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2023 Journal Article Development of a selective peptide κ-opioid receptor antagonist by late-stage functionalization with cysteine staplesMuratspahić, Edin, White, Andrew M., Ciotu, Cosmin I., Hochrainer, Nadine, Tomašević, Nataša, Koehbach, Johannes, Lewis, Richard J., Spetea, Mariana, Fischer, Michael J. M., Craik, David J. and Gruber, Christian W. (2023). Development of a selective peptide κ-opioid receptor antagonist by late-stage functionalization with cysteine staples. Journal of Medicinal Chemistry, 66 (17), 11843-11854. doi: 10.1021/acs.jmedchem.3c00426 |
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2023 Journal Article Exploring the therapeutic potential of an antinociceptive and anti-inflammatory peptide from wasp venomGalante, Priscilla, Campos, Gabriel A. A., Moser, Jacqueline C. G., Martins, Danubia B., Dos Santos Cabrera, Marcia P., Rangel, Marisa, Coelho, Luiza C., Simon, Karina S., Amado, Veronica M., de A. I. Muller, Jessica, Koehbach, Johannes, Lohman, Rink-Jan, Cabot, Peter J., Vetter, Irina, Craik, David J., Toffoli-Kadri, Monica C., Monge-Fuentes, Victoria, Goulart, Jair T., Schwartz, Elisabeth F., Silva, Luciano P., Bocca, Anamelia L. and Mortari, Márcia R (2023). Exploring the therapeutic potential of an antinociceptive and anti-inflammatory peptide from wasp venom. Scientific Reports, 13 (1) 12491, 1-15. doi: 10.1038/s41598-023-38828-w |
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2023 Journal Article Structure–activity relationships of alanine scan mutants αO-conotoxins GeXIVA[1,2] and GeXIVA[1,4]Xu, Pan, Zhang, Panpan, Zhu, Xiaopeng, Wu, Yong, Harvey, Peta J., Kaas, Quentin, Zhangsun, Dongting, Craik, David J. and Luo, Sulan (2023). Structure–activity relationships of alanine scan mutants αO-conotoxins GeXIVA[1,2] and GeXIVA[1,4]. Journal of Medicinal Chemistry, 66 (14), 10092-10107. doi: 10.1021/acs.jmedchem.3c01023 |
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2023 Journal Article Native and engineered cyclic disulfide-rich peptides as drug leadsTyler, Tristan J., Durek, Thomas and Craik, David J. (2023). Native and engineered cyclic disulfide-rich peptides as drug leads. Molecules, 28 (7) 3189, 1-22. doi: 10.3390/molecules28073189 |
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2023 Journal Article Design, synthesis and mechanism of action of novel μ-conotoxin KIIIA analogs for inhibition of the voltage-gated sodium channel Nav1.7Zhao, Zitong, Pan, Teng, Chen, Shen, Harvey, Peta J., Zhang, Jinghui, Li, Xiao, Yang, Mengke, Huang, Linhong, Wang, Shoushi, Craik, David J., Jiang, Tao and Yu, Rilei (2023). Design, synthesis and mechanism of action of novel μ-conotoxin KIIIA analogs for inhibition of the voltage-gated sodium channel Nav1.7. Journal of Biological Chemistry, 299 (4) 103068, 1-12. doi: 10.1016/j.jbc.2023.103068 |
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2023 Journal Article Unlocking the potential of the antimicrobial peptide gomesin: from discovery and structure–activity relationships to therapeutic applicationsLiu, Xiaorong, Henriques, Sónia T., Craik, David J. and Chan, Lai Yue (2023). Unlocking the potential of the antimicrobial peptide gomesin: from discovery and structure–activity relationships to therapeutic applications. International Journal of Molecular Sciences, 24 (6) 5893, 1-15. doi: 10.3390/ijms24065893 |
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2023 Journal Article Designing antimicrobial peptides using deep learning and molecular dynamic simulationsCao, Qiushi, Ge, Cheng, Wang, Xuejie, Harvey, Peta J., Zhang, Zixuan, Ma, Yuan, Wang, Xianghong, Jia, Xinying, Mobli, Mehdi, Craik, David J., Jiang, Tao, Yang, Jinbo, Wei, Zhiqiang, Wang, Yan, Chang, Shan and Yu, Rilei (2023). Designing antimicrobial peptides using deep learning and molecular dynamic simulations. Briefings in Bioinformatics, 24 (2) bbad058, 1-13. doi: 10.1093/bib/bbad058 |
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2023 Journal Article Bibliometric review of the literature on cone snail peptide toxins from 2000 to 2022Nguyen, Linh T. T., Craik, David J. and Kaas, Quentin (2023). Bibliometric review of the literature on cone snail peptide toxins from 2000 to 2022. Marine Drugs, 21 (3) 154, 1-15. doi: 10.3390/md21030154 |
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2023 Journal Article Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiationChen, Zhian, Cui, Yanfang, Yao, Yin, Liu, Bo, Yunis, Joseph, Gao, Xin, Wang, Naiqi, Cañete, Pablo F., Tuong, Zewen Kelvin, Sun, Hongjian, Wang, Hao, Yang, Siling, Wang, Runli, Leong, Yew Ann, Simon Davis, David, Qin, Jiahuan, Liang, Kaili, Deng, Jun, Wang, Conan K., Huang, Yen-Hua, Roco, Jonathan A., Nettelfield, Sam, Zhu, Huaming, Xu, Huajun, Yu, Zhijia, Craik, David, Liu, Zheng, Qi, Hai, Parish, Christopher and Yu, Di (2023). Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation. Science immunology, 8 (80) eadd1728, 1-17. doi: 10.1126/sciimmunol.add1728 |
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2023 Journal Article Discovery, characterization, and engineering of LvIC, an α4/4-conotoxin that selectively blocks rat α6/α3β4 nicotinic acetylcholine receptorsZhu, Xiaopeng, Wang, Shuai, Kaas, Quentin, Yu, Jinpeng, Wu, Yong, Harvey, Peta J., Zhangsun, Dongting, Craik, David J. and Luo, Sulan (2023). Discovery, characterization, and engineering of LvIC, an α4/4-conotoxin that selectively blocks rat α6/α3β4 nicotinic acetylcholine receptors. Journal of Medicinal Chemistry, 66 (3), 2020-2031. doi: 10.1021/acs.jmedchem.2c01786 |
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2023 Other Outputs Ct_HiC3 assembly and analysis dataGilding, Edward and Craik, David (2023). Ct_HiC3 assembly and analysis data. The University of Queensland. (Dataset) doi: 10.48610/757738c |
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2022 Journal Article Sex-specific expression of pheromones and other signals in gravid starfishJönsson, Mathias, Morin, Marie, Wang, Conan K., Craik, David J., Degnan, Sandie M. and Degnan, Bernard M. (2022). Sex-specific expression of pheromones and other signals in gravid starfish. BMC Biology, 20 (1) 288, 1-18. doi: 10.1186/s12915-022-01491-0 |
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2022 Journal Article Cancer-related micropeptides encoded by ncRNAs: Promising drug targets and prognostic biomarkersSetrerrahmane, Sarra, Li, Mengwei, Zoghbi, Abdelmoumin, Lv, Xue, Zhang, Sen, Zhao, Wenjing, Lu, Jingjing, Craik, David J. and Xu, Hanmei (2022). Cancer-related micropeptides encoded by ncRNAs: Promising drug targets and prognostic biomarkers. Cancer Letters, 547 215723, 1-12. doi: 10.1016/j.canlet.2022.215723 |
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2022 Journal Article Structural analysis of the complex of human transthyretin with 3′,5′-dichlorophenylanthranilic acid at 1.5 Å resolutionCody, Vivian, Truong, Jia Q., Holdsworth, Bruce A., Holien, Jessica K., Richardson, Samantha J., Chalmers, David K. and Craik, David J. (2022). Structural analysis of the complex of human transthyretin with 3′,5′-dichlorophenylanthranilic acid at 1.5 Å resolution. Molecules, 27 (21) 7206, 1-11. doi: 10.3390/molecules27217206 |
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2022 Journal Article A designed cyclic analogue of gomesin has potent activity against Staphylococcus aureus biofilmsDias, Susana A., Pinto, Sandra N., Silva-Herdade, Ana S., Cheneval, Olivier, Craik, David J., Coutinho, Ana, Castanho, Miguel A. R. B., Henriques, Sónia T. and Veiga, Ana Salomé (2022). A designed cyclic analogue of gomesin has potent activity against Staphylococcus aureus biofilms. Journal of Antimicrobial Chemotherapy, 77 (12), 3256-3264. doi: 10.1093/jac/dkac309 |
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2022 Journal Article µ-Conotoxins targeting the human voltage-gated sodium channel subtype NaV1.7McMahon, Kirsten L., Tran, Hue N. T., Deuis, Jennifer R., Craik, David J., Vetter, Irina and Schroeder, Christina I. (2022). µ-Conotoxins targeting the human voltage-gated sodium channel subtype NaV1.7. Toxins, 14 (9) 600, 1-16. doi: 10.3390/toxins14090600 |
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2022 Conference Publication Activating the p53 pathway with peptide conjugates: synthesis, structure, activity and cellular uptakePhilippe, Gregoire, Huang, Yen-Hua, Mittermeier, Anna, Brown, Christopher, Wang, Conan, Kaas, Quentin, Lawrence, Nicole, Condon, Nicholas, Lane, David, Loewer, Alexander, Craik, David and Henriques, Sonia (2022). Activating the p53 pathway with peptide conjugates: synthesis, structure, activity and cellular uptake. 36th European Peptide Symposium 12th International Peptide Symposium, Barcelona, Spain, 28 August - 2 September 2022. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.3445 |
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2022 Journal Article Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica feroxXie, Jing, Robinson, Samuel D., Gilding, Edward K., Jami, Sina, Deuis, Jennifer R., Rehm, Fabian B.H., Yap, Kuok, Ragnarsson, Lotten, Chan, Lai Yue, Hamilton, Brett R., Harvey, Peta J., Craik, David J., Vetter, Irina and Durek, Thomas (2022). Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica ferox. Journal of Biological Chemistry, 298 (8) 102218, 1-12. doi: 10.1016/j.jbc.2022.102218 |
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2022 Journal Article Mutagenesis of cyclotide Cter 27 exemplifies a robust folding strategy for bracelet cyclotidesDang, Tien T., Harvey, Peta J., Chan, Lai Yue, Huang, Yen-Hua, Kaas, Quentin and Craik, David J. (2022). Mutagenesis of cyclotide Cter 27 exemplifies a robust folding strategy for bracelet cyclotides. Peptide Science, 114 (6) e24284. doi: 10.1002/pep2.24284 |
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2022 Journal Article Antinociceptive peptides from venomous arthropodsMuller, Jessica A. I., Chan, Lai Y., Toffoli-Kadri, Monica C., Mortari, Marcia R., Craik, David J. and Koehbach, Johannes (2022). Antinociceptive peptides from venomous arthropods. Toxin Reviews, 42 (1), 1-20. doi: 10.1080/15569543.2022.2065510 |
