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2007 Journal Article G-protein-coupled receptor expression, function, and signaling in macrophagesLattin, J., Zidar, D., Schroder, K., Kellie, S., Hume, D. and Sweet, M. (2007). G-protein-coupled receptor expression, function, and signaling in macrophages. Journal of Leukocyte Biology, 82 (1), 16-32. doi: 10.1189/jlb.0107051 |
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2007 Journal Article Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammationForwood, J., Thakur, A., Guncar, G., Marfori, M., Mouradov, D., Meng, W., Robinson, J., Huber, T., Kellie, S., Martin, J. L., Hume, D. and Kobe, B. (2007). Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation. Proceedings of The National Academy of Sciences of The United States of America, 104 (25), 10382-10387. doi: 10.1073/pnas.0700974104 |
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2007 Journal Article The role of schlafen in macrophages and inflammationvan Zuijlen, WJM, Cook, AD, Ovchinnikov, DA, Kellie, S and Hume, DA (2007). The role of schlafen in macrophages and inflammation. Inflammation Research, 56, S389-S389. |
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2007 Journal Article Neutrophilic schizophrenia: Breaching the barrier between innate and adaptive immunityFerrante, Antonio, Hii, Charles and Hume, David (2007). Neutrophilic schizophrenia: Breaching the barrier between innate and adaptive immunity. Immunology and Cell Biology, 85 (4), 265-266. doi: 10.1038/sj.icb.7100036 |
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2007 Journal Article PU.1 and ICSBP control constitutive and IFN-gamma-regulated Tlr9 gene expression in mouse macrophagesSchroder, Kate, Lichtinger, Monika, Irvine, Katharine M., Brion, Kristian, Trieu, Angela, Ross, Ian L., Ravasi, Timothy, Stacey, Katryn J., Rehli, Michael, Hume, David A. and Sweet, Matthew J. (2007). PU.1 and ICSBP control constitutive and IFN-gamma-regulated Tlr9 gene expression in mouse macrophages. Journal of Leukocyte Biology, 81 (6), 1577-1590. doi: 10.1189/jlb.0107036 |
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2007 Journal Article Gpnmb is induced in macrophages by IFN-gamma and lipopolysaccharide and acts as a feedback regulator of proinflammatory responsesRipoll, Vera M., Irvine, Katharine M., Ravasi, Timothy, Sweet, Matthew J. and Hume, David A. (2007). Gpnmb is induced in macrophages by IFN-gamma and lipopolysaccharide and acts as a feedback regulator of proinflammatory responses. Journal of Immunology, 178 (10), 6557-6566. doi: 10.4049/jimmunol.178.10.6557 |
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2007 Journal Article The expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factorMeadows, Nicholas A., Sharma, Sudarshana M., Faulkner, Geoffrey J., Ostrowski, Michael C., Hume, David A. and Cassady, Alan I. (2007). The expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factor. Journal of Biological Chemistry, 282 (3), 1891-1904. doi: 10.1074/jbc.M608572200 |
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2007 Journal Article Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitmentBode, K. A., Schroder, K., Hume, D. A., Ravasi, T., Heeg, K., Sweet, M. J. and Dalpke, A. H. (2007). Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment. Immunology, 122 (4), 596-606. doi: 10.1111/j.1365-2567.2007.02678.x |
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2007 Journal Article S100A8/S100A9 and their association with cartilage and boneZreiqat, H., Howlett, C.R., Gronthos, S., Hume, D. and Geczy, C.L. (2007). S100A8/S100A9 and their association with cartilage and bone. Journal of Molecular Histology, 38 (5), 381-391. doi: 10.1007/s10735-007-9117-2 |
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2007 Journal Article Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1Sasmono, R. T., Ehrnsperger, A., Cronau, S. L., Ravasi, T., Kandane, R., Hickey, M. J., Cook, A. D., Himes, S. R., Hamilton, J. A. and Hume, D. A. (2007). Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1. Journal of Leukocyte Biology, 82 (1), 111-123. doi: 10.1189/jlb.1206713 |
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2007 Journal Article Mammalian RNA polymerase II core promoters: insights from genome-wide studiesSandelin, A, Carninci, P, Lenhard, B, Ponjavic, J, Hayashizaki, Y and Hume, DA (2007). Mammalian RNA polymerase II core promoters: insights from genome-wide studies. Nature Reviews Genetics, 8 (6), 424-436. doi: 10.1038/nrg2026 |
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2007 Journal Article Concordant Epigenetic silencing of transforming growth factor -beta signalling pathway genes occurs early in breast carcinogenesisHinshelwood, Rebecca A., Huschtscha, Lily I., Melki, John, Stirzaker, Clare, Abdipranoto, Andrea, Vissel, Bryce, Ravasi, Timothy, Wells, Christine A., Hume, David A., Reddel, Roger R. and Clark, Susan J. (2007). Concordant Epigenetic silencing of transforming growth factor -beta signalling pathway genes occurs early in breast carcinogenesis. Cancer Research, 67 (24), 11517-11527. doi: 10.1158/0008-5472.CAN-07-1284 |
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2007 Journal Article Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporterRae, Fiona, Woods, Kyra, Sasmono, Tedjo, Campanale, Naomi, Taylor, Darrin, Ovchinnikov, Dmitry A., Grimmond, Sean M., Hume, David A., Ricardo, Sharon D. and Little, Melissa H. (2007). Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporter. Developmental Biology, 308 (1), 232-246. doi: 10.1016/j.ydbio.2007.05.027 |
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2006 Journal Article CpG DNA activates survival in murine macrophages through TLR9 and the phosphatidylinositol 3-kinase-Akt pathwaySester, D. P., Brion, K., Trieu, A., Goodridge, H. S., Roberts, T. L., Dunn, J., Hume, D. A., Stacey, K. J. and Sweet, M. J. (2006). CpG DNA activates survival in murine macrophages through TLR9 and the phosphatidylinositol 3-kinase-Akt pathway. Journal of Immunology, 177 (7), 4473-4480. doi: 10.4049/jimmunol.177.7.4473 |
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2006 Journal Article A CSF-1 receptor kinase inhibitor targets effector functions and inhibits pro-inflammatory cytokine production from murine macrophage populationsIrvine, Katharine M., Burns, Christopher J., Wilks, Andrew F., Su, Stephen, Hume, David A. and Sweet, Matthew J. (2006). A CSF-1 receptor kinase inhibitor targets effector functions and inhibits pro-inflammatory cytokine production from murine macrophage populations. The FASEB Journal, 20 (11), 1921-1923. doi: 10.1096/fj.06-5848fje |
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2006 Journal Article Macrophage-specific expression of human lysosomal acid lipase corrects inflammation and pathogenic phenotypes in lal(-/-) miceYan, Cong, Lian, Xuemei, Li, Yuan, Dai, Ying, White, Amanda, Qin, Yulin, Li, Huimin, Hume, David A. and Du, Hong (2006). Macrophage-specific expression of human lysosomal acid lipase corrects inflammation and pathogenic phenotypes in lal(-/-) mice. American Journal of Pathology, 169 (3), 916-926. doi: 10.2353/ajpath.2006.051327 |
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2006 Journal Article Comment on "CCR7 is critically important for migration of dendritic cells in intestinal lamina propria to mesenteric lymph nodes"Hume, David A. (2006). Comment on "CCR7 is critically important for migration of dendritic cells in intestinal lamina propria to mesenteric lymph nodes". Journal of Immunology, 177 (4), 2035-2035. doi: 10.4049/jimmunol.177.4.2035 |
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2006 Journal Article Transcriptional network dynamics in macrophage activationNilsson, Roland, Bajic, Vladimir B., Suzuki, Harukazu, di Bernardo, Diego, Bjorkegren, Johan, Katayama, Shintaro, Reid, James F., Sweet, Matthew J., Gariboldi, Manuela, Carninci, Piero, Hayashizaki, Yosihide, Hume, David A., Tegner, Jesper and Ravasi, Timothy (2006). Transcriptional network dynamics in macrophage activation. Genomics, 88 (2), 133-142. doi: 10.1016/j.ygeno.2006.03.022 |
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2006 Journal Article Mice and men: Their promoter propertiesBajic, Vladimir B., Tan, Sin Lam, Christoffels, Alan, Schonbach, Christian, Lilpovich, Leonard, Yang, Liang, Hofmann, Oliver, Kruger, Adele, Hide, Winston, Kai, Chikatoshi, Kawai, Jun, Hume, David A., Carninci, Piero and Hayashizaki, Yoshihide (2006). Mice and men: Their promoter properties. Plos Genetics, 2 (4) e54, 614-626. doi: 10.1371/journal.pgen.0020054 |
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2006 Journal Article Transcript annotation in FANTOM3: Mouse gene catalog based on physical cDNAsMaeda, Norihiro, Kasukawa,Takeya, Frith, Martin, Aturaliya, Rajith N., Forrest, Alistair R. R., Ravasi,Timothy, Teasdale, Rohan D., Wells, Christine A., Hume,David A. and Hayashizaki,Yoshihide (2006). Transcript annotation in FANTOM3: Mouse gene catalog based on physical cDNAs. PLoS Genetics, 2 (4) e62, 498-503. doi: 10.1371/journal.pgen.0020062 |
