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2014 Journal Article Molecular grafting onto a stable framework yields novel cyclic peptides for the treatment of multiple sclerosisWang, Conan K., Gruber, Christian W., Cemazar, Masa, Siatskas, Christopher, Tagore, Prascilla, Payne, Natalie, Sun, Guizhi, Wang, Shunhe, Bernard, Claude C. and Craik, David J. (2014). Molecular grafting onto a stable framework yields novel cyclic peptides for the treatment of multiple sclerosis. ACS Chemical Biology, 9 (1), 156-163. doi: 10.1021/cb400548s |
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2013 Journal Article The Future of Peptide-based DrugsCraik, David J., Fairlie, David P., Liras, Spiros and Price, David (2013). The Future of Peptide-based Drugs. Chemical Biology and Drug Design, 81 (1), 136-147. doi: 10.1111/cbdd.12055 |
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2012 Journal Article Protein folding: Turbo-charged crosslinkingCraik, David J. (2012). Protein folding: Turbo-charged crosslinking. Nature Chemistry, 4 (8), 600-602. doi: 10.1038/nchem.1417 |
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2012 Journal Article Cyclotides associate with leaf vasculature and are the products of a novel precursor in Petunia (Solanaceae)Poth, Aaron G., Mylne, Joshua S., Grassl, Julia, Lyons, Russell E., Millar, A. Harvey, Colgrave, Michelle L. and Craik, David J. (2012). Cyclotides associate with leaf vasculature and are the products of a novel precursor in Petunia (Solanaceae). Journal of Biological Chemistry, 287 (32), 27033-27046. doi: 10.1074/jbc.M112.370841 |
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2011 Journal Article The chemistry of cyclotidesCraik, David J. and Conibear, Anne C. (2011). The chemistry of cyclotides. Journal of Organic Chemistry, 76 (12), 4805-4817. doi: 10.1021/jo200520v |
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2011 Journal Article Albumins and their processing machinery are hijacked for cyclic peptides in sunflowerMylne, Joshua S., Colgrave, Michelle L., Daly, Norelle L., Chanson, Aurelie H., Elliott, Alysha G., McCallum, Emily J., Jones, Alun and Craik, David J. (2011). Albumins and their processing machinery are hijacked for cyclic peptides in sunflower. Nature Chemical Biology, 7 (5), 257-259. doi: 10.1038/nchembio.542 |
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2011 Journal Article Discovery of cyclotides in the Fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteinsPoth, Aaron G., Colgrave, Michelle L., Philip, Reynold, Kerenga, Bomai, Daly, Norelle L., Anderson, Marilyn A. and Craik, David J. (2011). Discovery of cyclotides in the Fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins. ACS Chemical Biology, 6 (4), 345-355. doi: 10.1021/cb100388j |
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2009 Journal Article Circling the enemy: cyclic proteins in plant defenceCraik, David J. (2009). Circling the enemy: cyclic proteins in plant defence. Trends in Plant Science, 14 (6), 328-335. doi: 10.1016/j.tplants.2009.03.003 |
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2009 Journal Article Conotoxins: natural product drug leadsHalai, Reena and Craik, David J. (2009). Conotoxins: natural product drug leads. Natural Product Reports, 26 (4), 526-536. doi: 10.1039/b819311h |
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2008 Journal Article Distribution and evolution of circular miniproteins in flowering plantsGruber, Christian W., Elliott, Alysha G., Ireland, David C., Delprete, Piero G., Dessein, Steven, Goransson, Ulf, Trabi, Manuela, Wang, Conan K., Kinghorn, Andrew B., Robbrecht, Elmar and Craik, David J. (2008). Distribution and evolution of circular miniproteins in flowering plants. The Plant Cell, 20 (9), 2471-2483. doi: 10.1105/tpc.108.062331 |
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2006 Journal Article Chemistry - Seamless proteins tie up their loose endsCraik, D. J. (2006). Chemistry - Seamless proteins tie up their loose ends. Science, 311 (5767), 1563-1564. doi: 10.1126/science.1125248 |
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2026 Journal Article Minidomains from evolution for scaffold engineeringDevnath, Hiron Saraj, Xie, Jing, Craik, David J. and Wang, Conan K. (2026). Minidomains from evolution for scaffold engineering. Biotechnology Advances, 90 108904, 1-19. doi: 10.1016/j.biotechadv.2026.108904 |
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2026 Journal Article Bacteriophage P22 virus-like particles as nanoscale protein scaffolds for plant synthetic biologyHarding, Maxim D., Jackson, Mark A., Gilding, Edward K., Craik, David J., Sainsbury, Frank and Lawrence, Nicole (2026). Bacteriophage P22 virus-like particles as nanoscale protein scaffolds for plant synthetic biology. doi: 10.64898/2026.05.14.725278 |
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2026 Journal Article Computer-Aided Design of <i>Plasmodium chabaudi</i> -Derived Peptides with Dual Antibiofilm and Anti-inflammatory ActivitiesQuigua Orozco, Raquel M., Santos, Alexandre D. O., Rossetto, Joelma P., Madalozzo, Elisângela S., Luchi, Lívia V., Rezende, Samilla B., Chan, Lai Yue, Buccini, Danieli F., Macedo, Maria L. R., Mehta, Angela, Craik, David J., Franco, Octávio L. and Cardoso, Marlon H. (2026). Computer-Aided Design of Plasmodium chabaudi -Derived Peptides with Dual Antibiofilm and Anti-inflammatory Activities. ACS Medicinal Chemistry Letters, 17 (5) acsmedchemlett.6c00007, 1057-1066. doi: 10.1021/acsmedchemlett.6c00007 |
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2026 Journal Article Site-specific protein and peptide modification by redeploying an asparaginyl ligase for noncanonical reactionsde Veer, Simon J., Zhou, Yan, Rehm, Fabian B. H., Durek, Thomas and Craik, David J. (2026). Site-specific protein and peptide modification by redeploying an asparaginyl ligase for noncanonical reactions. Nature Protocols. doi: 10.1038/s41596-026-01348-8 |
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2026 Journal Article Biotechnological approaches for producing therapeutic peptides in plantsThanthrige, Nipuni, Lawrence, Nicole and Craik, David J. (2026). Biotechnological approaches for producing therapeutic peptides in plants. npj Science of Plants, 2 (1) 12. doi: 10.1038/s44383-026-00021-z |
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2026 Journal Article Enzyme‐assisted synthesis and in vitro characterization of bifunctional PCSK9 inhibitorsZhang, Yuhui, Wang, Li, Corcilius, Leo, Reji, Amal K., Payne, Richard J., Hong, Bin, Durek, Thomas, Wang, Conan K. and Craik, David J. (2026). Enzyme‐assisted synthesis and in vitro characterization of bifunctional PCSK9 inhibitors. ChemBioChem, 27 (7) e202500972. doi: 10.1002/cbic.202500972 |
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2026 Journal Article Cofilin hyperphosphorylation triggers TDP-43 pathology in sporadic amyotrophic lateral sclerosisJagaraj, Cyril Jones, Saravanabavan, Sayanthooran, Parakh, Sonam, Jayakumar, Mrithulabashini, Kashani, Sara Assar, Shadfar, Sina, Mehta, Prachi, Gautam, Shashi, Farzana, Fabiha, Suchowerska, Alexandra K, Yap, Kuok, Vidal, Marta, Ragagnin, Audrey M G, Jamali, Md Shafi, Yang, Shu, Fath, Thomas, Craik, David and Atkin, Julie D (2026). Cofilin hyperphosphorylation triggers TDP-43 pathology in sporadic amyotrophic lateral sclerosis. Brain awag096. doi: 10.1093/brain/awag096 |
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2026 Journal Article α-Conotoxin LvID, an antagonist of α7 nicotinic acetylcholine receptor, mitigates Alzheimer-associated phenotypes by inhibiting Aβ deposition and reactive astrogliosisYue, Song, Xing, Haonan, Du, Xiaoxue, Wang, Yufei, Qin, Runtian, He, Jinsheng, Yu, Jinpeng, Zhangsun, Dongting, Craik, David J., Mcintosh, J. Michael, Wu, Yili, Zhu, Xiaopeng and Luo, Sulan (2026). α-Conotoxin LvID, an antagonist of α7 nicotinic acetylcholine receptor, mitigates Alzheimer-associated phenotypes by inhibiting Aβ deposition and reactive astrogliosis. International Journal of Biological Macromolecules, 349 150933, 1-15. doi: 10.1016/j.ijbiomac.2026.150933 |
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2026 Journal Article Rational Design of Plant-Derived Protein Ligases with Altered Substrate SpecificityZhou, Yan, de Veer, Simon J., Tyler, Tristan J., Durek, Thomas, Rehm, Fabian B. H. and Craik, David J. (2026). Rational Design of Plant-Derived Protein Ligases with Altered Substrate Specificity. Biochemistry, 65 (5) acs.biochem.5c00808, 571-578. doi: 10.1021/acs.biochem.5c00808 |
