|
2021 Journal Article Functions of macrophage colony-stimulating factor (CSF1) in development, homeostasis, and tissue repairSehgal, Anuj, Irvine, Katharine M. and Hume, David A. (2021). Functions of macrophage colony-stimulating factor (CSF1) in development, homeostasis, and tissue repair. Seminars in Immunology, 54 101509, 101509. doi: 10.1016/j.smim.2021.101509 |
|
2021 Journal Article Treatment with a long-acting chimeric CSF1 molecule enhances fracture healing of healthy and osteoporotic bonesBatoon, Lena, Millard, Susan M., Raggatt, Liza J., Sandrock, Cheyenne, Pickering, Edmund, Williams, Kyle, Sun, Lucas W.H., Wu, Andy C., Irvine, Katharine M., Pivonka, Peter, Glatt, Vaida, Wullschleger, Martin E., Hume, David A. and Pettit, Allison R. (2021). Treatment with a long-acting chimeric CSF1 molecule enhances fracture healing of healthy and osteoporotic bones. Biomaterials, 275 120936, 120936. doi: 10.1016/j.biomaterials.2021.120936 |
|
2021 Journal Article CSF1R-dependent macrophages control postnatal somatic growth and organ maturationKeshvari, Sahar, Caruso, Melanie, Teakle, Ngari, Batoon, Lena, Sehgal, Anuj, Patkar, Omkar L., Ferrari-Cestari, Michelle, Snell, Cameron E., Chen, Chen, Stevenson, Alex, Davis, Felicity M., Bush, Stephen J., Pridans, Clare, Summers, Kim M., Pettit, Allison R., Irvine, Katharine M. and Hume, David A. (2021). CSF1R-dependent macrophages control postnatal somatic growth and organ maturation. PLoS Genetics, 17 (6) e1009605, e1009605. doi: 10.1371/journal.pgen.1009605 |
|
2021 Journal Article Actions of small cancellation groups on hyperbolic spacesAbbott, Carolyn R. and Hume, David (2021). Actions of small cancellation groups on hyperbolic spaces. Geometriae Dedicata, 212 (1), 325-363. doi: 10.1007/s10711-020-00561-3 |
|
2021 Journal Article CRISPR-Cas9 editing of human histone deubiquitinase gene USP16 in human monocytic leukemia cell line THP-1Gažová, Iveta, Lefevre, Lucas, Bush, Stephen J., Rojo, Rocio, Hume, David A., Lengeling, Andreas and Summers, Kim M. (2021). CRISPR-Cas9 editing of human histone deubiquitinase gene USP16 in human monocytic leukemia cell line THP-1. Frontiers in Cell and Developmental Biology, 9 679544. doi: 10.3389/fcell.2021.679544 |
|
2021 Journal Article The mononuclear phagocyte system of the ratHume, David A., Caruso, Melanie, Keshvari, Sahar, Patkar, Omkar L., Sehgal, Anuj, Bush, Stephen J., Summers, Kim M., Pridans, Clare and Irvine, Katharine M. (2021). The mononuclear phagocyte system of the rat. The Journal of Immunology, 206 (10), 2251-2263. doi: 10.4049/jimmunol.2100136 |
|
2021 Journal Article Analysis of homozygous and heterozygous Csf1r knockout in the rat as a model for understanding microglial function in brain development and the impacts of human CSF1R mutationsPatkar, Omkar L., Caruso, Melanie, Teakle, Ngari, Keshvari, Sahar, Bush, Stephen J., Pridans, Clare, Belmer, Arnauld, Summers, Kim M., Irvine, Katharine M. and Hume, David A. (2021). Analysis of homozygous and heterozygous Csf1r knockout in the rat as a model for understanding microglial function in brain development and the impacts of human CSF1R mutations. Neurobiology of Disease, 151 105268, 105268. doi: 10.1016/j.nbd.2021.105268 |
|
2021 Journal Article The equine mononuclear phagocyte system: the relevance of the horse as a model for understanding human innate immunityKaragianni, Anna E., Lisowski, Zofia M., Hume, David A. and Scott Pirie, R. (2021). The equine mononuclear phagocyte system: the relevance of the horse as a model for understanding human innate immunity. Equine Veterinary Journal, 53 (2), 231-249. doi: 10.1111/evj.13341 |
|
2021 Journal Article Whole-genome sequence data suggest environmental adaptation of Ethiopian sheep populationsWiener, Pamela, Robert, Christelle, Ahbara, Abulgasim, Salavati, Mazdak, Abebe, Ayele, Kebede, Adebabay, Wragg, David, Friedrich, Juliane, Vasoya, Deepali, Hume, David A., Djikeng, Appolinaire, Watson, Mick, Prendergast, James G D, Hanotte, Olivier, Mwacharo, Joram M. and Clark, Emily L. (2021). Whole-genome sequence data suggest environmental adaptation of Ethiopian sheep populations. Genome Biology and Evolution, 13 (3) evab014, 1-18. doi: 10.1093/gbe/evab014 |
|
2021 Journal Article Transcriptomic analysis of rat macrophagesPridans, Clare, Irvine, Katharine M, Davis, Gemma M, Lefevre, Lucas, Bush, Stephen J and Hume, David A (2021). Transcriptomic analysis of rat macrophages. Frontiers in Immunology, 11 594594. doi: 10.3389/fimmu.2020.594594 |
|
2021 Journal Article On the utility of CSF1R inhibitorsGreen, Kim N. and Hume, David A. (2021). On the utility of CSF1R inhibitors. Proceedings of the National Academy of Sciences of the United States of America, 118 (4) e2019695118, 1-2. doi: 10.1073/pnas.2019695118 |
|
2021 Journal Article Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in miceKaur, Simranpreet, Sehgal, Anuj, Wu, Andy C., Millard, Susan M., Batoon, Lena, Sandrock, Cheyenne J., Ferrari-Cestari, Michelle, Levesque, Jean-Pierre, Hume, David A., Raggatt, Liza J. and Pettit, Allison R. (2021). Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice. Journal of Hematology and Oncology, 14 (1) 3, 1-19. doi: 10.1186/s13045-020-00997-w |
|
2020 Journal Article CNS macrophages differentially rely on an intronic Csf1r enhancer for their developmentMunro, David A.D., Bradford, Barry M., Mariani, Samanta A., Hampton, David W., Vink, Chris S., Chandran, Siddharthan, Hume, David A., Pridans, Clare and Priller, Josef (2020). CNS macrophages differentially rely on an intronic Csf1r enhancer for their development. Development, 147 (23) dev194449, 1-9. doi: 10.1242/dev.194449 |
|
2020 Journal Article Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domesticationDutta, Prasun, Talenti, Andrea, Young, Rachel, Jayaraman, Siddharth, Callaby, Rebecca, Jadhav, Santosh Kumar, Dhanikachalam, Velu, Manikandan, Mayakannan, Biswa, Bhim B., Low, Wai Y., Williams, John L., Cook, Elizabeth, Toye, Phil, Wall, Eileen, Djikeng, Appolinaire, Marshall, Karen, Archibald, Alan L., Gokhale, Suresh, Kumar, Satish, Hume, David A. and Prendergast, James G. D. (2020). Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domestication. Nature Communications, 11 (1) 4739. doi: 10.1038/s41467-020-18550-1 |
|
2020 Journal Article A transgenic line that reports CSF1R protein expression provides a definitive marker for the mouse mononuclear phagocyte systemGrabert, Kathleen, Sehgal, Anuj, Irvine, Katharine M., Wollscheid-Lengeling, Evi, Ozdemir, Derya D., Stables, Jennifer, Luke, Garry A., Ryan, Martin D., Adamson, Antony, Humphreys, Neil E., Sandrock, Cheyenne J., Rojo, Rocio, Verkasalo, Veera A., Mueller, Werner, Hohenstein, Peter, Pettit, Allison R., Pridans, Clare and Hume, David A. (2020). A transgenic line that reports CSF1R protein expression provides a definitive marker for the mouse mononuclear phagocyte system. Journal of Immunology, 205 (11), 3154-3166. doi: 10.4049/jimmunol.2000835 |
|
2020 Journal Article Poorly connected groupsHume, David and Mackay, John M. (2020). Poorly connected groups. Proceedings of the American Mathematical Society, 148 (11), 4653-4664. doi: 10.1090/proc/15128 |
|
2020 Journal Article Network analysis of transcriptomic diversity amongst resident tissue macrophages and dendritic cells in the mouse mononuclear phagocyte systemSummers, Kim M., Bush, Stephen J. and Hume, David A. (2020). Network analysis of transcriptomic diversity amongst resident tissue macrophages and dendritic cells in the mouse mononuclear phagocyte system. PLoS Biology, 18 (10) e3000859, 1-45. doi: 10.1371/journal.pbio.3000859 |
|
2020 Journal Article Measurement of serum Interleukin 34 (IL-34) and correlation with severity and pruritus scores in client-owned dogs with atopic dermatitisGow, Deborah J., Jackson, Hilary, Forsythe, Peter, Nuttall, Tim, Gow, Adam G., Mellanby, Richard J. and Hume, David A. (2020). Measurement of serum Interleukin 34 (IL-34) and correlation with severity and pruritus scores in client-owned dogs with atopic dermatitis. Veterinary Dermatology, 31 (5), 359-e94. doi: 10.1111/vde.12873 |
|
2020 Journal Article Expression of calcification and extracellular matrix genes in the cardiovascular system of the healthy domestic sheep (Ovis aries)Tsang, Hiu-Gwen, Clark, Emily L., Markby, Greg R., Bush, Stephen J., Hume, David A., Corcoran, Brendan M., MacRae, Vicky E. and Summers, Kim M. (2020). Expression of calcification and extracellular matrix genes in the cardiovascular system of the healthy domestic sheep (Ovis aries). Frontiers in Genetics, 11 919. doi: 10.3389/fgene.2020.00919 |
|
2020 Journal Article Immunohistochemical study of morphology and distribution of CD163+ve macrophages in the normal adult equine gastrointestinal tractLisowski, Zofia M., Sauter, Kristin A., Waddell, Lindsey A., Hume, David A., Pirie, R. Scott and Hudson, Neil P.H. (2020). Immunohistochemical study of morphology and distribution of CD163+ve macrophages in the normal adult equine gastrointestinal tract. Veterinary Immunology and Immunopathology, 226 110073, 110073. doi: 10.1016/j.vetimm.2020.110073 |
