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2025 Conference Publication Recombinant production of an antimalarial peptide in Nicotiana benthamianaNguyen, Linh T.T., Harding, Maxim D., Healy, Wing L., Thanthrige, Nipuni P., Ninh, Thao T., Jackson, Mark A., Gilding, Edward K., Lawrence, Nicole and Craik, David (2025). Recombinant production of an antimalarial peptide in Nicotiana benthamiana. The 16th Australian Peptide Conference, Launceston, TAS, Australia, 12-17 October 2025. |
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2025 Journal Article Design of Bicyclic peptide tandems mimicking the homodimeric GDF15 protein to inhibit GDF15–GFRaL–RET complex cell signalingNoisier, Anaïs F. M., Sandmark, Jenny, Edfeldt, Fredrik, Backmark, Anna, Broddefalk, Johan, Wandzik, Joanna, Jurva, Ulrik, Ek, Margareta, Johansson, Carina A., Barlind, Louise, Gunnarsson, Jenny, Bigalke, Janna M., Xue, Yafeng, Frolov, Andrey I., Kankkonen, Cecilia, Roth, Robert G., Fritsch, Maria, Watcham, Sophie, van Rietschoten, Katerine, Mudd, Gemma E., Harrison, Helen, Chen, Liuhong, Skynner, Michael J., Craik, David J., Chankeshwara, Sunay V. and Lemurell, Malin (2025). Design of Bicyclic peptide tandems mimicking the homodimeric GDF15 protein to inhibit GDF15–GFRaL–RET complex cell signaling. Journal of Medicinal Chemistry, 68 (20), 21441-21457. doi: 10.1021/acs.jmedchem.5c01378 |
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2025 Journal Article Where have you been? Backtracking microplastic to its source using the biomolecular composition of the ecocoronaDawson, Amanda L., Bose, Utpal, Escobar-Correas, Sophia, Yap, Kuok, Craik, David J. and Pegg, Cassandra L. (2025). Where have you been? Backtracking microplastic to its source using the biomolecular composition of the ecocorona. Environmental Science and Technology, 59 (41), 22227-22238. doi: 10.1021/acs.est.5c09277 |
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2025 Journal Article AEP-mediated backbone cyclization of cyclotides—a chemoenzymatic method for cyclotide productionZhou, Yan, de Veer, Simon J., Durek, Thomas and Craik, David J. (2025). AEP-mediated backbone cyclization of cyclotides—a chemoenzymatic method for cyclotide production. Methods in Enzymology, 723, 71-90. doi: 10.1016/bs.mie.2025.09.001 |
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2025 Journal Article Mixed-chirality prohibitin peptide: D-(RLARLAR)2 enhances stability and in vivo effects on obesityChan, Lai Yue, Weger, Benjamin D., Weger, Meltem, Du, Junqiao, Lawrence, Nicole, Cardoso, Marlon H., de Rezende, Samilla B., Muller, Jéssica A.I., Yap, Kuok, Tse, Brian W−C., Sokolowski, Kamil A., Sullivan, Robert K.P., Gunter, Jennifer, Franco, Octávio L., Gachon, Frédéric and Craik, David J. (2025). Mixed-chirality prohibitin peptide: D-(RLARLAR)2 enhances stability and in vivo effects on obesity. Journal of the American Chemical Society, 147 (28), 24628-24642. doi: 10.1021/jacs.5c05536 |
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2025 Journal Article Asparaginyl ligases with engineered substrate specificity for controlled, sequential transpeptidation reactionsZhou, Yan, de Veer, Simon J., Tyler, Tristan J., Chen, Yufei, Durek, Thomas, Craik, David J. and Rehm, Fabian B. H. (2025). Asparaginyl ligases with engineered substrate specificity for controlled, sequential transpeptidation reactions. Journal of the American Chemical Society, 147 (25), 21824-21831. doi: 10.1021/jacs.5c04693 |
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2025 Journal Article High-throughput enrichment of functional disulfide-rich peptides by droplet microfluidicsXie, Jing, Yap, Kuok, de Veer, Simon J., Edwardraja, Selvakumar, Durek, Thomas, Trau, Matt, Craik, David J. and Wang, Conan K. (2025). High-throughput enrichment of functional disulfide-rich peptides by droplet microfluidics. Lab on a Chip, 25 (14), 3525-3536. doi: 10.1039/d5lc00261c |
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2025 Journal Article Cyclization of the analgesic α‐Conotoxin Vc1.1 with a non‐natural linker: effects on structure, stability, and bioactivityZhang, Yuhui, Tae, Han Shen, Adams, David J., Durek, Thomas and Craik, David J. (2025). Cyclization of the analgesic α‐Conotoxin Vc1.1 with a non‐natural linker: effects on structure, stability, and bioactivity. Journal of Peptide Science, 31 (6) e70017, 1-10. doi: 10.1002/psc.70017 |
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2025 Journal Article Exploring use of a protein cage system for producing bioactive peptides in Escherichia coliHarding, Maxim D., Jackson, Mark A., Gilding, Edward K., Yap, Kuok, Craik, David J., Sainsbury, Frank and Lawrence, Nicole (2025). Exploring use of a protein cage system for producing bioactive peptides in Escherichia coli. Microbial Biotechnology, 18 (6) e70158, 1-14. doi: 10.1111/1751-7915.70158 |
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2025 Journal Article An orthogonal protection strategy for the synthesis of conotoxins containing three disulfide bondsZhang, Hengyu, Chan, Lai Yue, Zhang, Huanhuan, Jiang, Tao, Craik, David J., Cai, Wenqing and Yu, Rilei (2025). An orthogonal protection strategy for the synthesis of conotoxins containing three disulfide bonds. Marine Drugs, 23 (4) 168, 1-11. doi: 10.3390/md23040168 |
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2025 Journal Article Anticoagulation during Extracorporeal Membrane Oxygenation (ECMO): A Selective Inhibitor of Activated Factor XII Compared to Heparin in an Ex Vivo ModelGandini, Lucia, de Veer, Simon J., Chan, Chris H. H., Passmore, Margaret R., Liu, Keibun, Lundon, Brooke, Rachakonda, Reema, White, Nicole, Rhodes, Madeleine, Shanahan, Emma, Yap, Kuok, See Hoe, Louise E., Semenzin, Clayton, Li Bassi, Gianluigi, Fraser, John F., Craik, David J. and Suen, Jacky Y. (2025). Anticoagulation during Extracorporeal Membrane Oxygenation (ECMO): A Selective Inhibitor of Activated Factor XII Compared to Heparin in an Ex Vivo Model. ACS Pharmacology & Translational Science, 8 (5), 1260-1269. doi: 10.1021/acsptsci.4c00352 |
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2025 Journal Article Selective inhibition of Rat α7 nicotinic acetylcholine receptors by LvID, a newly characterized α4/7-conotoxin from Conus lividusGuo, Man, Zhu, Xiaopeng, Ma, Tao, Xu, Chenxing, Zhangsun, Dongting, Yu, Jinpeng, Kaas, Quentin, Harvey, Peta J., McIntosh, J. Michael, Craik, David J. and Luo, Sulan (2025). Selective inhibition of Rat α7 nicotinic acetylcholine receptors by LvID, a newly characterized α4/7-conotoxin from Conus lividus. Journal of Medicinal Chemistry, 68 (8), 8163-8173. doi: 10.1021/acs.jmedchem.4c02810 |
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2025 Journal Article Cell-penetrating cyclic and disulfide-rich peptides are privileged molecular scaffolds for intracellular targetingTroeira Henriques, Sónia, Lawrence, Nicole, Kan, Meng-Wei, Malins, Lara R. and Craik, David J. (2025). Cell-penetrating cyclic and disulfide-rich peptides are privileged molecular scaffolds for intracellular targeting. Biochemistry, 64 (7), 1437-1449. doi: 10.1021/acs.biochem.4c00845 |
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2025 Journal Article Recombinant production of the cyclotide kalata B1 by conditional split inteinsCraik, David J., Yayci, Abdulkadir, Huang, Yen-Hua and Harvey, Peta J. (2025). Recombinant production of the cyclotide kalata B1 by conditional split inteins. ChemBioChem, 26 (4) e202400591, e202400591. doi: 10.1002/cbic.202400591 |
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2025 Journal Article The future of utilising semiochemical pest control methods to manage the destructive crown-of-thorns starfish outbreaks on coral reefsHarris, Richard J., Barnard, d'Artagnan L., Paxton, Gillian, Lockie, Stewart, Craik, David J., Cummins, Scott F., Wang, Conan K. and Motti, Cherie A. (2025). The future of utilising semiochemical pest control methods to manage the destructive crown-of-thorns starfish outbreaks on coral reefs. Biological Conservation, 302 110984, 110984-302. doi: 10.1016/j.biocon.2025.110984 |
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2025 Journal Article Exploring the utility of cell-penetrating peptides as vehicles for the delivery of distinct antimalarial drug cargoesGare, Caitlin L., Palombi, Isabella R., White, Andrew M., Chavchich, Marina, Edstein, Michael D., Lock, Aaron, Avery, Vicky M., Craik, David J., McMorran, Brendan J., Lawrence, Nicole and Malins, Lara Rebecca (2025). Exploring the utility of cell-penetrating peptides as vehicles for the delivery of distinct antimalarial drug cargoes. ChemMedChem, 20 (2) e202400637, e202400637. doi: 10.1002/cmdc.202400637 |
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2025 Book Chapter Advances in peptide-based drug discoveryKhatri, Bhavesh, Linhares Velloso, Joao Paulo, Shambhawi, Kan, Meng-Wei and Craik, David J. (2025). Advances in peptide-based drug discovery. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. (pp. 1-1) Amsterdam, Netherlands: Elsevier. doi: 10.1016/b978-0-443-29808-0.00041-8 |
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2025 Journal Article Synthesis and Investigation of Peptide-Drug Conjugates Comprising Camptothecin and a Human Protein-Derived Cell-Penetrating PeptidePalombi, Isabella R., White, Andrew M., Koda, Yasuko, Craik, David J., Lawrence, Nicole and Malins, Lara R. (2025). Synthesis and Investigation of Peptide-Drug Conjugates Comprising Camptothecin and a Human Protein-Derived Cell-Penetrating Peptide. Chemical Biology & Drug Design, 105 (1) e70051, 1-10. doi: 10.1111/cbdd.70051 |
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2025 Journal Article Analogs of cyclic peptide mortiamide‐d from marine fungi have improved membrane permeability and kill drug‐resistant melanoma cellsBergeron, Catherine, Bérubé, Christopher, Lamb, Henry, Koda, Yasuko, Craik, David J., Henriques, Sónia Troeira, Voyer, Normand and Lawrence, Nicole (2025). Analogs of cyclic peptide mortiamide‐d from marine fungi have improved membrane permeability and kill drug‐resistant melanoma cells. Peptide Science, 117 (1) e24380. doi: 10.1002/pep2.24380 |
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2025 Journal Article Recent progress on cyclotides: 2021-2024Kan, Meng-Wei, Roseli, Ras Baizureen, Chan, Lai Yue, Nguyen, Linh T. T. and Craik, David J. (2025). Recent progress on cyclotides: 2021-2024. ScienceAsia, 51S (1) 2025s009, 1-17. doi: 10.2306/scienceasia1513-1874.2025.s009 |
