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2014 Journal Article Molecular grafting onto a stable framework yields novel cyclic peptides for the treatment of multiple sclerosisWang, Conan K., Gruber, Christian W., Cemazar, Masa, Siatskas, Christopher, Tagore, Prascilla, Payne, Natalie, Sun, Guizhi, Wang, Shunhe, Bernard, Claude C. and Craik, David J. (2014). Molecular grafting onto a stable framework yields novel cyclic peptides for the treatment of multiple sclerosis. ACS Chemical Biology, 9 (1), 156-163. doi: 10.1021/cb400548s |
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2013 Journal Article The Future of Peptide-based DrugsCraik, David J., Fairlie, David P., Liras, Spiros and Price, David (2013). The Future of Peptide-based Drugs. Chemical Biology and Drug Design, 81 (1), 136-147. doi: 10.1111/cbdd.12055 |
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2012 Journal Article Protein folding: Turbo-charged crosslinkingCraik, David J. (2012). Protein folding: Turbo-charged crosslinking. Nature Chemistry, 4 (8), 600-602. doi: 10.1038/nchem.1417 |
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2012 Journal Article Cyclotides associate with leaf vasculature and are the products of a novel precursor in Petunia (Solanaceae)Poth, Aaron G., Mylne, Joshua S., Grassl, Julia, Lyons, Russell E., Millar, A. Harvey, Colgrave, Michelle L. and Craik, David J. (2012). Cyclotides associate with leaf vasculature and are the products of a novel precursor in Petunia (Solanaceae). Journal of Biological Chemistry, 287 (32), 27033-27046. doi: 10.1074/jbc.M112.370841 |
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2011 Journal Article The chemistry of cyclotidesCraik, David J. and Conibear, Anne C. (2011). The chemistry of cyclotides. Journal of Organic Chemistry, 76 (12), 4805-4817. doi: 10.1021/jo200520v |
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2011 Journal Article Albumins and their processing machinery are hijacked for cyclic peptides in sunflowerMylne, Joshua S., Colgrave, Michelle L., Daly, Norelle L., Chanson, Aurelie H., Elliott, Alysha G., McCallum, Emily J., Jones, Alun and Craik, David J. (2011). Albumins and their processing machinery are hijacked for cyclic peptides in sunflower. Nature Chemical Biology, 7 (5), 257-259. doi: 10.1038/nchembio.542 |
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2011 Journal Article Discovery of cyclotides in the Fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteinsPoth, Aaron G., Colgrave, Michelle L., Philip, Reynold, Kerenga, Bomai, Daly, Norelle L., Anderson, Marilyn A. and Craik, David J. (2011). Discovery of cyclotides in the Fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins. ACS Chemical Biology, 6 (4), 345-355. doi: 10.1021/cb100388j |
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2009 Journal Article Circling the enemy: cyclic proteins in plant defenceCraik, David J. (2009). Circling the enemy: cyclic proteins in plant defence. Trends in Plant Science, 14 (6), 328-335. doi: 10.1016/j.tplants.2009.03.003 |
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2009 Journal Article Conotoxins: natural product drug leadsHalai, Reena and Craik, David J. (2009). Conotoxins: natural product drug leads. Natural Product Reports, 26 (4), 526-536. doi: 10.1039/b819311h |
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2008 Journal Article Distribution and evolution of circular miniproteins in flowering plantsGruber, Christian W., Elliott, Alysha G., Ireland, David C., Delprete, Piero G., Dessein, Steven, Goransson, Ulf, Trabi, Manuela, Wang, Conan K., Kinghorn, Andrew B., Robbrecht, Elmar and Craik, David J. (2008). Distribution and evolution of circular miniproteins in flowering plants. The Plant Cell, 20 (9), 2471-2483. doi: 10.1105/tpc.108.062331 |
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2006 Journal Article Chemistry - Seamless proteins tie up their loose endsCraik, D. J. (2006). Chemistry - Seamless proteins tie up their loose ends. Science, 311 (5767), 1563-1564. doi: 10.1126/science.1125248 |
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2025 Journal Article Cyclization of the Analgesic α‐Conotoxin Vc1.1 With a Non‐Natural Linker: Effects on Structure, Stability, and BioactivityZhang, Yuhui, Tae, Han Shen, Adams, David J., Durek, Thomas and Craik, David J. (2025). Cyclization of the Analgesic α‐Conotoxin Vc1.1 With a Non‐Natural Linker: Effects on Structure, Stability, and Bioactivity. Journal of Peptide Science, 31 (6) e70017. doi: 10.1002/psc.70017 |
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2025 Journal Article An orthogonal protection strategy for the synthesis of conotoxins containing three disulfide bondsZhang, Hengyu, Chan, Lai Yue, Zhang, Huanhuan, Jiang, Tao, Craik, David J., Cai, Wenqing and Yu, Rilei (2025). An orthogonal protection strategy for the synthesis of conotoxins containing three disulfide bonds. Marine Drugs, 23 (4) 168, 1-11. doi: 10.3390/md23040168 |
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2025 Journal Article Anticoagulation during Extracorporeal Membrane Oxygenation (ECMO): A Selective Inhibitor of Activated Factor XII Compared to Heparin in an <i>Ex Vivo</i> ModelGandini, Lucia, de Veer, Simon J., Chan, Chris H. H., Passmore, Margaret R., Liu, Keibun, Lundon, Brooke, Rachakonda, Reema, White, Nicole, Rhodes, Madeleine, Shanahan, Emma, Yap, Kuok, See Hoe, Louise E., Semenzin, Clayton, Li Bassi, Gianluigi, Fraser, John F., Craik, David J. and Suen, Jacky Y. (2025). Anticoagulation during Extracorporeal Membrane Oxygenation (ECMO): A Selective Inhibitor of Activated Factor XII Compared to Heparin in an Ex Vivo Model. ACS Pharmacology & Translational Science, 8 (5), 1260-1269. doi: 10.1021/acsptsci.4c00352 |
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2025 Journal Article Selective inhibition of Rat α7 nicotinic acetylcholine receptors by LvID, a newly characterized α4/7-conotoxin from Conus lividusGuo, Man, Zhu, Xiaopeng, Ma, Tao, Xu, Chenxing, Zhangsun, Dongting, Yu, Jinpeng, Kaas, Quentin, Harvey, Peta J., McIntosh, J. Michael, Craik, David J. and Luo, Sulan (2025). Selective inhibition of Rat α7 nicotinic acetylcholine receptors by LvID, a newly characterized α4/7-conotoxin from Conus lividus. Journal of Medicinal Chemistry, 68 (8), 8163-8173. doi: 10.1021/acs.jmedchem.4c02810 |
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2025 Journal Article Cell-penetrating cyclic and disulfide-rich peptides are privileged molecular scaffolds for intracellular targetingTroeira Henriques, Sónia, Lawrence, Nicole, Kan, Meng-Wei, Malins, Lara R. and Craik, David J. (2025). Cell-penetrating cyclic and disulfide-rich peptides are privileged molecular scaffolds for intracellular targeting. Biochemistry, 64 (7), 1437-1449. doi: 10.1021/acs.biochem.4c00845 |
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2025 Journal Article Recombinant production of the cyclotide kalata B1 by conditional split inteinsCraik, David J., Yayci, Abdulkadir, Huang, Yen-Hua and Harvey, Peta J. (2025). Recombinant production of the cyclotide kalata B1 by conditional split inteins. ChemBioChem, 26 (4) e202400591. doi: 10.1002/cbic.202400591 |
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2025 Journal Article The future of utilising semiochemical pest control methods to manage the destructive crown-of-thorns starfish outbreaks on coral reefsHarris, Richard J., Barnard, d'Artagnan L., Paxton, Gillian, Lockie, Stewart, Craik, David J., Cummins, Scott F., Wang, Conan K. and Motti, Cherie A. (2025). The future of utilising semiochemical pest control methods to manage the destructive crown-of-thorns starfish outbreaks on coral reefs. Biological Conservation, 302 110984, 110984-302. doi: 10.1016/j.biocon.2025.110984 |
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2025 Journal Article Exploring the utility of cell-penetrating peptides as vehicles for the delivery of distinct antimalarial drug cargoesGare, Caitlin L., Palombi, Isabella R., White, Andrew M., Chavchich, Marina, Edstein, Michael D., Lock, Aaron, Avery, Vicky M., Craik, David J., McMorran, Brendan J., Lawrence, Nicole and Malins, Lara Rebecca (2025). Exploring the utility of cell-penetrating peptides as vehicles for the delivery of distinct antimalarial drug cargoes. ChemMedChem, 20 (2) e202400637. doi: 10.1002/cmdc.202400637 |
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2025 Journal Article Analogs of cyclic peptide mortiamide‐d from marine fungi have improved membrane permeability and kill drug‐resistant melanoma cellsBergeron, Catherine, Bérubé, Christopher, Lamb, Henry, Koda, Yasuko, Craik, David J., Henriques, Sónia Troeira, Voyer, Normand and Lawrence, Nicole (2025). Analogs of cyclic peptide mortiamide‐d from marine fungi have improved membrane permeability and kill drug‐resistant melanoma cells. Peptide Science, 117 (1) e24380. doi: 10.1002/pep2.24380 |
