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2014 Journal Article Molecular grafting onto a stable framework yields novel cyclic peptides for the treatment of multiple sclerosisWang, Conan K., Gruber, Christian W., Cemazar, Masa, Siatskas, Christopher, Tagore, Prascilla, Payne, Natalie, Sun, Guizhi, Wang, Shunhe, Bernard, Claude C. and Craik, David J. (2014). Molecular grafting onto a stable framework yields novel cyclic peptides for the treatment of multiple sclerosis. ACS Chemical Biology, 9 (1), 156-163. doi: 10.1021/cb400548s |
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2013 Journal Article The Future of Peptide-based DrugsCraik, David J., Fairlie, David P., Liras, Spiros and Price, David (2013). The Future of Peptide-based Drugs. Chemical Biology and Drug Design, 81 (1), 136-147. doi: 10.1111/cbdd.12055 |
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2012 Journal Article Protein folding: Turbo-charged crosslinkingCraik, David J. (2012). Protein folding: Turbo-charged crosslinking. Nature Chemistry, 4 (8), 600-602. doi: 10.1038/nchem.1417 |
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2012 Journal Article Cyclotides associate with leaf vasculature and are the products of a novel precursor in Petunia (Solanaceae)Poth, Aaron G., Mylne, Joshua S., Grassl, Julia, Lyons, Russell E., Millar, A. Harvey, Colgrave, Michelle L. and Craik, David J. (2012). Cyclotides associate with leaf vasculature and are the products of a novel precursor in Petunia (Solanaceae). Journal of Biological Chemistry, 287 (32), 27033-27046. doi: 10.1074/jbc.M112.370841 |
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2011 Journal Article The chemistry of cyclotidesCraik, David J. and Conibear, Anne C. (2011). The chemistry of cyclotides. Journal of Organic Chemistry, 76 (12), 4805-4817. doi: 10.1021/jo200520v |
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2011 Journal Article Albumins and their processing machinery are hijacked for cyclic peptides in sunflowerMylne, Joshua S., Colgrave, Michelle L., Daly, Norelle L., Chanson, Aurelie H., Elliott, Alysha G., McCallum, Emily J., Jones, Alun and Craik, David J. (2011). Albumins and their processing machinery are hijacked for cyclic peptides in sunflower. Nature Chemical Biology, 7 (5), 257-259. doi: 10.1038/nchembio.542 |
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2011 Journal Article Discovery of cyclotides in the Fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteinsPoth, Aaron G., Colgrave, Michelle L., Philip, Reynold, Kerenga, Bomai, Daly, Norelle L., Anderson, Marilyn A. and Craik, David J. (2011). Discovery of cyclotides in the Fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins. ACS Chemical Biology, 6 (4), 345-355. doi: 10.1021/cb100388j |
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2009 Journal Article Circling the enemy: cyclic proteins in plant defenceCraik, David J. (2009). Circling the enemy: cyclic proteins in plant defence. Trends in Plant Science, 14 (6), 328-335. doi: 10.1016/j.tplants.2009.03.003 |
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2009 Journal Article Conotoxins: natural product drug leadsHalai, Reena and Craik, David J. (2009). Conotoxins: natural product drug leads. Natural Product Reports, 26 (4), 526-536. doi: 10.1039/b819311h |
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2008 Journal Article Distribution and evolution of circular miniproteins in flowering plantsGruber, Christian W., Elliott, Alysha G., Ireland, David C., Delprete, Piero G., Dessein, Steven, Goransson, Ulf, Trabi, Manuela, Wang, Conan K., Kinghorn, Andrew B., Robbrecht, Elmar and Craik, David J. (2008). Distribution and evolution of circular miniproteins in flowering plants. The Plant Cell, 20 (9), 2471-2483. doi: 10.1105/tpc.108.062331 |
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2006 Journal Article Chemistry - Seamless proteins tie up their loose endsCraik, D. J. (2006). Chemistry - Seamless proteins tie up their loose ends. Science, 311 (5767), 1563-1564. doi: 10.1126/science.1125248 |
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2025 Journal Article Cell-penetrating cyclic and disulfide-rich peptides are privileged molecular scaffolds for intracellular targetingTroeira Henriques, Sónia, Lawrence, Nicole, Kan, Meng-Wei, Malins, Lara R. and Craik, David J. (2025). Cell-penetrating cyclic and disulfide-rich peptides are privileged molecular scaffolds for intracellular targeting. Biochemistry, 64 (7), 1437-1449. doi: 10.1021/acs.biochem.4c00845 |
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2025 Journal Article The future of utilising semiochemical pest control methods to manage the destructive crown-of-thorns starfish outbreaks on coral reefsHarris, Richard J., Barnard, d'Artagnan L., Paxton, Gillian, Lockie, Stewart, Craik, David J., Cummins, Scott F., Wang, Conan K. and Motti, Cherie A. (2025). The future of utilising semiochemical pest control methods to manage the destructive crown-of-thorns starfish outbreaks on coral reefs. Biological Conservation, 302 110984, 110984-302. doi: 10.1016/j.biocon.2025.110984 |
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2025 Journal Article Exploring the utility of cell-penetrating peptides as vehicles for the delivery of distinct antimalarial drug cargoesGare, Caitlin L., Palombi, Isabella R., White, Andrew M., Chavchich, Marina, Edstein, Michael D., Lock, Aaron, Avery, Vicky M., Craik, David J., McMorran, Brendan J., Lawrence, Nicole and Malins, Lara Rebecca (2025). Exploring the utility of cell-penetrating peptides as vehicles for the delivery of distinct antimalarial drug cargoes. ChemMedChem, 20 (2) e202400637. doi: 10.1002/cmdc.202400637 |
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2025 Journal Article Synthesis and Investigation of Peptide-Drug Conjugates Comprising Camptothecin and a Human Protein-Derived Cell-Penetrating PeptidePalombi, Isabella R., White, Andrew M., Koda, Yasuko, Craik, David J., Lawrence, Nicole and Malins, Lara R. (2025). Synthesis and Investigation of Peptide-Drug Conjugates Comprising Camptothecin and a Human Protein-Derived Cell-Penetrating Peptide. Chemical Biology & Drug Design, 105 (1) e70051, 1-10. doi: 10.1111/cbdd.70051 |
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2025 Journal Article Analogs of cyclic peptide mortiamide‐d from marine fungi have improved membrane permeability and kill drug‐resistant melanoma cellsBergeron, Catherine, Bérubé, Christopher, Lamb, Henry, Koda, Yasuko, Craik, David J., Henriques, Sónia Troeira, Voyer, Normand and Lawrence, Nicole (2025). Analogs of cyclic peptide mortiamide‐d from marine fungi have improved membrane permeability and kill drug‐resistant melanoma cells. Peptide Science, 117 (1) e24380. doi: 10.1002/pep2.24380 |
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2024 Journal Article Highly Efficient Transpeptidase-Catalyzed Isopeptide Ligationde Veer, Simon J., Craik, David J. and Rehm, Fabian B. H. (2024). Highly Efficient Transpeptidase-Catalyzed Isopeptide Ligation. Journal of the American Chemical Society, 147 (1), 557-565. doi: 10.1021/jacs.4c11964 |
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2024 Journal Article Peptide PaDBS1R6 has potent antibacterial activity on clinical bacterial isolates and integrates an immunomodulatory peptide fragment within its sequenceRezende, Samilla B., Chan, Lai Yue, Oshiro, Karen G.N., Buccini, Danieli F., Leal, Ana Paula Ferreira, Ribeiro, Camila F., Souza, Carolina M., Brandão, Amanda L.O., Gonçalves, Regina M., Cândido, Elizabete S., Macedo, Maria L.R., Craik, David J., Franco, Octávio L. and Cardoso, Marlon H. (2024). Peptide PaDBS1R6 has potent antibacterial activity on clinical bacterial isolates and integrates an immunomodulatory peptide fragment within its sequence. Biochimica et Biophysica Acta (BBA) - General Subjects, 1868 (11) 130693, 130693. doi: 10.1016/j.bbagen.2024.130693 |
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2024 Journal Article Discovery of five classes of bacterial defensins: ancestral precursors of defensins from eukarya?Cardoso, Marlon H., de Lima, Lucas R., Pires, Allan S., Maximiano, Mariana R., Harvey, Peta J., Freitas, Camila G., Costa, Rosiane A., Fensterseifer, Isabel C. M., Rigueiras, Pietra O., Migliolo, Ludovico, Porto, William F., Craik, David J. and Franco, Octávio L. (2024). Discovery of five classes of bacterial defensins: ancestral precursors of defensins from eukarya?. ACS Omega, 9 (45), 45297-45308. doi: 10.1021/acsomega.4c06956 |
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2024 Journal Article Gene-guided identifications of a structure-chimeric cyclotide viphi I from Viola philippica: potential functions against cadmium and nematodesZhang, Xiaojie, Chen, Ruohong, Shu, Haoyue, Liang, Peihui, Qin, Ting, Wang, Kemei, Guo, Aimin, Craik, David J., Liao, Bin and Zhang, Jun (2024). Gene-guided identifications of a structure-chimeric cyclotide viphi I from Viola philippica: potential functions against cadmium and nematodes. Plant Science, 347 112185. doi: 10.1016/j.plantsci.2024.112185 |
