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2014 Journal Article Molecular grafting onto a stable framework yields novel cyclic peptides for the treatment of multiple sclerosisWang, Conan K., Gruber, Christian W., Cemazar, Masa, Siatskas, Christopher, Tagore, Prascilla, Payne, Natalie, Sun, Guizhi, Wang, Shunhe, Bernard, Claude C. and Craik, David J. (2014). Molecular grafting onto a stable framework yields novel cyclic peptides for the treatment of multiple sclerosis. ACS Chemical Biology, 9 (1), 156-163. doi: 10.1021/cb400548s |
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2013 Journal Article The Future of Peptide-based DrugsCraik, David J., Fairlie, David P., Liras, Spiros and Price, David (2013). The Future of Peptide-based Drugs. Chemical Biology and Drug Design, 81 (1), 136-147. doi: 10.1111/cbdd.12055 |
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2012 Journal Article Protein folding: Turbo-charged crosslinkingCraik, David J. (2012). Protein folding: Turbo-charged crosslinking. Nature Chemistry, 4 (8), 600-602. doi: 10.1038/nchem.1417 |
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2012 Journal Article Cyclotides associate with leaf vasculature and are the products of a novel precursor in Petunia (Solanaceae)Poth, Aaron G., Mylne, Joshua S., Grassl, Julia, Lyons, Russell E., Millar, A. Harvey, Colgrave, Michelle L. and Craik, David J. (2012). Cyclotides associate with leaf vasculature and are the products of a novel precursor in Petunia (Solanaceae). Journal of Biological Chemistry, 287 (32), 27033-27046. doi: 10.1074/jbc.M112.370841 |
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2011 Journal Article The chemistry of cyclotidesCraik, David J. and Conibear, Anne C. (2011). The chemistry of cyclotides. Journal of Organic Chemistry, 76 (12), 4805-4817. doi: 10.1021/jo200520v |
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2011 Journal Article Albumins and their processing machinery are hijacked for cyclic peptides in sunflowerMylne, Joshua S., Colgrave, Michelle L., Daly, Norelle L., Chanson, Aurelie H., Elliott, Alysha G., McCallum, Emily J., Jones, Alun and Craik, David J. (2011). Albumins and their processing machinery are hijacked for cyclic peptides in sunflower. Nature Chemical Biology, 7 (5), 257-259. doi: 10.1038/nchembio.542 |
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2011 Journal Article Discovery of cyclotides in the Fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteinsPoth, Aaron G., Colgrave, Michelle L., Philip, Reynold, Kerenga, Bomai, Daly, Norelle L., Anderson, Marilyn A. and Craik, David J. (2011). Discovery of cyclotides in the Fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins. ACS Chemical Biology, 6 (4), 345-355. doi: 10.1021/cb100388j |
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2009 Journal Article Circling the enemy: cyclic proteins in plant defenceCraik, David J. (2009). Circling the enemy: cyclic proteins in plant defence. Trends in Plant Science, 14 (6), 328-335. doi: 10.1016/j.tplants.2009.03.003 |
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2009 Journal Article Conotoxins: natural product drug leadsHalai, Reena and Craik, David J. (2009). Conotoxins: natural product drug leads. Natural Product Reports, 26 (4), 526-536. doi: 10.1039/b819311h |
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2008 Journal Article Distribution and evolution of circular miniproteins in flowering plantsGruber, Christian W., Elliott, Alysha G., Ireland, David C., Delprete, Piero G., Dessein, Steven, Goransson, Ulf, Trabi, Manuela, Wang, Conan K., Kinghorn, Andrew B., Robbrecht, Elmar and Craik, David J. (2008). Distribution and evolution of circular miniproteins in flowering plants. The Plant Cell, 20 (9), 2471-2483. doi: 10.1105/tpc.108.062331 |
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2006 Journal Article Chemistry - Seamless proteins tie up their loose endsCraik, D. J. (2006). Chemistry - Seamless proteins tie up their loose ends. Science, 311 (5767), 1563-1564. doi: 10.1126/science.1125248 |
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2025 Journal Article Discovery of insecticidal cyclotides from the African plants Allexis batangae and Allexis obanensisKhatibi, Negin, Eteme, Olivier Ndogo, Wang, Conan K., Gilding, Edward K., Zondegoumba, Ernestine Nkwengoua, Colgrave, Michelle L., Huang, Yen-Hua and Craik, David J. (2025). Discovery of insecticidal cyclotides from the African plants Allexis batangae and Allexis obanensis. Industrial Crops and Products, 237 122073, 1-9. doi: 10.1016/j.indcrop.2025.122073 |
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2025 Journal Article Combining bioactive cell-penetrating peptides and vemurafenib to produce peptide-drug conjugates with activity against drug-resistant melanoma cellsPalombi, Isabella R., White, Andrew M., Koda, Yasuko, Craik, David J., Troeira Henriques, Sónia, Lawrence, Nicole and Malins, Lara R. (2025). Combining bioactive cell-penetrating peptides and vemurafenib to produce peptide-drug conjugates with activity against drug-resistant melanoma cells. Journal of Medicinal Chemistry acs.jmedchem.5c02367. doi: 10.1021/acs.jmedchem.5c02367 |
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2025 Journal Article Design of Bicyclic peptide tandems mimicking the homodimeric GDF15 protein to inhibit GDF15–GFRaL–RET complex cell signalingNoisier, Anaïs F. M., Sandmark, Jenny, Edfeldt, Fredrik, Backmark, Anna, Broddefalk, Johan, Wandzik, Joanna, Jurva, Ulrik, Ek, Margareta, Johansson, Carina A., Barlind, Louise, Gunnarsson, Jenny, Bigalke, Janna M., Xue, Yafeng, Frolov, Andrey I., Kankkonen, Cecilia, Roth, Robert G., Fritsch, Maria, Watcham, Sophie, van Rietschoten, Katerine, Mudd, Gemma E., Harrison, Helen, Chen, Liuhong, Skynner, Michael J., Craik, David J., Chankeshwara, Sunay V. and Lemurell, Malin (2025). Design of Bicyclic peptide tandems mimicking the homodimeric GDF15 protein to inhibit GDF15–GFRaL–RET complex cell signaling. Journal of Medicinal Chemistry, 68 (20), 21441-21457. doi: 10.1021/acs.jmedchem.5c01378 |
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2025 Journal Article Where have you been? Backtracking microplastic to its source using the biomolecular composition of the ecocoronaDawson, Amanda L., Bose, Utpal, Escobar-Correas, Sophia, Yap, Kuok, Craik, David J. and Pegg, Cassandra L. (2025). Where have you been? Backtracking microplastic to its source using the biomolecular composition of the ecocorona. Environmental Science and Technology, 59 (41), 22227-22238. doi: 10.1021/acs.est.5c09277 |
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2025 Journal Article Nickel-catalyzed cascade C-H alkynylation/hydroamination of free benzylamines for the synthesis of substituted 1H-isoindoles using a transient directing group strategyCai, Xinghao, Lu, Wei, Ma, Chen, Kang, Ying, Ren, Yuqiang, Meng, Xue, Craik, David J., Fan, Shiming, Chan, Lai Yue and Liu, Shouxin (2025). Nickel-catalyzed cascade C-H alkynylation/hydroamination of free benzylamines for the synthesis of substituted 1H-isoindoles using a transient directing group strategy. Chinese Journal of Chemistry cjoc.70222. doi: 10.1002/cjoc.70222 |
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2025 Journal Article Mixed-chirality prohibitin peptide: D-(RLARLAR)2 enhances stability and in vivo effects on obesityChan, Lai Yue, Weger, Benjamin D., Weger, Meltem, Du, Junqiao, Lawrence, Nicole, Cardoso, Marlon H., de Rezende, Samilla B., Muller, Jéssica A.I., Yap, Kuok, Tse, Brian W−C, Sokolowski, Kamil A., Sullivan, Robert K.P., Gunter, Jennifer, Franco, Octávio L., Gachon, Frédéric and Craik, David J. (2025). Mixed-chirality prohibitin peptide: D-(RLARLAR)2 enhances stability and in vivo effects on obesity. Journal of the American Chemical Society, 147 (28), 24628-24642. doi: 10.1021/jacs.5c05536 |
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2025 Journal Article Asparaginyl Ligases with Engineered Substrate Specificity for Controlled, Sequential Transpeptidation ReactionsZhou, Yan, de Veer, Simon J., Tyler, Tristan J., Chen, Yufei, Durek, Thomas, Craik, David J. and Rehm, Fabian B. H. (2025). Asparaginyl Ligases with Engineered Substrate Specificity for Controlled, Sequential Transpeptidation Reactions. Journal of the American Chemical Society, 147 (25), 21824-21831. doi: 10.1021/jacs.5c04693 |
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2025 Journal Article High-throughput enrichment of functional disulfide-rich peptides by droplet microfluidicsXie, Jing, Yap, Kuok, de Veer, Simon J., Edwardraja, Selvakumar, Durek, Thomas, Trau, Matt, Craik, David J. and Wang, Conan K. (2025). High-throughput enrichment of functional disulfide-rich peptides by droplet microfluidics. Lab on a Chip, 25 (14), 3525-3536. doi: 10.1039/d5lc00261c |
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2025 Journal Article Exploring use of a protein cage system for producing bioactive peptides in Escherichia coliHarding, Maxim D., Jackson, Mark A., Gilding, Edward K., Yap, Kuok, Craik, David J., Sainsbury, Frank and Lawrence, Nicole (2025). Exploring use of a protein cage system for producing bioactive peptides in Escherichia coli. Microbial Biotechnology, 18 (6) e70158, e70158. doi: 10.1111/1751-7915.70158 |
