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2024 Journal Article Isolation and characterization of insecticidal cyclotides from Viola communisKhatibi, Negin, Huang, Yen-Hua, Wang, Conan K., Durek, Thomas, Gilding, Edward K. and Craik, David J. (2024). Isolation and characterization of insecticidal cyclotides from Viola communis. Journal of Natural Products, 88 (1), 24-35. doi: 10.1021/acs.jnatprod.4c00168 |
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2024 Journal Article Seasonal tissue-specific gene expression in wild crown-of-thorns starfish reveals reproductive and stress-related transcriptional systemsMorin, Marie, Jönsson, Mathias, Wang, Conan K., Craik, David J., Degnan, Sandie M. and Degnan, Bernard M. (2024). Seasonal tissue-specific gene expression in wild crown-of-thorns starfish reveals reproductive and stress-related transcriptional systems. PLOS Biology, 22 (5) e3002620, e3002620. doi: 10.1371/journal.pbio.3002620 |
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2024 Journal Article Chemical synthesis of grafted cyclotides using a “plug and play” approachKoehbach, Johannes, Muratspahić, Edin, Ahmed, Zakaria M., White, Andrew M., Tomašević, Nataša, Durek, Thomas, Clark, Richard J., Gruber, Christian W. and Craik, David J. (2024). Chemical synthesis of grafted cyclotides using a “plug and play” approach. RSC Chemical Biology, 5 (6), 567-571. doi: 10.1039/d4cb00008k |
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2024 Journal Article Proximity labelling confirms the involvement of papain-like cysteine proteases and chaperones in cyclotide biosynthesisLee, Meng-Han, Jackson, Mark A., Rehm, Fabian B. H., Barkauskas, Deborah S., Ho, Wing L., Yap, Kuok, Craik, David J. and Gilding, Edward K. (2024). Proximity labelling confirms the involvement of papain-like cysteine proteases and chaperones in cyclotide biosynthesis. Plant Molecular Biology Reporter, 42 (3), 611-623. doi: 10.1007/s11105-024-01462-5 |
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2024 Journal Article Nucleation of a key beta-turn promotes cyclotide oxidative foldingTian, Sixin, de Veer, Simon J., Durek, Thomas, Wang, Conan K. and Craik, David J. (2024). Nucleation of a key beta-turn promotes cyclotide oxidative folding. Journal of Biological Chemistry, 300 (4) 107125, 107125. doi: 10.1016/j.jbc.2024.107125 |
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2024 Journal Article Tertiary amide bond formation by an engineered asparaginyl ligasede Veer, Simon J., Zhou, Yan, Durek, Thomas, Craik, David J. and Rehm, Fabian B. H. (2024). Tertiary amide bond formation by an engineered asparaginyl ligase. Chemical Science, 15 (14) 06352, 5248-5255. doi: 10.1039/d3sc06352f |
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2024 Journal Article Molecular dynamics simulations support a preference of cyclotide kalata B1 for phosphatidylethanolamine phospholipidsRoseli, Ras Baizureen, Huang, Yen-Hua, Henriques, Sónia Troeira, Kaas, Quentin and Craik, David J. (2024). Molecular dynamics simulations support a preference of cyclotide kalata B1 for phosphatidylethanolamine phospholipids. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1866 (3) 184268, 1-13. doi: 10.1016/j.bbamem.2023.184268 |
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2024 Journal Article Scanning mutagenesis identifies residues that improve the long-term stability and insecticidal activity of cyclotide kalata B1Huang, Yen-Hua, Jiang, Zhihao, Du, Qingdan, Yap, Kuok, Bigot, Aurélien, Kaas, Quentin, Wang, Conan K. and Craik, David J. (2024). Scanning mutagenesis identifies residues that improve the long-term stability and insecticidal activity of cyclotide kalata B1. Journal of Biological Chemistry, 300 (3) 105682. doi: 10.1016/j.jbc.2024.105682 |
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2024 Journal Article Deciphering the structure and mechanism‐of‐action of computer‐designed mastoparan peptidesOshiro, Karen G. N., Freitas, Carlos D. P., Rezende, Samilla B., Orozco, Raquel M. Q., Chan, Lai Y., Lawrence, Nicole, Lião, Luciano M., Macedo, Maria L. R., Craik, David J., Cardoso, Marlon H. and Franco, Octávio L. (2024). Deciphering the structure and mechanism‐of‐action of computer‐designed mastoparan peptides. The FEBS Journal, 291 (5), 865-883. doi: 10.1111/febs.17010 |
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2024 Journal Article Sortase‐Catalyzed Protein Domain InversionZhou, Yan, Durek, Thomas, Craik, David J. and Rehm, Fabian B. H. (2024). Sortase‐Catalyzed Protein Domain Inversion. Angewandte Chemie, 136 (14). doi: 10.1002/ange.202316777 |
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2024 Journal Article Sortase‐Catalyzed Protein Domain InversionZhou, Yan, Durek, Thomas, Craik, David J. and Rehm, Fabian B. H. (2024). Sortase‐Catalyzed Protein Domain Inversion. Angewandte Chemie International Edition, 63 (14) e202316777, 1-7. doi: 10.1002/anie.202316777 |
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2024 Journal Article Computational design of α‐conotoxins to target specific nicotinic acetylcholine receptor subtypesWu, Xiaosa, Hone, Arik J., Huang, Yen-Hua, Clark, Richard J., McIntosh, J. Michael, Kaas, Quentin and Craik, David J. (2024). Computational design of α‐conotoxins to target specific nicotinic acetylcholine receptor subtypes. Chemistry – A European Journal, 30 (7) e202302909, 1-5. doi: 10.1002/chem.202302909 |
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2024 Journal Article Delivery to, and Reactivation of, the p53 Pathway in Cancer Cells Using a Grafted Cyclotide Conjugated with a Cell-Penetrating PeptidePhilippe, Grégoire Jean-Baptiste, Huang, Yen-Hua, Mittermeier, Anna, Brown, Christopher J., Kaas, Quentin, Ramlan, Siti Radhiah, Wang, Conan K., Lane, David, Loewer, Alexander, Troeira Henriques, Sónia and Craik, David J. (2024). Delivery to, and Reactivation of, the p53 Pathway in Cancer Cells Using a Grafted Cyclotide Conjugated with a Cell-Penetrating Peptide. Journal of Medicinal Chemistry, 67 (2), 1197-1208. doi: 10.1021/acs.jmedchem.3c01682 |
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2024 Journal Article The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptideBaquero, Fernando, Beis, Konstantinos, Craik, David J., Li, Yanyan, Link, A. James, Rebuffat, Sylvie, Salomón, Raúl, Severinov, Konstantin, Zirah, Séverine and Hegemann, Julian D. (2024). The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide. Natural Product Reports, 41 (3), 469-511. doi: 10.1039/d3np00046j |
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2024 Journal Article The prospect of substrate-based kinase inhibitors to improve target selectivity and overcome drug resistanceBiswas, Biswajit, Huang, Yen-Hua, Craik, David J. and Wang, Conan K. (2024). The prospect of substrate-based kinase inhibitors to improve target selectivity and overcome drug resistance. Chemical Science, 15 (33), 13130-13147. doi: 10.1039/d4sc01088d |
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2024 Book Chapter Functional divergence in plant cyclotides and their role in plant defenseKhatri, Bhavesh and Craik, David J. (2024). Functional divergence in plant cyclotides and their role in plant defense. Defense-related proteins in plants. (pp. 241-262) edited by Santosh Kumar Upadhyay. London, United Kingdom: Academic Press. doi: 10.1016/b978-0-443-13236-0.00009-9 |
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2023 Journal Article Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptorMuratspahić, Edin, Deibler, Kristine, Han, Jianming, Tomašević, Nataša, Jadhav, Kirtikumar B., Olivé-Marti, Aina-Leonor, Hochrainer, Nadine, Hellinger, Roland, Koehbach, Johannes, Fay, Jonathan F., Rahman, Mohammad Homaidur, Hegazy, Lamees, Craven, Timothy W., Varga, Balazs R., Bhardwaj, Gaurav, Appourchaux, Kevin, Majumdar, Susruta, Muttenthaler, Markus, Hosseinzadeh, Parisa, Craik, David J., Spetea, Mariana, Che, Tao, Baker, David and Gruber, Christian W. (2023). Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor. Nature Communications, 14 (1) 8064, 1-17. doi: 10.1038/s41467-023-43718-w |
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2023 Journal Article The plant defensin Ppdef1 is a novel topical treatment for onychomycosisvan der Weerden, Nicole L., Parisi, Kathy, McKenna, James A., Hayes, Brigitte M., Harvey, Peta J., Quimbar, Pedro, Wevrett, Sean R., Veneer, Prem K., McCorkelle, Owen, Vasa, Shaily, Guarino, Rosemary, Poon, Simon, Gaspar, Yolanda M., Baker, Michael J., Craik, David J., Turner, Rob B., Brown, Marc B., Bleackley, Mark R. and Anderson, Marilyn A. (2023). The plant defensin Ppdef1 is a novel topical treatment for onychomycosis. Journal of Fungi, 9 (11) 1111, 1-16. doi: 10.3390/jof9111111 |
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2023 Journal Article Discovery and optimisation of conotoxin Vc1.1 and analogues with analgesic propertiesFrøsig-Jørgensen, Majbrit, Ji, Jing, Gorman, Declan M., Kan, Meng-Wei and Craik, David J. (2023). Discovery and optimisation of conotoxin Vc1.1 and analogues with analgesic properties. Australian Journal of Chemistry, 76 (10), 1-16. doi: 10.1071/ch23155 |
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2023 Journal Article Development of melanocortin 4 receptor agonists by exploiting animal-derived macrocyclic, disulfide-rich peptide scaffoldsMuratspahić, Edin, Aslanoglou, Despoina, White, Andrew M., Draxler, Claudia, Kozisek, Xaver, Farooq, Zara, Craik, David J., McCormick, Peter J., Durek, Thomas and Gruber, Christian W. (2023). Development of melanocortin 4 receptor agonists by exploiting animal-derived macrocyclic, disulfide-rich peptide scaffolds. ACS Pharmacology and Translational Science, 6 (10), 1373-1381. doi: 10.1021/acsptsci.3c00090 |
