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2022 Journal Article Structural analysis of the complex of human transthyretin with 3′,5′-dichlorophenylanthranilic acid at 1.5 Å resolutionCody, Vivian, Truong, Jia Q., Holdsworth, Bruce A., Holien, Jessica K., Richardson, Samantha J., Chalmers, David K. and Craik, David J. (2022). Structural analysis of the complex of human transthyretin with 3′,5′-dichlorophenylanthranilic acid at 1.5 Å resolution. Molecules, 27 (21) 7206, 1-11. doi: 10.3390/molecules27217206 |
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2022 Journal Article A designed cyclic analogue of gomesin has potent activity against Staphylococcus aureus biofilmsDias, Susana A., Pinto, Sandra N., Silva-Herdade, Ana S., Cheneval, Olivier, Craik, David J., Coutinho, Ana, Castanho, Miguel A. R. B., Henriques, Sónia T. and Veiga, Ana Salomé (2022). A designed cyclic analogue of gomesin has potent activity against Staphylococcus aureus biofilms. Journal of Antimicrobial Chemotherapy, 77 (12), 3256-3264. doi: 10.1093/jac/dkac309 |
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2022 Journal Article µ-Conotoxins targeting the human voltage-gated sodium channel subtype NaV1.7McMahon, Kirsten L., Tran, Hue N. T., Deuis, Jennifer R., Craik, David J., Vetter, Irina and Schroeder, Christina I. (2022). µ-Conotoxins targeting the human voltage-gated sodium channel subtype NaV1.7. Toxins, 14 (9) 600, 1-16. doi: 10.3390/toxins14090600 |
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2022 Journal Article Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica feroxXie, Jing, Robinson, Samuel D., Gilding, Edward K., Jami, Sina, Deuis, Jennifer R., Rehm, Fabian B.H., Yap, Kuok, Ragnarsson, Lotten, Chan, Lai Yue, Hamilton, Brett R., Harvey, Peta J., Craik, David J., Vetter, Irina and Durek, Thomas (2022). Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica ferox. Journal of Biological Chemistry, 298 (8) 102218, 1-12. doi: 10.1016/j.jbc.2022.102218 |
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2022 Conference Publication Activating the p53 pathway with peptide conjugates: synthesis, structure, activity and cellular uptakePhilippe, Gregoire, Huang, Yen-Hua, Mittermeier, Anna, Brown, Christopher, Wang, Conan, Kaas, Quentin, Lawrence, Nicole, Condon, Nicholas, Lane, David, Loewer, Alexander, Craik, David and Henriques, Sonia (2022). Activating the p53 pathway with peptide conjugates: synthesis, structure, activity and cellular uptake. 36th European Peptide Symposium 12th International Peptide Symposium, Barcelona, Spain, 28 August - 2 September 2022. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.3445 |
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2022 Conference Publication Plant-based production of therapeutic peptidesCraik, David (2022). Plant-based production of therapeutic peptides. HOBOKEN: WILEY. |
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2022 Journal Article Mutagenesis of cyclotide Cter 27 exemplifies a robust folding strategy for bracelet cyclotidesDang, Tien T., Harvey, Peta J., Chan, Lai Yue, Huang, Yen-Hua, Kaas, Quentin and Craik, David J. (2022). Mutagenesis of cyclotide Cter 27 exemplifies a robust folding strategy for bracelet cyclotides. Peptide Science, 114 (6) e24284. doi: 10.1002/pep2.24284 |
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2022 Journal Article Antinociceptive peptides from venomous arthropodsMuller, Jessica A. I., Chan, Lai Y., Toffoli-Kadri, Monica C., Mortari, Marcia R., Craik, David J. and Koehbach, Johannes (2022). Antinociceptive peptides from venomous arthropods. Toxin Reviews, 42 (1), 1-20. doi: 10.1080/15569543.2022.2065510 |
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2022 Journal Article Cystine knot peptides with tuneable activity and mechanismLi, Choi Yi, Rehm, Fabian B. H., Yap, Kuok, Zdenek, Christina N., Harding, Maxim D., Fry, Bryan G., Durek, Thomas, Craik, David J. and Veer, Simon J. (2022). Cystine knot peptides with tuneable activity and mechanism. Angewandte Chemie, 61 (19) e202200951, e202200951. doi: 10.1002/ange.202200951 |
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2022 Journal Article Phage display-based discovery of cyclic peptides against the broad spectrum bacterial anti-virulence target CsrAJakob, Valentin, Zoller, Ben G. E., Rinkes, Julia, Wu, Yingwen, Kiefer, Alexander F., Hust, Michael, Polten, Saskia, White, Andrew M., Harvey, Peta J., Durek, Thomas, Craik, David J., Siebert, Andreas, Kazmaier, Uli and Empting, Martin (2022). Phage display-based discovery of cyclic peptides against the broad spectrum bacterial anti-virulence target CsrA. European Journal of Medicinal Chemistry, 231 114148, 114148. doi: 10.1016/j.ejmech.2022.114148 |
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2022 Journal Article ɑO-Conotoxin GeXIVA isomers modulate N-type calcium (CaV2.2) channels and inwardly-rectifying potassium (GIRK) channels via GABAB receptor activationYousuf, Arsalan, Wu, Xiaosa, Bony, Anuja R., Sadeghi, Mahsa, Huang, Yen-Hua, Craik, David J. and Adams, David J. (2022). ɑO-Conotoxin GeXIVA isomers modulate N-type calcium (CaV2.2) channels and inwardly-rectifying potassium (GIRK) channels via GABAB receptor activation. Journal of Neurochemistry, 160 (2), 154-171. doi: 10.1111/jnc.15535 |
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2022 Book Chapter Cyclotides—cyclic and disulfide-knotted polypeptidesCraik, David J., Zhang, Yuhui, Zhou, Yan, Kaas, Quentin and Kan, Meng-Wei (2022). Cyclotides—cyclic and disulfide-knotted polypeptides. Topological polymer chemistry: concepts and practices. (pp. 135-147) Singapore, Singapore: Springer Singapore. doi: 10.1007/978-981-16-6807-4_9 |
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2022 Journal Article An N-capping asparagine–lysine–proline (NKP) motif contributes to a hybrid flexible/stable multifunctional peptide scaffoldCardoso, Marlon H., Chan, Lai Y., Cândido, Elizabete S., Buccini, Danieli F., Rezende, Samilla B., Torres, Marcelo D. T., Oshiro, Karen G. N., Silva, Ítala C., Gonçalves, Sónia, Lu, Timothy K., Santos, Nuno C., de la Fuente-Nunez, Cesar, Craik, David J. and Franco, Octávio L. (2022). An N-capping asparagine–lysine–proline (NKP) motif contributes to a hybrid flexible/stable multifunctional peptide scaffold. Chemical Science, 13 (32), 9410-9424. doi: 10.1039/d1sc06998e |
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2022 Book Chapter Scalable and efficient In planta biosynthesis of sunflower trypsin inhibitor-1 (SFTI) peptide therapeuticsHandley, Thomas N. G., Jackson, Mark A. and Craik, David J. (2022). Scalable and efficient In planta biosynthesis of sunflower trypsin inhibitor-1 (SFTI) peptide therapeutics. Peptide macrocycles: methods and protocols. (pp. 117-142) edited by Matthew B. Coppock and Alexander J. Winton. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-1689-5_7 |
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2022 Other Outputs De novo design of peptide-small molecule ligands of the kappa-opioid receptorsMuratspahic, E., Muttenthaler, M., Jadhav, K. B., Baker, D., Che, T., Spetea, M., Craik, D. and Gruber, C. W. (2022). De novo design of peptide-small molecule ligands of the kappa-opioid receptors. EP22193238. |
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2021 Conference Publication An N-capping asparagine-lysine-proline (NKP) motif contributes to a hybrid flexible/stable multifunctional peptide scaffoldSilva Cardoso, Marlon Henrique E., Chan, Lai Yue, Candido, Elizabete De Souza, Torres, Marcelo D. T., Oshiro, Karen G. N., Silva, Itala C., Goncalves, S., Buccini, Danieli Fernanda, Lu, Timothy K., Santos, Nuno C., De la Fuente-Nunez, Cesar, Craik, David J. and Franco, Octavio L. (2021). An N-capping asparagine-lysine-proline (NKP) motif contributes to a hybrid flexible/stable multifunctional peptide scaffold. 20th IUPAB International Congress, 45th SBBf Congress and 50th Annual Meeting of SBBq, Online, 4-8 October 2021. London, United Kingdom: Springer. |
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2021 Conference Publication Optimising peptide cyclisation pathways in Nicotiana benthamiana enables plant molecular farming of therapeutic peptidesJackson, M.A, Gilding, E.K, Chan, L.Y, Harding, M. and Craik, D.J (2021). Optimising peptide cyclisation pathways in Nicotiana benthamiana enables plant molecular farming of therapeutic peptides. Australian Society for Plant Scientist, Adelaide, VIC, Australia, 25 - 26 November 2021. |
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2021 Journal Article Evaluation of efficient non-reducing enzymatic and chemical ligation strategies for complex disulfide-rich peptidesTran, Hue N. T., Tran, Poanna, Deuis, Jennifer R., McMahon, Kirsten L., Yap, Kuok, Craik, David J., Vetter, Irina and Schroeder, Christina I. (2021). Evaluation of efficient non-reducing enzymatic and chemical ligation strategies for complex disulfide-rich peptides. Bioconjugate Chemistry, 32 (11) acs.bioconjchem.1c00452, 2407-2419. doi: 10.1021/acs.bioconjchem.1c00452 |
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Featured 2021 Journal Article Enabling efficient folding and high-resolution crystallographic analysis of bracelet cyclotidesHuang, Yen-Hua, Du, Qingdan, Jiang, Zhihao, King, Gordon J., Collins, Brett M., Wang, Conan K. and Craik, David J. (2021). Enabling efficient folding and high-resolution crystallographic analysis of bracelet cyclotides. Molecules, 26 (18) 5554, 5554. doi: 10.3390/molecules26185554 |
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2021 Journal Article Interactions of globular and ribbon [γ4E]GID with α4β2 neuronal nicotinic acetylcholine receptorWu, Xiaosa, Craik, David J. and Kaas, Quentin (2021). Interactions of globular and ribbon [γ4E]GID with α4β2 neuronal nicotinic acetylcholine receptor. Marine Drugs, 19 (9) 482, 482. doi: 10.3390/md19090482 |
