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2020 Journal Article Species-specificity of transcriptional regulation and the response to lipopolysaccharide in mammalian macrophagesBush, Stephen J., McCulloch, Mary E. B., Lisowski, Zofia M., Muriuki, Charity, Clark, Emily L., Young, Rachel, Pridans, Clare, Prendergast, James G. D., Summers, Kim M. and Hume, David A. (2020). Species-specificity of transcriptional regulation and the response to lipopolysaccharide in mammalian macrophages. Frontiers in Cell and Developmental Biology, 8 661. doi: 10.3389/fcell.2020.00661 |
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2020 Journal Article The transcriptional network that controls growth arrest and macrophage differentiation in the human myeloid leukemia cell line THP-1Gažová, Iveta, Lefevre, Lucas, Bush, Stephen J., Clohisey, Sara, Arner, Erik, de Hoon, Michiel, Severin, Jessica, van Duin, Lucas, Andersson, Robin, Lengeling, Andreas, Hume, David A. and Summers, Kim M. (2020). The transcriptional network that controls growth arrest and macrophage differentiation in the human myeloid leukemia cell line THP-1. Frontiers in Cell and Developmental Biology, 8 498. doi: 10.3389/fcell.2020.00498 |
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2020 Journal Article An improved pig reference genome sequence to enable pig genetics and genomics researchWarr, Amanda, Affara, Nabeel, Aken, Bronwen, Beiki, Hamid, Bickhart, Derek M., Billis, Konstantinos, Chow, William, Eory, Lel, Finlayson, Heather A., Flicek, Paul, Girón, Carlos G., Griffin, Darren K., Hall, Richard, Hannum, Greg, Hourlier, Thibaut, Howe, Kerstin, Hume, David A., Izuogu, Osagie, Kim, Kristi, Koren, Sergey, Liu, Haibou, Manchanda, Nancy, Martin, Fergal J., Nonneman, Dan J., O'Connor, Rebecca E., Phillippy, Adam M., Rohrer, Gary A., Rosen, Benjamin D., Rund, Laurie A. ... Archibald, Alan L. (2020). An improved pig reference genome sequence to enable pig genetics and genomics research. GigaScience, 9 (6) GIAA051. doi: 10.1093/gigascience/giaa051 |
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2020 Journal Article Effects of immunomodulatory drugs on depressive symptoms: A mega-analysis of randomized, placebo-controlled clinical trials in inflammatory disordersWittenberg, Gayle M., Stylianou, Annie, Zhang, Yun, Sun, Yu, Gupta, Ashutosh, Jagannatha, P. S., Wang, Dai, Hsu, Benjamin, Curran, Mark E., Khan, Shahid, Vértes, Petra E., Cardinal, Rudolf, Richardson, Sylvia, Leday, Gwenael, Freeman, Tom, Hume, David, Regan, Tim, Wu, Zhaozong, Pariante, Carmine, Cattaneo, Annamaria, Zunszain, Patricia, Borsini, Alessandra, Stewart, Robert, Chandran, David, Carvalho, Livia, Bell, Joshua, Souza-Teodoro, Luis Henrique, Perry, Hugh, Harrison, Neil ... MRC ImmunoPsychiatry Consortium (2020). Effects of immunomodulatory drugs on depressive symptoms: A mega-analysis of randomized, placebo-controlled clinical trials in inflammatory disorders. Molecular Psychiatry, 25 (6), 1275-1285. doi: 10.1038/s41380-019-0471-8 |
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2020 Journal Article Comprehensive characterization of transcriptional activity during influenza A virus infection reveals biases in cap-snatching of host RNA sequencesClohisey, Sara, Parkinson, Nicholas, Wang, Bo, Bertin, Nicolas, Wise, Helen, Tomoiu, Andru, Summers, Kim M., Hendry, Ross W., Carninci, Piero, Forrest, Alistair R. R., Hayashizaki, Yoshihide, Digard, Paul, Hume, David A. and Baillie, J. Kenneth (2020). Comprehensive characterization of transcriptional activity during influenza A virus infection reveals biases in cap-snatching of host RNA sequences. Journal of Virology, 94 (10) e01720-19. doi: 10.1128/JVI.01720-19 |
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2020 Journal Article Regulation and function of macrophage colony-stimulating factor (CSF1) in the chicken immune systemWu, Zhiguang, Harne, Rakhi, Chintoan-Uta, Cosmin, Hu, Tuan-Jun, Wallace, Robert, MacCallum, Amanda, Stevens, Mark P., Kaiser, Pete, Balic, Adam and Hume, David A. (2020). Regulation and function of macrophage colony-stimulating factor (CSF1) in the chicken immune system. Developmental and Comparative Immunology, 105 103586, 103586. doi: 10.1016/j.dci.2019.103586 |
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2020 Journal Article Poincaré profiles of groups and spacesHume, David, Mackay, John M. and Tessera, Romain (2020). Poincaré profiles of groups and spaces. Revista Matematica Iberoamericana, 36 (6), 1835-1886. doi: 10.4171/RMI/1184 |
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2020 Journal Article Functional annotation of the transcriptome of the pig, Sus scrofa, based upon network analysis of an RNAseq transcriptional atlasSummers, Kim M., Bush, Stephen J., Wu, Chunlei, Su, Andrew I., Muriuki, Charity, Clark, Emily L., Finlayson, Heather A., Eory, Lel, Waddell, Lindsey A., Talbot, Richard, Archibald, Alan L. and Hume, David A. (2020). Functional annotation of the transcriptome of the pig, Sus scrofa, based upon network analysis of an RNAseq transcriptional atlas. Frontiers in Genetics, 10 1355. doi: 10.3389/fgene.2019.01355 |
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2020 Journal Article Using regulatory variants to detect gene-gene interactions identifies networks of genes linked to cell immortalisationWragg, D., Liu, Q., Lin, Z., Riggio, V., Pugh, C. A., Beveridge, A. J., Brown, H., Hume, D. A., Harris, S. E., Deary, I. J., Tenesa, A. and Prendergast, J. G.D. (2020). Using regulatory variants to detect gene-gene interactions identifies networks of genes linked to cell immortalisation. Nature Communications, 11 (1) 343. doi: 10.1038/s41467-019-13762-6 |
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2020 Journal Article The geometry of generalized loxodromic elementsAbbott, Carolyn R. and Hume, David (2020). The geometry of generalized loxodromic elements. Annales de l'Institut Fourier, 70 (4), 1689-1713. doi: 10.5802/AIF.3379 |
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2019 Journal Article Increased ultra-rare variant load in an isolated Scottish population impacts exonic and regulatory regionsHalachev, Mihail, Meynert, Alison, Taylor, Martin S., Vitart, Veronique, Kerr, Shona M., Klaric, Lucija, Consortium, S. G.P., Aitman, Timothy J., Haley, Chris S., Prendergast, James G., Pugh, Carys, Hume, David A., Harris, Sarah E., Liewald, David C., Deary, Ian J., Semple, Colin A. and Wilson, James F. (2019). Increased ultra-rare variant load in an isolated Scottish population impacts exonic and regulatory regions. PLoS Genetics, 15 (11) e1008480, e1008480. doi: 10.1371/journal.pgen.1008480 |
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2019 Journal Article Genetic and genomic analyses underpin the feasibility of concomitant genetic improvement of milk yield and mastitis resistance in dairy sheepBanos, Georgios, Clark, Emily L., Bush, Stephen J., Dutta, Prasun, Georgios Bramis, D., Arsenos, Georgios, Hume, David A. and Psifidi, Androniki (2019). Genetic and genomic analyses underpin the feasibility of concomitant genetic improvement of milk yield and mastitis resistance in dairy sheep. PLoS One, 14 (11) e0214346, e0214346. doi: 10.1371/journal.pone.0214346 |
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2019 Journal Article Analysis of the progeny of sibling matings reveals regulatory variation impacting the transcriptome of immune cells in commercial chickensFreem, Lucy, Summers, Kim M., Gheyas, Almas A., Psifidi, Androniki, Boulton, Kay, MacCallum, Amanda, Harne, Rakhi, O’Dell, Jenny, Bush, Stephen J. and Hume, David A. (2019). Analysis of the progeny of sibling matings reveals regulatory variation impacting the transcriptome of immune cells in commercial chickens. Frontiers in Genetics, 10 1032. doi: 10.3389/fgene.2019.01032 |
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2019 Journal Article A mini-atlas of gene expression for the domestic goat (Capra hircus)Muriuki, Charity, Bush, Stephen J., Salavati, Mazdak, McCulloch, Mary E.B., Lisowski, Zofia M., Agaba, Morris, Djikeng, Appolinaire, Hume, David A. and Clark, Emily L. (2019). A mini-atlas of gene expression for the domestic goat (Capra hircus). Frontiers in Genetics, 10 1080, 1080. doi: 10.3389/fgene.2019.01080 |
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2019 Journal Article Developmental stage-specific distribution of macrophages in mouse mammary glandStewart, Teneale A., Hughes, Katherine, Hume, David A. and Davis, Felicity M. (2019). Developmental stage-specific distribution of macrophages in mouse mammary gland. Frontiers in Cell and Developmental Biology, 7 250, 250. doi: 10.3389/fcell.2019.00250 |
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2019 Journal Article Antigen sampling CSF1R-expressing epithelial cells are the functional equivalents of mammalian m cells in the avian follicle-associated epitheliumBalic, Adam, Chintoan-Uta, Cosmin, Vohra, Prerna, Sutton, Kate M., Cassady-Cain, Robin L., Hu, Tuan, Donaldson, David S., Stevens, Mark P., Mabbott, Neil A., Hume, David A., Sang, Helen M. and Vervelde, Lonneke (2019). Antigen sampling CSF1R-expressing epithelial cells are the functional equivalents of mammalian m cells in the avian follicle-associated epithelium. Frontiers in Immunology, 10 (OCT) 2495, 2495. doi: 10.3389/fimmu.2019.02495 |
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2019 Journal Article Elimination of reference mapping bias reveals robust immune related allele-specific expression in crossbred sheepSalavati, Mazdak, Bush, Stephen J., Palma-Vera, Sergio, McCulloch, Mary E. B., Hume, David A. and Clark, Emily L. (2019). Elimination of reference mapping bias reveals robust immune related allele-specific expression in crossbred sheep. Frontiers in Genetics, 10 863, 863. doi: 10.3389/fgene.2019.00863 |
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2019 Journal Article Functional evolution of the colony‐stimulating factor 1 receptor (CSF1R) and its ligands in birdsHume, David A., Gutowska‐Ding, Maria W., Garcia‐Morales, Carla, Kebede, Adebabay, Bamidele, Oladeji, Trujillo, Adriana Vallejo, Gheyas, Almas A. and Smith, Jacqueline (2019). Functional evolution of the colony‐stimulating factor 1 receptor (CSF1R) and its ligands in birds. Journal of Leukocyte Biology, 107 (2) JLB.6MA0519-172R, 237-250. doi: 10.1002/jlb.6ma0519-172r |
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2019 Journal Article Analysis of the impact of CSF‐1 administration in adult rats using a novel Csf1r ‐mApple reporter geneIrvine, Katharine M., Caruso, Melanie, Cestari, Michelle Ferrari, Davis, Gemma M., Keshvari, Sahar, Sehgal, Anuj, Pridans, Clare and Hume, David A. (2019). Analysis of the impact of CSF‐1 administration in adult rats using a novel Csf1r ‐mApple reporter gene. Journal of Leukocyte Biology, 107 (2) JLB.MA0519-149R, 221-235. doi: 10.1002/jlb.ma0519-149r |
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2019 Journal Article Assembly of a parts list of the human mitotic cell cycle machineryGiotti, Bruno, Chen, Sz-Hau, Barnett, Mark W., Regan, Tim, Ly, Tony, Wiemann, Stefan, Hume, David A. and Freeman, Tom C. (2019). Assembly of a parts list of the human mitotic cell cycle machinery. Journal of Molecular Cell Biology, 11 (8), 703-718. doi: 10.1093/jmcb/mjy063 |
