificity. HOBOKEN: Wiley.

Towards An Understanding of A- Conotoxin Receptor Specificity

2016

Conference Publication

Modulation of colonic sensory signaling by novel alpha-conotoxin Vc1.1 analogues in mice

Deiteren, A., Castro, J., O'Donnell, T., Craik, D. J., Adams, D. J. and Brierley, S. M. (2016). Modulation of colonic sensory signaling by novel alpha-conotoxin Vc1.1 analogues in mice. 2nd Federation of Neurogastroenterology and Motility Meeting, San Francisco, California, United States, 25-28 August, 2016. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/nmo.12881

Modulation of colonic sensory signaling by novel alpha-conotoxin Vc1.1 analogues in mice

2016

Conference Publication

Structure-Activity Relationship Studies Reveal that the Spider Toxin Protx-II has Unusual Membrane-Binding Properties and Inhibits NAV1.7 Channel at the Membrane Surface

Henriques, Sonia Troeira, Craik, David J. and Schroeder, Christina I. (2016). Structure-Activity Relationship Studies Reveal that the Spider Toxin Protx-II has Unusual Membrane-Binding Properties and Inhibits NAV1.7 Channel at the Membrane Surface. 60th Annual Meeting of the Biophysical-Society, Los Angeles, CA, United States, Feb 27-Mar 02, 2016. CAMBRIDGE: CELL PRESS.

Structure-Activity Relationship Studies Reveal that the Spider Toxin Protx-II has Unusual Membrane-Binding Properties and Inhibits NAV1.7 Channel at the Membrane Surface

2016

Conference Publication

Design and plant-based production of therapeutic cyclic peptides

Craik, D., Oguis, G. K., Smithies, B., Qu, H., Gilding, E. K. and Jackson, M. A. (2016). Design and plant-based production of therapeutic cyclic peptides. 34th European Peptide Symposium, Leipzig, Germany, 4‐9 September 2016. Oxford, United Kingdom: John Wiley & Sons.

Design and plant-based production of therapeutic cyclic peptides

2016

Conference Publication

Membrane-binding properties of gating-modifier and pore blocking toxins: membrane interaction is not a prerequisite for modification of channel gating

Deplazes, Evelyne, Henriques, Sonia Troeira, King, Glenn F., Craik, David J., Mark, Alan E. and Schroeder, Christina I. (2016). Membrane-binding properties of gating-modifier and pore blocking toxins: membrane interaction is not a prerequisite for modification of channel gating. 60th Annual Meeting of the Biophysical-Society, Los Angeles, United States, February 27- March 2 2016. St Louis, United States: Cell Press. doi: 10.1016/j.bpj.2015.11.220

Membrane-binding properties of gating-modifier and pore blocking toxins: membrane interaction is not a prerequisite for modification of channel gating

2016

Conference Publication

Cyclotides, stable drug scaffolds and delivery systems to target intracellular cancer pathways

Henriques, S. Troeira, Huang, Y. -H. and Craik, D. (2016). Cyclotides, stable drug scaffolds and delivery systems to target intracellular cancer pathways. 34th European Peptide Symposium, Leipzig, Germany, 4-9 September 2016. Oxford, United Kingdom: John Wiley & Sons.

Cyclotides, stable drug scaffolds and delivery systems to target intracellular cancer pathways