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2016

Journal Article

A Csf1r-EGFP transgene provides a novel marker for monocyte subsets in sheep

Pridans, Clare, Davis, Gemma M., Sauter, Kristin A., Lisowski, Zofia M., Corripio-Miyar, Yolanda, Raper, Anna, Lefevre, Lucas, Young, Rachel, McCulloch, Mary E., Lillico, Simon, Milne, Elspeth, Whitelaw, Bruce and Hume, David A. (2016). A Csf1r-EGFP transgene provides a novel marker for monocyte subsets in sheep. Journal of Immunology, 197 (6), 2297-2305. doi: 10.4049/jimmunol.1502336

A Csf1r-EGFP transgene provides a novel marker for monocyte subsets in sheep

2016

Journal Article

Macrophage colony-stimulating factor (CSF1) controls monocyte production and maturation and the steady-state size of the liver in pigs

Sauter, Kristin A., Waddell, Lindsey A., Lisowski, Zofia M., Young, Rachel, Lefevre, Lucas, Davis, Gemma M., Clohisey, Sara M., McCulloch, Mary, Magowan, Elizabeth, Mabbott, Neil A., Summers, Kim M. and Hume, David A. (2016). Macrophage colony-stimulating factor (CSF1) controls monocyte production and maturation and the steady-state size of the liver in pigs. American Journal of Physiology - Gastrointestinal and Liver Physiology, 311 (3), G533-G547. doi: 10.1152/ajpgi.00116.2016

Macrophage colony-stimulating factor (CSF1) controls monocyte production and maturation and the steady-state size of the liver in pigs

2016

Journal Article

Resting and injury-induced inflamed periosteum contain multiple macrophage subsets that are located at sites of bone growth and regeneration

Alexander, Kylie Anne, Raggatt, Liza-Jane, Millard, Susan, Batoon, Lena, Wu, Andy Chiu-Ku, Chang, Ming-Kang, Hume, David Arthur and Pettit, Allison Robyn (2016). Resting and injury-induced inflamed periosteum contain multiple macrophage subsets that are located at sites of bone growth and regeneration. Immunology and Cell Biology, 95 (1), 7-16. doi: 10.1038/icb.2016.74

Resting and injury-induced inflamed periosteum contain multiple macrophage subsets that are located at sites of bone growth and regeneration

2016

Journal Article

Role of bone marrow macrophages in controlling homeostasis and repair in bone and bone marrow niches

Kaur, Simranpreet, Raggatt, Liza Jane, Batoon, Lena, Hume, David Arthur, Levesque, Jean-Pierre and Pettit, Allison Robyn (2016). Role of bone marrow macrophages in controlling homeostasis and repair in bone and bone marrow niches. Seminars in Cell and Developmental Biology, 61, 12-21. doi: 10.1016/j.semcdb.2016.08.009

Role of bone marrow macrophages in controlling homeostasis and repair in bone and bone marrow niches

2016

Journal Article

Comparative transcriptome analysis of equine alveolar macrophages

Karagianni, A. E., Kapetanovic, R., Summers, K. M., Mcgorum, B. C., Hume, D. A. and Pirie, R. S. (2016). Comparative transcriptome analysis of equine alveolar macrophages. Equine Veterinary Journal, 49 (3), 375-382. doi: 10.1111/evj.12584

Comparative transcriptome analysis of equine alveolar macrophages

2016

Journal Article

Functional annotation of the T-cell immunoglobulin mucin family in birds

Hu, Tuanjun, Wu, Zhiguang, Vervelde, Lonneke, Rothwell, Lisa, Hume, David A. and Kaiser, Pete (2016). Functional annotation of the T-cell immunoglobulin mucin family in birds. Immunology, 148 (3), 287-303. doi: 10.1111/imm.12607

Functional annotation of the T-cell immunoglobulin mucin family in birds

2016

Journal Article

Transcriptional regulation and macrophage differentiation

Hume, David A., Summers, Kim M. and Rehli, Michael (2016). Transcriptional regulation and macrophage differentiation. Microbiology Spectrum, 4 (3) MCHD-0024-2015, 1-19. doi: 10.1128/microbiolspec.MCHD-0024-2015

Transcriptional regulation and macrophage differentiation

2016

Journal Article

Induction of interferon and cell death in response to cytosolic DNA in chicken macrophages

Vitak, Nazarii, Hume, David A., Chappell, Keith J., Sester, David P. and Stacey, Katryn J. (2016). Induction of interferon and cell death in response to cytosolic DNA in chicken macrophages. Developmental and Comparative Immunology, 59, 145-152. doi: 10.1016/j.dci.2016.01.023

Induction of interferon and cell death in response to cytosolic DNA in chicken macrophages

2016

Journal Article

Analysis of the function of IL-10 in chickens using specific neutralising antibodies and a sensitive capture ELISA

Wu, Zhiguang, Hu, Tuanjun, Rothwell, Lisa, Vervelde, Lonneke, Kaiser, Pete, Boulton, Kay, Nolan, Matthew J., Tomley, Fiona M., Blake, Damer P. and Hume, David A. (2016). Analysis of the function of IL-10 in chickens using specific neutralising antibodies and a sensitive capture ELISA. Developmental and Comparative Immunology, 63, 206-212. doi: 10.1016/j.dci.2016.04.016

Analysis of the function of IL-10 in chickens using specific neutralising antibodies and a sensitive capture ELISA

2016

Journal Article

Enhancer turnover is associated with a divergent transcriptional response to glucocorticoid in mouse and human macrophages

Jubb, Alasdair W., Young, Robert S., Hume, David A. and Bickmore, Wendy A. (2016). Enhancer turnover is associated with a divergent transcriptional response to glucocorticoid in mouse and human macrophages. Journal of Immunology, 196 (2), 813-822. doi: 10.4049/jimmunol.1502009

Enhancer turnover is associated with a divergent transcriptional response to glucocorticoid in mouse and human macrophages

2016

Journal Article

The genomic architecture of resistance to Campylobacter jejuni intestinal colonisation in chickens

Psifidi, A., Fife, M., Howell, J., Matika, O., van Diemen, P. M., Kuo, R., Smith, J., Hocking, P. M., Salmon, N., Jones, M. A., Hume, D. A., Banos, G., Stevens, M. P. and Kaiser, P. (2016). The genomic architecture of resistance to Campylobacter jejuni intestinal colonisation in chickens. BMC Genomics, 17 (293) 293. doi: 10.1186/s12864-016-2612-7

The genomic architecture of resistance to Campylobacter jejuni intestinal colonisation in chickens

2015

Journal Article

The constrained maximal expression level owing to haploidy shapes gene content on the mammalian X chromosome

Hurst, Laurence D., Ghanbarian, Avazeh T., Forrest, Alistair R. R., Huminiecki, Lukasz, Rehli, Michael, Baillie, J. Kenneth, de Hoon, Michiel J. L., Haberle, Vanja, Lassmann, Timo, Kulakovskiy, Ivan V., Lizio, Marina, Itoh, Masayoshi, Andersson, Robin, Mungall, Christopher J., Meehan, Terrence F., Schmeier, Sebastian, Bertin, Nicolas, Jorgensen, Mette, Dimont, Emmanuel, Arner, Erik, Schmidl, Christian, Schaefer, Ulf, Medvedeva, Yulia A., Plessy, Charles, Vitezic, Morana, Severin, Jessica, Semple, Colin A., Ishizu, Yuri, Young, Robert S. ... Hayashizaki, Yoshihide (2015). The constrained maximal expression level owing to haploidy shapes gene content on the mammalian X chromosome. PLoS Biology, 13 (12) e1002315, e1002315. doi: 10.1371/journal.pbio.1002315

The constrained maximal expression level owing to haploidy shapes gene content on the mammalian X chromosome

2015

Journal Article

CSF1 restores innate immunity after liver injury in mice and serum levels indicate outcomes of patients with acute liver failure

Stutchfield, Benjamin M., Antoine, Daniel J., Mackinnon, Alison C., Gow, Deborah J., Bain, Calum C., Hawley, Catherine A., Hughes, Michael J., Francis, Benjamin, Wojtacha, Davina, Man, Tak Y., Dear, James W., Devey, Luke R., Mowat, Alan M., Pollard, Jeffrey W., Park, B. Kevin, Jenkins, Stephen J., Simpson, Kenneth J., Hume, David A., Wigmore, Stephen J. and Forbes, Stuart J. (2015). CSF1 restores innate immunity after liver injury in mice and serum levels indicate outcomes of patients with acute liver failure. Gastroenterology, 149 (7), 1896-1909. doi: 10.1053/j.gastro.2015.08.053

CSF1 restores innate immunity after liver injury in mice and serum levels indicate outcomes of patients with acute liver failure

2015

Journal Article

Identification and annotation of conserved promoters and macrophage-expressed genes in the pig genome

Robert, Christelle, Kapetanovic, Ronan, Beraldi, Dario, Watson, Mick, Archibald, Alan L. and Hume, David A. (2015). Identification and annotation of conserved promoters and macrophage-expressed genes in the pig genome. BMC Genomics, 16 (1) 970, 970.1-970.17. doi: 10.1186/s12864-015-2111-2

Identification and annotation of conserved promoters and macrophage-expressed genes in the pig genome

2015

Journal Article

Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity

Modhiran, Naphak, Watterson, Daniel, Muller, David A., Panetta, Adele K., Sester, David P., Liu, Lidong, Hume, David A., Stacey, Katryn J. and Young, Paul R. (2015). Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity. Science Translational Medicine, 7 (304) 304ra142, 1-10. doi: 10.1126/scitranslmed.aaa3863

Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity

2015

Journal Article

The many alternative faces of macrophage activation

Hume, David A. (2015). The many alternative faces of macrophage activation. Frontiers in Immunology, 6 (JUL) 370. doi: 10.3389/fimmu.2015.00370

The many alternative faces of macrophage activation

2015

Journal Article

Immune surveillance of the lung by migrating tissue monocytes

Rodero, Mathieu P., Poupel, Lucie, Loyher, Pierre-Louis, Hamon, Pauline, Licata, Fabrice, Pessel, Charlotte, Hume, David A., Combadière, Christophe and Boissonnas, Alexandre (2015). Immune surveillance of the lung by migrating tissue monocytes. eLife, 4 (JULY 2015) e07847, 1-23. doi: 10.7554/eLife.07847

Immune surveillance of the lung by migrating tissue monocytes

2015

Journal Article

Direct embeddings of relatively hyperbolic groups with optimal ℓp compression exponent

Hume, David (2015). Direct embeddings of relatively hyperbolic groups with optimal ℓp compression exponent. Journal fur die Reine und Angewandte Mathematik, 2015 (703), 147-172. doi: 10.1515/crelle-2013-0040

Direct embeddings of relatively hyperbolic groups with optimal ℓp compression exponent

2015

Journal Article

Plant breeding: UK bioscientists push for crop policy

Hume, David (2015). Plant breeding: UK bioscientists push for crop policy. Nature, 521 (7553), 423-423. doi: 10.1038/521423c

Plant breeding: UK bioscientists push for crop policy

2015

Journal Article

Transcriptional dynamics reveal critical roles for non-coding RNAs in the immediate-early response

Aitken, Stuart, Magi, Shigeyuki, Alhendi, Ahmad M. N., Itoh, Masayoshi, Kawaji, Hideya, Lassmann, Timo, Daub, Carsten O., Arner, Erik, Carninci, Piero, Forrest, Alistair R. R., Hayashizaki, Yoshihide, Khachigian, Levon M., Okada-Hatakeyama, Mariko, Semple, Colin A., FANTOM Consortium, Forrest, Alistair R. R., Sandelin, Albin, Daub, Carsten O., Wells, Christine, Hume, David A., Arner, Erik, Kawaji, Hideya, Summers, Kim M., Vitting-Seerup, Kristoffer, Carninci, Piero, Andersson, Robin, Hayashizaki, Yoshihide and Yumoto, Noriko (2015). Transcriptional dynamics reveal critical roles for non-coding RNAs in the immediate-early response. PLoS Computational Biology, 11 (4) e1004217, e1004217. doi: 10.1371/journal.pcbi.1004217

Transcriptional dynamics reveal critical roles for non-coding RNAs in the immediate-early response