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2019

Journal Article

Phenotypic impacts of CSF1R deficiencies in humans and model organisms

Hume, David A., Caruso, Melanie, Ferrari‐Cestari, Michelle, Summers, Kim M., Pridans, Clare and Irvine, Katharine M. (2019). Phenotypic impacts of CSF1R deficiencies in humans and model organisms. Journal of Leukocyte Biology, 107 (2) JLB.MR0519-143R, 205-219. doi: 10.1002/jlb.mr0519-143r

Phenotypic impacts of CSF1R deficiencies in humans and model organisms

2019

Journal Article

Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations

Rojo, Rocío, Raper, Anna, Ozdemir, Derya D., Lefevre, Lucas, Grabert, Kathleen, Wollscheid-Lengeling, Evi, Bradford, Barry, Caruso, Melanie, Gazova, Iveta, Sánchez, Alejandra, Lisowski, Zofia M., Alves, Joana, Molina-Gonzalez, Irene, Davtyan, Hayk, Lodge, Rebecca J., Glover, James D., Wallace, Robert, Munro, David A. D., David, Eyal, Amit, Ido, Miron, Véronique E., Priller, Josef, Jenkins, Stephen J., Hardingham, Giles E., Blurton-Jones, Mathew, Mabbott, Neil A., Summers, Kim M., Hohenstein, Peter, Hume, David A. and Pridans, Clare (2019). Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations. Nature Communications, 10 (1) 3215, 3215. doi: 10.1038/s41467-019-11053-8

Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations

2019

Journal Article

Erratum: Pleiotropic impacts of macrophage ands microglial deficiency on development in rats with targeted mutation of the Csf1r locus (Journal of Immunology (2019) 201 (2683-2699) DOI: 10.4049/jimmunol.1701783)

Pridans, Clare, Raper, Anna, Davis, Gemma M., Alves, Joana, Sauter, Kristin A., Lefevre, Lucas, Regan, Tim, Meek, Stephen, Sutherland, Linda, Thomson, Alison J., Clohisey, Sara, Bush, Stephen J., Rojo, Rocío, Lisowski, Zofia M., Wallace, Robert, Grabert, Kathleen, Upton, Kyle R., Tsai, Yi Ting, Brown, Deborah, Smith, Lee B., Summers, Kim M., Mabbott, Neil A., Piccardo, Pedro, Cheeseman, Michael T., Burdon, Tom and Hume, David A. (2019). Erratum: Pleiotropic impacts of macrophage ands microglial deficiency on development in rats with targeted mutation of the Csf1r locus (Journal of Immunology (2019) 201 (2683-2699) DOI: 10.4049/jimmunol.1701783). Journal of Immunology, 202 (11), 3334-3335. doi: 10.4049/jimmunol.1900420

Erratum: Pleiotropic impacts of macrophage ands microglial deficiency on development in rats with targeted mutation of the Csf1r locus (Journal of Immunology (2019) 201 (2683-2699) DOI: 10.4049/jimmunol.1701783)

2019

Journal Article

Examining the impact of imputation errors on fine-mapping using DNA methylation QTL as a model trait

Chundru, V. Kartik, Marioni, Riccardo E., Prendergast, James G. D., Vallerga, Costanza L., Lin, Tian, Berveridge, Allan J., SGPD Consortium, Gratten, Jacob, Hume, David A., Deary, Ian J., Wray, Naomi R., Visscher, Peter M. and McRae, Allan F. (2019). Examining the impact of imputation errors on fine-mapping using DNA methylation QTL as a model trait. Genetics, 212 (3), 577-586. doi: 10.1534/genetics.118.301861

Examining the impact of imputation errors on fine-mapping using DNA methylation QTL as a model trait

2019

Journal Article

The effect of race training on the basal gene expression of alveolar macrophages derived from Standardbred racehorses

Karagianni, Anna E., Summers, Kim M., Couroucé, Anne, Depecker, Marianne, McGorum, Bruce C., Hume, David A. and Pirie, R. Scott (2019). The effect of race training on the basal gene expression of alveolar macrophages derived from Standardbred racehorses. Journal of Equine Veterinary Science, 75, 48-54. doi: 10.1016/j.jevs.2019.01.010

The effect of race training on the basal gene expression of alveolar macrophages derived from Standardbred racehorses

2019

Journal Article

Measurement of serum macrophage migration inhibitory factor (MIF) and correlation with severity and pruritus scores in client owned dogs with atopic dermatitis

Gow, Debbie J., Jackson, Hilary, Forsythe, Peter, Gow, Adam G., Mellanby, Richard J., Hume, David A. and Nuttall, Tim (2019). Measurement of serum macrophage migration inhibitory factor (MIF) and correlation with severity and pruritus scores in client owned dogs with atopic dermatitis. Veterinary Dermatology, 30 (2), 115-e32. doi: 10.1111/vde.12721

Measurement of serum macrophage migration inhibitory factor (MIF) and correlation with severity and pruritus scores in client owned dogs with atopic dermatitis

2019

Journal Article

Correction to: Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza (Nature Immunology, (2018), 19, 6, (625-635), 10.1038/s41590-018-0111-5)

Dunning, Jake, Blankley, Simon, Hoang, Long T., Cox, Mike, Graham, Christine M., James, Philip L., Bloom, Chloe I., Chaussabel, Damien, Banchereau, Jacques, Brett, Stephen J., Habibi, Maximillian S., Johnston, Sebastian L., Hansel, Trevor T., Levin, Mike, Thwaites, Ryan S., Warner, John O., Cookson, William O., Gazzard, Brian G., Hay, Alan, McCauley, John, Aylin, Paul, Ashby, Deborah, Barclay, Wendy S., Elderfield, Ruth A., Nadel, Simon, Herberg, Jethro A., Drumright, Lydia N., Garcia-Alvarez, Laura, Holmes, Alison H. ... Openshaw, Peter J. M. (2019). Correction to: Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza (Nature Immunology, (2018), 19, 6, (625-635), 10.1038/s41590-018-0111-5). Nature Immunology, 20 (3), 373-373. doi: 10.1038/s41590-019-0328-y

Correction to: Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza (Nature Immunology, (2018), 19, 6, (625-635), 10.1038/s41590-018-0111-5)

2019

Journal Article

Relatively hyperbolic groups with fixed peripherals

Cordes, Matthew and Hume, David (2019). Relatively hyperbolic groups with fixed peripherals. Israel Journal of Mathematics, 230 (1), 443-470. doi: 10.1007/s11856-019-1830-5

Relatively hyperbolic groups with fixed peripherals

2019

Journal Article

Linked mutations at adjacent nucleotides have shaped human population differentiation and protein evolution

Prendergast, James G D, Pugh, Carys, Harris, Sarah E., Hume, David A., Deary, Ian J. and Beveridge, Allan (2019). Linked mutations at adjacent nucleotides have shaped human population differentiation and protein evolution. Genome Biology and Evolution, 11 (3), 759-775. doi: 10.1093/gbe/evz014

Linked mutations at adjacent nucleotides have shaped human population differentiation and protein evolution

2019

Journal Article

Causes and consequences of innate immune dysfunction in cirrhosis

Irvine, Katharine Margaret, Ratnasekera, Isanka, Powell, Elizabeth E. and Hume, David Arthur (2019). Causes and consequences of innate immune dysfunction in cirrhosis. Frontiers in Immunology, 10 (FEB) 293, 293. doi: 10.3389/fimmu.2019.00293

Causes and consequences of innate immune dysfunction in cirrhosis

2019

Journal Article

Characterization of subpopulations of chicken mononuclear phagocytes that express TIM4 and CSF1R

Hu, Tuanjun, Wu, Zhiguang, Bush, Stephen J., Freem, Lucy, Vervelde, Lonneke, Summers, Kim M., Hume, David A., Balic, Adam and Kaiser, Pete (2019). Characterization of subpopulations of chicken mononuclear phagocytes that express TIM4 and CSF1R. The Journal of Immunology, 202 (4), 1186-1199. doi: 10.4049/jimmunol.1800504

Characterization of subpopulations of chicken mononuclear phagocytes that express TIM4 and CSF1R

2019

Journal Article

Comprehensive transcriptional profiling of the gastrointestinal tract of ruminants from birth to adulthood reveals strong developmental stage specific gene expression

Bush, Stephen J., McCulloch, Mary E. B., Muriuki, Charity, Salavati, Mazdak, Davis, Gemma M., Farquhar, Iseabail L., Lisowski, Zofia M., Archibald, Alan L., Hume, David A. and Clark, Emily L. (2019). Comprehensive transcriptional profiling of the gastrointestinal tract of ruminants from birth to adulthood reveals strong developmental stage specific gene expression. G3: Genes, Genomes, Genetics, 9 (2), 359-373. doi: 10.1534/g3.118.200810

Comprehensive transcriptional profiling of the gastrointestinal tract of ruminants from birth to adulthood reveals strong developmental stage specific gene expression

2019

Journal Article

The mononuclear phagocyte system: the relationship between monocytes and macrophages

Hume, David A., Irvine, Katharine M. and Pridans, Clare (2019). The mononuclear phagocyte system: the relationship between monocytes and macrophages. Trends in Immunology, 40 (2), 98-112. doi: 10.1016/j.it.2018.11.007

The mononuclear phagocyte system: the relationship between monocytes and macrophages

2019

Journal Article

Chromosome-level assembly of the water buffalo genome surpasses human and goat genomes in sequence contiguity

Low, Wai Yee, Tearle, Rick, Bickhart, Derek M., Rosen, Benjamin D., Kingan, Sarah B., Swale, Thomas, Thibaud-Nissen, Françoise, Murphy, Terence D., Young, Rachel, Lefevre, Lucas, Hume, David A., Collins, Andrew, Ajmone-Marsan, Paolo, Smith, Timothy P. L. and Williams, John L. (2019). Chromosome-level assembly of the water buffalo genome surpasses human and goat genomes in sequence contiguity. Nature Communications, 10 (1) 260. doi: 10.1038/s41467-018-08260-0

Chromosome-level assembly of the water buffalo genome surpasses human and goat genomes in sequence contiguity

2019

Journal Article

Negative curvature in graphical small cancellation groups

Arzhantseva, Goulnara N., Cashen, Christopher H., Gruber, Dominik and Hume, David (2019). Negative curvature in graphical small cancellation groups. Groups, Geometry, and Dynamics, 13 (2), 579-632. doi: 10.4171/GGD/498

Negative curvature in graphical small cancellation groups

2019

Journal Article

Corrigendum: Causes and consequences of innate immune dysfunction in cirrhosis (Frontiers in Immunology (2019) 10 (293) DOI: 10.3389/fimmu.2019.00293)

Irvine, Katharine Margaret, Ratnasekera, Isanka, Powell, Elizabeth E. and Hume, David Arthur (2019). Corrigendum: Causes and consequences of innate immune dysfunction in cirrhosis (Frontiers in Immunology (2019) 10 (293) DOI: 10.3389/fimmu.2019.00293). Frontiers in Immunology, 10 (APR) 818, 818. doi: 10.3389/fimmu.2019.00818

Corrigendum: Causes and consequences of innate immune dysfunction in cirrhosis (Frontiers in Immunology (2019) 10 (293) DOI: 10.3389/fimmu.2019.00293)

2019

Journal Article

A gene expression atlas of the domestic water buffalo (Bubalus bubalis)

Young, Rachel, Lefevre, Lucas, Bush, Stephen J., Joshi, Akshay, Singh, Salam H., Jadhav, Santosh K., Lisowski, Zofia M., Iamartino, Daniela, Summers, Kim M., Williams, John L., Archibald, Alan L., Gokhale, Suresh, Kumar, Satish and Hume, David A. (2019). A gene expression atlas of the domestic water buffalo (Bubalus bubalis). Frontiers in Genetics, 10 (JUN) 668. doi: 10.3389/fgene.2019.00668

A gene expression atlas of the domestic water buffalo (Bubalus bubalis)

2018

Journal Article

A chicken bioreactor for efficient production of functional cytokines

Herron, Lissa R., Pridans, Clare, Turnbull, Matthew L., Smith, Nikki, Lillico, Simon, Sherman, Adrian, Gilhooley, Hazel J., Wear, Martin, Kurian, Dominic, Papadakos, Grigorios, Digard, Paul, Hume, David A., Gill, Andrew C. and Sang, Helen M. (2018). A chicken bioreactor for efficient production of functional cytokines. BMC Biotechnology, 18 (1) 82. doi: 10.1186/s12896-018-0495-1

A chicken bioreactor for efficient production of functional cytokines

2018

Journal Article

Dissecting the genomic architecture of resistance to Eimeria maxima parasitism in the chicken

Boulton, Kay, Nolan, Matthew J., Wu, Zhiguang, Riggio, Valentina, Matika, Oswald, Harman, Kimberley, Hocking, Paul M., Bumstead, Nat, Hesketh, Pat, Archer, Andrew, Bishop, Stephen C., Kaiser, Pete, Tomley, Fiona M., Hume, David A., Smith, Adrian L., Blake, Damer P. and Psifidi, Androniki (2018). Dissecting the genomic architecture of resistance to Eimeria maxima parasitism in the chicken. Frontiers in Genetics, 9 528, 528. doi: 10.3389/fgene.2018.00528

Dissecting the genomic architecture of resistance to Eimeria maxima parasitism in the chicken

2018

Journal Article

Phenotypic and genetic variation in the response of chickens to Eimeria tenella induced coccidiosis

Boulton, Kay, Nolan, Matthew J., Wu, Zhiguang, Psifidi, Androniki, Riggio, Valentina, Harman, Kimberley, Bishop, Stephen C., Kaiser, Pete, Abrahamsen, Mitchell S., Hawken, Rachel, Watson, Kellie A., Tomley, Fiona M., Blake, Damer P. and Hume, David A. (2018). Phenotypic and genetic variation in the response of chickens to Eimeria tenella induced coccidiosis. Genetics Selection Evolution, 50 (1) 63, 63. doi: 10.1186/s12711-018-0433-7

Phenotypic and genetic variation in the response of chickens to Eimeria tenella induced coccidiosis