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2009

Journal Article

Colony-stimulating factor-1 (CSF-1) delivers a proatherogenic signal to human macrophages

Irvine, Katharine M., Andrews, Melanie R., Fernandez-Rojo, Manuel A., Schroder, Kate, Burns, Christopher J., Su, Stephen, Wilks, Andrew F., Parton, Robert G., Hume, David A. and Sweet, Matthew J. (2009). Colony-stimulating factor-1 (CSF-1) delivers a proatherogenic signal to human macrophages. Journal of Leukocyte Biology, 85 (2), 278-288. doi: 10.1189/jlb.0808497

Colony-stimulating factor-1 (CSF-1) delivers a proatherogenic signal to human macrophages

2008

Journal Article

Our evolving knowledge of the transcriptional landscape

Hume, David A. (2008). Our evolving knowledge of the transcriptional landscape. Mammalian Genome, 19 (10-12), 663-666. doi: 10.1007/s00335-008-9140-y

Our evolving knowledge of the transcriptional landscape

2008

Journal Article

A rescue strategy for multimapping short sequence tags refines surveys of transcriptional activity by CAGE

Faulkner, G. J., Forrest, A. R. R., Chalk, A. M., Schroder, K., Hayashizaki, Y., Carninci, P., Hume, D. A. and Grimmond, S. M. (2008). A rescue strategy for multimapping short sequence tags refines surveys of transcriptional activity by CAGE. Genomics, 91 (3), 281-288. doi: 10.1016/j.ygeno.2007.11.003

A rescue strategy for multimapping short sequence tags refines surveys of transcriptional activity by CAGE

2008

Journal Article

Macrophages as APC and the dendritic cell myth

Hume, David A. (2008). Macrophages as APC and the dendritic cell myth. Journal of Immunology, 181 (9), 5829-5835. doi: 10.4049/jimmunol.181.9.5829

Macrophages as APC and the dendritic cell myth

2008

Journal Article

Osteal macrophages: A new twist on coupling during bone dynamics

Pettit, A. R., Chang, M. K., Hume, D. A. and Raggatt, L. J. (2008). Osteal macrophages: A new twist on coupling during bone dynamics. Bone, 43 (6), 976-982. doi: 10.1016/j.bone.2008.08.128

Osteal macrophages: A new twist on coupling during bone dynamics

2008

Journal Article

Identification of a non-purple tartrate-resistant acid phosphatase: An evolutionary link to Ser/Thr protein phosphatases?

Hadler, K.ieran S., Huber, Thomas, Cassady, A. Ian, Weber, Jane, Robinson, Jodie, Burrows, Allan, Kelly, Gregory, Guddat, Luke W., Hume, David A., Schenk, Gerhard and Flanagan, Jack U. (2008). Identification of a non-purple tartrate-resistant acid phosphatase: An evolutionary link to Ser/Thr protein phosphatases?. BMC Research Notes, 1 (1) 78, 1-8. doi: 10.1186/1756-0500-1-78

Identification of a non-purple tartrate-resistant acid phosphatase: An evolutionary link to Ser/Thr protein phosphatases?

2008

Journal Article

Identification of Disulfide-containing chemical cross-links in proteins using MALDI-TOF/TOF-MAss spectrometry

King, G. J., Jones, A., Kobe, B., Huber, T., Mouradov, D., Hume, D. A. and Ross, I. L. (2008). Identification of Disulfide-containing chemical cross-links in proteins using MALDI-TOF/TOF-MAss spectrometry. Analytical Chemistry, 80 (13), 5036-5043. doi: 10.1021/ac702277q

Identification of Disulfide-containing chemical cross-links in proteins using MALDI-TOF/TOF-MAss spectrometry

2008

Journal Article

Development of a DNA barcode tagging method for monitoring dynamic changes in gene expression by using an ultra high-throughput sequencer

Maeda, Norihiro, Nishiyori, Hiromi , Nakamura, Mari , Kawazu, Chika, Murata, Mitsuyoshi , Sano, Hiromi, Hayashida, Kengo, Fukuda, Shiro, Tagami, Michihira, Hasegawa, Akira, Murakami, Kayoko, Schroder, Kate, Irvine, Katharine, Hume, David A., Hayashizaki, Yoshihide, Carninci, Piero and Suzuki, Harukazu (2008). Development of a DNA barcode tagging method for monitoring dynamic changes in gene expression by using an ultra high-throughput sequencer. BioTechniques, 45 (1), 95-97. doi: 10.2144/000112814

Development of a DNA barcode tagging method for monitoring dynamic changes in gene expression by using an ultra high-throughput sequencer

2008

Journal Article

Cortactin adopts a globular conformation and bundles actin into sheets

Cowieson, Nathan P., King, Gordon, Cookson, David, Ross, Ian, Huber, Thomas, Hume, David A., Kobe, Bostjan and Martin, Jennifer L. (2008). Cortactin adopts a globular conformation and bundles actin into sheets. The Journal of Biological Chemistry, 283 (23), 16187-16193. doi: 10.1074/jbc.M708917200

Cortactin adopts a globular conformation and bundles actin into sheets

2008

Journal Article

The macrophage-inducible C-type lectin, Mincle, is an essential component of the innate immune response to Candida albicans

WellsChristineA, Salvage-JonesJudithA, LiXin, HitchensKelly, ButcherSuzanne, MurrayRachaelZ, Beckhouse, Anthony G., LoYu-Lan-Sandra, ManzaneroSilvia, CobboldChristian, SchroderKate, MaBo, OrrSally, StewartLauren, LebusDaniel, SobieszczukPeter, HumeDavidA, StowJennifer, BlanchardHelen, AshmanRobertB, RRich and MHogan (2008). The macrophage-inducible C-type lectin, Mincle, is an essential component of the innate immune response to Candida albicans. Journal of Immunology, 180 (11), 7404-7413. doi: 10.4049/jimmunol.180.11.7404

The macrophage-inducible C-type lectin, Mincle, is an essential component of the innate immune response to Candida albicans

2008

Journal Article

Increased TNF expression in CD43++ murine blood monocytes

Burke, Bernard, Ahmad, Rasheedah, Staples, Karl J., Snowden, Roger, Kadioglu, Aras, Frankenberger, Marion, Hume, David A. and Ziegler-Heitbrock, Loems (2008). Increased TNF expression in CD43++ murine blood monocytes. Immunology Letters, 118 (2), 142-147. doi: 10.1016/j.imlet.2008.03.012

Increased TNF expression in CD43++ murine blood monocytes

2008

Journal Article

The Ewing sarcoma protein (EWS) binds directly to the proximal elements of the macrophage-specific promoter of the CSF-1 receptor (csf1r) gene

Hume, David A., Sasmono, Tedjo, Himes, S. Roy, Sharma, Sudarshana M., Bronisz, Agnieszka, Constantin, Myrna, Ostrowski, Michael C. and Ross, Ian L. (2008). The Ewing sarcoma protein (EWS) binds directly to the proximal elements of the macrophage-specific promoter of the CSF-1 receptor (csf1r) gene. The Journal of Immunology, 180 (10), 6733-6742. doi: 10.4049/jimmunol.180.10.6733

The Ewing sarcoma protein (EWS) binds directly to the proximal elements of the macrophage-specific promoter of the CSF-1 receptor (csf1r) gene

2008

Journal Article

Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and In Vivo

Chang, Ming K., Raggatt, Liza-Jane, Alexander, Kylie A., Kuliwaba, Julia S., Fazzalari, Nicola L., Schroder, Kate, Maylin, Erin R., Ripoll, Vera M, Hume, David A. and Pettit, Allison R. (2008). Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and In Vivo. The Journal of Immunology, 181 (2), 1232-1244. doi: 10.4049/jimmunol.181.2.1232

Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and In Vivo

2008

Journal Article

Expression analysis of G Protein-coupled receptors in mouse macrophages

Lattin, Jane E., Schroder, Kate, Su, Andrew I., Walker, John R., Zhang, Jie, Wiltshire, Tim, Saijo, Kaoru, Glass, Christopher K., Hume, David A., Kellie, Stuart and Sweet, Matthew J. (2008). Expression analysis of G Protein-coupled receptors in mouse macrophages. Immunome Research, 4 (5) 5, 5. doi: 10.1186/1745-7580-4-5

Expression analysis of G Protein-coupled receptors in mouse macrophages

2008

Journal Article

Re: Structural and cellular differences between metaphyseal and diaphyseal periosteum in different-aged rats

Pettit, Allison R., Hume, David A. and Raggatt, Liza-Jane (2008). Re: Structural and cellular differences between metaphyseal and diaphyseal periosteum in different-aged rats. Bone, 42 (4), 825-825. doi: 10.1016/j.bone.2007.12.217

Re: Structural and cellular differences between metaphyseal and diaphyseal periosteum in different-aged rats

2008

Journal Article

Monomeric tartrate resistant acid phosphatase induces insulin sensitive obesity

Lang, P., Van Harmelen, V., Kaaman, M., Parini, P., Carneheim, C., Cassady, A. I., Hume, D. A., Andersson, G. and Arner, P. (2008). Monomeric tartrate resistant acid phosphatase induces insulin sensitive obesity. PLoS One, 3 (3) e1713, e1713-e1713. doi: 10.1371/journal.pone.0001713

Monomeric tartrate resistant acid phosphatase induces insulin sensitive obesity

2008

Journal Article

Expression of Gal4-dependent transgenes in cells of the mononuclear phagocyte system labeled with enhanced cyan fluorescent protein using Csf1r-Gal4VP16/UAS-ECFP double-transgenic mice

Ovchinnikov, Dmitry A., van Zuylen, Wendy J. M., DeBats, Claire E. E., Alexander, Kylie A., Kellie, Stuart and Hume, David A. (2008). Expression of Gal4-dependent transgenes in cells of the mononuclear phagocyte system labeled with enhanced cyan fluorescent protein using Csf1r-Gal4VP16/UAS-ECFP double-transgenic mice. Journal of Leukocyte Biology, 83 (2), 430-433. doi: 10.1189/jlb.0807585

Expression of Gal4-dependent transgenes in cells of the mononuclear phagocyte system labeled with enhanced cyan fluorescent protein using Csf1r-Gal4VP16/UAS-ECFP double-transgenic mice

2008

Journal Article

Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB

Ripoll, V. M, Meadows, N. A., Raggatt, L. J., Chang, M. K., Pettit, A. R., Cassady, A. I. and Hume, D. A. (2008). Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB. Gene, 413 (1-2), 32-41. doi: 10.1016/j.gene.2008.01.014

Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB

2008

Journal Article

Bring out your dead

Hume, David A. (2008). Bring out your dead. Nature Immunology, 9 (1), 12-14. doi: 10.1038/ni0108-12

Bring out your dead

2008

Journal Article

The transcriptional regulation of the Colony-Stimulating Factor 1 Receptor (csf1r) gene during hematopoiesis

Bonifer, Constanze and Hume, David A. (2008). The transcriptional regulation of the Colony-Stimulating Factor 1 Receptor (csf1r) gene during hematopoiesis. Frontiers in Bioscience-Landmark, 13 (2), 549-560. doi: 10.2741/2700

The transcriptional regulation of the Colony-Stimulating Factor 1 Receptor (csf1r) gene during hematopoiesis