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2017 Journal Article Ryanodine receptor modification and regulation by intracellular Ca2+ and Mg2+ in healthy and failing human heartsWalweel, K., Molenaar, P., Imtiaz, M. S., Denniss, A., dos Remedios, C., van Helden, D. F., Dulhunty, A. F., Laver, D. R. and Beard, N. A. (2017). Ryanodine receptor modification and regulation by intracellular Ca2+ and Mg2+ in healthy and failing human hearts. Journal of Molecular and Cellular Cardiology, 104, 53-62. doi: 10.1016/j.yjmcc.2017.01.016 |
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2015 Journal Article Cardiac gene expression data and in silico analysis provide novel insights into human and mouse taste receptor gene regulationFoster, Simon R., Porrello, Enzo R., Stefani, Maurizio, Smith, Nicola J., Molenaar, Peter, Dos Remedios, Cristobal G., Thomas, Walter G. and Ramialison, Mirana (2015). Cardiac gene expression data and in silico analysis provide novel insights into human and mouse taste receptor gene regulation. Naunyn-Schmiedeberg's Archives of Pharmacology, 388 (10) 1118, 1009-1027. doi: 10.1007/s00210-015-1118-1 |
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2015 Journal Article G protein-coupled receptors in cardiac biology: old and new receptorsFoster, Simon R, Roura, Eugeni, Molenaar, Peter and Thomas, Walter G. (2015). G protein-coupled receptors in cardiac biology: old and new receptors. Biophysical Reviews, 7 (1), 77-89. doi: 10.1007/s12551-014-0154-2 |
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2015 Conference Publication Transcriptional Regulation of Taste Receptor Genes: Novel Insights From In Silico and Cardiac Gene Expression AnalysesFoster, Simon R., Porrello, Enzo R., Stefani, Maurizio, Smith, Nicola J., Molenaar, Peter, dos Remedios, Cris G., Thomas, Walter G. and Ramialison, Mirana (2015). Transcriptional Regulation of Taste Receptor Genes: Novel Insights From In Silico and Cardiac Gene Expression Analyses. 15th Scientific Meeting of the Australasian Association for ChemoSensory Science (AACSS), Brisbane, QLD Australia, 03-05 December 2014. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/chemse/bjv008 |
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2014 Journal Article Differences in the regulation of RyR2 from human, sheep, and rat by Ca2+ and Mg2+ in the cytoplasm and in the lumen of the sarcoplasmic reticulumWalweel, Kafa, Li, Jiao, Molenaar, Peter, Imtiaz, Mohammad S., Quail, Anthony, dos Remedios, Cris G., Beard, Nicole A., Dulhunty, Angela F., van Helden, Dirk F. and Laver, Derek R. (2014). Differences in the regulation of RyR2 from human, sheep, and rat by Ca2+ and Mg2+ in the cytoplasm and in the lumen of the sarcoplasmic reticulum. Journal of General Physiology, 144 (3), 263-271. doi: 10.1085/jgp.201311157 |
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2014 Journal Article Carvedilol induces greater control of β2- than β1-adrenoceptor-mediated inotropic and lusitropic effects by PDE3, while PDE4 has no effect in human failing myocardiumMolenaar, Peter, Christ, Torsten, Berk, Emanuel, Engel, Andreas, Gillette, Katherine T., Galindo-Tovar, Alejandro, Ravens, Ursula and Kaumann, Alberto J. (2014). Carvedilol induces greater control of β2- than β1-adrenoceptor-mediated inotropic and lusitropic effects by PDE3, while PDE4 has no effect in human failing myocardium. Naunyn-Schmiedeberg's Archives of Pharmacology, 387 (7), 629-640. doi: 10.1007/s00210-014-0974-4 |
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2013 Journal Article Chronic activation of the low affinity site of beta(1)-adrenoceptors stimulates haemodynamics but exacerbates pressure-overload cardiac remodellingKiriazis, Helen, Tugiono, Niquita, Xu, Qi, Gao, Xiao-Ming, Jennings, Nicole L., Ming, Ziqui, Su, Yidan, Klenowski, Paul, Summers, Roger J., Kaumann, Alberto, Molenaar, Peter and Du, Xiao-Jun (2013). Chronic activation of the low affinity site of beta(1)-adrenoceptors stimulates haemodynamics but exacerbates pressure-overload cardiac remodelling. British Journal of Pharmacology, 170 (2), 352-365. doi: 10.1111/bph.12272 |
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2013 Journal Article PDE3, but not PDE4, reduces beta 1- and beta 2-adrenoceptor-mediated inotropic and lusitropic effects in failing ventricle from metoprolol-treated patientsMolenaar, Peter, Christ, Torsten, Hussain, Rizwan I., Engel, Andreas, Berk, Emanuel, Gillette, Katherine T., Chen, Lu, Galindo-Tovar, Alejandro, Krobert, Kurt A., Ravens, Ursula, Levy, Finn Olav and Kaumann, Alberto J. (2013). PDE3, but not PDE4, reduces beta 1- and beta 2-adrenoceptor-mediated inotropic and lusitropic effects in failing ventricle from metoprolol-treated patients. British Journal of Pharmacology, 169 (3), 528-538. doi: 10.1111/bph.12167 |
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2013 Journal Article Expression, Regulation and Putative Nutrient-Sensing Function of Taste GPCRs in the HeartFoster, Simon R., Porrello, Enzo R., Purdue, Brooke, Chan, Hsiu-Wen, Voigt, Anja, Frenzel, Sabine, Hannan, Ross D., Moritz, Karen M., Simmons, David G., Molenaar, Peter, Roura, Eugeni, Boehm, Ulrich, Meyerhof, Wolfgang and Thomas, Walter G. (2013). Expression, Regulation and Putative Nutrient-Sensing Function of Taste GPCRs in the Heart. PLoS ONE, 8 (5) e64579, e64579-1-e64579-10. doi: 10.1371/journal.pone.0064579 |
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2013 Conference Publication The role of beta1 adrenoceptors in the development of alcohol dependenceKlenowski, P. M., Holgate, J., Bellingham, M., Molenaar, P. and Bartlett, S. (2013). The role of beta1 adrenoceptors in the development of alcohol dependence. Neuroscience 2013: 43rd Annual Meeting of the Society for Neuroscience, San Diego, CA, USA, 9-13 November, 2013. |
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2011 Journal Article Computer three-dimensional anatomical reconstruction of the human sinus node and a novel paranodal areaChandler, Natalie, Aslanidi, Oleg, Buckley, David, Inada, Shin, Birchall, Steven, Atkinson, Andrew, Kirk, Danielle, Monfredi, Oliver, Molenaar, Peter, Anderson, Robert, Sharma, Vinod, Sigg, Daniel, Zhang, Henggui, Boyett, Mark and Dobrzynski, Halina (2011). Computer three-dimensional anatomical reconstruction of the human sinus node and a novel paranodal area. Anatomical Record, 294 (6), 970-979. doi: 10.1002/ar.21379 |
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2011 Journal Article Molecular architecture of the human specialised atrioventricular conduction axisGreener, I. D., Monfredi, O., Inada, S., Chandler, N. J, Tellez, J.O., Atkinson, A., Taube, M. A., Billeter, R., Anderson, R. H., Efimov, I. R., Molenaar, P., Sigg, D. C., Sharma, V., Boyett, M. R. and Dobrzynski, H. (2011). Molecular architecture of the human specialised atrioventricular conduction axis. Journal of Molecular and Cellular Cardiology, 50 (4), 642-651. doi: 10.1016/j.yjmcc.2010.12.017 |
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2011 Journal Article Human atrial β 1L-adrenoceptor but not β 3- adrenoceptor activation increases force and Ca 2+ current at physiological temperatureChrist, Torsten, Molenaar, Peter, Klenowski, Paul M., Ravens, Ursula and Kaumann, Alberto J. (2011). Human atrial β 1L-adrenoceptor but not β 3- adrenoceptor activation increases force and Ca 2+ current at physiological temperature. British Journal of Pharmacology, 162 (4), 823-839. doi: 10.1111/j.1476-5381.2010.00996.x |
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2009 Journal Article P2 purinergic receptor mRNA in rat and human sinoatrial node and other heart regionsMusa, Hanny, Tellez, James O., Chandler, Natalie J., Greener, Ian D., Maczewski, Michał, Mackiewicz, Urszula, Beresewicz, Andrzej, Molenaar, Peter, Boyett, Mark R. and Dobrzynski, Halina (2009). P2 purinergic receptor mRNA in rat and human sinoatrial node and other heart regions. Naunyn-Schmiedeberg's Archives of Pharmacology, 379 (6), 541-549. doi: 10.1007/s00210-009-0403-2 |
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2009 Journal Article Molecular Architecture of the Human Sinus Node Insights Into the Function of the Cardiac PacemakerChandler, Natalie J., Greener, Ian D., Tellez, James O., Inada, Shin, Musa, Hanny, Molenaar, Peter, DiFrancesco, Dario, Baruscotti, Mirko, Longhi, Renato, Anderson, Robert H., Billeter, Rudolf, Sharma, Vinod, Sigg, Daniel C., Boyett, Mark R. and Dobrzynski, Halina (2009). Molecular Architecture of the Human Sinus Node Insights Into the Function of the Cardiac Pacemaker. Circulation, 119 (12), 1562-1575. doi: 10.1161/CIRCULATIONAHA.108.804369 |
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2008 Journal Article The low-affinity site of the β1-adrenoceptor and its relevance to cardiovascular pharmacologyKaumann, Alberto J. and Molenaar, Peter (2008). The low-affinity site of the β1-adrenoceptor and its relevance to cardiovascular pharmacology. Pharmacology and Therapeutics, 118 (3), 303-336. doi: 10.1016/j.pharmthera.2008.03.009 |
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2007 Journal Article Arg389Gly-beta(1)-adrenergic receptors determine improvement in left ventricular systolic function in nonischemic cardiomyopathy patients with heart failure after chronic treatment with carvedilolCheng lu, Meyers, Deborah, Javorsky, George, Bursto, Darryl, Lolekha, Pakorn, Lucas, Margaret, Semmler, Annalese B. T., Savarimuthu, Santiyagu M., Fong, Kwun M., Yang, Ian A., Atherton, John, Galbraith, Andrew J., Parsonage, William A. and Molenaar, Peter (2007). Arg389Gly-beta(1)-adrenergic receptors determine improvement in left ventricular systolic function in nonischemic cardiomyopathy patients with heart failure after chronic treatment with carvedilol. Pharmacogenetics And Genomics, 17 (11), 941-949. doi: 10.1097/FPC.0b013e3282ef7354 |
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2007 Journal Article Human heart beta-adrenoceptors: beta(1)-adrenoceptor diversification through 'affinity states' and polymorphismMolenaar, P., Chen, L., Semmler, A. B. T., Parsonage, W. A. and Kaumann, A. J. (2007). Human heart beta-adrenoceptors: beta(1)-adrenoceptor diversification through 'affinity states' and polymorphism. Clinical And Experimental Pharmacology And Physiology, 34 (10), 1020-1028. doi: 10.1111/j.1440-1681.2007.04730.x |
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2007 Journal Article beta(2)-adrenoceptor polymorphisms and obstructive airway diseases: Important issues of study designYang, Ian A., Ng, Taria, Molenaar, Peter and Fong, Kwun M. (2007). beta(2)-adrenoceptor polymorphisms and obstructive airway diseases: Important issues of study design. Clinical And Experimental Pharmacology and Physiology, 34 (10), 1029-1036. doi: 10.1111/j.1440-1681.2007.04731.x |
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2007 Journal Article The effects of both noradrenaline and CGP12177, mediated through human beta(1)-adrenoceptors, are reduced by PDE3 in human atrium but PDE4 in CHO cellsKaumann, Alberto, Semmler, Annalese B. T. and Molenaar, Peter (2007). The effects of both noradrenaline and CGP12177, mediated through human beta(1)-adrenoceptors, are reduced by PDE3 in human atrium but PDE4 in CHO cells. Naunyn-schmiedebergs Archives of Pharmacology, 375 (2), 123-131. doi: 10.1007/s00210-007-0140-3 |
