|
2023 Journal Article The circular bacteriocin enterocin NKR-5-3B has an improved stability profile over nisinWang, Conan K., Huang, Yen-Hua, Shabbir, Fatima, Pham, Huong T., Lawrence, Nicole, Benfield, Aurélie H., van der Donk, Wilfred, Henriques, Sónia T., Turner, Mark S. and Craik, David J. (2023). The circular bacteriocin enterocin NKR-5-3B has an improved stability profile over nisin. Peptides, 167 171049, 171049. doi: 10.1016/j.peptides.2023.171049 |
|
2023 Journal Article A chemoenzymatic approach to produce a cyclic analogue of the analgesic drug MVIIA (Ziconotide)Zhou, Yan, Harvey, Peta J., Koehbach, Johannes, Chan, Lai Yue, Jones, Alun, Andersson, Åsa, Vetter, Irina, Durek, Thomas and Craik, David J. (2023). A chemoenzymatic approach to produce a cyclic analogue of the analgesic drug MVIIA (Ziconotide). Angewandte Chemie, 135 (29) e202302812, 1-5. doi: 10.1002/ange.202302812 |
|
2023 Journal Article Captivity induces a sweeping and sustained genomic response in a starfishMorin, Marie, Jönsson, Mathias, Wang, Conan K., Craik, David J., Degnan, Sandie M. and Degnan, Bernard M. (2023). Captivity induces a sweeping and sustained genomic response in a starfish. Molecular Ecology, 32 (13), 3541-3556. doi: 10.1111/mec.16947 |
|
2023 Journal Article Development of antiplasmodial peptide–drug conjugates using a human protein-derived cell-penetrating peptide with selectivity for infected cellsPalombi, Isabella R., Lawrence, Nicole, White, Andrew M., Gare, Caitlin L., Craik, David J., McMorran, Brendan J. and Malins, Lara R. (2023). Development of antiplasmodial peptide–drug conjugates using a human protein-derived cell-penetrating peptide with selectivity for infected cells. Bioconjugate Chemistry, 34 (6), 1105-1113. doi: 10.1021/acs.bioconjchem.3c00147 |
|
2023 Journal Article A chemo-enzymatic approach to produce a cyclic analogue of the analgesic drug MVIIA (Ziconotide)Zhou, Yan, Harvey, Peta J., Koehbach, Johannes, Chan, Lai Yue, Jones, Alun, Andersson, Åsa, Vetter, Irina, Durek, Thomas and Craik, David J. (2023). A chemo-enzymatic approach to produce a cyclic analogue of the analgesic drug MVIIA (Ziconotide). Angewandte Chemie, 62 (29) e202302812, e202302812. doi: 10.1002/anie.202302812 |
|
2023 Journal Article Nematicidal activity of cyclotides: toxicity against Caenorhabditis elegansBajpai, Abhishek, Jackson, Mark A., Huang, Yen-Hua, Yap, Kuok, Du, Qingdan, Chau, Tevin Chui-Ying, Craik, David J. and Gilding, Edward K. (2023). Nematicidal activity of cyclotides: toxicity against Caenorhabditis elegans. Journal of Natural Products, 86 (5), 1222-1229. doi: 10.1021/acs.jnatprod.2c01124 |
|
2023 Journal Article Plant-based production of an orally active cyclotide for the treatment of multiple sclerosisJackson, Mark A., Xie, Jing, Nguyen, Linh T. T., Wang, Xiaohan, Yap, Kuok, Harvey, Peta J., Gilding, Edward K. and Craik, David J. (2023). Plant-based production of an orally active cyclotide for the treatment of multiple sclerosis. Transgenic Research, 32 (1-2), 121-133. doi: 10.1007/s11248-023-00341-1 |
|
2022 Journal Article Peptide-based LDH5 inhibitors enter cancer cells and impair proliferationNadal-Bufí, Ferran, Chan, Lai Y., Mohammad, Hadi H., Mason, Jody M., Salomon, Carlos, Lai, Andrew, Thompson, Erik W., Craik, David J., Kaas, Quentin and Henriques, Sónia T. (2022). Peptide-based LDH5 inhibitors enter cancer cells and impair proliferation. Cellular and Molecular Life Sciences, 79 (12) 606, 606. doi: 10.1007/s00018-022-04633-3 |
|
2022 Journal Article Engineering the cyclization loop of MCoTI-II generates targeted cyclotides that potently inhibit factor XIIaTian, Sixin, Durek, Thomas, Wang, Conan K., Zdenek, Christina N., Fry, Bryan G., Craik, David J. and de Veer, Simon J. (2022). Engineering the cyclization loop of MCoTI-II generates targeted cyclotides that potently inhibit factor XIIa. Journal of Medicinal Chemistry, 65 (23), 15698-15709. doi: 10.1021/acs.jmedchem.2c01080 |
|
2022 Journal Article Rational domestication of a plant-based recombinant expression system expands its biosynthetic rangeJackson, Mark A., Chan, Lai Yue , Harding, Maxim D., Craik, David J. and Gilding, Edward K. (2022). Rational domestication of a plant-based recombinant expression system expands its biosynthetic range. Journal of Experimental Botany, 73 (18), 6103-6114. doi: 10.1093/jxb/erac273 |
|
2022 Journal Article Improving stability enhances in vivo efficacy of a PCSK9 inhibitory peptideZhang, Yuhui, Wang, Li, Tombling, Benjamin J., Lammi, Carmen, Huang, Yen-Hua, Li, Yue, Bartolomei, Martina, Hong, Bin, Craik, David J. and Wang, Conan K. (2022). Improving stability enhances in vivo efficacy of a PCSK9 inhibitory peptide. Journal of the American Chemical Society, 144 (42), 19485-19498. doi: 10.1021/jacs.2c08029 |
|
2022 Journal Article The acyclotide ribe 31 from Rinorea bengalensis has selective cytotoxicity and potent insecticidal properties in DrosophilaDang, Tien T., Huang, Yen-Hua, Ott, Stanislav, Harvey, Peta J., Gilding, Edward K., Tombling, Benjamin J., Chan, Lai Y., Kaas, Quentin, Claridge-Chang, Adam and Craik, David J. (2022). The acyclotide ribe 31 from Rinorea bengalensis has selective cytotoxicity and potent insecticidal properties in Drosophila. Journal of Biological Chemistry, 298 (10) 102413, 1-11. doi: 10.1016/j.jbc.2022.102413 |
|
2022 Journal Article Late-stage functionalization with cysteine staples generates potent and selective melanocortin receptor-1 agonistsWhite, Andrew M., Dellsén, Anita, Larsson, Niklas, Kaas, Quentin, Jansen, Frank, Plowright, Alleyn T., Knerr, Laurent, Durek, Thomas and Craik, David J. (2022). Late-stage functionalization with cysteine staples generates potent and selective melanocortin receptor-1 agonists. Journal of Medicinal Chemistry, 65 (19), 12956-12969. doi: 10.1021/acs.jmedchem.2c00793 |
|
2022 Journal Article Accurate de novo design of membrane-traversing macrocyclesBhardwaj, Gaurav, O’Connor, Jacob, Rettie, Stephen, Huang, Yen-Hua, Ramelot, Theresa A., Mulligan, Vikram Khipple, Alpkilic, Gizem Gokce, Palmer, Jonathan, Bera, Asim K., Bick, Matthew J., Di Piazza, Maddalena, Li, Xinting, Hosseinzadeh, Parisa, Craven, Timothy W., Tejero, Roberto, Lauko, Anna, Choi, Ryan, Glynn, Calina, Dong, Linlin, Griffin, Robert, van Voorhis, Wesley C., Rodriguez, Jose, Stewart, Lance, Montelione, Gaetano T., Craik, David and Baker, David (2022). Accurate de novo design of membrane-traversing macrocycles. Cell, 185 (19), 3520-3532.e26. doi: 10.1016/j.cell.2022.07.019 |
|
2022 Journal Article CIPPS, an Australian Centre for Peptide and Protein Research, goes live!Wang, Conan K. and Craik, David J. (2022). CIPPS, an Australian Centre for Peptide and Protein Research, goes live!. Peptides, 155 170835, 1-2. doi: 10.1016/j.peptides.2022.170835 |
|
2022 Journal Article Mutagenesis of bracelet cyclotide hyen D reveals functionally and structurally critical residues for membrane binding and cytotoxicityDu, Qingdan, Huang, Yen-Hua, Wang, Conan K., Kaas, Quentin and Craik, David J. (2022). Mutagenesis of bracelet cyclotide hyen D reveals functionally and structurally critical residues for membrane binding and cytotoxicity. Journal of Biological Chemistry, 298 (4) 101822, 101822. doi: 10.1016/j.jbc.2022.101822 |
|
2022 Journal Article Comparative analysis of cyclotide-producing plant cell suspensions presents opportunities for cyclotide plant molecular farmingDoffek, Benjamin, Huang, Yvonne, Huang, Yen-Hua, Chan, Lai Yue, Gilding, Edward K., Jackson, Mark A. and Craik, David J. (2022). Comparative analysis of cyclotide-producing plant cell suspensions presents opportunities for cyclotide plant molecular farming. Phytochemistry, 195 113053, 1-10. doi: 10.1016/j.phytochem.2021.113053 |
|
2022 Journal Article Enzymatic C‐to‐C Protein LigationRehm, Fabian B. H., Tyler, Tristan J., Veer, Simon J., Craik, David J. and Durek, Thomas (2022). Enzymatic C‐to‐C Protein Ligation. Angewandte Chemie International Edition, 134 (11) e202116672, e202116672. doi: 10.1002/anie.202116672 |
|
2022 Journal Article Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation systemWu, Yue, Cui, Zhenling, Huang, Yen-Hua, de Veer, Simon J., Aralov, Andrey V., Guo, Zhong, Moradi, Shayli V., Hinton, Alexandra O., Deuis, Jennifer R., Guo, Shaodong, Chen, Kai-En, Collins, Brett M., Vetter, Irina, Herzig, Volker, Jones, Alun, Cooper, Matthew A., King, Glenn F., Craik, David J., Alexandrov, Kirill and Mureev, Sergey (2022). Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system. Nature Communications, 13 (1) 260, 260. doi: 10.1038/s41467-021-27854-9 |
|
2021 Journal Article Modified horseshoe crab peptides target and kill bacteria inside host cellsAmiss, Anna S., von Pein, Jessica B., Webb, Jessica R., Condon, Nicholas D., Harvey, Peta J., Phan, Minh-Duy, Schembri, Mark A., Currie, Bart J., Sweet, Matthew J., Craik, David J., Kapetanovic, Ronan, Henriques, Sónia Troeira and Lawrence, Nicole (2021). Modified horseshoe crab peptides target and kill bacteria inside host cells. Cellular and Molecular Life Sciences, 79 (1) 38, 38. doi: 10.1007/s00018-021-04041-z |
