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2006

Journal Article

Alternate transcription of the Toll-like receptor signaling cascade

Wells, C. A., Chalk, A. M., Forrest, A., Taylor, D., Waddell, N., Schroder, K., Himes, S. R., Faulkner, G., Lo, S., Kasukawa, T., Kawaji, H., Kai, C., Kawai, J., Katayama, S., Carninci, P., Hayashizaki, Y., Hume, D. A. and Grimmond, S. M. (2006). Alternate transcription of the Toll-like receptor signaling cascade. Genome Biology, 7 (2) R10, R10.1-R10.17. doi: 10.1186/gb-2006-7-2-r10

Alternate transcription of the Toll-like receptor signaling cascade

2006

Journal Article

The JNK are important for development and survival of macrophages

Himes, S. Roy, Sester, David P., Ravasi, Timothy, Cronau, Stephen L., Sasmono, Tedjo and Hume, David A. (2006). The JNK are important for development and survival of macrophages. Journal Of Immunology, 176 (4), 2219-2228. doi: 10.4049/jimmunol.176.4.2219

The JNK are important for development and survival of macrophages

2006

Journal Article

Innate immunity

Hume, David and Hertzog, Paul (2006). Innate immunity. Current Opinion in Immunology, 18 (1), 1-2. doi: 10.1016/j.coi.2005.11.016

Innate immunity

2006

Journal Article

LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression

Aung, H. T., Schroder, K., Himes, S. R., Brion, K., van Zuylen, W., Trieu, A., Suzuki, H., Hayashizaki, Y., Hume, D. A., Sweet, M. J. and Ravasi, T. (2006). LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression. Faseb Journal, 20 (9), 1315-1327. doi: 10.1096/fj.05-5360com

LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression

2006

Journal Article

Genome-wide analysis of mammalian promoter architecture and evolution

Carninci, Piero, Sandelin, Albin, Lenhard, Boris, Frith, Martin C., Forrest, Alistair R. R., Ravasi, Timothy, Grimmond, Sean M., Wells, Christine A., Hume, David A. and Hayashizaki, Yoshihide (2006). Genome-wide analysis of mammalian promoter architecture and evolution. Nature Genetics, 38 (6), 626-635. doi: 10.1038/ng1789

Genome-wide analysis of mammalian promoter architecture and evolution

2006

Journal Article

Reduction of the in vitro pro-inflammatory response by macrophages to poly(3-hydroxybutyrate-co-3-hydroxyvalerate)

Wu, Andy C. K., Grondahl, Lisbeth, Jack, Kevin S., Foo, Michelle X., Trau, Matt, Hume, David A. and Cassady, Alan I. (2006). Reduction of the in vitro pro-inflammatory response by macrophages to poly(3-hydroxybutyrate-co-3-hydroxyvalerate). Biomaterials, 27 (27), 4715-4725. doi: 10.1016/j.biomaterials.2006.05.010

Reduction of the in vitro pro-inflammatory response by macrophages to poly(3-hydroxybutyrate-co-3-hydroxyvalerate)

2006

Journal Article

Apoptotic cell removal in development and tissue homeostasis

Henson, P. M. and Hume, D. A. (2006). Apoptotic cell removal in development and tissue homeostasis. Trends In Immunology, 27 (5), 244-250. doi: 10.1016/j.it.2006.03.005

Apoptotic cell removal in development and tissue homeostasis

2006

Journal Article

Modelling the structure of latexin-carboxypeptidase A complex based on chemical cross-linking and molecular docking

Mouradov, D., Craven, A., Forwood, J. K., Flanagan, J. U., Garcia-Castellanos, R., Gomis-Ruth, F. X., Hume, D. A., Martin, J. L., Kobe, B. and Huber, T. (2006). Modelling the structure of latexin-carboxypeptidase A complex based on chemical cross-linking and molecular docking. Protein Engineering Design & Selection, 19 (1), 9-16. doi: 10.1093/protein/gzi070

Modelling the structure of latexin-carboxypeptidase A complex based on chemical cross-linking and molecular docking

2006

Journal Article

Signal integration between IFN gamma and TLR signalling pathways in macrophages

Schroder, K., Sweet, M. J. and Hume, D. A. (2006). Signal integration between IFN gamma and TLR signalling pathways in macrophages. Immunobiology, 211 (6-8), 511-524. doi: 10.1016/j.imbio.2006.05.007

Signal integration between IFN gamma and TLR signalling pathways in macrophages

2006

Journal Article

Experimental validation of the regulated expression of large numbers of non-coding RNAs from the mouse genome

Ravasi, T., Suzuki, H., Pang, K. C., Katayama, S., Furuno, M., Okunishi, R., Fukuda, S., Ru, K., Frith, M., Gongora, M., Grimmond, S., Hume, D. A., Hayashizaki, Y. and Mattick, J. S. (2006). Experimental validation of the regulated expression of large numbers of non-coding RNAs from the mouse genome. Genome Research, 16 (1), 11-19. doi: 10.1101/gr.4200206

Experimental validation of the regulated expression of large numbers of non-coding RNAs from the mouse genome

2006

Journal Article

Histone Deacetylase Inhibitor Reduces Monocyte Adhesion to Endothelium Through the Suppression of Vascular Cell Adhesion Molecule-1 Expression

Inoue, Kenji, Kobayashi, Mika, Yano, Kiichiro, Miura, Mai, Izumi, Akashi, Mataki, Chikage, Doi, Takeshi, Hamakubo, Takao, Reid, Patrick C., Hume, David A., Yoshida, Minoru, Aird, William C., Kodama, Tatsuhiko and Minami, Takashi (2006). Histone Deacetylase Inhibitor Reduces Monocyte Adhesion to Endothelium Through the Suppression of Vascular Cell Adhesion Molecule-1 Expression. Arteriosclerosis Thrombosis And Vascular Biology, 26 (12), 2652-2659. doi: 10.1161/01.ATV.0000247247.89787.e7

Histone Deacetylase Inhibitor Reduces Monocyte Adhesion to Endothelium Through the Suppression of Vascular Cell Adhesion Molecule-1 Expression

2006

Journal Article

Crystallization of the C-terminal domain of the mouse brain cytosolic long-chain acyl-CoA thioesterase

Serek, R., Forwood, J. K., Hume, D. A., Martin, J. L. and Kobe, B. (2006). Crystallization of the C-terminal domain of the mouse brain cytosolic long-chain acyl-CoA thioesterase. Acta Crystallographica Section F-structural Biology And Crystallization Communications, 62, 133-135. doi: 10.1107/S17443091060000030

Crystallization of the C-terminal domain of the mouse brain cytosolic long-chain acyl-CoA thioesterase

2006

Journal Article

Identification and molecular modeling of a novel, plant-like, human purple acid phosphatase

Flanagan, J. U., Cassady, A. I., Schenk, G., Guddat, L. W. and Hume, D. A. (2006). Identification and molecular modeling of a novel, plant-like, human purple acid phosphatase. Gene, 377 (1), 12-20. doi: 10.1016/j.gene.2006.02.031

Identification and molecular modeling of a novel, plant-like, human purple acid phosphatase

2006

Journal Article

Genetics and genomics of osteoclast differentiation: Integrating cell signaling pathways and gene networks

Sharma, S. M., Hu, R., Bronisz, A., Meadows, N., Lusby, T., Fletcher, B., Hume, D. A., Cassady, A. I. and Ostrowski, M. C. (2006). Genetics and genomics of osteoclast differentiation: Integrating cell signaling pathways and gene networks. Critical Reviews In Eukaryotic Gene Expression, 16 (3), 253-277. doi: 10.1615/critreveukargeneexpr.v16.i3.40

Genetics and genomics of osteoclast differentiation: Integrating cell signaling pathways and gene networks

2006

Journal Article

Incorporating a TEV cleavage site reduces the solubility of nine recombinant mouse proteins

Kurz, M., Cowieson, N. P., Robin, G., Hume, D. A., Martin, J. L., Kobe, B. and Listwan, P. (2006). Incorporating a TEV cleavage site reduces the solubility of nine recombinant mouse proteins. Protein Expression And Purification, 50 (1), 68-73. doi: 10.1016/j.pep.2006.05.006

Incorporating a TEV cleavage site reduces the solubility of nine recombinant mouse proteins

2006

Journal Article

Computational promoter analysis of mouse, rat and human antimicrobial peptide-coding genes

Brahmachary, M., Schonbach, C., Yang, L., Huang, E. L., Tan, S. L., Chowdhary, R., Krishnan, S. P. T., Lin, C. Y., Hume, D. A., Kai, C., Kawai, J., Carninci, P., Hayashizaki, Y. and Bajic, V. B. (2006). Computational promoter analysis of mouse, rat and human antimicrobial peptide-coding genes. Bmc Bioinformatics, 7 (Supp. 5) S8, Article number S8. doi: 10.1186/1471-2105-7-S5-S8

Computational promoter analysis of mouse, rat and human antimicrobial peptide-coding genes

2006

Journal Article

An automatable screen for the rapid identification of proteins amenable to refolding

Cowieson, Nathan P., Wensley, Beth, Listwan, Pawel, Hume, David A., Kobe, Bostjan and Martin, Jennifer L. (2006). An automatable screen for the rapid identification of proteins amenable to refolding. Proteomics, 6 (6), 1750-1757. doi: 10.1002/pmic.200500056

An automatable screen for the rapid identification of proteins amenable to refolding

2006

Journal Article

The mononuclear phagocyte system

Hume, D. A. (2006). The mononuclear phagocyte system. Current Opinion In Immunology, 18 (1), 49-53. doi: 10.1016/j.coi.2005.11.008

The mononuclear phagocyte system

2006

Journal Article

Focusing in on structural genomics: The University of Queensland structural biology pipeline

Puri, M., Robin, G., Cowieson, N., Forwood, J. K., Listwan, P., Hu, S. H., Guncar, G., Huber, T., Kellie, S., Hume, D. A., Kobe, B. and Martin, J. L. (2006). Focusing in on structural genomics: The University of Queensland structural biology pipeline. Biomolecular Engineering, 23 (6), 281-289. doi: 10.1016/j.bioeng.2006.09.002

Focusing in on structural genomics: The University of Queensland structural biology pipeline

2005

Journal Article

Therapeutic targets in inflammatory disease

Hume, David A. and Fairlie, David P. (2005). Therapeutic targets in inflammatory disease. Current Medicinal Chemistry, 12 (25), 2925-2929. doi: 10.2174/092986705774462923

Therapeutic targets in inflammatory disease