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2025 Journal Article The future of utilising semiochemical pest control methods to manage the destructive crown-of-thorns starfish outbreaks on coral reefsHarris, Richard J., Barnard, d'Artagnan L., Paxton, Gillian, Lockie, Stewart, Craik, David J., Cummins, Scott F., Wang, Conan K. and Motti, Cherie A. (2025). The future of utilising semiochemical pest control methods to manage the destructive crown-of-thorns starfish outbreaks on coral reefs. Biological Conservation, 302 110984, 110984-302. doi: 10.1016/j.biocon.2025.110984 |
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2025 Journal Article Exploring the utility of cell-penetrating peptides as vehicles for the delivery of distinct antimalarial drug cargoesGare, Caitlin L., Palombi, Isabella R., White, Andrew M., Chavchich, Marina, Edstein, Michael D., Lock, Aaron, Avery, Vicky M., Craik, David J., McMorran, Brendan J., Lawrence, Nicole and Malins, Lara Rebecca (2025). Exploring the utility of cell-penetrating peptides as vehicles for the delivery of distinct antimalarial drug cargoes. ChemMedChem, 20 (2) e202400637, e202400637. doi: 10.1002/cmdc.202400637 |
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2025 Journal Article Recent progress on cyclotides: 2021-2024Kan, Meng-Wei, Roseli, Ras Baizureen, Chan, Lai Yue, Nguyen, Linh T. T. and Craik, David J. (2025). Recent progress on cyclotides: 2021-2024. ScienceAsia, 51S (1) 2025s009, 1-17. doi: 10.2306/scienceasia1513-1874.2025.s009 |
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2025 Journal Article Synthesis and Investigation of Peptide-Drug Conjugates Comprising Camptothecin and a Human Protein-Derived Cell-Penetrating PeptidePalombi, Isabella R., White, Andrew M., Koda, Yasuko, Craik, David J., Lawrence, Nicole and Malins, Lara R. (2025). Synthesis and Investigation of Peptide-Drug Conjugates Comprising Camptothecin and a Human Protein-Derived Cell-Penetrating Peptide. Chemical Biology & Drug Design, 105 (1) e70051, 1-10. doi: 10.1111/cbdd.70051 |
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2025 Journal Article High-throughput enrichment of functional disulfide-rich peptides by droplet microfluidicsXie, Jing, Yap, Kuok, de Veer, Simon J., Edwardraja, Selvakumar, Durek, Thomas, Trau, Matt, Craik, David J. and Wang, Conan K. (2025). High-throughput enrichment of functional disulfide-rich peptides by droplet microfluidics. Lab on a Chip, 25 (14), 3525-3536. doi: 10.1039/d5lc00261c |
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2025 Journal Article Analogs of cyclic peptide mortiamide‐d from marine fungi have improved membrane permeability and kill drug‐resistant melanoma cellsBergeron, Catherine, Bérubé, Christopher, Lamb, Henry, Koda, Yasuko, Craik, David J., Henriques, Sónia Troeira, Voyer, Normand and Lawrence, Nicole (2025). Analogs of cyclic peptide mortiamide‐d from marine fungi have improved membrane permeability and kill drug‐resistant melanoma cells. Peptide Science, 117 (1) e24380. doi: 10.1002/pep2.24380 |
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2024 Journal Article Highly Efficient Transpeptidase-Catalyzed Isopeptide Ligationde Veer, Simon J., Craik, David J. and Rehm, Fabian B. H. (2024). Highly Efficient Transpeptidase-Catalyzed Isopeptide Ligation. Journal of the American Chemical Society, 147 (1), 557-565. doi: 10.1021/jacs.4c11964 |
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2024 Journal Article Peptide PaDBS1R6 has potent antibacterial activity on clinical bacterial isolates and integrates an immunomodulatory peptide fragment within its sequenceRezende, Samilla B., Chan, Lai Yue, Oshiro, Karen G.N., Buccini, Danieli F., Leal, Ana Paula Ferreira, Ribeiro, Camila F., Souza, Carolina M., Brandão, Amanda L.O., Gonçalves, Regina M., Cândido, Elizabete S., Macedo, Maria L.R., Craik, David J., Franco, Octávio L. and Cardoso, Marlon H. (2024). Peptide PaDBS1R6 has potent antibacterial activity on clinical bacterial isolates and integrates an immunomodulatory peptide fragment within its sequence. Biochimica et Biophysica Acta (BBA) - General Subjects, 1868 (11) 130693, 1-13. doi: 10.1016/j.bbagen.2024.130693 |
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2024 Journal Article Discovery of five classes of bacterial defensins: ancestral precursors of defensins from eukarya?Cardoso, Marlon H., de Lima, Lucas R., Pires, Allan S., Maximiano, Mariana R., Harvey, Peta J., Freitas, Camila G., Costa, Rosiane A., Fensterseifer, Isabel C. M., Rigueiras, Pietra O., Migliolo, Ludovico, Porto, William F., Craik, David J. and Franco, Octávio L. (2024). Discovery of five classes of bacterial defensins: ancestral precursors of defensins from eukarya?. ACS Omega, 9 (45), 45297-45308. doi: 10.1021/acsomega.4c06956 |
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2024 Journal Article Gene-guided identifications of a structure-chimeric cyclotide viphi I from Viola philippica: potential functions against cadmium and nematodesZhang, Xiaojie, Chen, Ruohong, Shu, Haoyue, Liang, Peihui, Qin, Ting, Wang, Kemei, Guo, Aimin, Craik, David J., Liao, Bin and Zhang, Jun (2024). Gene-guided identifications of a structure-chimeric cyclotide viphi I from Viola philippica: potential functions against cadmium and nematodes. Plant Science, 347 112185, 112185. doi: 10.1016/j.plantsci.2024.112185 |
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2024 Journal Article Conotoxins targeting voltage-gated sodium ion channelsPei, Shengrong, Wang, Nan, Mei, Zaoli, Zhangsun, Dongting, Craik, David J., McIntosh, J. Michael, Zhu, Xiaopeng and Luo, Sulan (2024). Conotoxins targeting voltage-gated sodium ion channels. Pharmacological Reviews, 76 (5), 828-845. doi: 10.1124/pharmrev.123.000923 |
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2024 Journal Article Display technologies for expanding the pharmaceutical applications of cyclotidesXie, Jing, Kan, Meng‐Wei, de Veer, Simon J., Wang, Conan and Craik, David J. (2024). Display technologies for expanding the pharmaceutical applications of cyclotides. Israel Journal of Chemistry, 64 (8-9) e202400010. doi: 10.1002/ijch.202400010 |
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2024 Journal Article Cyclic tachyplesin I kills proliferative, non-proliferative and drug-resistant melanoma cells without inducing resistanceBenfield, Aurélie H., Vernen, Felicitas, Young, Reuben S. E., Nadal-Bufí, Ferran, Lamb, Henry, Hammerlindl, Heinz, Craik, David J., Schaider, Helmut, Lawrence, Nicole, Blanksby, Stephen J. and Henriques, Sónia Troeira (2024). Cyclic tachyplesin I kills proliferative, non-proliferative and drug-resistant melanoma cells without inducing resistance. Pharmacological Research, 207 107298, 107298. doi: 10.1016/j.phrs.2024.107298 |
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2024 Journal Article Author Correction: Repurposing a plant peptide cyclase for targeted lysine acylationRehm, Fabian B. H., Tyler, Tristan J., Zhou, Yan, Huang, Yen-Hua, Wang, Conan K., Lawrence, Nicole, Craik, David J. and Durek, Thomas (2024). Author Correction: Repurposing a plant peptide cyclase for targeted lysine acylation. Nature Chemistry, 16 (9), 1565-1565. doi: 10.1038/s41557-024-01625-7 |
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2024 Journal Article Hijacking of N-fixing legume albumin-1 genes enables the cyclization and stabilization of defense peptidesGilding, Edward K., Jackson, Mark A., Nguyen, Linh T. T., Hamilton, Brett R., Farquharson, Katherine A., Ho, Wing L., Yap, Kuok, Hogg, Carolyn J., Belov, Katherine and Craik, David J. (2024). Hijacking of N-fixing legume albumin-1 genes enables the cyclization and stabilization of defense peptides. Nature Communications, 15 (1) 6565, 6565. doi: 10.1038/s41467-024-50742-x |
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2024 Conference Publication Peptide-drug conjugates as a novel approach to antimalarial therapeuticsGare, Caitlin, Palombi, Isabella, White, Andrew, Lawrence, Nicole, Craik, David, McMorran, Brendan and Malins, Lara (2024). Peptide-drug conjugates as a novel approach to antimalarial therapeutics. 37th European Peptide Symposium 14th International Peptide Symposium, Florence, Italy, 25–29 August 2024. Oxford, United Kingdom: John Wiley & Sons. |
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2024 Conference Publication A chemo-enzymatic approach to produce a cyclic analogues of peptide drug leadsZhou, Yan, Harvey, Peta, Durek, Tom and Craik, David (2024). A chemo-enzymatic approach to produce a cyclic analogues of peptide drug leads. 37th European Peptide Symposium 14th International Peptide Symposium, Florence, Italy, 25-29 August 2024. Oxford, United Kingdom: John Wiley & Sons. |
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2024 Journal Article Enhancing the intrinsic antiplasmodial activity and improving the stability and selectivity of a tunable peptide scaffold derived from human platelet factor 4Lawrence, Nicole, Handley, Thomas N. G., de Veer, Simon J., Harding, Maxim D., Andraszek, Alicja, Hall, Lachlan, Raven, Karoline D., Duffy, Sandra, Avery, Vicky M., Craik, David J., Malins, Lara R. and McMorran, Brendan J. (2024). Enhancing the intrinsic antiplasmodial activity and improving the stability and selectivity of a tunable peptide scaffold derived from human platelet factor 4. ACS Infectious Diseases, 10 (8), 2899-2912. doi: 10.1021/acsinfecdis.4c00276 |
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2024 Conference Publication Improving stability enhances in vivo efficacy of a PCSK9 inhibitory peptideZhang, Yuhui, Wang, Li, Tombling, Benjamin, Lammi, Carmen, Huang, Yen-Hua, Yue, Li, Bartolomei, Martina, Hong, Bin, Craik, David and Wang, Conan (2024). Improving stability enhances in vivo efficacy of a PCSK9 inhibitory peptide. 37th European Peptide Symposium 14th International Peptide Symposium, Florence, Italy, 25-29 August 2024. Oxford, United Kingdom: John Wiley & Sons. |
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2024 Conference Publication Site-directed scanning mutagenesis reveals specific residues that enhance both the enduring stability and insecticidal efficacy of the cyclotide kalata B1Huang, Yen-Hua, Jiang, Zhihao, Yap, Kuok, Bigot, Aurelien, Kaas, Quentin, Wang, Conan and Craik, David (2024). Site-directed scanning mutagenesis reveals specific residues that enhance both the enduring stability and insecticidal efficacy of the cyclotide kalata B1. 37th European Peptide Symposium 14th International Peptide Symposium, Florence, Italy, 25-29 August 2024. Oxford, United Kingdom: John Wiley & Sons. |
